BICLUSTER_ID : UPREG-228
PATHOGENS /7/ : pseudomonas aeruginosa,brucella neotomae,escherichia coli,bifidobacterium bifidum,streptococcus pneumoniae,brucella ovis,mycobacterium tuberculosis
TARGETS /3/ : NFKB1, IL6, PTGS2
Gene SetLeading Edge Genes
NETPATH IL 1 PATHWAY UPNFKB1, BIRC3, IL6, PTGS2, CXCL2, SOD2
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
ONDER CDH1 TARGETS 3 DN
ZHOU INFLAMMATORY RESPONSE LIVE UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
MAHAJAN RESPONSE TO IL1A UP
WEINMANN ADAPTATION TO HYPOXIA DN
NETPATH IL 6 PATHWAY UP
LINDSTEDT DENDRITIC CELL MATURATION B
CROONQUIST STROMAL STIMULATION UP
DAZARD UV RESPONSE CLUSTER G2
NETPATH IL 5 PATHWAY UP
FOSTER INFLAMMATORY RESPONSE LPS DN
AMIT SERUM RESPONSE 40 MCF10A
LINDSTEDT DENDRITIC CELL MATURATION A
NETPATH IL 1 PATHWAY
SEKI INFLAMMATORY RESPONSE LPS UP
HELLER SILENCED BY METHYLATION UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
NETPATH TNF ALPHA PATHWAY UP
NETPATH IL 7 PATHWAY UP
SANA TNF SIGNALING UP
MAHADEVAN RESPONSE TO MP470 DN
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
BROWNE INTERFERON RESPONSIVE GENES
SESTO RESPONSE TO UV C3
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
VERHAAK AML WITH NPM1 MUTATED UP
GEISS RESPONSE TO DSRNA UP
HINATA NFKB TARGETS KERATINOCYTE UP
DIRMEIER LMP1 RESPONSE LATE UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
ST TUMOR NECROSIS FACTOR PATHWAY
DASU IL6 SIGNALING UP
AMIT SERUM RESPONSE 60 MCF10A
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
DUTTA APOPTOSIS VIA NFKB
NETPATH IL 2 PATHWAY UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
COULOUARN TEMPORAL TGFB1 SIGNATURE UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
DIRMEIER LMP1 RESPONSE EARLY
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN
AMIT EGF RESPONSE 60 MCF10A
FERRARI RESPONSE TO FENRETINIDE UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
streptococcus pneumoniae g54bifidobacterium bifidumpseudomonas aeruginosamycobacterium tuberculosisbrucella ovisbrucella neotomaeescherichia coliGeneSet Name
0.02186 0.00007 0.00004 0.00602 0.01452 0.00114 0.00000NETPATH_IL_1_PATHWAY_UP
0.01878 0.01391 0.00003 0.00000 0.01964 0.00128 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.03102 0.01033 0.00003 0.10086 0.00115 0.01819 0.00000ONDER_CDH1_TARGETS_3_DN
0.11282 0.00000 0.00000 0.00002 0.00746 0.01309 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.03257 0.00214 0.01558 0.00002 0.07308 0.03682 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.01466 0.00402 0.00184 0.00000 0.12378 0.02726 0.00046AMIT_EGF_RESPONSE_120_HELA
0.03237 0.00011 0.00006 0.00000 0.10980 0.00155 0.00003DAUER_STAT3_TARGETS_UP
0.01216 0.00000 0.00126 0.00000 0.03860 0.01035 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.08911 0.00474 0.00000 0.00132 0.08148 0.16767 0.00000MAHAJAN_RESPONSE_TO_IL1A_UP
0.00875 0.01898 0.03347 0.03354 0.07459 0.18229 0.00000WEINMANN_ADAPTATION_TO_HYPOXIA_DN
0.01842 0.00007 0.01244 0.00000 0.01065 0.01660 0.00000NETPATH_IL_6_PATHWAY_UP
0.00817 0.00000 0.00005 0.00000 0.02851 0.02410 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.09861 0.01386 0.01456 0.00025 0.01979 0.00132 0.00003CROONQUIST_STROMAL_STIMULATION_UP
0.03619 0.03296 0.01158 0.01541 0.14937 0.00657 0.00004DAZARD_UV_RESPONSE_CLUSTER_G2
0.07746 0.11144 0.00238 0.00000 0.03173 0.12369 0.00001NETPATH_IL_5_PATHWAY_UP
0.01680 0.00000 0.00185 0.00000 0.01159 0.00621 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00737 0.01845 0.00028 0.00000 0.08142 0.03264 0.00142AMIT_SERUM_RESPONSE_40_MCF10A
0.16372 0.00005 0.00387 0.00000 0.00044 0.00010 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.03624 0.03028 0.00603 0.03544 0.08064 0.10960 0.00003NETPATH_IL_1_PATHWAY
0.02093 0.00000 0.00000 0.00000 0.00076 0.00041 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.17361 0.02743 0.17408 0.00000 0.11472 0.10277 0.00002HELLER_SILENCED_BY_METHYLATION_UP
0.11160 0.00000 0.00000 0.00000 0.05672 0.07552 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00231 0.00000 0.00000 0.00000 0.00055 0.00387 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.07319 0.11156 0.01390 0.00534 0.15651 0.10261 0.00001NETPATH_TNF_ALPHA_PATHWAY_UP
0.11486 0.01764 0.00151 0.00856 0.01316 0.01290 0.00000NETPATH_IL_7_PATHWAY_UP
0.15203 0.00000 0.00000 0.00000 0.01931 0.00058 0.00000SANA_TNF_SIGNALING_UP
0.15502 0.00016 0.00187 0.00000 0.06080 0.00665 0.00317MAHADEVAN_RESPONSE_TO_MP470_DN
0.09013 0.07330 0.00381 0.00000 0.06140 0.01038 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.11107 0.00000 0.10336 0.00000 0.12548 0.00715 0.00000BROWNE_INTERFERON_RESPONSIVE_GENES
0.01104 0.00136 0.00703 0.00000 0.12374 0.04591 0.00001SESTO_RESPONSE_TO_UV_C3
0.00067 0.02116 0.00000 0.00000 0.00038 0.00059 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.12533 0.02011 0.00267 0.00000 0.08159 0.03242 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.03258 0.00426 0.00051 0.00000 0.08028 0.01183 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.00568 0.00013 0.00000 0.00000 0.03817 0.09086 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.06964 0.10056 0.12927 0.00003 0.03254 0.16770 0.00000DIRMEIER_LMP1_RESPONSE_LATE_UP
0.00000 0.08234 0.00002 0.00000 0.01384 0.00256 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.17463 0.00000 0.00004 0.00060 0.05857 0.00378 0.00000KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.03498 0.00006 0.00006 0.00000 0.08843 0.03927 0.00000BASSO_CD40_SIGNALING_UP
0.10551 0.00028 0.00000 0.00010 0.06146 0.09858 0.00026ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.09369 0.05109 0.00000 0.00006 0.14484 0.12777 0.00015DASU_IL6_SIGNALING_UP
0.00321 0.15969 0.00092 0.00001 0.11740 0.11766 0.00109AMIT_SERUM_RESPONSE_60_MCF10A
0.08229 0.00012 0.00251 0.02521 0.00716 0.01093 0.00037SOUCEK_MYC_TARGETS
0.16057 0.00000 0.00000 0.00000 0.02617 0.05899 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.05455 0.00215 0.00086 0.00002 0.01264 0.00644 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.16635 0.07512 0.11013 0.00008 0.18663 0.17779 0.00000NETPATH_IL_2_PATHWAY_UP
0.03864 0.00000 0.00000 0.00002 0.00040 0.00010 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00641 0.02296 0.16056 0.02560 0.08879 0.11146 0.01809COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP
0.01851 0.01525 0.00003 0.00000 0.01906 0.00123 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.06587 0.02142 0.00093 0.13990 0.15857 0.17189 0.00010LEE_LIVER_CANCER_HEPATOBLAST
0.01824 0.03751 0.00002 0.00039 0.10002 0.01371 0.00000ZUCCHI_METASTASIS_DN
0.00045 0.09324 0.00102 0.00000 0.19801 0.01336 0.00003NAGASHIMA_EGF_SIGNALING_UP
0.08905 0.00294 0.00000 0.00000 0.01330 0.00214 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.06179 0.05799 0.06344 0.00205 0.05093 0.15401 0.00492CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN
0.00090 0.00467 0.00367 0.00004 0.03197 0.02489 0.00000AMIT_EGF_RESPONSE_60_MCF10A
0.01205 0.05329 0.00003 0.00018 0.08101 0.02413 0.00016FERRARI_RESPONSE_TO_FENRETINIDE_UP