BICLUSTER_ID : UPREG-236
PATHOGENS /8/ : escherichia coli,lactobacillus acidophilus,streptococcus pyogenes,aeromonas caviae,bifidobacterium bifidum,streptococcus pneumoniae,mycobacterium tuberculosis,ehrlichia chaffeensis
TARGETS /1/ : STAT1
Gene SetLeading Edge Genes
NETPATH IL 6 PATHWAY UPSTAT1, IRF1, MAP3K8, NMI
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP
SANA RESPONSE TO IFNG UP
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
MAHAJAN RESPONSE TO IL1A UP
DER IFN ALPHA RESPONSE UP
PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN
LINDSTEDT DENDRITIC CELL MATURATION B
NETPATH IL 5 PATHWAY UP
LEE LIVER CANCER E2F1 UP
FOSTER INFLAMMATORY RESPONSE LPS DN
SEKI INFLAMMATORY RESPONSE LPS UP
LINDSTEDT DENDRITIC CELL MATURATION A
HELLER SILENCED BY METHYLATION UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
NETPATH IL 7 PATHWAY UP
SANA TNF SIGNALING UP
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN UP
RUTELLA RESPONSE TO CSF2RB AND IL4 DN
BROWNE INTERFERON RESPONSIVE GENES
NCI IL6 7PATHWAY
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP
CASTELLANO NRAS TARGETS UP
VERHAAK AML WITH NPM1 MUTATED UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN
DER IFN BETA RESPONSE UP
MORI PRE BI LYMPHOCYTE DN
ST TYPE I INTERFERON PATHWAY
GEISS RESPONSE TO DSRNA UP
HINATA NFKB TARGETS KERATINOCYTE UP
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
MARKEY RB1 ACUTE LOF UP
JISON SICKLE CELL DISEASE UP
GALI TP53 TARGETS APOPTOTIC UP
BASSO CD40 SIGNALING UP
HESS TARGETS OF HOXA9 AND MEIS1 DN
SOUCEK MYC TARGETS
NUYTTEN EZH2 TARGETS UP
HUMMEL BURKITTS LYMPHOMA DN
NETPATH IL 2 PATHWAY UP
DUTTA APOPTOSIS VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP
DIRMEIER LMP1 RESPONSE EARLY
ZHAN MULTIPLE MYELOMA LB DN
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
lactobacillus acidophilusbifidobacterium bifidumaeromonas caviaehrlichia chaffeensis arkansastreptococcus pneumoniae g54mycobacterium tuberculosisstreptococcus pyogenesescherichia coliGeneSet Name
0.00006 0.00007 0.10211 0.00003 0.01842 0.00000 0.00001 0.00000NETPATH_IL_6_PATHWAY_UP
0.12763 0.08197 0.11676 0.00123 0.01828 0.00000 0.18510 0.01985RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
0.00000 0.00000 0.00000 0.00000 0.15101 0.00000 0.00000 0.00000SANA_RESPONSE_TO_IFNG_UP
0.00259 0.00011 0.05120 0.01097 0.03237 0.00000 0.00038 0.00003DAUER_STAT3_TARGETS_UP
0.00000 0.00000 0.00001 0.00001 0.01216 0.00000 0.00099 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.00430 0.00474 0.16652 0.01198 0.08911 0.00132 0.17839 0.00000MAHAJAN_RESPONSE_TO_IL1A_UP
0.00000 0.00081 0.00000 0.00000 0.11860 0.00000 0.00000 0.00000DER_IFN_ALPHA_RESPONSE_UP
0.07538 0.11301 0.03029 0.02780 0.04093 0.00008 0.00128 0.09136PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN
0.00000 0.00000 0.00053 0.00007 0.00817 0.00000 0.02304 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.01533 0.11144 0.07327 0.00007 0.07746 0.00000 0.03974 0.00001NETPATH_IL_5_PATHWAY_UP
0.00852 0.00724 0.01675 0.00000 0.05639 0.00014 0.01561 0.00843LEE_LIVER_CANCER_E2F1_UP
0.00000 0.00000 0.00001 0.00000 0.01680 0.00000 0.00568 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.00000 0.00002 0.00000 0.02093 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00005 0.00124 0.00000 0.16372 0.00000 0.00032 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00489 0.02743 0.00206 0.00000 0.17361 0.00000 0.00113 0.00002HELLER_SILENCED_BY_METHYLATION_UP
0.00000 0.00000 0.00001 0.00000 0.00231 0.00000 0.00019 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.06237 0.01764 0.16616 0.00034 0.11486 0.00856 0.04416 0.00000NETPATH_IL_7_PATHWAY_UP
0.00000 0.00000 0.00000 0.00000 0.15203 0.00000 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.00374 0.00489 0.02237 0.03161 0.10354 0.00000 0.00011 0.00057ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP
0.10725 0.10663 0.02718 0.00000 0.03089 0.00000 0.02986 0.12734RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN
0.00000 0.00000 0.00000 0.00000 0.11107 0.00000 0.00000 0.00000BROWNE_INTERFERON_RESPONSIVE_GENES
0.12322 0.08284 0.07318 0.00000 0.10802 0.00288 0.00000 0.00785NCI_IL6_7PATHWAY
0.00000 0.00000 0.00000 0.00000 0.08161 0.00000 0.00000 0.00000TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP
0.00308 0.00034 0.02086 0.00014 0.11522 0.00316 0.00217 0.00040CASTELLANO_NRAS_TARGETS_UP
0.03043 0.02011 0.08932 0.00000 0.12533 0.00000 0.01128 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00372 0.00139 0.16527 0.00081 0.13995 0.00000 0.13253 0.00220TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.00020 0.00457 0.00001 0.00000 0.12500 0.00000 0.00016 0.00002FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN
0.00144 0.02261 0.00003 0.00030 0.11870 0.00000 0.00032 0.00000DER_IFN_BETA_RESPONSE_UP
0.04496 0.17576 0.00014 0.00013 0.00687 0.00014 0.06972 0.04300MORI_PRE_BI_LYMPHOCYTE_DN
0.05556 0.08675 0.09960 0.00856 0.04474 0.06313 0.10462 0.13309ST_TYPE_I_INTERFERON_PATHWAY
0.00027 0.00426 0.00364 0.00175 0.03258 0.00000 0.01876 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.00013 0.06206 0.00055 0.00568 0.00000 0.05930 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00001 0.00145 0.00399 0.00015 0.03598 0.00000 0.19908 0.00000GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.00000 0.00000 0.00000 0.00000 0.10730 0.00000 0.00000 0.00000MARKEY_RB1_ACUTE_LOF_UP
0.00011 0.00331 0.00632 0.00000 0.04179 0.00000 0.00066 0.00023JISON_SICKLE_CELL_DISEASE_UP
0.00830 0.03207 0.05625 0.05198 0.11520 0.17731 0.04180 0.04486GALI_TP53_TARGETS_APOPTOTIC_UP
0.00000 0.00006 0.00110 0.00000 0.03498 0.00000 0.00023 0.00000BASSO_CD40_SIGNALING_UP
0.04650 0.09533 0.01035 0.00000 0.13868 0.00000 0.00000 0.08966HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00010 0.00012 0.00169 0.00003 0.08229 0.02521 0.00021 0.00037SOUCEK_MYC_TARGETS
0.00089 0.00779 0.07444 0.00475 0.00276 0.00000 0.10005 0.00000NUYTTEN_EZH2_TARGETS_UP
0.02581 0.06060 0.11042 0.00212 0.05491 0.00035 0.02106 0.00005HUMMEL_BURKITTS_LYMPHOMA_DN
0.01173 0.07512 0.07215 0.00029 0.16635 0.00008 0.01602 0.00000NETPATH_IL_2_PATHWAY_UP
0.00233 0.00215 0.05340 0.00000 0.05455 0.00002 0.02575 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.00000 0.00000 0.09323 0.00001 0.03864 0.00002 0.05507 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.01593 0.11780 0.00108 0.00000 0.10106 0.00002 0.01025 0.00008BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP
0.00007 0.00294 0.00564 0.00000 0.08905 0.00000 0.00616 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00182 0.01616 0.00000 0.00000 0.08960 0.00000 0.00000 0.00002ZHAN_MULTIPLE_MYELOMA_LB_DN