BICLUSTER_ID : UPREG-244
PATHOGENS /5/ : brucella neotomae,bifidobacterium bifidum,streptococcus pyogenes,brucella melitensis,ehrlichia chaffeensis
TARGETS /4/ : IL1B, CCL5, CCL2, CD86
Gene SetLeading Edge Genes
NETPATH IL 3 PATHWAY UPSOCS3, IL1B, CCL3, CCL2, CD86
NETPATH IL 5 PATHWAY UPPLSCR1, BIRC3, CCL3, IL1B, CCL2, IER3
NCI IL23PATHWAYSOCS3, IL1B, CCL2
NETPATH KIT RECEPTOR PATHWAY UPCCL5, CCL2, IER3
NETPATH IL 1 PATHWAY UPCHI3L1, BIRC3, IL1B, MT2A, CCL2, CXCL2
NETPATH IL 9 PATHWAY UPSOCS3, CCL3, CCL2
NETPATH IL 4 PATHWAY DOWNGADD45B, CCL2, CXCL2, GBP2
NETPATH IL 7 PATHWAY UPCCL3, CD86, CXCL2
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
BENNETT SYSTEMIC LUPUS ERYTHEMATOSUS
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NETPATH IL 6 PATHWAY UPSOCS3, GADD45B, JUNB
KEGG GRAFT VERSUS HOST DISEASE
MCLACHLAN DENTAL CARIES UP
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
LINDSTEDT DENDRITIC CELL MATURATION B
FOSTER INFLAMMATORY RESPONSE LPS DN
MCLACHLAN DENTAL CARIES DN
KEGG ALLOGRAFT REJECTION
LINDSTEDT DENDRITIC CELL MATURATION A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
RADAEVA RESPONSE TO IFNA1 UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
BROWNE HCMV INFECTION 4HR UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHOU INFLAMMATORY RESPONSE LPS UP
BOWIE RESPONSE TO EXTRACELLULAR MATRIX
SANA TNF SIGNALING UP
MOSERLE IFNA RESPONSE
FOSTER INFLAMMATORY RESPONSE LPS UP
AMIT SERUM RESPONSE 120 MCF10A
LEE LIVER CANCER MYC E2F1 UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 2
HARRIS HYPOXIA
PEPPER CHRONIC LYMPHOCYTIC LEUKEMIA UP
VERHAAK AML WITH NPM1 MUTATED UP
DER IFN BETA RESPONSE UP
GEISS RESPONSE TO DSRNA UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
HINATA NFKB TARGETS KERATINOCYTE UP
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
HESS TARGETS OF HOXA9 AND MEIS1 DN
MARZEC IL2 SIGNALING UP
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
ZHU CMV ALL UP
DUTTA APOPTOSIS VIA NFKB
NETPATH IL 2 PATHWAY UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
GOLDRATH ANTIGEN RESPONSE
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
ehrlichia chaffeensis wakullabrucella melitensisbifidobacterium bifidumstreptococcus pyogenesbrucella neotomaeehrlichia chaffeensis libertyGeneSet Name
0.00000 0.00052 0.01084 0.00095 0.00000 0.00030NETPATH_IL_3_PATHWAY_UP
0.00000 0.01177 0.11144 0.03974 0.12369 0.05924NETPATH_IL_5_PATHWAY_UP
0.00020 0.03782 0.00000 0.00014 0.04130 0.00440NCI_IL23PATHWAY
0.00015 0.02966 0.08735 0.02708 0.05217 0.05936NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00022 0.00061 0.00007 0.03192 0.00114 0.04640NETPATH_IL_1_PATHWAY_UP
0.00000 0.00000 0.00572 0.00011 0.00066 0.00207NETPATH_IL_9_PATHWAY_UP
0.00000 0.00471 0.00103 0.00471 0.00269 0.00340NETPATH_IL_4_PATHWAY_DOWN
0.00004 0.02550 0.01764 0.04416 0.01290 0.00005NETPATH_IL_7_PATHWAY_UP
0.00000 0.10177 0.00000 0.00010 0.17773 0.00077KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00000 0.19040 0.00000 0.00004 0.07917 0.00011BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS
0.00307 0.00563 0.00011 0.00038 0.00155 0.06350DAUER_STAT3_TARGETS_UP
0.00000 0.18585 0.00000 0.00099 0.01035 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.00000 0.00163 0.00007 0.00001 0.01660 0.00150NETPATH_IL_6_PATHWAY_UP
0.00000 0.00487 0.00101 0.01019 0.06507 0.00002KEGG_GRAFT_VERSUS_HOST_DISEASE
0.00000 0.01108 0.00155 0.00000 0.00479 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.00000 0.03772 0.00000 0.00000 0.00537 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.00000 0.01411 0.00000 0.02304 0.02410 0.02223LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00000 0.00031 0.00000 0.00568 0.00621 0.00078FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.01946 0.00444 0.00000 0.00595 0.00000MCLACHLAN_DENTAL_CARIES_DN
0.00014 0.09553 0.00011 0.03176 0.14303 0.00019KEGG_ALLOGRAFT_REJECTION
0.00000 0.00644 0.00005 0.00032 0.00010 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00000 0.00010 0.00000 0.00000 0.00041 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00642 0.00007 0.00000 0.00119 0.00000GAURNIER_PSMD4_TARGETS
0.00000 0.09499 0.00000 0.00000 0.14758 0.00009RADAEVA_RESPONSE_TO_IFNA1_UP
0.00003 0.02218 0.00000 0.05533 0.07552 0.00022GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.01785 0.13602 0.10226 0.06323 0.00980 0.07524BROWNE_HCMV_INFECTION_4HR_UP
0.00000 0.00017 0.00000 0.00019 0.00387 0.00059ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00012 0.02743 0.00000 0.06782 0.02297 0.03822ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00166 0.18600 0.00216 0.00020 0.17499 0.00412BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX
0.00000 0.00362 0.00000 0.00000 0.00058 0.00008SANA_TNF_SIGNALING_UP
0.00000 0.10219 0.00000 0.00000 0.02846 0.00000MOSERLE_IFNA_RESPONSE
0.00000 0.09817 0.00000 0.00000 0.09836 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.00009 0.00478 0.07807 0.09332 0.11404 0.00533AMIT_SERUM_RESPONSE_120_MCF10A
0.00000 0.14130 0.02392 0.01825 0.14464 0.00544LEE_LIVER_CANCER_MYC_E2F1_UP
0.00174 0.00944 0.07330 0.11415 0.01038 0.01294THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00004 0.00468 0.02116 0.09492 0.00059 0.02652HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00000 0.06677 0.00000 0.00000 0.02175 0.00004TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP
0.00974 0.08894 0.00313 0.07017 0.18802 0.09153SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2
0.00025 0.04905 0.05400 0.15102 0.17495 0.03906HARRIS_HYPOXIA
0.00161 0.05160 0.13461 0.00227 0.13097 0.03685PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP
0.00000 0.01897 0.02011 0.01128 0.03242 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00214 0.03901 0.02261 0.00032 0.05335 0.08872DER_IFN_BETA_RESPONSE_UP
0.00022 0.09792 0.00426 0.01876 0.01183 0.01274GEISS_RESPONSE_TO_DSRNA_UP
0.00252 0.05929 0.00006 0.04007 0.00835 0.05665KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00001 0.05127 0.00013 0.05930 0.09086 0.00058HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00050 0.13111 0.14936 0.01687 0.11004 0.17607SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1
0.00000 0.03717 0.00000 0.02604 0.00378 0.00966KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.04270 0.00006 0.00023 0.03927 0.00000BASSO_CD40_SIGNALING_UP
0.00000 0.14126 0.09533 0.00000 0.15914 0.00000HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00004 0.01700 0.02397 0.13526 0.08610 0.04723MARZEC_IL2_SIGNALING_UP
0.00027 0.00824 0.00012 0.00021 0.01093 0.00038SOUCEK_MYC_TARGETS
0.00000 0.00659 0.00000 0.00455 0.05899 0.02222TIAN_TNF_SIGNALING_VIA_NFKB
0.00083 0.10116 0.03180 0.06342 0.00066 0.06440ZHU_CMV_ALL_UP
0.00000 0.00246 0.00215 0.02575 0.00644 0.00023DUTTA_APOPTOSIS_VIA_NFKB
0.00006 0.03203 0.07512 0.01602 0.17779 0.01786NETPATH_IL_2_PATHWAY_UP
0.00009 0.00050 0.00000 0.05507 0.00010 0.00033GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.00015 0.00294 0.00616 0.00214 0.00342DIRMEIER_LMP1_RESPONSE_EARLY
0.00001 0.15514 0.00318 0.01593 0.09849 0.00131MAHADEVAN_RESPONSE_TO_MP470_UP
0.00000 0.03198 0.00000 0.04429 0.02834 0.00725GOLDRATH_ANTIGEN_RESPONSE
0.00000 0.02236 0.00006 0.00007 0.00575 0.00023REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.00000 0.04288 0.00442 0.00000 0.00947 0.00181SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP