BICLUSTER_ID : UPREG-268
PATHOGENS /5/ : pseudomonas aeruginosa,streptococcus pneumoniae,lactobacillus acidophilus,yersinia enterocolitica,streptococcus pyogenes
TARGETS /1/ : IL6
Gene SetLeading Edge Genes
NETPATH IL 1 PATHWAY UPIL6, CXCL1, ZFP36, CXCL2
NOJIMA SFRP2 TARGETS UP
MISSIAGLIA REGULATED BY METHYLATION UP
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
BIOCARTA RANKL PATHWAY
MAHAJAN RESPONSE TO IL1A UP
NETPATH IL 6 PATHWAY UPZFP36, MAP3K8
LINDSTEDT DENDRITIC CELL MATURATION B
NETPATH IL 5 PATHWAY UP
FOSTER INFLAMMATORY RESPONSE LPS DN
RASHI RESPONSE TO IONIZING RADIATION 2
CHARAFE BREAST CANCER BASAL VS MESENCHYMAL UP
SEKI INFLAMMATORY RESPONSE LPS UP
LINDSTEDT DENDRITIC CELL MATURATION A
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
NETPATH IL 7 PATHWAY UP
ONDER CDH1 TARGETS 2 DN
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
VERHAAK AML WITH NPM1 MUTATED UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
HARRIS HYPOXIA
GEISS RESPONSE TO DSRNA UP
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
HINATA NFKB TARGETS KERATINOCYTE UP
GERY CEBP TARGETS
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
HESS TARGETS OF HOXA9 AND MEIS1 DN
DASU IL6 SIGNALING UP
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
NETPATH IL 2 PATHWAY UP
DUTTA APOPTOSIS VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
ZUCCHI METASTASIS DN
DIRMEIER LMP1 RESPONSE EARLY
PRAMOONJAGO SOX4 TARGETS UP
HINATA NFKB TARGETS FIBROBLAST UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bl6yersinia enterocolitica p60 bl6yersinia enterocolitica p60 bclactobacillus acidophilusstreptococcus pneumoniae g54streptococcus pyogenespseudomonas aeruginosastreptococcus pneumoniae tigr4GeneSet Name
0.00024 0.00000 0.00001 0.00114 0.02186 0.03192 0.00004 0.00001NETPATH_IL_1_PATHWAY_UP
0.00172 0.00037 0.00304 0.00685 0.17017 0.08281 0.06631 0.00000NOJIMA_SFRP2_TARGETS_UP
0.00468 0.00038 0.00145 0.00001 0.00810 0.01557 0.00002 0.05746MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.05660 0.06189 0.02597 0.00259 0.03237 0.00038 0.00006 0.00000DAUER_STAT3_TARGETS_UP
0.00000 0.00000 0.00000 0.00000 0.01216 0.00099 0.00126 0.13850LIANG_SILENCED_BY_METHYLATION_2
0.05455 0.07528 0.01255 0.00384 0.11238 0.08751 0.01532 0.05739BIOCARTA_RANKL_PATHWAY
0.00113 0.00010 0.00009 0.00430 0.08911 0.17839 0.00000 0.00006MAHAJAN_RESPONSE_TO_IL1A_UP
0.00000 0.00000 0.00000 0.00006 0.01842 0.00001 0.01244 0.00000NETPATH_IL_6_PATHWAY_UP
0.04571 0.04591 0.00237 0.00000 0.00817 0.02304 0.00005 0.00796LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.02712 0.00711 0.00159 0.01533 0.07746 0.03974 0.00238 0.00002NETPATH_IL_5_PATHWAY_UP
0.00000 0.00000 0.00000 0.00000 0.01680 0.00568 0.00185 0.01424FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00427 0.00297 0.00008 0.00034 0.00271 0.00000 0.00000 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.05300 0.12910 0.11761 0.07959 0.00269 0.09568 0.16853 0.12258CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP
0.00000 0.00000 0.00000 0.00000 0.02093 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00011 0.00029 0.00000 0.00000 0.16372 0.00032 0.00387 0.15403LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00810 0.00398 0.00030 0.00000 0.11160 0.05533 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00000 0.00000 0.00231 0.00019 0.00000 0.00001ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00623 0.00709 0.00028 0.06237 0.11486 0.04416 0.00151 0.00009NETPATH_IL_7_PATHWAY_UP
0.00065 0.00022 0.00011 0.02211 0.00297 0.16233 0.00503 0.10479ONDER_CDH1_TARGETS_2_DN
0.00024 0.00184 0.00000 0.09352 0.09013 0.11415 0.00381 0.00077THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00080 0.00030 0.00006 0.11701 0.00067 0.09492 0.00000 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00001 0.00000 0.00000 0.03043 0.12533 0.01128 0.00267 0.01022VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.01109 0.00708 0.00004 0.00372 0.13995 0.13253 0.13363 0.07760TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.00250 0.00029 0.00029 0.18721 0.10031 0.15102 0.00391 0.00000HARRIS_HYPOXIA
0.00179 0.00109 0.00000 0.00027 0.03258 0.01876 0.00051 0.03793GEISS_RESPONSE_TO_DSRNA_UP
0.00514 0.00272 0.00007 0.00001 0.03598 0.19908 0.02559 0.00170GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.00000 0.00000 0.00000 0.00000 0.00568 0.05930 0.00000 0.00741HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00277 0.00040 0.00510 0.00427 0.12493 0.01652 0.00843 0.00001GERY_CEBP_TARGETS
0.00045 0.00058 0.00008 0.00000 0.17463 0.02604 0.00004 0.02561KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00018 0.00003 0.00000 0.03498 0.00023 0.00006 0.01887BASSO_CD40_SIGNALING_UP
0.00000 0.00006 0.00004 0.04650 0.13868 0.00000 0.15886 0.00000HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.01073 0.00177 0.00020 0.15237 0.09369 0.04449 0.00000 0.00007DASU_IL6_SIGNALING_UP
0.00000 0.00018 0.00008 0.00010 0.08229 0.00021 0.00251 0.02991SOUCEK_MYC_TARGETS
0.00000 0.00016 0.00000 0.00000 0.16057 0.00455 0.00000 0.00001TIAN_TNF_SIGNALING_VIA_NFKB
0.01769 0.00994 0.00018 0.01173 0.16635 0.01602 0.11013 0.07061NETPATH_IL_2_PATHWAY_UP
0.00646 0.00201 0.00013 0.00233 0.05455 0.02575 0.00086 0.00090DUTTA_APOPTOSIS_VIA_NFKB
0.00024 0.00037 0.00000 0.00000 0.03864 0.05507 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.08451 0.04370 0.05022 0.04132 0.01824 0.01684 0.00002 0.00000ZUCCHI_METASTASIS_DN
0.00000 0.00018 0.00000 0.00007 0.08905 0.00616 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.02502 0.02844 0.00119 0.00031 0.00000 0.19931 0.00151 0.00000PRAMOONJAGO_SOX4_TARGETS_UP
0.03435 0.00034 0.00008 0.01167 0.02432 0.14412 0.00000 0.00038HINATA_NFKB_TARGETS_FIBROBLAST_UP