BICLUSTER_ID : UPREG-274
PATHOGENS /5/ : bifidobacterium bifidum,yersinia enterocolitica,porphyromonas gingivalis,streptococcus pyogenes,ehrlichia chaffeensis
TARGETS /5/ : IL6, IL12B, IL1B, CCL2, CD86
Gene SetLeading Edge Genes
NETPATH IL 3 PATHWAY UPSOCS3, CCL7, IL1B, CCL2, CD86
NCI IL23PATHWAYSOCS3, IL6, IL1B, CXCL1, CCL2
NCI IL27PATHWAYIL12B, IL6, IL1B
NETPATH IL 4 PATHWAY DOWNIL6, GADD45B, CCL2
NETPATH IL 9 PATHWAY UPSOCS3, CCL7, CCL2
NETPATH IL 7 PATHWAY UPCXCL5, CXCL1, CD86
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
NOJIMA SFRP2 TARGETS UP
DAUER STAT3 TARGETS UP
LIAN LIPA TARGETS 6M
NETPATH IL 6 PATHWAY UPSOCS3, GADD45B
KEGG GRAFT VERSUS HOST DISEASE
MCLACHLAN DENTAL CARIES UP
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS
KEGG ASTHMA
WU HBX TARGETS 1 UP
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
LINDSTEDT DENDRITIC CELL MATURATION B
MCLACHLAN DENTAL CARIES DN
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
SEKI INFLAMMATORY RESPONSE LPS UP
WALLACE PROSTATE CANCER RACE UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
SMID BREAST CANCER LUMINAL B DN
GESERICK TERT TARGETS DN
AMIT SERUM RESPONSE 120 MCF10A
ONDER CDH1 TARGETS 2 DN
TSAI RESPONSE TO RADIATION THERAPY
BIOCARTA TH1TH2 PATHWAY
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
KEGG HEMATOPOIETIC CELL LINEAGE
KEGG JAK STAT SIGNALING PATHWAY
HARRIS HYPOXIA
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
BROCKE APOPTOSIS REVERSED BY IL6
REACTOME G ALPHA I SIGNALLING EVENTS
BOYAULT LIVER CANCER SUBCLASS G56 DN
GEISS RESPONSE TO DSRNA UP
HINATA NFKB TARGETS KERATINOCYTE UP
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
REACTOME GPCR LIGAND BINDING
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
BIOCARTA DC PATHWAY
BIOCARTA IL22BP PATHWAY
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
LU IL4 SIGNALING
WU HBX TARGETS 2 DN
DIRMEIER LMP1 RESPONSE EARLY
AMIT DELAYED EARLY GENES
MAHADEVAN RESPONSE TO MP470 UP
SMID BREAST CANCER NORMAL LIKE UP
HINATA NFKB TARGETS FIBROBLAST UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bcehrlichia chaffeensis arkansaehrlichia chaffeensis wakullabifidobacterium bifidumstreptococcus pyogenesporphyromonas gingivalisGeneSet Name
0.00000 0.00000 0.00000 0.01084 0.00095 0.12641NETPATH_IL_3_PATHWAY_UP
0.00001 0.00000 0.00020 0.00000 0.00014 0.00584NCI_IL23PATHWAY
0.00720 0.00000 0.00004 0.00000 0.00027 0.07257NCI_IL27PATHWAY
0.00024 0.00001 0.00000 0.00103 0.00471 0.00395NETPATH_IL_4_PATHWAY_DOWN
0.00001 0.00097 0.00000 0.00572 0.00011 0.01126NETPATH_IL_9_PATHWAY_UP
0.00052 0.00034 0.00004 0.01764 0.04416 0.01741NETPATH_IL_7_PATHWAY_UP
0.00001 0.00000 0.00000 0.00000 0.00010 0.00839KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00224 0.01772 0.00340 0.00005 0.08281 0.11857NOJIMA_SFRP2_TARGETS_UP
0.06147 0.01097 0.00307 0.00011 0.00038 0.00811DAUER_STAT3_TARGETS_UP
0.00074 0.00000 0.00000 0.04912 0.00004 0.09798LIAN_LIPA_TARGETS_6M
0.00000 0.00003 0.00000 0.00007 0.00001 0.09273NETPATH_IL_6_PATHWAY_UP
0.00024 0.00000 0.00000 0.00101 0.01019 0.15597KEGG_GRAFT_VERSUS_HOST_DISEASE
0.00000 0.00000 0.00000 0.00155 0.00000 0.08054MCLACHLAN_DENTAL_CARIES_UP
0.05073 0.00034 0.00004 0.05369 0.00068 0.00871REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS
0.04376 0.06161 0.00288 0.00982 0.01985 0.03097KEGG_ASTHMA
0.00334 0.02293 0.11208 0.02956 0.18465 0.11831WU_HBX_TARGETS_1_UP
0.00741 0.00094 0.00014 0.01762 0.00032 0.09297REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.00004 0.00007 0.00000 0.00000 0.02304 0.02335LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00001 0.00000 0.00000 0.00444 0.00000 0.08235MCLACHLAN_DENTAL_CARIES_DN
0.00001 0.00307 0.00001 0.00098 0.00000 0.02386RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00000 0.00000 0.00000 0.00005 0.00032 0.00457LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00000 0.00000 0.00000 0.00000 0.00000 0.00125SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.00000 0.00167 0.00000 0.19031WALLACE_PROSTATE_CANCER_RACE_UP
0.00000 0.00000 0.00000 0.00000 0.00019 0.00127ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00824 0.00000 0.00000 0.13028 0.05508 0.04544SMID_BREAST_CANCER_LUMINAL_B_DN
0.00000 0.00047 0.00032 0.05480 0.01538 0.03305GESERICK_TERT_TARGETS_DN
0.00000 0.04018 0.00009 0.07807 0.09332 0.00000AMIT_SERUM_RESPONSE_120_MCF10A
0.00111 0.00757 0.00036 0.09938 0.16233 0.07092ONDER_CDH1_TARGETS_2_DN
0.01725 0.02983 0.00053 0.00063 0.02614 0.09812TSAI_RESPONSE_TO_RADIATION_THERAPY
0.07845 0.00111 0.00009 0.00394 0.00388 0.03346BIOCARTA_TH1TH2_PATHWAY
0.00000 0.00262 0.00004 0.02116 0.09492 0.05737HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00344 0.00000 0.00000 0.03856 0.00468 0.02431KEGG_HEMATOPOIETIC_CELL_LINEAGE
0.00277 0.01019 0.00097 0.00000 0.00074 0.12580KEGG_JAK_STAT_SIGNALING_PATHWAY
0.00004 0.00160 0.00025 0.05400 0.15102 0.08079HARRIS_HYPOXIA
0.00012 0.00081 0.00001 0.00139 0.13253 0.12409TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.00001 0.00000 0.00000 0.02793 0.00074 0.14398BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.10388 0.00009 0.00052 0.09003 0.01622 0.15518REACTOME_G_ALPHA_I_SIGNALLING_EVENTS
0.06378 0.00017 0.00184 0.16391 0.05417 0.03820BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN
0.00000 0.00175 0.00022 0.00426 0.01876 0.12681GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.00055 0.00001 0.00013 0.05930 0.00133HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00011 0.00015 0.00030 0.00145 0.19908 0.01492GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.17594 0.01722 0.01107 0.07753 0.01560 0.02865REACTOME_GPCR_LIGAND_BINDING
0.00001 0.00003 0.00027 0.00012 0.00021 0.03916SOUCEK_MYC_TARGETS
0.00000 0.00003 0.00000 0.00000 0.00455 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.07276 0.00147 0.01675 0.00573 0.01251 0.00361BIOCARTA_DC_PATHWAY
0.04920 0.01255 0.02837 0.00102 0.01117 0.06447BIOCARTA_IL22BP_PATHWAY
0.00000 0.00001 0.00009 0.00000 0.05507 0.09753GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00006 0.00276 0.00009 0.01831 0.14418 0.06609LU_IL4_SIGNALING
0.08739 0.02731 0.00094 0.10021 0.02682 0.09838WU_HBX_TARGETS_2_DN
0.00000 0.00000 0.00000 0.00294 0.00616 0.00483DIRMEIER_LMP1_RESPONSE_EARLY
0.00156 0.11440 0.00462 0.02649 0.11718 0.05191AMIT_DELAYED_EARLY_GENES
0.00006 0.00029 0.00001 0.00318 0.01593 0.18333MAHADEVAN_RESPONSE_TO_MP470_UP
0.11477 0.00000 0.00000 0.17152 0.00464 0.12023SMID_BREAST_CANCER_NORMAL_LIKE_UP
0.00001 0.00358 0.00151 0.05376 0.14412 0.03916HINATA_NFKB_TARGETS_FIBROBLAST_UP