BICLUSTER_ID : UPREG-280
PATHOGENS /4/ : pseudomonas aeruginosa,escherichia coli,mycobacterium tuberculosis,helicobacter pylori
TARGETS /6/ : IL6, CCL20, PTGS2, GCH1, ICAM1, CCL2
Gene SetLeading Edge Genes
NETPATH IL 1 PATHWAY UPBIRC3, CCL20, CXCL1, CCL2, TNFAIP6, JMJD3, NFKBIA, IL6, PTGS2, ICAM1, CXCL2, SOD2
GERY CEBP TARGETSCXCL1, GCH1, EREG
NOJIMA SFRP2 TARGETS UP
NCI TCRCALCIUMPATHWAY
CORUM IKBA-NFKAPPABP65-NFKAPPABP50 COMPLEX
CORUM NFKB1-NFKB2-RELA-RELB COMPLEX
ONDER CDH1 TARGETS 3 DN
BIOCARTA STEM PATHWAY
DAUER STAT3 TARGETS UP
NETPATH IL 9 PATHWAY UP
MAHAJAN RESPONSE TO IL1A UP
BIOCARTA EPONFKB PATHWAY
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
NETPATH IL 6 PATHWAY UPMAFF, CXCL1, CEBPB, BCL3
MENSE HYPOXIA UP
CHEN HOXA5 TARGETS 9HR UP
LINDSTEDT DENDRITIC CELL MATURATION B
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
NCI NFKAPPABALTERNATIVEPATHWAY
ELVIDGE HYPOXIA UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
XU HGF TARGETS REPRESSED BY AKT1 UP
GESERICK TERT TARGETS DN
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 5
BROWNE HCMV INFECTION 2HR UP
MAHADEVAN RESPONSE TO MP470 DN
HARRIS HYPOXIA
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
HINATA NFKB TARGETS KERATINOCYTE UP
KOBAYASHI EGFR SIGNALING 6HR DN
AMIT EGF RESPONSE 20 HELA
DAZARD UV RESPONSE CLUSTER G3
ST TUMOR NECROSIS FACTOR PATHWAYNFKBIA, BIRC3, NFKB2, TNFAIP3
ELVIDGE HYPOXIA BY DMOG UP
NAGASHIMA NRG1 SIGNALING UP
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
GILMORE CORE NFKB PATHWAY
DUTTA APOPTOSIS VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
CORUM NFKB1-NFKB2-REL-RELA-RELB COMPLEX
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
CORUM IKAPPABALPHA-NFKAPPABP50-NFKAPPABP65 COMPLEX
PRAMOONJAGO SOX4 TARGETS UP
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx2 npgechelicobacter pylori kx1 mgeppseudomonas aeruginosamycobacterium tuberculosishelicobacter pylori kx2 mgepescherichia coliGeneSet Name
0.08273 0.00000 0.00004 0.00602 0.00000 0.00000NETPATH_IL_1_PATHWAY_UP
0.14043 0.00133 0.00843 0.00000 0.00038 0.01389GERY_CEBP_TARGETS
0.03559 0.00032 0.06631 0.00000 0.00000 0.00018NOJIMA_SFRP2_TARGETS_UP
0.14999 0.17276 0.12883 0.04081 0.15099 0.00732NCI_TCRCALCIUMPATHWAY
0.11378 0.07068 0.10409 0.08924 0.06000 0.05482CORUM_IKBA-NFKAPPABP65-NFKAPPABP50_COMPLEX
0.04955 0.02900 0.03519 0.04157 0.01452 0.01451CORUM_NFKB1-NFKB2-RELA-RELB_COMPLEX
0.07857 0.00085 0.00003 0.10086 0.00020 0.00000ONDER_CDH1_TARGETS_3_DN
0.08374 0.02542 0.17647 0.14979 0.00925 0.00008BIOCARTA_STEM_PATHWAY
0.04938 0.00067 0.00006 0.00000 0.00008 0.00003DAUER_STAT3_TARGETS_UP
0.03276 0.00013 0.06627 0.08229 0.00202 0.00028NETPATH_IL_9_PATHWAY_UP
0.05579 0.00517 0.00000 0.00132 0.00001 0.00000MAHAJAN_RESPONSE_TO_IL1A_UP
0.03513 0.00105 0.00600 0.00738 0.00246 0.00507BIOCARTA_EPONFKB_PATHWAY
0.11321 0.01988 0.00593 0.02002 0.00622 0.00438NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.13630 0.00236 0.01244 0.00000 0.01969 0.00000NETPATH_IL_6_PATHWAY_UP
0.01619 0.00855 0.10399 0.00000 0.00036 0.09188MENSE_HYPOXIA_UP
0.09671 0.00000 0.00776 0.00006 0.00000 0.00050CHEN_HOXA5_TARGETS_9HR_UP
0.00320 0.00000 0.00005 0.00000 0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00000 0.00000 0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00011 0.00002 0.00036 0.00000 0.00000 0.00000GAURNIER_PSMD4_TARGETS
0.00009 0.02162 0.05448 0.00869 0.04760 0.03683NCI_NFKAPPABALTERNATIVEPATHWAY
0.09761 0.00083 0.10177 0.00052 0.00095 0.01124ELVIDGE_HYPOXIA_UP
0.08415 0.00937 0.00000 0.00000 0.00677 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.01844 0.00000 0.00000 0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.05769 0.00293 0.00802 0.00217 0.01339 0.00026IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.15627 0.07397 0.10004 0.06625 0.05676 0.00330XU_HGF_TARGETS_REPRESSED_BY_AKT1_UP
0.01236 0.00257 0.00178 0.00002 0.00002 0.00083GESERICK_TERT_TARGETS_DN
0.14330 0.00012 0.00150 0.05325 0.00313 0.03327YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5
0.03942 0.00034 0.00000 0.00000 0.00890 0.00014BROWNE_HCMV_INFECTION_2HR_UP
0.09615 0.00340 0.00187 0.00000 0.00005 0.00317MAHADEVAN_RESPONSE_TO_MP470_DN
0.01945 0.00027 0.00391 0.00067 0.00009 0.00034HARRIS_HYPOXIA
0.03267 0.00000 0.00002 0.00000 0.00000 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.16190 0.00002 0.00000 0.00000 0.00000 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.10019 0.00064 0.00269 0.00020 0.00002 0.00015KOBAYASHI_EGFR_SIGNALING_6HR_DN
0.11482 0.02197 0.00091 0.00486 0.00435 0.00089AMIT_EGF_RESPONSE_20_HELA
0.19060 0.06558 0.00321 0.02412 0.01539 0.00510DAZARD_UV_RESPONSE_CLUSTER_G3
0.02351 0.00032 0.00000 0.00010 0.00008 0.00026ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.05588 0.00023 0.03582 0.00043 0.00024 0.01098ELVIDGE_HYPOXIA_BY_DMOG_UP
0.08878 0.00000 0.00113 0.00000 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.01521 0.00011 0.00251 0.02521 0.00002 0.00037SOUCEK_MYC_TARGETS
0.00000 0.00000 0.00000 0.00000 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.01817 0.00003 0.00340 0.00092 0.00000 0.00003GILMORE_CORE_NFKB_PATHWAY
0.03297 0.00000 0.00086 0.00002 0.00000 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.01942 0.00000 0.00000 0.00002 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.06149 0.00719 0.06462 0.05523 0.00445 0.00288CORUM_NFKB1-NFKB2-REL-RELA-RELB_COMPLEX
0.03486 0.00723 0.00002 0.00039 0.00076 0.00000ZUCCHI_METASTASIS_DN
0.01745 0.00000 0.00102 0.00000 0.00000 0.00003NAGASHIMA_EGF_SIGNALING_UP
0.14826 0.00157 0.00000 0.00000 0.00124 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00810 0.00002 0.00009 0.00004 0.00001 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.10091 0.06039 0.11737 0.08863 0.06654 0.04958CORUM_IKAPPABALPHA-NFKAPPABP50-NFKAPPABP65_COMPLEX
0.00069 0.00000 0.00151 0.00000 0.00000 0.00005PRAMOONJAGO_SOX4_TARGETS_UP
0.10685 0.00000 0.00000 0.00000 0.00009 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.03534 0.00002 0.00367 0.00004 0.00000 0.00000AMIT_EGF_RESPONSE_60_MCF10A
0.00042 0.00018 0.00003 0.00176 0.00000 0.00000REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES