BICLUSTER_ID : UPREG-292
PATHOGENS /6/ : brucella neotomae,listeria monocytogenes,escherichia coli,aeromonas caviae,brucella melitensis,ehrlichia chaffeensis
TARGETS /2/ : IL1B, TNF
Gene SetLeading Edge Genes
NCI IL23PATHWAYSOCS3, NFKBIA, IL1B, TNF
NETPATH IL 3 PATHWAY UPSOCS3, IL1B, MYC, CCL4
NETPATH IL 4 PATHWAY DOWNNFKBIA, TNF, GBP2
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
BENNETT SYSTEMIC LUPUS ERYTHEMATOSUS
BIOCARTA PML PATHWAY
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NETPATH IL 6 PATHWAY UPSOCS3
MCLACHLAN DENTAL CARIES UP
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN
LINDSTEDT DENDRITIC CELL MATURATION B
SA MMP CYTOKINE CONNECTION
NETPATH IL 5 PATHWAY UP
FOSTER INFLAMMATORY RESPONSE LPS DN
MCLACHLAN DENTAL CARIES DN
KEGG ALLOGRAFT REJECTION
LINDSTEDT DENDRITIC CELL MATURATION A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
RADAEVA RESPONSE TO IFNA1 UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHOU INFLAMMATORY RESPONSE LPS UP
BOWIE RESPONSE TO EXTRACELLULAR MATRIX
NETPATH IL 7 PATHWAY UP
SANA TNF SIGNALING UP
MOSERLE IFNA RESPONSE
FOSTER INFLAMMATORY RESPONSE LPS UP
LEE LIVER CANCER MYC E2F1 UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP
VERHAAK AML WITH NPM1 MUTATED UP
DER IFN BETA RESPONSE UP
GEISS RESPONSE TO DSRNA UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
HINATA NFKB TARGETS KERATINOCYTE UP
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1
BASSO CD40 SIGNALING UP
HESS TARGETS OF HOXA9 AND MEIS1 DN
SOUCEK MYC TARGETS
HUMMEL BURKITTS LYMPHOMA DN
ZHU CMV ALL UP
KEGG SYSTEMIC LUPUS ERYTHEMATOSUS
DUTTA APOPTOSIS VIA NFKB
NETPATH IL 2 PATHWAY UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
DIRMEIER LMP1 RESPONSE EARLY
DER IFN GAMMA RESPONSE UP
MAHADEVAN RESPONSE TO MP470 UP
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
ehrlichia chaffeensis arkansabrucella melitensislisteria monocytogenesbrucella neotomaeaeromonas caviaescherichia coliGeneSet Name
0.00000 0.03782 0.00100 0.04130 0.00704 0.00000NCI_IL23PATHWAY
0.00000 0.00052 0.00553 0.00000 0.00216 0.00000NETPATH_IL_3_PATHWAY_UP
0.00001 0.00471 0.00001 0.00269 0.01190 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.00000 0.10177 0.02915 0.17773 0.01697 0.00000KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00000 0.19040 0.00000 0.07917 0.00041 0.00000BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS
0.01308 0.13810 0.00624 0.06127 0.12171 0.01149BIOCARTA_PML_PATHWAY
0.00021 0.03113 0.00023 0.03682 0.01924 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.01097 0.00563 0.00016 0.00155 0.05120 0.00003DAUER_STAT3_TARGETS_UP
0.00001 0.18585 0.00001 0.01035 0.00001 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.00003 0.00163 0.00233 0.01660 0.10211 0.00000NETPATH_IL_6_PATHWAY_UP
0.00000 0.01108 0.00000 0.00479 0.00003 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.00000 0.03772 0.00001 0.00537 0.00000 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.02780 0.00728 0.00306 0.00660 0.03029 0.09136PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN
0.00007 0.01411 0.00437 0.02410 0.00053 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00037 0.04554 0.04438 0.10715 0.02492 0.00133SA_MMP_CYTOKINE_CONNECTION
0.00007 0.01177 0.00007 0.12369 0.07327 0.00001NETPATH_IL_5_PATHWAY_UP
0.00000 0.00031 0.00001 0.00621 0.00001 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.01946 0.00000 0.00595 0.00003 0.00002MCLACHLAN_DENTAL_CARIES_DN
0.00009 0.09553 0.00001 0.14303 0.01652 0.00000KEGG_ALLOGRAFT_REJECTION
0.00000 0.00644 0.00000 0.00010 0.00124 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00000 0.00010 0.00000 0.00041 0.00002 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00642 0.00001 0.00119 0.00001 0.00000GAURNIER_PSMD4_TARGETS
0.00000 0.09499 0.00000 0.14758 0.00000 0.00000RADAEVA_RESPONSE_TO_IFNA1_UP
0.00000 0.00017 0.00000 0.00387 0.00001 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00269 0.02743 0.00000 0.02297 0.01590 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00254 0.18600 0.00007 0.17499 0.00058 0.00001BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX
0.00034 0.02550 0.09197 0.01290 0.16616 0.00000NETPATH_IL_7_PATHWAY_UP
0.00000 0.00362 0.00000 0.00058 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.00000 0.10219 0.00000 0.02846 0.00000 0.00000MOSERLE_IFNA_RESPONSE
0.00000 0.09817 0.00000 0.09836 0.01920 0.00011FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.14130 0.02477 0.14464 0.01790 0.08000LEE_LIVER_CANCER_MYC_E2F1_UP
0.00000 0.06677 0.00000 0.02175 0.00000 0.00000TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP
0.00000 0.01897 0.00000 0.03242 0.08932 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00030 0.03901 0.00000 0.05335 0.00003 0.00000DER_IFN_BETA_RESPONSE_UP
0.00175 0.09792 0.00027 0.01183 0.00364 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.01044 0.05929 0.00588 0.00835 0.00700 0.00000KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00055 0.05127 0.00001 0.09086 0.06206 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00221 0.13111 0.07166 0.11004 0.08380 0.00653SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1
0.00000 0.04270 0.00020 0.03927 0.00110 0.00000BASSO_CD40_SIGNALING_UP
0.00000 0.14126 0.00001 0.15914 0.01035 0.08966HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00003 0.00824 0.09270 0.01093 0.00169 0.00037SOUCEK_MYC_TARGETS
0.00212 0.05051 0.17259 0.07619 0.11042 0.00005HUMMEL_BURKITTS_LYMPHOMA_DN
0.00053 0.10116 0.00000 0.00066 0.14609 0.00000ZHU_CMV_ALL_UP
0.01775 0.07780 0.00001 0.01173 0.00199 0.08323KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS
0.00000 0.00246 0.01422 0.00644 0.05340 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.00029 0.03203 0.00068 0.17779 0.07215 0.00000NETPATH_IL_2_PATHWAY_UP
0.00001 0.00050 0.00001 0.00010 0.09323 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.00015 0.00199 0.00214 0.00564 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00007 0.02211 0.00068 0.08485 0.00005 0.00000DER_IFN_GAMMA_RESPONSE_UP
0.00029 0.15514 0.00004 0.09849 0.00240 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.00001 0.04288 0.00001 0.00947 0.00003 0.00000SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP