BICLUSTER_ID : UPREG-294
PATHOGENS /3/ : pseudomonas aeruginosa,yersinia enterocolitica,burkholderia pseudomallei
TARGETS /3/ : CCL20, PTGS2, CCL2
Gene SetLeading Edge Genes
NETPATH IL 4 PATHWAY DOWNCCL20, PTGS2, CDKN1A, CCL2, CXCL2
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
MISSIAGLIA REGULATED BY METHYLATION UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
MAHAJAN RESPONSE TO IL1A UP
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS
DORN ADENOVIRUS INFECTION 32HR DN
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
CROONQUIST STROMAL STIMULATION UP
REACTOME PHASE 1 FUNCTIONALIZATION
RASHI RESPONSE TO IONIZING RADIATION 2
HALMOS CEBPA TARGETS UP
LINDSTEDT DENDRITIC CELL MATURATION A
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL UP
SAGIV CD24 TARGETS DN
ELVIDGE HYPOXIA UP
HORIUCHI WTAP TARGETS UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
NETPATH IL 7 PATHWAY UPCXCL1, CXCL2
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 5
ZHONG RESPONSE TO AZACITIDINE AND TSA UP
MAHADEVAN RESPONSE TO MP470 DN
JEON SMAD6 TARGETS UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
HARRIS HYPOXIA
CONRAD GERMLINE STEM CELL
TURASHVILI BREAST DUCTAL CARCINOMA VS DUCTAL NORMAL DN
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION SUSTAINDED IN ERYTHROCYTE UP
BOYAULT LIVER CANCER SUBCLASS G56 DN
HINATA NFKB TARGETS KERATINOCYTE UP
BIOCARTA CYTOKINE PATHWAY
SEIKE LUNG CANCER POOR SURVIVAL
DORN ADENOVIRUS INFECTION 48HR DN
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D DN
OSADA ASCL1 TARGETS DN
VART KSHV INFECTION ANGIOGENIC MARKERS UP
AMIT SERUM RESPONSE 60 MCF10A
NAGASHIMA NRG1 SIGNALING UP
SOUCEK MYC TARGETS
DUTTA APOPTOSIS VIA NFKB
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
ZERBINI RESPONSE TO SULINDAC UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS MAGENTA UP
CROMER TUMORIGENESIS UP
SABATES COLORECTAL ADENOMA UP
DIRMEIER LMP1 RESPONSE EARLY
WOTTON RUNX TARGETS UP
MAHADEVAN RESPONSE TO MP470 UP
FERRARI RESPONSE TO FENRETINIDE UP
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
BILD HRAS ONCOGENIC SIGNATURE
ZHOU INFLAMMATORY RESPONSE LIVE UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP
ONDER CDH1 TARGETS 3 DN
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
HELLEBREKERS SILENCED DURING TUMOR ANGIOGENESIS
MENSE HYPOXIA UP
NEWMAN ERCC6 TARGETS UP
PODAR RESPONSE TO ADAPHOSTIN UP
BERENJENO TRANSFORMED BY RHOA FOREVER DN
DAZARD UV RESPONSE CLUSTER G2
CHEN HOXA5 TARGETS 9HR UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
CORUM ABIN2-NFKB1-MAP3K8 COMPLEX
TAVOR CEBPA TARGETS UP
SEKI INFLAMMATORY RESPONSE LPS UP
OSAWA TNF TARGETS
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZEMBUTSU SENSITIVITY TO MITOMYCIN
SENESE HDAC1 AND HDAC2 TARGETS UP
AMIT SERUM RESPONSE 120 MCF10A
BROWNE HCMV INFECTION 2HR UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
KIM WT1 TARGETS UP
VERHAAK AML WITH NPM1 MUTATED UP
GEISS RESPONSE TO DSRNA UP
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
XU HGF SIGNALING NOT VIA AKT1 6HR
KOBAYASHI EGFR SIGNALING 6HR DN
GERY CEBP TARGETSATF3, IFRD1, CXCL1, KLF4, DUSP1, PTX3
ZHOU INFLAMMATORY RESPONSE FIMA UP
DASU IL6 SIGNALING UP
ELVIDGE HYPOXIA BY DMOG UP
AMIT EGF RESPONSE 120 MCF10A
TIAN TNF SIGNALING VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
NAGASHIMA EGF SIGNALING UP
AMIT DELAYED EARLY GENES
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
burkholderia pseudomalleiyersinia enterocolitica p60 bcpseudomonas aeruginosa fdr440GeneSet Name
0.16712 0.00040 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.02392 0.00000 0.00195KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00964 0.00145 0.00000MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.01050 0.00000 0.00010OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.13459 0.00508 0.01991SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.00002 0.00000 0.01700GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.01913 0.00009 0.00044MAHAJAN_RESPONSE_TO_IL1A_UP
0.09854 0.00417 0.17577REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS
0.19819 0.00471 0.00021DORN_ADENOVIRUS_INFECTION_32HR_DN
0.05958 0.00005 0.02145REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.02367 0.01017 0.00017CROONQUIST_STROMAL_STIMULATION_UP
0.02868 0.11649 0.11318REACTOME_PHASE_1_FUNCTIONALIZATION
0.16626 0.00008 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.11122 0.00037 0.00031HALMOS_CEBPA_TARGETS_UP
0.00750 0.00000 0.00003LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.09910 0.00171 0.00347LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP
0.00252 0.07586 0.00091SAGIV_CD24_TARGETS_DN
0.02727 0.00036 0.16459ELVIDGE_HYPOXIA_UP
0.03425 0.00038 0.00881HORIUCHI_WTAP_TARGETS_UP
0.09871 0.00492 0.00064IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00290 0.00031 0.15015AMIT_EGF_RESPONSE_40_HELA
0.16021 0.00028 0.00003NETPATH_IL_7_PATHWAY_UP
0.03172 0.14881 0.06558YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5
0.10875 0.09717 0.00816ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP
0.00025 0.00009 0.02760MAHADEVAN_RESPONSE_TO_MP470_DN
0.01183 0.03022 0.00005JEON_SMAD6_TARGETS_UP
0.12979 0.00000 0.00052THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.16949 0.00029 0.00003HARRIS_HYPOXIA
0.03722 0.14859 0.08773CONRAD_GERMLINE_STEM_CELL
0.03622 0.02618 0.00130TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN
0.16014 0.00729 0.06129TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP
0.00734 0.14873 0.00799BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN
0.00143 0.00000 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.13358 0.00047 0.00347BIOCARTA_CYTOKINE_PATHWAY
0.10886 0.01385 0.00573SEIKE_LUNG_CANCER_POOR_SURVIVAL
0.14963 0.00630 0.00037DORN_ADENOVIRUS_INFECTION_48HR_DN
0.01777 0.00020 0.13279TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN
0.01311 0.06140 0.11392OSADA_ASCL1_TARGETS_DN
0.07425 0.00016 0.08419VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP
0.00292 0.00000 0.01060AMIT_SERUM_RESPONSE_60_MCF10A
0.00002 0.00000 0.00002NAGASHIMA_NRG1_SIGNALING_UP
0.03675 0.00008 0.02994SOUCEK_MYC_TARGETS
0.07914 0.00013 0.00513DUTTA_APOPTOSIS_VIA_NFKB
0.05436 0.00004 0.06809TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.11717 0.12784 0.03840ZERBINI_RESPONSE_TO_SULINDAC_UP
0.00142 0.01191 0.04178GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP
0.04511 0.00013 0.01404CROMER_TUMORIGENESIS_UP
0.04328 0.02321 0.00157SABATES_COLORECTAL_ADENOMA_UP
0.04849 0.00000 0.00002DIRMEIER_LMP1_RESPONSE_EARLY
0.19046 0.05037 0.15097WOTTON_RUNX_TARGETS_UP
0.14983 0.00000 0.00002MAHADEVAN_RESPONSE_TO_MP470_UP
0.05896 0.00050 0.00002FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.10469 0.00000 0.00009REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.01123 0.00000 0.00028BILD_HRAS_ONCOGENIC_SIGNATURE
0.00909 0.00000 0.00010ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.00000 0.00020 0.02769GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP
0.05647 0.00099 0.00194ONDER_CDH1_TARGETS_3_DN
0.00027 0.00004 0.00068AMIT_EGF_RESPONSE_120_HELA
0.00256 0.02597 0.00085DAUER_STAT3_TARGETS_UP
0.09145 0.00048 0.00016HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS
0.00659 0.06772 0.05632MENSE_HYPOXIA_UP
0.10910 0.03715 0.03524NEWMAN_ERCC6_TARGETS_UP
0.00000 0.00001 0.13382PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.00758 0.00060 0.11486BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.02586 0.01385 0.00228DAZARD_UV_RESPONSE_CLUSTER_G2
0.03571 0.00074 0.00550CHEN_HOXA5_TARGETS_9HR_UP
0.00017 0.00001 0.12253GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.16683 0.16475 0.07172CORUM_ABIN2-NFKB1-MAP3K8_COMPLEX
0.08082 0.02930 0.08516TAVOR_CEBPA_TARGETS_UP
0.01261 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.03652 0.13046 0.00149OSAWA_TNF_TARGETS
0.00000 0.00030 0.00002GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00226 0.03175CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.00209 0.11465 0.01084SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.00139 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.02612 0.08342 0.04728ZEMBUTSU_SENSITIVITY_TO_MITOMYCIN
0.10073 0.00026 0.00002SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.02599 0.00000 0.02960AMIT_SERUM_RESPONSE_120_MCF10A
0.05164 0.00673 0.00002BROWNE_HCMV_INFECTION_2HR_UP
0.00000 0.00006 0.00011HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00000 0.00270 0.02538SESTO_RESPONSE_TO_UV_C3
0.05021 0.00000 0.00002KIM_WT1_TARGETS_UP
0.13600 0.00000 0.00218VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.11502 0.00000 0.00007GEISS_RESPONSE_TO_DSRNA_UP
0.00009 0.00007 0.03950GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.00019 0.00000 0.02749UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00980 0.02133 0.00558XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR
0.01348 0.11776 0.00005KOBAYASHI_EGFR_SIGNALING_6HR_DN
0.00015 0.00510 0.00131GERY_CEBP_TARGETS
0.00000 0.00000 0.00013ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.03694 0.00020 0.00711DASU_IL6_SIGNALING_UP
0.03396 0.00017 0.15685ELVIDGE_HYPOXIA_BY_DMOG_UP
0.05040 0.00028 0.00020AMIT_EGF_RESPONSE_120_MCF10A
0.00000 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.00000 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.02880 0.00000 0.00011OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00000 0.00000 0.00002NAGASHIMA_EGF_SIGNALING_UP
0.00501 0.04380 0.04277AMIT_DELAYED_EARLY_GENES
0.01688 0.00119 0.00044PRAMOONJAGO_SOX4_TARGETS_UP
0.09787 0.00000 0.06556PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.03538 0.00008 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00375 0.00000 0.00027AMIT_EGF_RESPONSE_60_MCF10A