BICLUSTER_ID : UPREG-314
PATHOGENS /7/ : brucella neotomae,listeria monocytogenes,bifidobacterium bifidum,streptococcus pneumoniae,mycobacterium tuberculosis,helicobacter pylori,ehrlichia chaffeensis
TARGETS /2/ : IL6, PTGS2
Gene SetLeading Edge Genes
NETPATH IL 1 PATHWAY UPIL6, PTGS2, CXCL2
ONDER CDH1 TARGETS 3 DN
LEONARD HYPOXIA
DAUER STAT3 TARGETS UP
MAHAJAN RESPONSE TO IL1A UP
REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G
NETPATH IL 6 PATHWAY UPGADD45B
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN
CHEN HOXA5 TARGETS 9HR UP
LINDSTEDT DENDRITIC CELL MATURATION B
NCI HOST INTERACTIONS OF HIV FACTORS
SEKI INFLAMMATORY RESPONSE LPS UP
REACTOME P53 INDEPENDENT DNA DAMAGE RESPONSE
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ELVIDGE HYPOXIA UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
MAHADEVAN RESPONSE TO MP470 DN
REACTOME STABILIZATION OF P53
NCI REGULATION OF ORNITHINE DECARBOXYLASE ODC
REACTOME REGULATION OF ORNITHINE DECARBOXYLASE
HARRIS HYPOXIA
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
HINATA NFKB TARGETS KERATINOCYTE UP
GERY CEBP TARGETS
ELVIDGE HYPOXIA BY DMOG UP
TIAN TNF SIGNALING VIA NFKB
SOUCEK MYC TARGETS
NAGASHIMA NRG1 SIGNALING UP
DUTTA APOPTOSIS VIA NFKB
NCI SCF BETA TRCP MEDIATED DEGRADATION OF EMI1
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
KEGG PROTEASOME
NCI REGULATION OF ACTIVATED PAK 2P34 BY PROTEASOME MEDIATED DEGRADATION
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
NCI UBIQUITIN MEDIATED DEGRADATION OF PHOSPHORYLATED CDC25A
DIRMEIER LMP1 RESPONSE EARLY
PRAMOONJAGO SOX4 TARGETS UP
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx2 npgecehrlichia chaffeensis arkansastreptococcus pneumoniae g54listeria monocytogenesbifidobacterium bifidummycobacterium tuberculosisbrucella neotomaeGeneSet Name
0.08273 0.00744 0.02186 0.00000 0.00007 0.00602 0.00114NETPATH_IL_1_PATHWAY_UP
0.07857 0.02809 0.03102 0.00011 0.01033 0.10086 0.01819ONDER_CDH1_TARGETS_3_DN
0.00289 0.01232 0.00548 0.00328 0.00822 0.01105 0.16786LEONARD_HYPOXIA
0.04938 0.01097 0.03237 0.00016 0.00011 0.00000 0.00155DAUER_STAT3_TARGETS_UP
0.05579 0.01198 0.08911 0.00046 0.00474 0.00132 0.16767MAHAJAN_RESPONSE_TO_IL1A_UP
0.00000 0.06904 0.05320 0.00069 0.14766 0.00468 0.00129REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G
0.13630 0.00003 0.01842 0.00233 0.00007 0.00000 0.01660NETPATH_IL_6_PATHWAY_UP
0.11321 0.01021 0.13119 0.01127 0.04736 0.02002 0.19381NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.00000 0.02780 0.04093 0.00306 0.11301 0.00008 0.00660PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN
0.09671 0.01709 0.00050 0.00000 0.07447 0.00006 0.02011CHEN_HOXA5_TARGETS_9HR_UP
0.00320 0.00007 0.00817 0.00437 0.00000 0.00000 0.02410LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00000 0.03268 0.04816 0.00045 0.04307 0.00787 0.00221NCI_HOST_INTERACTIONS_OF_HIV_FACTORS
0.00000 0.00000 0.02093 0.00000 0.00000 0.00000 0.00041SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.03913 0.05824 0.00031 0.11407 0.01493 0.00150REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE
0.08415 0.00007 0.11160 0.00097 0.00000 0.00000 0.07552GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.09761 0.01170 0.00034 0.00023 0.02232 0.00052 0.04424ELVIDGE_HYPOXIA_UP
0.01844 0.00000 0.00231 0.00000 0.00000 0.00000 0.00387ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.09615 0.18500 0.15502 0.01146 0.00016 0.00000 0.00665MAHADEVAN_RESPONSE_TO_MP470_DN
0.00000 0.05325 0.13021 0.00163 0.15123 0.00975 0.00387REACTOME_STABILIZATION_OF_P53
0.00000 0.01628 0.05117 0.00061 0.04850 0.02665 0.00259NCI_REGULATION_OF_ORNITHINE_DECARBOXYLASE__ODC_
0.00000 0.02844 0.11131 0.00069 0.10685 0.02161 0.00938REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE
0.01945 0.00160 0.10031 0.00000 0.05400 0.00067 0.17495HARRIS_HYPOXIA
0.03267 0.02814 0.00000 0.00007 0.08234 0.00000 0.00256UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.16190 0.00055 0.00568 0.00001 0.00013 0.00000 0.09086HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.14043 0.01308 0.12493 0.00163 0.00008 0.00000 0.18522GERY_CEBP_TARGETS
0.05588 0.04510 0.00018 0.00142 0.00784 0.00043 0.11243ELVIDGE_HYPOXIA_BY_DMOG_UP
0.00000 0.00003 0.16057 0.00054 0.00000 0.00000 0.05899TIAN_TNF_SIGNALING_VIA_NFKB
0.01521 0.00003 0.08229 0.09270 0.00012 0.02521 0.01093SOUCEK_MYC_TARGETS
0.08878 0.00648 0.00022 0.00045 0.05507 0.00000 0.06679NAGASHIMA_NRG1_SIGNALING_UP
0.03297 0.00000 0.05455 0.01422 0.00215 0.00002 0.00644DUTTA_APOPTOSIS_VIA_NFKB
0.00000 0.07201 0.03767 0.00045 0.04677 0.00570 0.00384NCI_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1
0.01942 0.00001 0.03864 0.00001 0.00000 0.00002 0.00010GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.03642 0.05741 0.00038 0.19567 0.00367 0.00158KEGG_PROTEASOME
0.00000 0.02962 0.04796 0.00056 0.04561 0.00636 0.00221NCI_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION
0.03486 0.10538 0.01824 0.00518 0.03751 0.00039 0.01371ZUCCHI_METASTASIS_DN
0.01745 0.00040 0.00045 0.00001 0.09324 0.00000 0.01336NAGASHIMA_EGF_SIGNALING_UP
0.00000 0.04449 0.04458 0.00046 0.04750 0.01224 0.00234NCI_UBIQUITIN_MEDIATED_DEGRADATION_OF_PHOSPHORYLATED_CDC25A
0.14826 0.00000 0.08905 0.00199 0.00294 0.00000 0.00214DIRMEIER_LMP1_RESPONSE_EARLY
0.00069 0.07569 0.00000 0.01526 0.00000 0.00000 0.10655PRAMOONJAGO_SOX4_TARGETS_UP
0.03534 0.02646 0.00090 0.01523 0.00467 0.00004 0.02489AMIT_EGF_RESPONSE_60_MCF10A