BICLUSTER_ID : UPREG-322
PATHOGENS /3/ : listeria monocytogenes,yersinia enterocolitica,helicobacter pylori
TARGETS /3/ : CSF2RA, TNFRSF1B, TNF
Gene SetLeading Edge Genes
NETPATH IL 3 PATHWAY UPSOCS3, CSF2RA, TNF, CCR1
NETPATH IL 2 PATHWAY UPSOCS3, IL18R1, TNFRSF1B, PTPRC, TNF
NETPATH IL 4 PATHWAY DOWNCXCL2, TNF
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
RHEIN ALL GLUCOCORTICOID THERAPY UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
LINDGREN BLADDER CANCER CLUSTER 2B
KEGG GRAFT VERSUS HOST DISEASE
KEGG ASTHMA
AUJLA IL22 AND IL17A SIGNALING
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
HELLER HDAC TARGETS SILENCED BY METHYLATION DN
SA MMP CYTOKINE CONNECTION
RASHI RESPONSE TO IONIZING RADIATION 2
WALLACE PROSTATE CANCER RACE UP
HORIUCHI WTAP TARGETS UP
WIELAND UP BY HBV INFECTION
NETPATH IL 7 PATHWAY UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D DN
BIOCARTA TH1TH2 PATHWAY
DIRMEIER LMP1 RESPONSE LATE UP
MARKEY RB1 ACUTE LOF UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D DN
BASSO CD40 SIGNALING UP
BIOCARTA DC PATHWAY
POOLA INVASIVE BREAST CANCER UP
MAHADEVAN RESPONSE TO MP470 UP
LIU VAV3 PROSTATE CARCINOGENESIS UP
KEGG AUTOIMMUNE THYROID DISEASE
FERRARI RESPONSE TO FENRETINIDE UP
CADWELL ATG16L1 TARGETS UP
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP
LIAN LIPA TARGETS 6M
MCLACHLAN DENTAL CARIES UP
JAATINEN HEMATOPOIETIC STEM CELL DN
NETPATH IL 5 PATHWAY UP
MCLACHLAN DENTAL CARIES DN
KEGG ALLOGRAFT REJECTION
AMIT SERUM RESPONSE 40 MCF10A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
HELLER SILENCED BY METHYLATION UP
FARMER BREAST CANCER CLUSTER 1
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ICHIBA GRAFT VERSUS HOST DISEASE 35D UP
NCI AMB2 NEUTROPHILS PATHWAY
SMID BREAST CANCER LUMINAL B DN
SANA TNF SIGNALING UP
FOSTER INFLAMMATORY RESPONSE LPS UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D DN
BROWNE HCMV INFECTION 2HR UP
STEARMAN LUNG CANCER EARLY VS LATE DN
KEGG HEMATOPOIETIC CELL LINEAGE
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 2
VERHAAK AML WITH NPM1 MUTATED UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION HSC DN
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
NCI IL12 STAT4PATHWAY
NCI IL12 2PATHWAY
TIAN TNF SIGNALING VIA NFKB
GAL LEUKEMIC STEM CELL DN
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LU IL4 SIGNALING
RUTELLA RESPONSE TO HGF UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bl6yersinia enterocolitica wap bclisteria monocytogeneshelicobacter pyloriGeneSet Name
0.00000 0.00000 0.00553 0.15967NETPATH_IL_3_PATHWAY_UP
0.01769 0.00010 0.00068 0.02714NETPATH_IL_2_PATHWAY_UP
0.00145 0.00024 0.00001 0.00844NETPATH_IL_4_PATHWAY_DOWN
0.00000 0.00001 0.02915 0.01320KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.07223 0.04368 0.00045 0.17130RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP
0.00000 0.00000 0.00001 0.06395OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.00000 0.00000 0.00023 0.01575GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.02833 0.00193 0.06578 0.16246LINDGREN_BLADDER_CANCER_CLUSTER_2B
0.00424 0.00024 0.00003 0.16793KEGG_GRAFT_VERSUS_HOST_DISEASE
0.00196 0.04376 0.00022 0.13902KEGG_ASTHMA
0.01525 0.01777 0.00510 0.12378AUJLA_IL22_AND_IL17A_SIGNALING
0.00000 0.00000 0.00001 0.01211ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.07549 0.00970 0.07889 0.19971HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN
0.00406 0.00860 0.04438 0.01625SA_MMP_CYTOKINE_CONNECTION
0.00427 0.00001 0.04054 0.15090RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00001 0.00000 0.00031 0.00000WALLACE_PROSTATE_CANCER_RACE_UP
0.00735 0.00023 0.01805 0.13802HORIUCHI_WTAP_TARGETS_UP
0.18523 0.01379 0.00000 0.00139WIELAND_UP_BY_HBV_INFECTION
0.00623 0.00052 0.09197 0.06443NETPATH_IL_7_PATHWAY_UP
0.00367 0.00057 0.01807 0.05510TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN
0.09631 0.07845 0.02563 0.04641BIOCARTA_TH1TH2_PATHWAY
0.15215 0.00001 0.12444 0.10819DIRMEIER_LMP1_RESPONSE_LATE_UP
0.00200 0.00001 0.00004 0.03172MARKEY_RB1_ACUTE_LOF_UP
0.00195 0.00004 0.00061 0.13511TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN
0.00000 0.00000 0.00020 0.00046BASSO_CD40_SIGNALING_UP
0.00606 0.07276 0.00005 0.06449BIOCARTA_DC_PATHWAY
0.05456 0.00162 0.01413 0.00000POOLA_INVASIVE_BREAST_CANCER_UP
0.00025 0.00006 0.00004 0.15994MAHADEVAN_RESPONSE_TO_MP470_UP
0.02669 0.11363 0.01016 0.01222LIU_VAV3_PROSTATE_CARCINOGENESIS_UP
0.01336 0.17971 0.00296 0.05509KEGG_AUTOIMMUNE_THYROID_DISEASE
0.00508 0.00007 0.06128 0.03414FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.02414 0.07506 0.05446 0.06398CADWELL_ATG16L1_TARGETS_UP
0.19163 0.00121 0.00000 0.06401RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
0.03866 0.10223 0.00001 0.13518NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.09112 0.00178 0.01810 0.02703FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP
0.00491 0.00074 0.00075 0.13986LIAN_LIPA_TARGETS_6M
0.00049 0.00000 0.00000 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.00110 0.00069 0.04089 0.00000JAATINEN_HEMATOPOIETIC_STEM_CELL_DN
0.02712 0.00001 0.00007 0.03211NETPATH_IL_5_PATHWAY_UP
0.00078 0.00001 0.00000 0.00000MCLACHLAN_DENTAL_CARIES_DN
0.00363 0.00070 0.00001 0.02721KEGG_ALLOGRAFT_REJECTION
0.00000 0.00000 0.00799 0.17677AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.00000 0.00000 0.00826SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.00001 0.00123GAURNIER_PSMD4_TARGETS
0.00210 0.00040 0.07324 0.00668HELLER_SILENCED_BY_METHYLATION_UP
0.00492 0.01810 0.00001 0.04805FARMER_BREAST_CANCER_CLUSTER_1
0.00810 0.00008 0.00097 0.07962GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00000 0.12811ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00000 0.00008 0.00011 0.00022ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP
0.03531 0.04505 0.18259 0.08456NCI_AMB2_NEUTROPHILS_PATHWAY
0.00087 0.00824 0.12803 0.00142SMID_BREAST_CANCER_LUMINAL_B_DN
0.00017 0.00000 0.00000 0.02871SANA_TNF_SIGNALING_UP
0.00000 0.00000 0.00000 0.03242FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.08400 0.06203 0.00310 0.14547TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN
0.06014 0.02213 0.02059 0.06309BROWNE_HCMV_INFECTION_2HR_UP
0.03498 0.07820 0.11173 0.07230STEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN
0.00000 0.00344 0.01434 0.06394KEGG_HEMATOPOIETIC_CELL_LINEAGE
0.00075 0.05211 0.12933 0.11188SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2
0.00001 0.00000 0.00000 0.19207VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.16791 0.08297 0.04120 0.06219TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN
0.00514 0.00011 0.00032 0.00409GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.18254 0.01624 0.03297 0.12199NCI_IL12_STAT4PATHWAY
0.00709 0.00156 0.04187 0.10271NCI_IL12_2PATHWAY
0.00000 0.00000 0.00054 0.02721TIAN_TNF_SIGNALING_VIA_NFKB
0.19873 0.05127 0.05920 0.02723GAL_LEUKEMIC_STEM_CELL_DN
0.00027 0.00177 0.02242 0.15392KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00000 0.00001 0.05967OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00017 0.00006 0.01517 0.14149LU_IL4_SIGNALING
0.12398 0.00232 0.00007 0.02572RUTELLA_RESPONSE_TO_HGF_UP