BICLUSTER_ID : UPREG-324
PATHOGENS /3/ : streptococcus pneumoniae,lactobacillus acidophilus,helicobacter pylori
TARGETS /4/ : IL6, CCL20, PTGS2, PIM1
Gene SetLeading Edge Genes
NETPATH IL 4 PATHWAY DOWNIL6, CCL20, GADD45B, PTGS2, BCL6, CXCL2
NETPATH IL 1 PATHWAY UPBIRC3, CCL20, LIF, CXCL1, PLK2, IL6, PTGS2, PIM2, PBEF1, CXCL2
NETPATH IL 9 PATHWAY UPJUNB, PIM1, CITED2
NETPATH IL 3 PATHWAY UPPIM1
NETPATH IL 6 PATHWAY UPGADD45B, CXCL1, JUNB, PIM1, MAP3K8
GERY CEBP TARGETSGADD45B, CXCL1, EREG, JUNB, GADD45G, ATF3, PIM1, MAFK
NOJIMA SFRP2 TARGETS UP
MISSIAGLIA REGULATED BY METHYLATION UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
LEONARD HYPOXIA
MAHAJAN RESPONSE TO IL1A UP
LINDSTEDT DENDRITIC CELL MATURATION B
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
ELVIDGE HYPOXIA UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
MAHADEVAN RESPONSE TO MP470 DN
HARRIS HYPOXIA
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
HINATA NFKB TARGETS KERATINOCYTE UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
SOUCEK MYC TARGETS
DUTTA APOPTOSIS VIA NFKB
ZERBINI RESPONSE TO SULINDAC UP
DIRMEIER LMP1 RESPONSE EARLY
DER IFN GAMMA RESPONSE UP
MAHADEVAN RESPONSE TO MP470 UP
FERRARI RESPONSE TO FENRETINIDE UP
BIOCARTA CD40 PATHWAY
BILD HRAS ONCOGENIC SIGNATURE
ONDER CDH1 TARGETS 3 DN
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
BIOCARTA RANKL PATHWAY
MCLACHLAN DENTAL CARIES UP
DAZARD UV RESPONSE CLUSTER G2
CHEN HOXA5 TARGETS 9HR UP
NCI CD40 PATHWAY
AMIT SERUM RESPONSE 40 MCF10A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHOU INFLAMMATORY RESPONSE LPS UP
XU HGF TARGETS INDUCED BY AKT1 6HR
BROWNE HCMV INFECTION 2HR UP
CORUM REL-MAP3K8-RELA-TNIP2-PAPOLA COMPLEX
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
VERHAAK AML WITH NPM1 MUTATED UP
GEISS RESPONSE TO DSRNA UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
STREICHER LSM1 TARGETS UP
BIOCARTA TNFR2 PATHWAY
ST TUMOR NECROSIS FACTOR PATHWAY
ELVIDGE HYPOXIA BY DMOG UP
TIAN TNF SIGNALING VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
ZUCCHI METASTASIS DN
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
AMIT EGF RESPONSE 60 MCF10A
HINATA NFKB TARGETS FIBROBLAST UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx1 mgeplactobacillus acidophilusstreptococcus pneumoniae tigr4helicobacter pylori kx1 npgecGeneSet Name
0.00002 0.00012 0.01938 0.00644NETPATH_IL_4_PATHWAY_DOWN
0.00000 0.00114 0.00001 0.00201NETPATH_IL_1_PATHWAY_UP
0.00013 0.01316 0.05141 0.00667NETPATH_IL_9_PATHWAY_UP
0.03326 0.00372 0.00810 0.05322NETPATH_IL_3_PATHWAY_UP
0.00236 0.00006 0.00000 0.02074NETPATH_IL_6_PATHWAY_UP
0.00133 0.00427 0.00001 0.04422GERY_CEBP_TARGETS
0.00032 0.00685 0.00000 0.01127NOJIMA_SFRP2_TARGETS_UP
0.00725 0.00001 0.05746 0.00255MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.00008 0.00598 0.00000 0.09695OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.03509 0.00008 0.00058 0.18497GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00002 0.05078 0.00001 0.00008LEONARD_HYPOXIA
0.00517 0.00430 0.00006 0.00083MAHAJAN_RESPONSE_TO_IL1A_UP
0.00000 0.00000 0.00796 0.00011LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00000 0.00034 0.00000 0.10813RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00015 0.00000 0.15403 0.00003LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00083 0.10353 0.00000 0.11617ELVIDGE_HYPOXIA_UP
0.00293 0.00648 0.08439 0.00098IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00125 0.00081 0.00000 0.12195AMIT_EGF_RESPONSE_40_HELA
0.08369 0.02475 0.00068 0.09623GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.00340 0.00321 0.00000 0.09518MAHADEVAN_RESPONSE_TO_MP470_DN
0.00027 0.18721 0.00000 0.08612HARRIS_HYPOXIA
0.00015 0.00593 0.00002 0.02451DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.00002 0.00000 0.00741 0.00256HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00005 0.00000 0.02561 0.06948KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00077 0.00000 0.01887 0.12757BASSO_CD40_SIGNALING_UP
0.00011 0.00010 0.02991 0.00009SOUCEK_MYC_TARGETS
0.00000 0.00233 0.00090 0.05736DUTTA_APOPTOSIS_VIA_NFKB
0.00318 0.18728 0.00038 0.06538ZERBINI_RESPONSE_TO_SULINDAC_UP
0.00157 0.00007 0.00000 0.06932DIRMEIER_LMP1_RESPONSE_EARLY
0.03795 0.00091 0.17933 0.00454DER_IFN_GAMMA_RESPONSE_UP
0.00002 0.00272 0.05724 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.00008 0.15133 0.00024 0.11271FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.02889 0.03092 0.06184 0.13504BIOCARTA_CD40_PATHWAY
0.00029 0.00628 0.00000 0.16783BILD_HRAS_ONCOGENIC_SIGNATURE
0.00085 0.00174 0.00000 0.06938ONDER_CDH1_TARGETS_3_DN
0.00067 0.00259 0.00000 0.01934DAUER_STAT3_TARGETS_UP
0.00031 0.00000 0.13850 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.02627 0.00384 0.05739 0.04517BIOCARTA_RANKL_PATHWAY
0.00018 0.00667 0.18322 0.02102MCLACHLAN_DENTAL_CARIES_UP
0.00079 0.06213 0.00000 0.15355DAZARD_UV_RESPONSE_CLUSTER_G2
0.00000 0.04051 0.00003 0.00899CHEN_HOXA5_TARGETS_9HR_UP
0.00012 0.02747 0.11127 0.14335NCI_CD40_PATHWAY
0.00874 0.00031 0.00000 0.13910AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00002 0.00000 0.09452 0.00000GAURNIER_PSMD4_TARGETS
0.00937 0.00000 0.00000 0.00796GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00001 0.00002ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00307 0.00000 0.05005 0.00001ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.04723 0.11695 0.05262 0.01849XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR
0.00034 0.06476 0.00000 0.02678BROWNE_HCMV_INFECTION_2HR_UP
0.12111 0.05982 0.11125 0.05756CORUM_REL-MAP3K8-RELA-TNIP2-PAPOLA_COMPLEX
0.00215 0.11701 0.00000 0.06147HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00063 0.03043 0.01022 0.06454VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00000 0.00027 0.03793 0.00002GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.03748 0.00000 0.00603UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.12987 0.05250 0.01779 0.14472STREICHER_LSM1_TARGETS_UP
0.00067 0.00403 0.13073 0.02476BIOCARTA_TNFR2_PATHWAY
0.00032 0.00006 0.10060 0.01817ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00023 0.12346 0.00000 0.06336ELVIDGE_HYPOXIA_BY_DMOG_UP
0.00000 0.00000 0.00001 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.00000 0.00000 0.00000 0.00039GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00010 0.00475 0.00000 0.10013OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00723 0.04132 0.00000 0.02425ZUCCHI_METASTASIS_DN
0.07700 0.04137 0.01752 0.18870LEE_LIVER_CANCER_HEPATOBLAST
0.00000 0.05878 0.00000 0.01564NAGASHIMA_EGF_SIGNALING_UP
0.00000 0.00031 0.00000 0.00004PRAMOONJAGO_SOX4_TARGETS_UP
0.00002 0.00034 0.00000 0.15432PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00002 0.00978 0.00000 0.04711AMIT_EGF_RESPONSE_60_MCF10A
0.00000 0.01167 0.00038 0.05134HINATA_NFKB_TARGETS_FIBROBLAST_UP