BICLUSTER_ID : UPREG-326
PATHOGENS /5/ : pseudomonas aeruginosa,bacillus anthracis,mycobacterium tuberculosis,streptococcus pyogenes,brucella melitensis
TARGETS /6/ : NFKB1, IL6, IL1B, ICAM1, CCL2, PLAUR
Gene SetLeading Edge Genes
NETPATH IL 2 PATHWAY UPNFKB1, TRIM21, RGS16, IL6, IL1B, ICAM1, IER3, PLAUR
NETPATH IL 5 PATHWAY UPNFKB1, PLSCR1, BIRC3, NFKB2, CCL2, ICAM1, IER3
NCI IL23PATHWAYNFKB1, NFKBIA, IL1B
NETPATH IL 4 PATHWAY DOWNNFKBIA, GADD45B, ICAM1, CCL2, CXCL2
NETPATH IL 1 PATHWAY UPIL6, BIRC3, ICAM1, CXCL2
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
BIOCARTA TID PATHWAY
MISSIAGLIA REGULATED BY METHYLATION UP
BIOCARTA FREE PATHWAY
BIOCARTA IL10 PATHWAY
DAUER STAT3 TARGETS UP
NETPATH IL 3 PATHWAY UP
BIOCARTA NFKB PATHWAY
KEGG LEISHMANIA INFECTION
MCLACHLAN DENTAL CARIES UP
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
LINDSTEDT DENDRITIC CELL MATURATION B
FOSTER INFLAMMATORY RESPONSE LPS DN
MCLACHLAN DENTAL CARIES DN
KEGG ALLOGRAFT REJECTION
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
SIMBULAN UV RESPONSE NORMAL UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHOU INFLAMMATORY RESPONSE LPS UP
BIOCARTA INFLAM PATHWAY
SANA TNF SIGNALING UP
NETPATH IL 7 PATHWAY UPCXCL2
FOSTER INFLAMMATORY RESPONSE LPS UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
HARRIS HYPOXIA
NETPATH KIT RECEPTOR PATHWAY UP
VERHAAK AML WITH NPM1 MUTATED UP
GEISS RESPONSE TO DSRNA UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
HINATA NFKB TARGETS KERATINOCYTE UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
MARZEC IL2 SIGNALING UP
AMIT EGF RESPONSE 120 MCF10A
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
BIOCARTA LYM PATHWAY
GILMORE CORE NFKB PATHWAY
ZHU CMV ALL UP
DUTTA APOPTOSIS VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
HINATA NFKB TARGETS FIBROBLAST UP
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
bacillus anthracispseudomonas aeruginosa fdr440brucella melitensisstreptococcus pyogenesmycobacterium tuberculosisGeneSet Name
0.18345 0.00843 0.03203 0.01602 0.00008NETPATH_IL_2_PATHWAY_UP
0.00652 0.00726 0.01177 0.03974 0.00000NETPATH_IL_5_PATHWAY_UP
0.00010 0.01471 0.03782 0.00014 0.00126NCI_IL23PATHWAY
0.12825 0.00000 0.00471 0.00471 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.00738 0.00000 0.00061 0.03192 0.00602NETPATH_IL_1_PATHWAY_UP
0.00020 0.00195 0.10177 0.00010 0.00225KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.01740 0.00010 0.09531 0.02287 0.01104BIOCARTA_TID_PATHWAY
0.06111 0.00000 0.05845 0.01557 0.00000MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.04461 0.04271 0.14164 0.10876 0.06290BIOCARTA_FREE_PATHWAY
0.08594 0.01645 0.15511 0.03771 0.00336BIOCARTA_IL10_PATHWAY
0.00062 0.00085 0.00563 0.00038 0.00000DAUER_STAT3_TARGETS_UP
0.19023 0.15088 0.00052 0.00095 0.00171NETPATH_IL_3_PATHWAY_UP
0.09838 0.00100 0.00822 0.16684 0.00073BIOCARTA_NFKB_PATHWAY
0.01847 0.00027 0.01414 0.00061 0.00007KEGG_LEISHMANIA_INFECTION
0.11704 0.00001 0.01108 0.00000 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.00986 0.00068 0.03772 0.00000 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.00000 0.00000 0.01411 0.02304 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.09653 0.00037 0.00031 0.00568 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.12968 0.00017 0.01946 0.00000 0.00001MCLACHLAN_DENTAL_CARIES_DN
0.03072 0.05771 0.09553 0.03176 0.00549KEGG_ALLOGRAFT_REJECTION
0.00554 0.00000 0.03255 0.00000 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00000 0.00003 0.00644 0.00032 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00000 0.00000 0.00010 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00002 0.00642 0.00000 0.00000GAURNIER_PSMD4_TARGETS
0.13030 0.01311 0.02965 0.01756 0.04602SIMBULAN_UV_RESPONSE_NORMAL_UP
0.00009 0.00002 0.02218 0.05533 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00017 0.00019 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00000 0.00027 0.02743 0.06782 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00049 0.00030 0.03484 0.19333 0.05068BIOCARTA_INFLAM_PATHWAY
0.00096 0.00000 0.00362 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.04896 0.00003 0.02550 0.04416 0.00856NETPATH_IL_7_PATHWAY_UP
0.19461 0.09494 0.09817 0.00000 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.00240 0.00052 0.00944 0.11415 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00029 0.00011 0.00468 0.09492 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.07884 0.00003 0.04905 0.15102 0.00067HARRIS_HYPOXIA
0.01116 0.18259 0.02966 0.02708 0.00019NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00551 0.00218 0.01897 0.01128 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.03512 0.00007 0.09792 0.01876 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.02609 0.01678 0.05929 0.04007 0.00059KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00000 0.00000 0.05127 0.05930 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00215 0.00034 0.03717 0.02604 0.00060KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00000 0.04270 0.00023 0.00000BASSO_CD40_SIGNALING_UP
0.05995 0.01502 0.01700 0.13526 0.00127MARZEC_IL2_SIGNALING_UP
0.14343 0.00020 0.03700 0.12740 0.03451AMIT_EGF_RESPONSE_120_MCF10A
0.00345 0.02994 0.00824 0.00021 0.02521SOUCEK_MYC_TARGETS
0.00000 0.00000 0.00659 0.00455 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.02586 0.01705 0.10226 0.05182 0.18330BIOCARTA_LYM_PATHWAY
0.00319 0.00085 0.01568 0.06138 0.00092GILMORE_CORE_NFKB_PATHWAY
0.14821 0.02420 0.10116 0.06342 0.00000ZHU_CMV_ALL_UP
0.01600 0.00513 0.00246 0.02575 0.00002DUTTA_APOPTOSIS_VIA_NFKB
0.00000 0.00000 0.00050 0.05507 0.00002GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.00002 0.00015 0.00616 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00593 0.00002 0.15514 0.01593 0.00004MAHADEVAN_RESPONSE_TO_MP470_UP
0.00000 0.00000 0.15037 0.14412 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00253 0.00009 0.02236 0.00007 0.00176REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES