BICLUSTER_ID : UPREG-344
PATHOGENS /4/ : bacillus anthracis,yersinia enterocolitica,aeromonas caviae,ehrlichia chaffeensis
TARGETS /8/ : JUN, JAK2, WARS, CCL8, IL1B, IFNG, PIM1, TNF
Gene SetLeading Edge Genes
NCI IL23PATHWAYIL1B, CXCL1, IFNG, CXCL9, TNF
NCI IL27PATHWAYIL1B, IFNG, TNF
NCI IL12 2PATHWAYIL1B, JAK2, SOCS1, IFNG, CCL4
NETPATH IL 2 PATHWAY UPKLF6, GBP1, WARS, TRIM21, LCP2, IL1B, SOCS1, PBEF1, IFNG, IRF1, CCL4
SA MMP CYTOKINE CONNECTIONIL1B, TNF
NCI IL12 STAT4PATHWAYJUN, IRF1, IFNG
NETPATH IL 3 PATHWAY UPIL1B, SOCS1, CCL4
NETPATH IL 5 PATHWAY UPRHOH, LCP2, PIM1, CASP4
NETPATH IL 4 PATHWAY DOWNIRF1, TNF, GBP2
NETPATH IL 7 PATHWAY UPFAS, KLRK1, CXCL1, CCL8, CCL19, CCL4
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
SANA RESPONSE TO IFNG UP
BIOCARTA PML PATHWAY
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
DAUER STAT3 TARGETS UP
MAHAJAN RESPONSE TO IL1A UP
KEGG LEISHMANIA INFECTION
MCLACHLAN DENTAL CARIES UP
VARELA ZMPSTE24 TARGETS UP
AUJLA IL22 AND IL17A SIGNALING
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
BOYLAN MULTIPLE MYELOMA PCA1 UP
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
LINDSTEDT DENDRITIC CELL MATURATION B
FOSTER INFLAMMATORY RESPONSE LPS DN
MCLACHLAN DENTAL CARIES DN
KEGG ALLOGRAFT REJECTION
LINDSTEDT DENDRITIC CELL MATURATION A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
KIM LRRC3B TARGETS
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHU CMV 8 HR UP
ICHIBA GRAFT VERSUS HOST DISEASE 35D UP
SMID BREAST CANCER LUMINAL B DN
ZHOU INFLAMMATORY RESPONSE LPS UP
SANA TNF SIGNALING UP
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D UP
FOSTER INFLAMMATORY RESPONSE LPS UP
BROWNE HCMV INFECTION 2HR UP
BIOCARTA ASBCELL PATHWAY
CORUM REL-MAP3K8-RELA-TNIP2-PAPOLA COMPLEX
BROWNE INTERFERON RESPONSIVE GENES
KEGG JAK STAT SIGNALING PATHWAY
VERHAAK AML WITH NPM1 MUTATED UP
GEISS RESPONSE TO DSRNA UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
HINATA NFKB TARGETS KERATINOCYTE UP
BIOCARTA GRANULOCYTES PATHWAY
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX RPL6 RPL30 RPS13 CHUK DDX3X NFKB2 NFKBIB REL IKBKG NFKB1 MAP3K8 RELB GLG1 NFKBIA RELA TNIP2 GTF2I
BASSO CD40 SIGNALING UP
HESS TARGETS OF HOXA9 AND MEIS1 DN
SOUCEK MYC TARGETS
ZHU CMV ALL UP
DUTTA APOPTOSIS VIA NFKB
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
DIRMEIER LMP1 RESPONSE EARLY
SU THYMUS
MAHADEVAN RESPONSE TO MP470 UP
NCI XANTHINE FORMATION
KEGG AUTOIMMUNE THYROID DISEASE
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica p60 bcehrlichia chaffeensis wakullabacillus anthracisaeromonas caviaGeneSet Name
0.00000 0.00020 0.00010 0.00704NCI_IL23PATHWAY
0.00318 0.00004 0.00412 0.00317NCI_IL27PATHWAY
0.00140 0.00000 0.00781 0.00545NCI_IL12_2PATHWAY
0.00018 0.00006 0.18345 0.07215NETPATH_IL_2_PATHWAY_UP
0.00023 0.00000 0.15130 0.02492SA_MMP_CYTOKINE_CONNECTION
0.03431 0.00001 0.17208 0.14161NCI_IL12_STAT4PATHWAY
0.00000 0.00000 0.19023 0.00216NETPATH_IL_3_PATHWAY_UP
0.00159 0.00000 0.00652 0.07327NETPATH_IL_5_PATHWAY_UP
0.00040 0.00000 0.12825 0.01190NETPATH_IL_4_PATHWAY_DOWN
0.00028 0.00004 0.04896 0.16616NETPATH_IL_7_PATHWAY_UP
0.00000 0.00000 0.00020 0.01697KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00000 0.00000 0.09919 0.00000SANA_RESPONSE_TO_IFNG_UP
0.02683 0.00285 0.18545 0.12171BIOCARTA_PML_PATHWAY
0.00000 0.00547 0.15911 0.01924GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.02597 0.00307 0.00062 0.05120DAUER_STAT3_TARGETS_UP
0.00009 0.00447 0.01475 0.16652MAHAJAN_RESPONSE_TO_IL1A_UP
0.01693 0.00000 0.01847 0.05933KEGG_LEISHMANIA_INFECTION
0.00008 0.00000 0.11704 0.00003MCLACHLAN_DENTAL_CARIES_UP
0.15192 0.00013 0.13115 0.03175VARELA_ZMPSTE24_TARGETS_UP
0.00824 0.01045 0.19473 0.01459AUJLA_IL22_AND_IL17A_SIGNALING
0.00000 0.00000 0.00986 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.09493 0.00000 0.06128 0.00286BOYLAN_MULTIPLE_MYELOMA_PCA1_UP
0.00005 0.00014 0.14368 0.13954REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.00237 0.00000 0.00000 0.00053LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00000 0.00000 0.09653 0.00001FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00014 0.00000 0.12968 0.00003MCLACHLAN_DENTAL_CARIES_DN
0.01133 0.00014 0.03072 0.01652KEGG_ALLOGRAFT_REJECTION
0.00000 0.00000 0.00000 0.00124LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00000 0.00000 0.00000 0.00002SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.00000 0.00001GAURNIER_PSMD4_TARGETS
0.00041 0.00017 0.15773 0.00000KIM_LRRC3B_TARGETS
0.00000 0.00000 0.00000 0.00001ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00000 0.00000 0.07377 0.00058ZHU_CMV_8_HR_UP
0.00218 0.00000 0.11881 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP
0.00148 0.00000 0.02727 0.08643SMID_BREAST_CANCER_LUMINAL_B_DN
0.00000 0.00012 0.00000 0.01590ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.00096 0.00000SANA_TNF_SIGNALING_UP
0.00000 0.00084 0.16722 0.00109TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP
0.00000 0.00000 0.19461 0.01920FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.00673 0.11885 0.00022 0.05963BROWNE_HCMV_INFECTION_2HR_UP
0.13527 0.00252 0.09695 0.04179BIOCARTA_ASBCELL_PATHWAY
0.06284 0.16009 0.18566 0.01112CORUM_REL-MAP3K8-RELA-TNIP2-PAPOLA_COMPLEX
0.00000 0.00000 0.15574 0.00000BROWNE_INTERFERON_RESPONSIVE_GENES
0.00015 0.00097 0.18321 0.00316KEGG_JAK_STAT_SIGNALING_PATHWAY
0.00000 0.00000 0.00551 0.08932VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00000 0.00022 0.03512 0.00364GEISS_RESPONSE_TO_DSRNA_UP
0.00805 0.00252 0.02609 0.00700KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00000 0.00001 0.00000 0.06206HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00695 0.00012 0.03044 0.04491BIOCARTA_GRANULOCYTES_PATHWAY
0.01794 0.06742 0.00097 0.14885CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_RPL6_RPL30_RPS13_CHUK_DDX3X_NFKB2_NFKBIB_REL_IKBKG_NFKB1_MAP3K8_RELB_GLG1_NFKBIA_RELA_TNIP2__GTF2I
0.00003 0.00000 0.00000 0.00110BASSO_CD40_SIGNALING_UP
0.00004 0.00000 0.13442 0.01035HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00008 0.00027 0.00345 0.00169SOUCEK_MYC_TARGETS
0.00004 0.00083 0.14821 0.14609ZHU_CMV_ALL_UP
0.00013 0.00000 0.01600 0.05340DUTTA_APOPTOSIS_VIA_NFKB
0.00219 0.00000 0.15813 0.00443KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00009 0.00000 0.09323GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.00000 0.00000 0.00564DIRMEIER_LMP1_RESPONSE_EARLY
0.00701 0.00028 0.05053 0.09975SU_THYMUS
0.00000 0.00001 0.00593 0.00240MAHADEVAN_RESPONSE_TO_MP470_UP
0.12119 0.03882 0.17073 0.07666NCI_XANTHINE_FORMATION
0.11422 0.00607 0.12994 0.04468KEGG_AUTOIMMUNE_THYROID_DISEASE
0.00000 0.00000 0.00253 0.00008REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES