BICLUSTER_ID : UPREG-352
PATHOGENS /2/ : streptococcus pneumoniae,helicobacter pylori
TARGETS /3/ : IL6, PTGS2, JUN
Gene SetLeading Edge Genes
NETPATH TNF ALPHA PATHWAY DOWNJUN, CXCL1, JUNB, VEGF, NFKBIA, MAFF, IL6, GEM, PTGS2, TNFAIP3, CXCL2, BHLHB2, IER3
NETPATH IL 6 PATHWAY UPGADD45B, CXCL1, CEBPD, JUN, JUNB, MAFF, ZFP36, BHLHB2
NETPATH IL 7 PATHWAY UPCXCL1, JUN, CXCL2, MYC
NOJIMA SFRP2 TARGETS UP
CHEN HOXA5 TARGETS 6HR UP
BILD HRAS ONCOGENIC SIGNATURE
NCI NFAT TFPATHWAY
ONDER CDH1 TARGETS 3 DN
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
DEBOSSCHER NFKB TARGETS REPRESSED BY GLUCOCORTICOIDS
CHO NR4A1 TARGETS
DAZARD RESPONSE TO UV NHEK UP
SHEPARD CRUSH AND BURN MUTANT UP
AMIT EGF RESPONSE 60 HELA
CROONQUIST STROMAL STIMULATION UP
DAZARD UV RESPONSE CLUSTER G2
KANNAN TP53 TARGETS UP
LINDSTEDT DENDRITIC CELL MATURATION B
LEE SP4 THYMOCYTE
AMIT SERUM RESPONSE 40 MCF10A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
SAGIV CD24 TARGETS DN
SIMBULAN UV RESPONSE NORMAL UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
BIERIE INFLAMMATORY RESPONSE TGFB1
AMIT EGF RESPONSE 40 HELA
GESERICK TERT TARGETS DN
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
AMIT SERUM RESPONSE 120 MCF10A
WANG METHYLATED IN BREAST CANCER
BROWNE HCMV INFECTION 2HR UP
MAHADEVAN RESPONSE TO MP470 DN
JEON SMAD6 TARGETS UP
INGA TP53 TARGETS
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
AMIT EGF RESPONSE 40 MCF10A
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
GENTILE UV HIGH DOSE UP
KOBAYASHI EGFR SIGNALING 6HR DN
AMIT EGF RESPONSE 20 HELA
DAZARD UV RESPONSE CLUSTER G3
AMIT EGF RESPONSE 120 MCF10A
AMIT SERUM RESPONSE 60 MCF10A
CHASSOT SKIN WOUND
NAGASHIMA NRG1 SIGNALING UP
TIAN TNF SIGNALING VIA NFKB
ZERBINI RESPONSE TO SULINDAC UP
GENTILE UV LOW DOSE UP
LEE LIVER CANCER HEPATOBLAST
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
DIRMEIER LMP1 RESPONSE EARLY
GENTILE UV LOW DOSE DN
AMIT DELAYED EARLY GENES
KRIGE AMINO ACID DEPRIVATION
PRAMOONJAGO SOX4 TARGETS UP
FERRARI RESPONSE TO FENRETINIDE UP
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx1 mgephelicobacter pylori kx2 mgepstreptococcus pneumoniae tigr4streptococcus pneumoniae d39GeneSet Name
0.00203 0.00340 0.00000 0.10568NETPATH_TNF_ALPHA_PATHWAY_DOWN
0.00236 0.01969 0.00000 0.09713NETPATH_IL_6_PATHWAY_UP
0.00294 0.00019 0.00009 0.04346NETPATH_IL_7_PATHWAY_UP
0.00032 0.00000 0.00000 0.00013NOJIMA_SFRP2_TARGETS_UP
0.00126 0.00788 0.00007 0.01993CHEN_HOXA5_TARGETS_6HR_UP
0.00029 0.00132 0.00000 0.16121BILD_HRAS_ONCOGENIC_SIGNATURE
0.11283 0.09081 0.00004 0.02419NCI_NFAT_TFPATHWAY
0.00085 0.00020 0.00000 0.02816ONDER_CDH1_TARGETS_3_DN
0.00003 0.00007 0.00000 0.00000AMIT_EGF_RESPONSE_120_HELA
0.00067 0.00008 0.00000 0.16214DAUER_STAT3_TARGETS_UP
0.09299 0.12727 0.18502 0.07882DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS
0.00941 0.06859 0.11862 0.16140CHO_NR4A1_TARGETS
0.00624 0.01957 0.00000 0.03803DAZARD_RESPONSE_TO_UV_NHEK_UP
0.00460 0.07454 0.00000 0.10516SHEPARD_CRUSH_AND_BURN_MUTANT_UP
0.00002 0.00000 0.00000 0.00040AMIT_EGF_RESPONSE_60_HELA
0.03674 0.05041 0.00000 0.04326CROONQUIST_STROMAL_STIMULATION_UP
0.00079 0.00000 0.00000 0.00031DAZARD_UV_RESPONSE_CLUSTER_G2
0.00289 0.01451 0.00146 0.00590KANNAN_TP53_TARGETS_UP
0.00000 0.00000 0.00796 0.12766LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.09234 0.13635 0.00046 0.08967LEE_SP4_THYMOCYTE
0.00874 0.00219 0.00000 0.00000AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.00000 0.00000 0.00548SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00002 0.00000 0.09452 0.11854GAURNIER_PSMD4_TARGETS
0.03235 0.00458 0.00002 0.04465SAGIV_CD24_TARGETS_DN
0.02203 0.04290 0.00048 0.11717SIMBULAN_UV_RESPONSE_NORMAL_UP
0.00000 0.00000 0.00001 0.01862ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00293 0.01339 0.08439 0.17044IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00586 0.00543 0.00416 0.16336BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.00125 0.00053 0.00000 0.00001AMIT_EGF_RESPONSE_40_HELA
0.00257 0.00002 0.00000 0.00000GESERICK_TERT_TARGETS_DN
0.08369 0.01011 0.00068 0.10589GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.00289 0.00109 0.00000 0.00824AMIT_SERUM_RESPONSE_120_MCF10A
0.01982 0.01533 0.00000 0.09053WANG_METHYLATED_IN_BREAST_CANCER
0.00034 0.00890 0.00000 0.16198BROWNE_HCMV_INFECTION_2HR_UP
0.00340 0.00005 0.00000 0.00298MAHADEVAN_RESPONSE_TO_MP470_DN
0.00006 0.00000 0.11902 0.05332JEON_SMAD6_TARGETS_UP
0.12773 0.02719 0.00001 0.00256INGA_TP53_TARGETS
0.00215 0.00008 0.00000 0.02392HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00438 0.00018 0.00000 0.00028SESTO_RESPONSE_TO_UV_C3
0.05254 0.01511 0.00000 0.01077AMIT_EGF_RESPONSE_40_MCF10A
0.00000 0.00000 0.00000 0.00005UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00330 0.02855 0.00764 0.09576GENTILE_UV_HIGH_DOSE_UP
0.00064 0.00002 0.00001 0.01383KOBAYASHI_EGFR_SIGNALING_6HR_DN
0.02197 0.00435 0.00019 0.00481AMIT_EGF_RESPONSE_20_HELA
0.06558 0.01539 0.03617 0.18581DAZARD_UV_RESPONSE_CLUSTER_G3
0.02386 0.00229 0.00000 0.00088AMIT_EGF_RESPONSE_120_MCF10A
0.00013 0.00000 0.00000 0.00074AMIT_SERUM_RESPONSE_60_MCF10A
0.01494 0.00239 0.00000 0.00000CHASSOT_SKIN_WOUND
0.00000 0.00000 0.00000 0.00006NAGASHIMA_NRG1_SIGNALING_UP
0.00000 0.00000 0.00001 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.00318 0.00100 0.00038 0.10474ZERBINI_RESPONSE_TO_SULINDAC_UP
0.07690 0.13892 0.00028 0.16174GENTILE_UV_LOW_DOSE_UP
0.07700 0.10358 0.01752 0.08457LEE_LIVER_CANCER_HEPATOBLAST
0.00723 0.00076 0.00000 0.10715ZUCCHI_METASTASIS_DN
0.00000 0.00000 0.00000 0.00000NAGASHIMA_EGF_SIGNALING_UP
0.00157 0.00124 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.07884 0.15126 0.00037 0.16267GENTILE_UV_LOW_DOSE_DN
0.00013 0.00009 0.00000 0.02442AMIT_DELAYED_EARLY_GENES
0.00000 0.00000 0.00068 0.04793KRIGE_AMINO_ACID_DEPRIVATION
0.00000 0.00000 0.00000 0.00813PRAMOONJAGO_SOX4_TARGETS_UP
0.00008 0.00002 0.00024 0.11268FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00002 0.00000 0.00000 0.00000AMIT_EGF_RESPONSE_60_MCF10A