BICLUSTER_ID : UPREG-358
PATHOGENS /2/ : helicobacter pylori,ehrlichia chaffeensis
TARGETS /8/ : LCN2, XDH, JUN, HMOX1, CCL2, GLA, IL6, ICAM1
Gene SetLeading Edge Genes
NETPATH IL 1 PATHWAY UPBIRC3, LCN2, CXCL1, JUN, CCL2, NFKBIA, CCL7, IL6, ICAM1, CXCL2, MYC
GERY CEBP TARGETSGADD45B, LCN2, TRIB3, HMOX1, CXCL1, XDH, EREG, JUNB, DDIT3, GLA, SAA3P, IFRD1, MAFK
NETPATH IL 9 PATHWAY UPCCL7, LCN2, CCL2, JUNB, MYC
NETPATH IL 6 PATHWAY UPMAFF, GADD45B, CXCL1, JUN, CEBPB, JUNB
ST TUMOR NECROSIS FACTOR PATHWAYNFKBIA, BIRC3, JUN, NFKB2, TNFAIP3
NOJIMA SFRP2 TARGETS UP
CHEN HOXA5 TARGETS 6HR UP
NCI VWF INTERACTION WITH COLLAGEN
ONDER CDH1 TARGETS 3 DN
LEONARD HYPOXIA
DAUER STAT3 TARGETS UP
MAHAJAN RESPONSE TO IL1A UP
NCI CHEMOKINE RECEPTORS BIND CHEMOKINES
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
PARK TRETINOIN RESPONSE
AUJLA IL22 AND IL17A SIGNALING
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
CHEN HOXA5 TARGETS 9HR UP
LINDSTEDT DENDRITIC CELL MATURATION B
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
ELVIDGE HYPOXIA UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
BIERIE INFLAMMATORY RESPONSE TGFB1
GESERICK TERT TARGETS DN
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 5
BROWNE HCMV INFECTION 2HR UP
MAHADEVAN RESPONSE TO MP470 DN
HARRIS HYPOXIA
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
HINATA NFKB TARGETS KERATINOCYTE UP
BIOCARTA GRANULOCYTES PATHWAY
ELVIDGE HYPOXIA BY DMOG UP
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
DUTTA APOPTOSIS VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
CORUM NFKB1-NFKB2-REL-RELA-RELB COMPLEX
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
PRAMOONJAGO SOX4 TARGETS UP
CORUM ETS2-FOS-JUN COMPLEX
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
ELVIDGE HIF1A TARGETS DN
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx2 npgecehrlichia chaffeensis arkansaehrlichia chaffeensis wakullahelicobacter pylori kx2 mgephelicobacter pylori kx1 npgecGeneSet Name
0.08273 0.00744 0.00022 0.00000 0.00201NETPATH_IL_1_PATHWAY_UP
0.14043 0.01308 0.00116 0.00038 0.04422GERY_CEBP_TARGETS
0.03276 0.00097 0.00000 0.00202 0.00667NETPATH_IL_9_PATHWAY_UP
0.13630 0.00003 0.00000 0.01969 0.02074NETPATH_IL_6_PATHWAY_UP
0.02351 0.00584 0.00254 0.00008 0.01817ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.03559 0.01772 0.00340 0.00000 0.01127NOJIMA_SFRP2_TARGETS_UP
0.18281 0.01170 0.01388 0.00788 0.08749CHEN_HOXA5_TARGETS_6HR_UP
0.03014 0.00587 0.01285 0.19572 0.00540NCI_VWF_INTERACTION_WITH_COLLAGEN
0.07857 0.02809 0.00507 0.00020 0.06938ONDER_CDH1_TARGETS_3_DN
0.00289 0.01232 0.00008 0.00000 0.00008LEONARD_HYPOXIA
0.04938 0.01097 0.00307 0.00008 0.01934DAUER_STAT3_TARGETS_UP
0.05579 0.01198 0.00447 0.00001 0.00083MAHAJAN_RESPONSE_TO_IL1A_UP
0.10173 0.06101 0.05726 0.17390 0.00902NCI_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.11321 0.01021 0.00276 0.00622 0.14559NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.03059 0.00097 0.00095 0.09790 0.04031PARK_TRETINOIN_RESPONSE
0.08713 0.00697 0.01045 0.01624 0.04599AUJLA_IL22_AND_IL17A_SIGNALING
0.01462 0.00094 0.00014 0.06781 0.00213REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.09671 0.01709 0.00291 0.00000 0.00899CHEN_HOXA5_TARGETS_9HR_UP
0.00320 0.00007 0.00000 0.00000 0.00011LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00000 0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00011 0.00000 0.00000 0.00000 0.00000GAURNIER_PSMD4_TARGETS
0.09761 0.01170 0.00027 0.00095 0.11617ELVIDGE_HYPOXIA_UP
0.08415 0.00007 0.00003 0.00677 0.00796GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.01844 0.00000 0.00000 0.00000 0.00002ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.03130 0.03251 0.02732 0.00543 0.00805BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.01236 0.00047 0.00032 0.00002 0.01048GESERICK_TERT_TARGETS_DN
0.14330 0.00697 0.02739 0.00313 0.02657YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5
0.03942 0.15614 0.11885 0.00890 0.02678BROWNE_HCMV_INFECTION_2HR_UP
0.09615 0.18500 0.08720 0.00005 0.09518MAHADEVAN_RESPONSE_TO_MP470_DN
0.01945 0.00160 0.00025 0.00009 0.08612HARRIS_HYPOXIA
0.03267 0.02814 0.00336 0.00000 0.00603UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.16190 0.00055 0.00001 0.00000 0.00256HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.01885 0.00024 0.00012 0.12825 0.00519BIOCARTA_GRANULOCYTES_PATHWAY
0.05588 0.04510 0.00131 0.00024 0.06336ELVIDGE_HYPOXIA_BY_DMOG_UP
0.01521 0.00003 0.00027 0.00002 0.00009SOUCEK_MYC_TARGETS
0.00000 0.00003 0.00000 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.03297 0.00000 0.00000 0.00000 0.05736DUTTA_APOPTOSIS_VIA_NFKB
0.01942 0.00001 0.00009 0.00000 0.00039GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.06149 0.16701 0.02218 0.00445 0.03228CORUM_NFKB1-NFKB2-REL-RELA-RELB_COMPLEX
0.03486 0.10538 0.00899 0.00076 0.02425ZUCCHI_METASTASIS_DN
0.01745 0.00040 0.00000 0.00000 0.01564NAGASHIMA_EGF_SIGNALING_UP
0.14826 0.00000 0.00000 0.00124 0.06932DIRMEIER_LMP1_RESPONSE_EARLY
0.00810 0.00029 0.00001 0.00001 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.00069 0.07569 0.00099 0.00000 0.00004PRAMOONJAGO_SOX4_TARGETS_UP
0.12452 0.05509 0.07788 0.14593 0.10242CORUM_ETS2-FOS-JUN_COMPLEX
0.10685 0.00358 0.00151 0.00009 0.05134HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.03534 0.02646 0.00070 0.00000 0.04711AMIT_EGF_RESPONSE_60_MCF10A
0.03088 0.08874 0.02625 0.00973 0.07454ELVIDGE_HIF1A_TARGETS_DN
0.00042 0.00000 0.00000 0.00000 0.00000REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES