BICLUSTER_ID : UPREG-360
PATHOGENS /3/ : escherichia coli,porphyromonas gingivalis,shigella dysenteriae
TARGETS /8/ : CCL8, CCL2, PLAU, F3, IL1B, PTGS2, IL8, PLAUR
Gene SetLeading Edge Genes
NETPATH IL 3 PATHWAY UPTGFA, FCER2, SOCS3, IL1B, CCL2, IL8, MYC
NETPATH EGFR1 PATHWAY UPPLAU, TGFA, SOX9, TNFAIP3, PTGS2, CTGF, MYC, DUSP1, PLAUR
NETPATH IL 7 PATHWAY UPCXCL1, CCL8, IL8, MYC
NETPATH IL 4 PATHWAY UPSTK17B, REL, CCL2, CH25H, IL10, SOCS3, IL10RA, F3, INHBA, RIPK2, HIST2H2BE, SERPINB4, MYC
NCI ATF2 PATHWAYSOCS3, PLAU, ATF3, DUSP5, DUSP1
NETPATH IL 9 PATHWAY UPSOCS3, IL13, CCL2, MYC, IL5RA
NOJIMA SFRP2 TARGETS UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
LINDGREN BLADDER CANCER CLUSTER 2B
VANHARANTA UTERINE FIBROID DN
KEGG ASTHMA
REACTOME HORMONE BIOSYNTHESIS
LINDSTEDT DENDRITIC CELL MATURATION B
HALMOS CEBPA TARGETS UP
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
CHANDRAN METASTASIS DN
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
NETPATH IL 4 PATHWAY DOWN
MAHADEVAN RESPONSE TO MP470 DN
RIGGI EWING SARCOMA PROGENITOR UP
BUDHU LIVER CANCER METASTASIS DN
HARRIS HYPOXIA
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION SUSTAINDED IN ERYTHROCYTE UP
HINATA NFKB TARGETS KERATINOCYTE UP
GENTILE UV HIGH DOSE UP
DAZARD UV RESPONSE CLUSTER G3
OSADA ASCL1 TARGETS DN
AMIT SERUM RESPONSE 60 MCF10A
SOUCEK MYC TARGETS
NAGASHIMA NRG1 SIGNALING UP
ZERBINI RESPONSE TO SULINDAC UP
FRASOR RESPONSE TO ESTRADIOL DN
BILBAN B CLL LPL DN
NCI PROSTANOID LIGAND RECEPTORS
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
ZHOU INFLAMMATORY RESPONSE LIVE UP
DAUER STAT3 TARGETS UP
NETPATH IL 6 PATHWAY UPSOCS3, GADD45B, CXCL1, PRDM1
WINTER HYPOXIA METAGENE
DAZARD RESPONSE TO UV NHEK UP
MCLACHLAN DENTAL CARIES UP
GAJATE RESPONSE TO TRABECTEDIN UP
BERENJENO TRANSFORMED BY RHOA FOREVER DN
AMIT EGF RESPONSE 60 HELA
DAZARD UV RESPONSE CLUSTER G2
TAVOR CEBPA TARGETS UP
MCLACHLAN DENTAL CARIES DN
DORN ADENOVIRUS INFECTION 24HR UP
SEKI INFLAMMATORY RESPONSE LPS UP
DAZARD UV RESPONSE CLUSTER G24
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
BIERIE INFLAMMATORY RESPONSE TGFB1
NCI IL23PATHWAY
GESERICK TERT TARGETS DN
CLASPER LYMPHATIC VESSELS DURING METASTASIS UP
AMIT SERUM RESPONSE 120 MCF10A
RICKMAN HEAD AND NECK CANCER C
SESTO RESPONSE TO UV C3
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
BROCKE APOPTOSIS REVERSED BY IL6
GEISS RESPONSE TO DSRNA UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
TIAN TNF SIGNALING VIA NFKB
IIZUKA RECURRENT LIVER CANCER
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
GOUYER TATI TARGETS UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
TURASHVILI BREAST DUCTAL CARCINOMA VS LOBULAR NORMAL DN
AMIT DELAYED EARLY GENES
WATTEL AUTONOMOUS THYROID ADENOMA DN
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 1
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
porphyromonas gingivalisshigella dysenteriaeescherichia coliGeneSet Name
0.12641 0.00147 0.00000NETPATH_IL_3_PATHWAY_UP
0.08355 0.00148 0.00008NETPATH_EGFR1_PATHWAY_UP
0.01741 0.04120 0.00000NETPATH_IL_7_PATHWAY_UP
0.03326 0.01729 0.00129NETPATH_IL_4_PATHWAY_UP
0.00897 0.00000 0.01874NCI_ATF2_PATHWAY
0.01126 0.05058 0.00028NETPATH_IL_9_PATHWAY_UP
0.11857 0.00035 0.00018NOJIMA_SFRP2_TARGETS_UP
0.03623 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.02363 0.00252 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.12757 0.18538 0.01415LINDGREN_BLADDER_CANCER_CLUSTER_2B
0.15414 0.08927 0.00612VANHARANTA_UTERINE_FIBROID_DN
0.03097 0.19147 0.01109KEGG_ASTHMA
0.04557 0.01249 0.00661REACTOME_HORMONE_BIOSYNTHESIS
0.02335 0.00053 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.03979 0.00005 0.00001HALMOS_CEBPA_TARGETS_UP
0.02386 0.00004 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00457 0.00034 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.10959 0.00098 0.00634CHANDRAN_METASTASIS_DN
0.04059 0.00648 0.00026IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00131 0.00000 0.00000AMIT_EGF_RESPONSE_40_HELA
0.04210 0.15816 0.01179GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.00395 0.16501 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.01107 0.00000 0.00317MAHADEVAN_RESPONSE_TO_MP470_DN
0.12440 0.14472 0.00632RIGGI_EWING_SARCOMA_PROGENITOR_UP
0.10290 0.10833 0.00126BUDHU_LIVER_CANCER_METASTASIS_DN
0.08079 0.00501 0.00034HARRIS_HYPOXIA
0.07753 0.11110 0.00807TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP
0.00133 0.00078 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.06659 0.04599 0.00081GENTILE_UV_HIGH_DOSE_UP
0.12179 0.00253 0.00510DAZARD_UV_RESPONSE_CLUSTER_G3
0.00441 0.01483 0.00002OSADA_ASCL1_TARGETS_DN
0.00000 0.00000 0.00109AMIT_SERUM_RESPONSE_60_MCF10A
0.03916 0.02047 0.00037SOUCEK_MYC_TARGETS
0.00124 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.02341 0.07968 0.02814ZERBINI_RESPONSE_TO_SULINDAC_UP
0.01471 0.04603 0.02658FRASOR_RESPONSE_TO_ESTRADIOL_DN
0.09608 0.00008 0.14289BILBAN_B_CLL_LPL_DN
0.11546 0.11438 0.01743NCI_PROSTANOID_LIGAND_RECEPTORS
0.00483 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.18333 0.06328 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.12784 0.00006 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.00811 0.00005 0.00003DAUER_STAT3_TARGETS_UP
0.09273 0.00000 0.00000NETPATH_IL_6_PATHWAY_UP
0.16096 0.04655 0.02164WINTER_HYPOXIA_METAGENE
0.10008 0.00111 0.00002DAZARD_RESPONSE_TO_UV_NHEK_UP
0.08054 0.01598 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.03047 0.10594 0.00098GAJATE_RESPONSE_TO_TRABECTEDIN_UP
0.06745 0.00170 0.00016BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.11163 0.00007 0.00523AMIT_EGF_RESPONSE_60_HELA
0.01540 0.00032 0.00004DAZARD_UV_RESPONSE_CLUSTER_G2
0.02033 0.00349 0.00020TAVOR_CEBPA_TARGETS_UP
0.08235 0.02949 0.00002MCLACHLAN_DENTAL_CARIES_DN
0.08165 0.03433 0.14299DORN_ADENOVIRUS_INFECTION_24HR_UP
0.00125 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.09662 0.11525 0.17607DAZARD_UV_RESPONSE_CLUSTER_G24
0.00127 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.06702 0.05553 0.01522BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.00584 0.09953 0.00000NCI_IL23PATHWAY
0.03305 0.00000 0.00083GESERICK_TERT_TARGETS_DN
0.00124 0.14239 0.03242CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP
0.00000 0.00021 0.00011AMIT_SERUM_RESPONSE_120_MCF10A
0.16035 0.05565 0.00000RICKMAN_HEAD_AND_NECK_CANCER_C
0.00266 0.00000 0.00001SESTO_RESPONSE_TO_UV_C3
0.05737 0.00000 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.14398 0.00055 0.00002BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.12681 0.01687 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.00000 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00000 0.00005 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.03888 0.12265 0.02641IIZUKA_RECURRENT_LIVER_CANCER
0.09753 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.08157 0.05947 0.03224GOUYER_TATI_TARGETS_UP
0.03617 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.11913 0.00154 0.00010LEE_LIVER_CANCER_HEPATOBLAST
0.00025 0.00000 0.00003NAGASHIMA_EGF_SIGNALING_UP
0.16366 0.11124 0.03241TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN
0.05191 0.00000 0.00082AMIT_DELAYED_EARLY_GENES
0.00215 0.00132 0.02507WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN
0.10670 0.00000 0.02690PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.15853 0.03633 0.08745YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1
0.03916 0.00153 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00000 0.00000 0.00000AMIT_EGF_RESPONSE_60_MCF10A