BICLUSTER_ID : UPREG-376
PATHOGENS /3/ : escherichia coli,aeromonas caviae,helicobacter pylori
TARGETS /4/ : ICAM1, PIM1, TNFRSF1B, TLR2
Gene SetLeading Edge Genes
NETPATH IL 4 PATHWAY DOWNNFKBIA, ICAM1, IRF1, TLR2
NETPATH IL 6 PATHWAY UPCXCL1, IRF1, BCL3, PIM1
ST TUMOR NECROSIS FACTOR PATHWAYNFKBIA, BIRC3, NFKBIE, TNFRSF1B, CFLAR
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
NETPATH IL 3 PATHWAY UP
NETPATH IL 9 PATHWAY UPBCL3, MYC
MAHAJAN RESPONSE TO IL1A UP
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
MCLACHLAN DENTAL CARIES UP
AUJLA IL22 AND IL17A SIGNALING
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
ISHIKAWA STING SIGNALING
LINDSTEDT DENDRITIC CELL MATURATION B
SA MMP CYTOKINE CONNECTION
NCI CD40 PATHWAYNFKBIA, BIRC3, TNFAIP3, MYC
MCLACHLAN DENTAL CARIES DN
LINDSTEDT DENDRITIC CELL MATURATION A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
RADAEVA RESPONSE TO IFNA1 UP
WALLACE PROSTATE CANCER RACE UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHU CMV 8 HR UP
ZHOU INFLAMMATORY RESPONSE LPS UP
NCI IL23PATHWAYNFKBIA, CXCL1
SANA TNF SIGNALING UP
FOSTER INFLAMMATORY RESPONSE LPS UP
BROWNE HCMV INFECTION 2HR UP
XU HGF TARGETS INDUCED BY AKT1 6HR
CORUM REL-MAP3K8-RELA-TNIP2-PAPOLA COMPLEXMAP3K8
KEGG COMPLEMENT AND COAGULATION CASCADES
VERHAAK AML WITH NPM1 MUTATED UP
ROETH TERT TARGETS UP
DER IFN BETA RESPONSE UP
GEISS RESPONSE TO DSRNA UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
HINATA NFKB TARGETS KERATINOCYTE UP
MARKEY RB1 ACUTE LOF UP
GALI TP53 TARGETS APOPTOTIC UP
BIOCARTA GRANULOCYTES PATHWAY
BASSO CD40 SIGNALING UP
SOUCEK MYC TARGETS
ZHU CMV ALL UP
DUTTA APOPTOSIS VIA NFKB
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP
DIRMEIER LMP1 RESPONSE EARLY
DER IFN GAMMA RESPONSE UP
MAHADEVAN RESPONSE TO MP470 UP
REACTOME INITIAL TRIGGERING OF COMPLEMENT
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx2 mgepaeromonas caviahelicobacter pylori kx1 npgecescherichia coliGeneSet Name
0.00009 0.01190 0.00644 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.01969 0.10211 0.02074 0.00000NETPATH_IL_6_PATHWAY_UP
0.00008 0.11624 0.01817 0.00026ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00022 0.01697 0.06985 0.00000KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00254 0.10841 0.14476 0.00000KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00541 0.01924 0.18497 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00008 0.05120 0.01934 0.00003DAUER_STAT3_TARGETS_UP
0.00002 0.00001 0.00000 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.13629 0.00216 0.05322 0.00000NETPATH_IL_3_PATHWAY_UP
0.00202 0.07320 0.00667 0.00028NETPATH_IL_9_PATHWAY_UP
0.00001 0.16652 0.00083 0.00000MAHAJAN_RESPONSE_TO_IL1A_UP
0.00467 0.00001 0.10968 0.04537NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.00006 0.00003 0.02102 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.01624 0.01459 0.04599 0.00129AUJLA_IL22_AND_IL17A_SIGNALING
0.07361 0.00000 0.00000 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.06781 0.13954 0.00213 0.00015REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.10233 0.00242 0.00285 0.00301ISHIKAWA_STING_SIGNALING
0.00000 0.00053 0.00011 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.11687 0.02492 0.13965 0.00133SA_MMP_CYTOKINE_CONNECTION
0.00002 0.06428 0.14335 0.00010NCI_CD40_PATHWAY
0.00040 0.00003 0.06509 0.00002MCLACHLAN_DENTAL_CARIES_DN
0.00000 0.00124 0.00003 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00000 0.00002 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00001 0.00000 0.00000GAURNIER_PSMD4_TARGETS
0.10408 0.00000 0.00052 0.00000RADAEVA_RESPONSE_TO_IFNA1_UP
0.14952 0.00000 0.03695 0.00004WALLACE_PROSTATE_CANCER_RACE_UP
0.00000 0.00001 0.00002 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.11599 0.00058 0.00000 0.00000ZHU_CMV_8_HR_UP
0.00059 0.01590 0.00001 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.01454 0.00704 0.14576 0.00000NCI_IL23PATHWAY
0.00000 0.00000 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.00313 0.01920 0.03879 0.00011FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.00890 0.05963 0.02678 0.00014BROWNE_HCMV_INFECTION_2HR_UP
0.06063 0.15750 0.01849 0.00014XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR
0.11696 0.01112 0.05756 0.01415CORUM_REL-MAP3K8-RELA-TNIP2-PAPOLA_COMPLEX
0.11605 0.00028 0.00989 0.00386KEGG_COMPLEMENT_AND_COAGULATION_CASCADES
0.00145 0.08932 0.06454 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.08283 0.00363 0.00396 0.00141ROETH_TERT_TARGETS_UP
0.12957 0.00003 0.00085 0.00000DER_IFN_BETA_RESPONSE_UP
0.00000 0.00364 0.00002 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.01719 0.00700 0.00515 0.00000KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00000 0.06206 0.00256 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.09595 0.00000 0.00008 0.00000MARKEY_RB1_ACUTE_LOF_UP
0.00280 0.05625 0.06541 0.04486GALI_TP53_TARGETS_APOPTOTIC_UP
0.12825 0.04491 0.00519 0.15379BIOCARTA_GRANULOCYTES_PATHWAY
0.01278 0.00110 0.12757 0.00000BASSO_CD40_SIGNALING_UP
0.00002 0.00169 0.00009 0.00037SOUCEK_MYC_TARGETS
0.01057 0.14609 0.00201 0.00000ZHU_CMV_ALL_UP
0.00000 0.05340 0.05736 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.01658 0.00443 0.14588 0.00000KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.09323 0.00039 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.10547 0.00108 0.09552 0.00008BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP
0.00124 0.00564 0.06932 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.03368 0.00005 0.00454 0.00000DER_IFN_GAMMA_RESPONSE_UP
0.00001 0.00240 0.00000 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.12910 0.00002 0.09706 0.14625REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT
0.00000 0.00008 0.00000 0.00000REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES