BICLUSTER_ID : UPREG-390
PATHOGENS /6/ : brucella neotomae,listeria monocytogenes,fusobacterium nucleatum,brucella ovis,mycobacterium tuberculosis,brucella melitensis
TARGETS /1/ : TNFRSF1B
Gene SetLeading Edge Genes
NETPATH TNF ALPHA PATHWAY UPNFKBIA, ZFP36, JUNB, TNFRSF1B, TMSB10, EMP3
NCI AUTODEGRADATION OF CDH1 BY CDH1 APC C
REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G
NCI CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6
DAZARD RESPONSE TO UV NHEK UP
ZUCCHI METASTASIS UP
PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN
NCI HOST INTERACTIONS OF HIV FACTORSPSMA1, PSMD14, PSMB7, PSMA2
AMIT SERUM RESPONSE 40 MCF10A
NCI APC C CDC20 MEDIATED DEGRADATION OF SECURIN
REACTOME P53 INDEPENDENT DNA DAMAGE RESPONSE
CORUM PA28-20S PROTEASOMEPSMA1, PSMB7
NCI UBIQUITIN DEPENDENT DEGRADATION OF CYCLIN D1PSMA1, PSMB7
CORUM 20S PROTEASOME
NCI SCF SKP2 MEDIATED DEGRADATION OF P27 P21PSMA1, PSMD14, PSMB7, PSMA2
REACTOME STABILIZATION OF P53
CORUM 26S PROTEASOME
NCI REGULATION OF ORNITHINE DECARBOXYLASE ODC
REACTOME REGULATION OF ORNITHINE DECARBOXYLASE
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21
CORUM PA700-20S-PA28 COMPLEXPSMA1, PSMD14, PSMB7, PSMA2
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1
KIM WT1 TARGETS UP
ONDER CDH1 TARGETS 1 DN
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
CORUM PA28GAMMA-20S PROTEASOME
NCI SCF BETA TRCP MEDIATED DEGRADATION OF EMI1PSMA1, PSMD14, PSMB7, PSMA2
KEGG PROTEASOME
NCI VIF MEDIATED DEGRADATION OF APOBEC3GPSMA1, PSMD14, PSMB7, PSMA2
NCI REGULATION OF ACTIVATED PAK 2P34 BY PROTEASOME MEDIATED DEGRADATION1PSMA1, PSMD14, PSMB7, PSMA2
NCI REGULATION OF ACTIVATED PAK 2P34 BY PROTEASOME MEDIATED DEGRADATIONPSMA1, PSMD14, PSMB7, PSMA2
NCI DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEXPSMA1, PSMD14, PSMB7, PSMA2
DIRMEIER LMP1 RESPONSE EARLY
NCI UBIQUITIN MEDIATED DEGRADATION OF PHOSPHORYLATED CDC25APSMA1, PSMD14, PSMB7, PSMA2
NCI APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1
NCI VPU MEDIATED DEGRADATION OF CD4PSMA1, PSMD14, PSMB7, PSMA2
Color legend
q-value10.20.050.010.0010.0001
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TABLE OF Q-VALUES
brucella melitensislisteria monocytogenesmycobacterium tuberculosisfusobacterium nucleatumbrucella ovisbrucella neotomaeGeneSet Name
0.09797 0.00123 0.00534 0.01710 0.15651 0.10261NETPATH_TNF_ALPHA_PATHWAY_UP
0.01494 0.00143 0.08317 0.04367 0.05755 0.00352NCI_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C
0.00544 0.00069 0.00468 0.03536 0.03399 0.00129REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G
0.00670 0.00070 0.03019 0.00676 0.05538 0.00247NCI_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6
0.10000 0.01225 0.00196 0.01697 0.12521 0.11484DAZARD_RESPONSE_TO_UV_NHEK_UP
0.06704 0.01901 0.03573 0.11866 0.12139 0.05743ZUCCHI_METASTASIS_UP
0.00728 0.00306 0.00008 0.07677 0.04589 0.00660PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN
0.00509 0.00045 0.00787 0.00122 0.03263 0.00221NCI_HOST_INTERACTIONS_OF_HIV_FACTORS
0.19786 0.00799 0.00000 0.00145 0.08142 0.03264AMIT_SERUM_RESPONSE_40_MCF10A
0.01361 0.00482 0.17875 0.00541 0.03969 0.00375NCI_APC_C_CDC20_MEDIATED_DEGRADATION_OF_SECURIN
0.00576 0.00031 0.01493 0.02476 0.03125 0.00150REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE
0.02407 0.00254 0.01169 0.01729 0.01964 0.00236CORUM_PA28-20S_PROTEASOME
0.00535 0.00081 0.00551 0.00923 0.02768 0.00204NCI_UBIQUITIN_DEPENDENT_DEGRADATION_OF_CYCLIN_D1
0.03742 0.00025 0.05869 0.03508 0.01291 0.00472CORUM_20S_PROTEASOME
0.00816 0.00110 0.01422 0.00283 0.08116 0.00381NCI_SCF_SKP2__MEDIATED_DEGRADATION_OF_P27_P21
0.01983 0.00163 0.00975 0.12783 0.07503 0.00387REACTOME_STABILIZATION_OF_P53
0.00466 0.00002 0.01696 0.01436 0.00480 0.00147CORUM_26S_PROTEASOME
0.00707 0.00061 0.02665 0.06082 0.03307 0.00259NCI_REGULATION_OF_ORNITHINE_DECARBOXYLASE__ODC_
0.02111 0.00069 0.02161 0.08069 0.13579 0.00938REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE
0.00499 0.00028 0.07509 0.18100 0.03357 0.00119REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21
0.00339 0.00011 0.01568 0.03471 0.01371 0.00108CORUM_PA700-20S-PA28_COMPLEX
0.00836 0.00013 0.03860 0.09371 0.03302 0.00216REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1
0.10192 0.01564 0.00007 0.00000 0.09311 0.10627KIM_WT1_TARGETS_UP
0.09382 0.00003 0.07350 0.00000 0.11964 0.17331ONDER_CDH1_TARGETS_1_DN
0.05866 0.00007 0.00000 0.04380 0.01384 0.00256UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.03921 0.00011 0.08660 0.11452 0.01273 0.00385CORUM_PA28GAMMA-20S_PROTEASOME
0.00899 0.00045 0.00570 0.00518 0.08031 0.00384NCI_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1
0.00674 0.00038 0.00367 0.03071 0.03342 0.00158KEGG_PROTEASOME
0.00472 0.00069 0.00789 0.00252 0.03866 0.00197NCI_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G
0.00824 0.00062 0.00809 0.00670 0.04956 0.00256NCI_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION1
0.00456 0.00056 0.00636 0.00225 0.03113 0.00221NCI_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION
0.03915 0.00037 0.00348 0.00680 0.18023 0.00597NCI_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX
0.00015 0.00199 0.00000 0.01976 0.01330 0.00214DIRMEIER_LMP1_RESPONSE_EARLY
0.00640 0.00046 0.01224 0.00176 0.04348 0.00234NCI_UBIQUITIN_MEDIATED_DEGRADATION_OF_PHOSPHORYLATED_CDC25A
0.01608 0.00178 0.08118 0.04730 0.05732 0.00390NCI_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1
0.00625 0.00119 0.00707 0.00491 0.08155 0.00369NCI_VPU_MEDIATED_DEGRADATION_OF_CD4