BICLUSTER_ID : UPREG-40
PATHOGENS /4/ : escherichia coli,yersinia enterocolitica,shigella dysenteriae,ehrlichia chaffeensis
TARGETS /13/ : NFKB1, CCL20, JAK2, CCL8, CCL2, TNFRSF1B, PLAU, CYP1B1, IL6, IL1B, IL1R1, TNF, PLAUR
Gene SetLeading Edge Genes
NETPATH IL 2 PATHWAY UPTNFRSF1B, SOCS3, CCL4, IER3, IFIT1, NFKB1, KLF6, VIM, TNFSF10, GADD45G, TRIM21, IL1B, PBEF1, IL1R1, TNF, PLAUR
NETPATH IL 1 PATHWAY UPNFKB1, CCL20, CXCL1, CCL2, HBEGF, PTGES, IL1B, PBEF1, MT2A, CXCL2, PTX3, CCL4
NETPATH IL 4 PATHWAY UPNFKB1, REL, CCL2, CH25H, IL10, CYP1B1, SOCS3, RIPK2, PTX3
NETPATH IL 3 PATHWAY UPSOCS3, IL1B, CSF1, CCL2, CCL4, TNF
NETPATH IL 5 PATHWAY UPNFKB1, PLSCR1, REL, NFKB2, CCL2, HBEGF, LCP2, IL1B, CASP4, IER3
NCI IL6 7PATHWAYSOCS3, IL6, JAK2, JUNB, IRF1
NETPATH KIT RECEPTOR PATHWAY UPJUNB, CCL2, TNF, IER3
NETPATH IL 9 PATHWAY UPSOCS3, CCL2, JUNB
NETPATH IL 7 PATHWAY UPCXCL1, CCL8, CXCL2, CCL4
GERY CEBP TARGETSGADD45B, CXCL1, EREG, JUNB, GADD45G, ATF3, PTX3, PLAUR
NCI ATF2 PATHWAYPLAU, SOCS3, ATF3, DUSP8
NETPATH IL 6 PATHWAY UPSOCS3, MAFF, GADD45B, CXCL1, JUNB, MAP3K8, TNF
BIOCARTA IL10 PATHWAY
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
BIOCARTA NFKB PATHWAY
MAHAJAN RESPONSE TO IL1A UP
LINDGREN BLADDER CANCER CLUSTER 2B
VARELA ZMPSTE24 TARGETS UP
MUELLER COMMON TARGETS OF AML FUSIONS DN
CHEN LVAD SUPPORT OF FAILING HEART UP
TENEDINI MEGAKARYOCYTE MARKERS
LINDSTEDT DENDRITIC CELL MATURATION B
BIOCARTA IL1R PATHWAY
BRUECKNER TARGETS OF MIRLET7A3 DN
SAKAI CHRONIC HEPATITIS VS LIVER CANCER DN
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
NETPATH IL 1 PATHWAY
ELVIDGE HYPOXIA UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
NETPATH TGFBETA RECEPTOR PATHWAY UP
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 5
BROWNE HCMV INFECTION 10HR UP
JEON SMAD6 TARGETS UP
MITSIADES RESPONSE TO APLIDIN UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
NUYTTEN NIPP1 TARGETS UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION SUSTAINDED IN ERYTHROCYTE UP
HINATA NFKB TARGETS KERATINOCYTE UP
MARKEY RB1 ACUTE LOF UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
DAZARD UV RESPONSE CLUSTER G3
XU HGF TARGETS INDUCED BY AKT1 48HR UP
KEGG TYPE II DIABETES MELLITUS
OSADA ASCL1 TARGETS DN
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS MAGENTA UP
HUANG FOXA2 TARGETS UP
DELYS THYROID CANCER UP
TSAI RESPONSE TO IONIZING RADIATION
DIRMEIER LMP1 RESPONSE EARLY
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN
WOTTON RUNX TARGETS UP
DAZARD UV RESPONSE CLUSTER G4
NCI REG GR PATHWAY
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
NCI NFAT TFPATHWAY
ZHOU INFLAMMATORY RESPONSE LIVE UP
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP
AMIT EGF RESPONSE 120 HELA
BIOCARTA RANKL PATHWAY
DANG REGULATED BY MYC DN
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
DAZARD RESPONSE TO UV NHEK UP
MCLACHLAN DENTAL CARIES UP
WINTER HYPOXIA METAGENE
BROWNE HCMV INFECTION 8HR UP
GAJATE RESPONSE TO TRABECTEDIN UP
NEWMAN ERCC6 TARGETS UP
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2
PODAR RESPONSE TO ADAPHOSTIN UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
FOSTER INFLAMMATORY RESPONSE LPS DN
TAVOR CEBPA TARGETS UP
GAURNIER PSMD4 TARGETS
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
NETPATH TNF ALPHA PATHWAY UP
NCI IL23PATHWAY
ZHOU INFLAMMATORY RESPONSE LPS UP
GESERICK TERT TARGETS DN
NOJIMA SFRP2 TARGETS DN
NETPATH TGFBETA RECEPTOR PATHWAY DOWN
CLASPER LYMPHATIC VESSELS DURING METASTASIS UP
AMIT SERUM RESPONSE 120 MCF10A
BROWNE HCMV INFECTION 2HR UP
DORN ADENOVIRUS INFECTION 24HR DN
NCI IL1PATHWAY
SESTO RESPONSE TO UV C3
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
GEISS RESPONSE TO DSRNA UP
NCI P53DOWNSTREAMPATHWAY
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX RPL6 RPL30 RPS13 CHUK DDX3X NFKB2 NFKBIB REL IKBKG NFKB1 MAP3K8 RELB GLG1 NFKBIA RELA TNIP2 GTF2I
GENTILE UV HIGH DOSE DN
SPIRA SMOKERS LUNG CANCER UP
ST TUMOR NECROSIS FACTOR PATHWAY
ZHOU INFLAMMATORY RESPONSE FIMA UP
SENESE HDAC2 TARGETS UP
CHASSOT SKIN WOUND
TIAN TNF SIGNALING VIA NFKB
KEGG SYSTEMIC LUPUS ERYTHEMATOSUS
ABE VEGFA TARGETS 2HR
KEGG APOPTOSIS
CORUM NFKB1-NFKB2-REL-RELA-RELB COMPLEX
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
AMIT DELAYED EARLY GENES
HUANG DASATINIB RESISTANCE UP
AMIT EGF RESPONSE 60 MCF10A
HINATA NFKB TARGETS FIBROBLAST UP
WONG ENDMETRIUM CANCER DN
NOJIMA SFRP2 TARGETS UP
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
CHEN HOXA5 TARGETS 6HR UP
MISSIAGLIA REGULATED BY METHYLATION UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
CHEN LVAD SUPPORT OF FAILING HEART DN
DORN ADENOVIRUS INFECTION 32HR DN
CROONQUIST STROMAL STIMULATION UP
SA MMP CYTOKINE CONNECTION
HALMOS CEBPA TARGETS UP
WU CELL MIGRATION
SAGIV CD24 TARGETS DN
KHETCHOUMIAN TRIM24 TARGETS UP
KEGG MAPK SIGNALING PATHWAY
KIM LRRC3B TARGETS
HORIUCHI WTAP TARGETS UP
ONDER CDH1 SIGNALING VIA CTNNB1
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
NETPATH IL 4 PATHWAY DOWN
WOO LIVER CANCER RECURRENCE UP
MAHADEVAN RESPONSE TO MP470 DN
RUTELLA RESPONSE TO CSF2RB AND IL4 DN
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS CDC25 DN
BROWNE HCMV INFECTION 30MIN UP
RIGGI EWING SARCOMA PROGENITOR UP
NCI LYSOPHOSPHOLIPID PATHWAY
BUDHU LIVER CANCER METASTASIS DN
HARRIS HYPOXIA
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
RUIZ TNC TARGETS DN
SEIKE LUNG CANCER POOR SURVIVAL
MUELLER METHYLATED IN GLIOBLASTOMA
KAN RESPONSE TO ARSENIC TRIOXIDE
BASSO CD40 SIGNALING UP
TIAN TNF SIGNALING NOT VIA NFKB
NAGASHIMA NRG1 SIGNALING UP
MARZEC IL2 SIGNALING UP
SOUCEK MYC TARGETS
ENK UV RESPONSE EPIDERMIS DN
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
ZERBINI RESPONSE TO SULINDAC UP
BILBAN B CLL LPL DN
SCIAN INVERSED TARGETS OF TP53 AND TP73 DN
WANG ESOPHAGUS CANCER VS NORMAL UP
FRIDMAN SENESCENCE UP
NCI PTP1BPATHWAY
NETPATH B CELL RECEPTOR PATHWAY UP
MAHADEVAN RESPONSE TO MP470 UP
LEE NEURAL CREST STEM CELL DN
FERRARI RESPONSE TO FENRETINIDE UP
BIOCARTA TID PATHWAY
BILD HRAS ONCOGENIC SIGNATURE
LIANG SILENCED BY METHYLATION 2
DAUER STAT3 TARGETS UP
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN DN
KEGG LEISHMANIA INFECTION
RIGGI EWING SARCOMA PROGENITOR DN
AMIT EGF RESPONSE 60 HELA
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN
BERENJENO TRANSFORMED BY RHOA FOREVER DN
MARKS HDAC TARGETS DN
CHEN HOXA5 TARGETS 9HR UP
DAZARD UV RESPONSE CLUSTER G2
MCLACHLAN DENTAL CARIES DN
AMIT SERUM RESPONSE 40 MCF10A
SEKI INFLAMMATORY RESPONSE LPS UP
HELLER HDAC TARGETS SILENCED BY METHYLATION UP
NETPATH EGFR1 PATHWAY UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
LEE RECENT THYMIC EMIGRANT
BIERIE INFLAMMATORY RESPONSE TGFB1
ENGELMANN CANCER PROGENITORS UP
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP
SANA TNF SIGNALING UP
SENESE HDAC1 AND HDAC2 TARGETS UP
WANG METHYLATED IN BREAST CANCER
XU HGF TARGETS INDUCED BY AKT1 6HR
SENESE HDAC1 TARGETS UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
KIM WT1 TARGETS UP
SENESE HDAC3 TARGETS UP
ONDER CDH1 TARGETS 1 DN
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
XU HGF SIGNALING NOT VIA AKT1 6HR
BIOCARTA KERATINOCYTE PATHWAY
JISON SICKLE CELL DISEASE UP
BIOCARTA GRANULOCYTES PATHWAY
NCI NFKAPPABCANONICALPATHWAY
HESS TARGETS OF HOXA9 AND MEIS1 DN
DASU IL6 SIGNALING UP
ELVIDGE HYPOXIA BY DMOG UP
AMIT EGF RESPONSE 120 MCF10A
IIZUKA RECURRENT LIVER CANCER
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
GOUYER TATI TARGETS UP
NETPATH WNT PATHWAY UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
ZUCCHI METASTASIS DN
BERENJENO ROCK SIGNALING NOT VIA RHOA DN
RUTELLA RESPONSE TO HGF UP
PRAMOONJAGO SOX4 TARGETS UP
WATTEL AUTONOMOUS THYROID ADENOMA DN
KIM WT1 TARGETS 8HR UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica p60 bcehrlichia chaffeensis wakullashigella dysenteriaeescherichia coliGeneSet Name
0.00018 0.00006 0.08636 0.00000NETPATH_IL_2_PATHWAY_UP
0.00001 0.00022 0.00030 0.00000NETPATH_IL_1_PATHWAY_UP
0.00000 0.00000 0.01729 0.00129NETPATH_IL_4_PATHWAY_UP
0.00000 0.00000 0.00147 0.00000NETPATH_IL_3_PATHWAY_UP
0.00159 0.00000 0.00014 0.00001NETPATH_IL_5_PATHWAY_UP
0.07282 0.00000 0.00624 0.00785NCI_IL6_7PATHWAY
0.00570 0.00015 0.00112 0.00023NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00009 0.00000 0.05058 0.00028NETPATH_IL_9_PATHWAY_UP
0.00028 0.00004 0.04120 0.00000NETPATH_IL_7_PATHWAY_UP
0.00510 0.00116 0.00067 0.01389GERY_CEBP_TARGETS
0.00891 0.00196 0.00000 0.01874NCI_ATF2_PATHWAY
0.00000 0.00000 0.00000 0.00000NETPATH_IL_6_PATHWAY_UP
0.00003 0.00114 0.19139 0.00002BIOCARTA_IL10_PATHWAY
0.00000 0.00547 0.00252 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.03120 0.00699 0.01398 0.00000BIOCARTA_NFKB_PATHWAY
0.00009 0.00447 0.00316 0.00000MAHAJAN_RESPONSE_TO_IL1A_UP
0.00358 0.00000 0.18538 0.01415LINDGREN_BLADDER_CANCER_CLUSTER_2B
0.15192 0.00013 0.00166 0.01038VARELA_ZMPSTE24_TARGETS_UP
0.14810 0.03586 0.12756 0.03638MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_DN
0.00041 0.01382 0.00017 0.00159CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP
0.02423 0.00000 0.08527 0.00011TENEDINI_MEGAKARYOCYTE_MARKERS
0.00237 0.00000 0.00053 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00008 0.01394 0.00825 0.00000BIOCARTA_IL1R_PATHWAY
0.00671 0.02134 0.19310 0.01145BRUECKNER_TARGETS_OF_MIRLET7A3_DN
0.04185 0.13231 0.17115 0.04442SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_DN
0.00008 0.00001 0.00004 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00000 0.00000 0.00034 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00206 0.10950 0.02164 0.00003NETPATH_IL_1_PATHWAY
0.00036 0.00027 0.00124 0.01124ELVIDGE_HYPOXIA_UP
0.00492 0.01247 0.00648 0.00026IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00031 0.00042 0.00000 0.00000AMIT_EGF_RESPONSE_40_HELA
0.08744 0.01445 0.09633 0.04532NETPATH_TGFBETA_RECEPTOR_PATHWAY_UP
0.14881 0.02739 0.02126 0.03327YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5
0.19121 0.08623 0.10260 0.00480BROWNE_HCMV_INFECTION_10HR_UP
0.03022 0.00032 0.02542 0.00031JEON_SMAD6_TARGETS_UP
0.10630 0.03497 0.00008 0.02480MITSIADES_RESPONSE_TO_APLIDIN_UP
0.00000 0.00174 0.00000 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.11392 0.16376 0.09420 0.00110NUYTTEN_NIPP1_TARGETS_UP
0.00729 0.08132 0.11110 0.00807TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP
0.00000 0.00001 0.00078 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00004 0.00000 0.14227 0.00000MARKEY_RB1_ACUTE_LOF_UP
0.00008 0.00000 0.00096 0.00000KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.19949 0.03040 0.00253 0.00510DAZARD_UV_RESPONSE_CLUSTER_G3
0.02457 0.05349 0.03970 0.00136XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP
0.01364 0.07767 0.15321 0.03704KEGG_TYPE_II_DIABETES_MELLITUS
0.06140 0.00002 0.01483 0.00002OSADA_ASCL1_TARGETS_DN
0.00032 0.00144 0.08521 0.00000NUYTTEN_EZH2_TARGETS_UP
0.00013 0.00000 0.02611 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.01191 0.04386 0.00000 0.02827GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP
0.08583 0.08277 0.05174 0.00285HUANG_FOXA2_TARGETS_UP
0.08331 0.00000 0.12700 0.00200DELYS_THYROID_CANCER_UP
0.19909 0.00000 0.00016 0.00126TSAI_RESPONSE_TO_IONIZING_RADIATION
0.00000 0.00000 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.03733 0.00259 0.14554 0.10906RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN
0.05037 0.18217 0.18706 0.02877WOTTON_RUNX_TARGETS_UP
0.02211 0.04480 0.05435 0.16523DAZARD_UV_RESPONSE_CLUSTER_G4
0.03179 0.14236 0.13915 0.01619NCI_REG_GR_PATHWAY
0.00000 0.00000 0.17156 0.00000REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.09530 0.01648 0.00077 0.00004NCI_NFAT_TFPATHWAY
0.00000 0.00039 0.00006 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.05249 0.00006 0.02436 0.01985RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
0.00004 0.00037 0.00113 0.00046AMIT_EGF_RESPONSE_120_HELA
0.01255 0.01515 0.15704 0.05932BIOCARTA_RANKL_PATHWAY
0.04558 0.00067 0.18421 0.02480DANG_REGULATED_BY_MYC_DN
0.00659 0.00276 0.13279 0.00438NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.01065 0.05265 0.00111 0.00002DAZARD_RESPONSE_TO_UV_NHEK_UP
0.00008 0.00000 0.01598 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.00442 0.01067 0.04655 0.02164WINTER_HYPOXIA_METAGENE
0.10741 0.13241 0.03443 0.00256BROWNE_HCMV_INFECTION_8HR_UP
0.00443 0.00261 0.10594 0.00098GAJATE_RESPONSE_TO_TRABECTEDIN_UP
0.03715 0.00209 0.08581 0.00184NEWMAN_ERCC6_TARGETS_UP
0.02325 0.03294 0.04735 0.00012CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_KPNA3_NFKB2_NFKBIB_REL_IKBKG__NFKB1_NFKBIE_RELB__NFKBIA_RELA_TNIP2
0.00001 0.00028 0.00000 0.01026PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.00001 0.13273 0.00000 0.10160GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.00000 0.00000 0.00236 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.02930 0.00085 0.00349 0.00020TAVOR_CEBPA_TARGETS_UP
0.00000 0.00000 0.04466 0.00000GAURNIER_PSMD4_TARGETS
0.11465 0.04099 0.00666 0.00071SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.14780 0.11655 0.07626 0.00001NETPATH_TNF_ALPHA_PATHWAY_UP
0.00000 0.00020 0.09953 0.00000NCI_IL23PATHWAY
0.00000 0.00012 0.03754 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00004 0.00032 0.00000 0.00083GESERICK_TERT_TARGETS_DN
0.00097 0.00758 0.19222 0.00025NOJIMA_SFRP2_TARGETS_DN
0.05580 0.00363 0.11137 0.06355NETPATH_TGFBETA_RECEPTOR_PATHWAY_DOWN
0.15813 0.00039 0.14239 0.03242CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP
0.00000 0.00009 0.00021 0.00011AMIT_SERUM_RESPONSE_120_MCF10A
0.00673 0.11885 0.00008 0.00014BROWNE_HCMV_INFECTION_2HR_UP
0.00217 0.07444 0.00042 0.00667DORN_ADENOVIRUS_INFECTION_24HR_DN
0.01166 0.06247 0.02440 0.00686NCI_IL1PATHWAY
0.00270 0.01412 0.00000 0.00001SESTO_RESPONSE_TO_UV_C3
0.00000 0.00000 0.00095 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00068 0.00000 0.00055 0.00002BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.00000 0.00022 0.01687 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.13034 0.03452 0.01375 0.00831NCI_P53DOWNSTREAMPATHWAY
0.01794 0.06742 0.03385 0.00003CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_RPL6_RPL30_RPS13_CHUK_DDX3X_NFKB2_NFKBIB_REL_IKBKG_NFKB1_MAP3K8_RELB_GLG1_NFKBIA_RELA_TNIP2__GTF2I
0.06793 0.12305 0.00820 0.15382GENTILE_UV_HIGH_DOSE_DN
0.19773 0.12283 0.00833 0.15123SPIRA_SMOKERS_LUNG_CANCER_UP
0.13679 0.00254 0.01233 0.00026ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00000 0.02576 0.01029 0.00000ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.02576 0.14941 0.04658 0.00293SENESE_HDAC2_TARGETS_UP
0.00892 0.04468 0.00141 0.17603CHASSOT_SKIN_WOUND
0.00000 0.00000 0.00005 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.08370 0.06977 0.00000 0.08323KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS
0.06758 0.10928 0.10317 0.04288ABE_VEGFA_TARGETS_2HR
0.19256 0.00860 0.06788 0.00000KEGG_APOPTOSIS
0.06790 0.02218 0.19006 0.00288CORUM_NFKB1-NFKB2-REL-RELA-RELB_COMPLEX
0.00168 0.00011 0.00154 0.00010LEE_LIVER_CANCER_HEPATOBLAST
0.00000 0.00000 0.00000 0.00003NAGASHIMA_EGF_SIGNALING_UP
0.04380 0.00462 0.00000 0.00082AMIT_DELAYED_EARLY_GENES
0.00000 0.00093 0.16166 0.00046HUANG_DASATINIB_RESISTANCE_UP
0.00000 0.00070 0.00000 0.00000AMIT_EGF_RESPONSE_60_MCF10A
0.00008 0.00151 0.00153 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.09215 0.13483 0.14629 0.11057WONG_ENDMETRIUM_CANCER_DN
0.00304 0.00340 0.00035 0.00018NOJIMA_SFRP2_TARGETS_UP
0.00028 0.00000 0.18018 0.00000CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.02172 0.01388 0.00221 0.13852CHEN_HOXA5_TARGETS_6HR_UP
0.00145 0.00006 0.00484 0.00000MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.00508 0.00000 0.05182 0.01400SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.00000 0.00301 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.05832 0.03472 0.18395 0.19530CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN
0.00471 0.17242 0.00014 0.00003DORN_ADENOVIRUS_INFECTION_32HR_DN
0.01017 0.00000 0.00808 0.00003CROONQUIST_STROMAL_STIMULATION_UP
0.00023 0.00000 0.10485 0.00133SA_MMP_CYTOKINE_CONNECTION
0.00037 0.00175 0.00005 0.00001HALMOS_CEBPA_TARGETS_UP
0.00041 0.00166 0.17065 0.00033WU_CELL_MIGRATION
0.07586 0.00451 0.01026 0.00010SAGIV_CD24_TARGETS_DN
0.01394 0.00000 0.00741 0.02879KHETCHOUMIAN_TRIM24_TARGETS_UP
0.09741 0.00443 0.01671 0.19572KEGG_MAPK_SIGNALING_PATHWAY
0.00041 0.00017 0.07873 0.00004KIM_LRRC3B_TARGETS
0.00038 0.00059 0.00236 0.00002HORIUCHI_WTAP_TARGETS_UP
0.01063 0.02499 0.01233 0.00015ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.02619 0.02715 0.15816 0.01179GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.00040 0.00000 0.16501 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.00000 0.00000 0.05864 0.01595WOO_LIVER_CANCER_RECURRENCE_UP
0.00009 0.08720 0.00000 0.00317MAHADEVAN_RESPONSE_TO_MP470_DN
0.04786 0.00000 0.01423 0.12734RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN
0.01065 0.00022 0.00072 0.00220CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN
0.11754 0.00435 0.00103 0.07149BROWNE_HCMV_INFECTION_30MIN_UP
0.03244 0.01998 0.14472 0.00632RIGGI_EWING_SARCOMA_PROGENITOR_UP
0.10706 0.08711 0.01724 0.09447NCI_LYSOPHOSPHOLIPID_PATHWAY
0.02068 0.01959 0.10833 0.00126BUDHU_LIVER_CANCER_METASTASIS_DN
0.00029 0.00025 0.00501 0.00034HARRIS_HYPOXIA
0.00008 0.00000 0.18893 0.00002FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN
0.02878 0.02669 0.11015 0.00007KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP
0.00299 0.00056 0.00000 0.00002DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.16337 0.00009 0.15051 0.18340RUIZ_TNC_TARGETS_DN
0.01385 0.00714 0.08149 0.00018SEIKE_LUNG_CANCER_POOR_SURVIVAL
0.01619 0.00332 0.13134 0.19250MUELLER_METHYLATED_IN_GLIOBLASTOMA
0.00121 0.01034 0.02489 0.02558KAN_RESPONSE_TO_ARSENIC_TRIOXIDE
0.00003 0.00000 0.00004 0.00000BASSO_CD40_SIGNALING_UP
0.00078 0.00264 0.00005 0.00702TIAN_TNF_SIGNALING_NOT_VIA_NFKB
0.00000 0.00000 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.00008 0.00004 0.00321 0.00002MARZEC_IL2_SIGNALING_UP
0.00008 0.00027 0.02047 0.00037SOUCEK_MYC_TARGETS
0.04266 0.04439 0.00875 0.02283ENK_UV_RESPONSE_EPIDERMIS_DN
0.00004 0.01086 0.11301 0.05842TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.12784 0.11589 0.07968 0.02814ZERBINI_RESPONSE_TO_SULINDAC_UP
0.00101 0.00005 0.00008 0.14289BILBAN_B_CLL_LPL_DN
0.07987 0.17802 0.02516 0.00384SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN
0.06088 0.00010 0.12426 0.00496WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP
0.13847 0.00628 0.08918 0.00001FRIDMAN_SENESCENCE_UP
0.01749 0.03537 0.09041 0.00089NCI_PTP1BPATHWAY
0.09144 0.00122 0.09708 0.00228NETPATH_B_CELL_RECEPTOR_PATHWAY_UP
0.00000 0.00001 0.06328 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.04779 0.17369 0.12704 0.02158LEE_NEURAL_CREST_STEM_CELL_DN
0.00050 0.00156 0.00712 0.00016FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.19083 0.00829 0.02606 0.00058BIOCARTA_TID_PATHWAY
0.00000 0.00024 0.00000 0.00000BILD_HRAS_ONCOGENIC_SIGNATURE
0.00000 0.00000 0.00396 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.02597 0.00307 0.00005 0.00003DAUER_STAT3_TARGETS_UP
0.00005 0.00466 0.06512 0.00000ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN
0.01693 0.00000 0.00317 0.00028KEGG_LEISHMANIA_INFECTION
0.00264 0.18462 0.02949 0.03627RIGGI_EWING_SARCOMA_PROGENITOR_DN
0.00028 0.00102 0.00007 0.00523AMIT_EGF_RESPONSE_60_HELA
0.06783 0.03269 0.00827 0.08973ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN
0.00060 0.00358 0.00170 0.00016BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.00724 0.00632 0.08234 0.00070MARKS_HDAC_TARGETS_DN
0.00074 0.00291 0.00000 0.00050CHEN_HOXA5_TARGETS_9HR_UP
0.01385 0.00111 0.00032 0.00004DAZARD_UV_RESPONSE_CLUSTER_G2
0.00014 0.00000 0.02949 0.00002MCLACHLAN_DENTAL_CARIES_DN
0.00004 0.00005 0.00000 0.00142AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.01760 0.06950 0.00236 0.15460HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP
0.00205 0.03402 0.00148 0.00008NETPATH_EGFR1_PATHWAY_UP
0.00030 0.00003 0.00003 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00226 0.01806 0.00146 0.08735CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.00000 0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.09721 0.03366 0.14727 0.17730LEE_RECENT_THYMIC_EMIGRANT
0.02071 0.02732 0.05553 0.01522BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.13315 0.01538 0.12755 0.00403ENGELMANN_CANCER_PROGENITORS_UP
0.01041 0.06472 0.00000 0.01185BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
0.00000 0.00000 0.00530 0.00000SANA_TNF_SIGNALING_UP
0.00026 0.01080 0.00255 0.00002SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.00032 0.05272 0.10922 0.00010WANG_METHYLATED_IN_BREAST_CANCER
0.02068 0.00223 0.07814 0.00014XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR
0.00109 0.03717 0.02245 0.00079SENESE_HDAC1_TARGETS_UP
0.00006 0.00004 0.00000 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00000 0.00017 0.00000 0.00002KIM_WT1_TARGETS_UP
0.00039 0.02396 0.02950 0.00076SENESE_HDAC3_TARGETS_UP
0.01007 0.13248 0.09552 0.00021ONDER_CDH1_TARGETS_1_DN
0.00000 0.00336 0.00000 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.02133 0.00063 0.00031 0.00132XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR
0.14087 0.05653 0.00147 0.02283BIOCARTA_KERATINOCYTE_PATHWAY
0.00209 0.00000 0.07115 0.00023JISON_SICKLE_CELL_DISEASE_UP
0.00695 0.00012 0.18726 0.15379BIOCARTA_GRANULOCYTES_PATHWAY
0.04547 0.02559 0.03623 0.00009NCI_NFKAPPABCANONICALPATHWAY
0.00004 0.00000 0.00054 0.08966HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00020 0.03956 0.00099 0.00015DASU_IL6_SIGNALING_UP
0.00017 0.00131 0.00078 0.01098ELVIDGE_HYPOXIA_BY_DMOG_UP
0.00028 0.03134 0.02002 0.00004AMIT_EGF_RESPONSE_120_MCF10A
0.03196 0.01342 0.12265 0.02641IIZUKA_RECURRENT_LIVER_CANCER
0.00000 0.00009 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.01389 0.06016 0.05947 0.03224GOUYER_TATI_TARGETS_UP
0.15536 0.17499 0.00273 0.00227NETPATH_WNT_PATHWAY_UP
0.00000 0.00265 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.05022 0.00899 0.00013 0.00000ZUCCHI_METASTASIS_DN
0.01317 0.12832 0.01384 0.01676BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN
0.05386 0.00473 0.10389 0.00005RUTELLA_RESPONSE_TO_HGF_UP
0.00119 0.00099 0.00000 0.00005PRAMOONJAGO_SOX4_TARGETS_UP
0.00697 0.01382 0.00132 0.02507WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN
0.01140 0.07001 0.00229 0.07735KIM_WT1_TARGETS_8HR_UP
0.00000 0.00107 0.00000 0.02690PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN