BICLUSTER_ID : UPREG-402
PATHOGENS /2/ : streptococcus pneumoniae,yersinia enterocolitica
TARGETS /5/ : IL6, PTGS2, JUN, BCL2, CCL8
Gene SetLeading Edge Genes
NETPATH IL 7 PATHWAY UPCXCL1, BCL2, JUN, CCL8, CXCL2
NETPATH TNF ALPHA PATHWAY DOWNREL, CXCL1, JUN, JUNB, TIPARP, MAFF, IL6, GEM, EGR1, DUSP2, PTGS2, TNFAIP3, ZFP36, CXCL2, BHLHB2
NETPATH IL 6 PATHWAY UPGADD45B, CXCL1, JUN, JUNB, MAP3K8, MAFF, SOCS1, ZFP36, BHLHB2
NOJIMA SFRP2 TARGETS UP
CHEN HOXA5 TARGETS 6HR UP
JI METASTASIS REPRESSED BY STK11
KONDO PROSTATE CANCER WITH H3K27ME3
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
LINDSTEDT DENDRITIC CELL MATURATION B
CROONQUIST STROMAL STIMULATION UP
SAKAI CHRONIC HEPATITIS VS LIVER CANCER DN
SIMBULAN UV RESPONSE NORMAL UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
ONDER CDH1 SIGNALING VIA CTNNB1
AMIT EGF RESPONSE 40 HELA
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
MAHADEVAN RESPONSE TO MP470 DN
TIAN TNF SIGNALING NOT VIA NFKB
AMIT EGF RESPONSE 240 MCF10A
NAGASHIMA NRG1 SIGNALING UP
AMIT SERUM RESPONSE 60 MCF10A
ZERBINI RESPONSE TO SULINDAC UP
DIRMEIER LMP1 RESPONSE EARLY
GENTILE UV LOW DOSE DN
DAZARD UV RESPONSE CLUSTER G4
KEGG INTESTINAL IMMUNE NETWORK FOR IGA PRODUCTION
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
FERRARI RESPONSE TO FENRETINIDE UP
BILD HRAS ONCOGENIC SIGNATURE
NCI NFAT TFPATHWAY
ONDER CDH1 TARGETS 3 DN
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
DAZARD RESPONSE TO UV NHEK UP
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2
AMIT EGF RESPONSE 60 HELA
TESAR ALK TARGETS HUMAN ES 4D DN
DAZARD UV RESPONSE CLUSTER G2
AMIT SERUM RESPONSE 40 MCF10A
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
BIERIE INFLAMMATORY RESPONSE TGFB1
GESERICK TERT TARGETS DN
WANG METHYLATED IN BREAST CANCER
AMIT SERUM RESPONSE 120 MCF10A
BROWNE HCMV INFECTION 2HR UP
BIOCARTA ASBCELL PATHWAY
REACTOME GAP JUNCTION ASSEMBLY
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
AMIT EGF RESPONSE 40 MCF10A
REACTOME G ALPHA I SIGNALLING EVENTS
LIAN LIPA TARGETS 3M
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
KOBAYASHI EGFR SIGNALING 6HR DN
AMIT EGF RESPONSE 120 MCF10A
CHASSOT SKIN WOUND
REACTOME GPCR LIGAND BINDING
TIAN TNF SIGNALING VIA NFKB
MURAKAMI UV RESPONSE 1HR DN
GENTILE UV LOW DOSE UP
ZUCCHI METASTASIS DN
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
PRAMOONJAGO SOX4 TARGETS UP
KRIGE AMINO ACID DEPRIVATION
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bl6yersinia enterocolitica p60 bcstreptococcus pneumoniae d39GeneSet Name
0.00623 0.00028 0.04346NETPATH_IL_7_PATHWAY_UP
0.00024 0.00000 0.10568NETPATH_TNF_ALPHA_PATHWAY_DOWN
0.00000 0.00000 0.09713NETPATH_IL_6_PATHWAY_UP
0.00172 0.00304 0.00013NOJIMA_SFRP2_TARGETS_UP
0.03187 0.02172 0.01993CHEN_HOXA5_TARGETS_6HR_UP
0.16372 0.02414 0.01046JI_METASTASIS_REPRESSED_BY_STK11
0.03667 0.05800 0.03005KONDO_PROSTATE_CANCER_WITH_H3K27ME3
0.00026 0.00417 0.04229REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS
0.00006 0.00005 0.06867REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.04571 0.00237 0.12766LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.04761 0.01017 0.04326CROONQUIST_STROMAL_STIMULATION_UP
0.02304 0.04185 0.01261SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_DN
0.11226 0.04892 0.11717SIMBULAN_UV_RESPONSE_NORMAL_UP
0.05090 0.00492 0.17044IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.05101 0.01063 0.08160ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.01474 0.00031 0.00001AMIT_EGF_RESPONSE_40_HELA
0.01516 0.02619 0.10589GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.00031 0.00009 0.00298MAHADEVAN_RESPONSE_TO_MP470_DN
0.01664 0.00078 0.00054TIAN_TNF_SIGNALING_NOT_VIA_NFKB
0.17038 0.00014 0.09798AMIT_EGF_RESPONSE_240_MCF10A
0.00002 0.00000 0.00006NAGASHIMA_NRG1_SIGNALING_UP
0.00000 0.00000 0.00074AMIT_SERUM_RESPONSE_60_MCF10A
0.13677 0.12784 0.10474ZERBINI_RESPONSE_TO_SULINDAC_UP
0.00000 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.06577 0.01983 0.16267GENTILE_UV_LOW_DOSE_DN
0.01169 0.02211 0.16255DAZARD_UV_RESPONSE_CLUSTER_G4
0.10664 0.13189 0.08474KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION
0.00002 0.00000 0.05768REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.00508 0.00050 0.11268FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00208 0.00000 0.16121BILD_HRAS_ONCOGENIC_SIGNATURE
0.06500 0.09530 0.02419NCI_NFAT_TFPATHWAY
0.00150 0.00099 0.02816ONDER_CDH1_TARGETS_3_DN
0.00077 0.00004 0.00000AMIT_EGF_RESPONSE_120_HELA
0.05660 0.02597 0.16214DAUER_STAT3_TARGETS_UP
0.08717 0.01065 0.03803DAZARD_RESPONSE_TO_UV_NHEK_UP
0.09646 0.02325 0.10714CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_KPNA3_NFKB2_NFKBIB_REL_IKBKG__NFKB1_NFKBIE_RELB__NFKBIA_RELA_TNIP2
0.02663 0.00028 0.00040AMIT_EGF_RESPONSE_60_HELA
0.18854 0.19047 0.03208TESAR_ALK_TARGETS_HUMAN_ES_4D_DN
0.11521 0.01385 0.00031DAZARD_UV_RESPONSE_CLUSTER_G2
0.00000 0.00004 0.00000AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.00000 0.00548SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.11854GAURNIER_PSMD4_TARGETS
0.00000 0.00000 0.01862ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.07716 0.02071 0.16336BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.00141 0.00004 0.00000GESERICK_TERT_TARGETS_DN
0.00217 0.00032 0.09053WANG_METHYLATED_IN_BREAST_CANCER
0.00013 0.00000 0.00824AMIT_SERUM_RESPONSE_120_MCF10A
0.06014 0.00673 0.16198BROWNE_HCMV_INFECTION_2HR_UP
0.04816 0.13527 0.06575BIOCARTA_ASBCELL_PATHWAY
0.10149 0.04558 0.09126REACTOME_GAP_JUNCTION_ASSEMBLY
0.00080 0.00006 0.02392HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00757 0.00270 0.00028SESTO_RESPONSE_TO_UV_C3
0.07508 0.03705 0.01077AMIT_EGF_RESPONSE_40_MCF10A
0.02054 0.01232 0.14460REACTOME_G_ALPHA_I_SIGNALLING_EVENTS
0.01061 0.01896 0.16263LIAN_LIPA_TARGETS_3M
0.00000 0.00000 0.00005UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.12191 0.11776 0.01383KOBAYASHI_EGFR_SIGNALING_6HR_DN
0.02376 0.00028 0.00088AMIT_EGF_RESPONSE_120_MCF10A
0.13170 0.00892 0.00000CHASSOT_SKIN_WOUND
0.00645 0.01878 0.04745REACTOME_GPCR_LIGAND_BINDING
0.00000 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.01085 0.06783 0.00252MURAKAMI_UV_RESPONSE_1HR_DN
0.05500 0.01341 0.16174GENTILE_UV_LOW_DOSE_UP
0.08451 0.05022 0.10715ZUCCHI_METASTASIS_DN
0.00139 0.00168 0.08457LEE_LIVER_CANCER_HEPATOBLAST
0.00000 0.00000 0.00000NAGASHIMA_EGF_SIGNALING_UP
0.02502 0.00119 0.00813PRAMOONJAGO_SOX4_TARGETS_UP
0.09096 0.01120 0.04793KRIGE_AMINO_ACID_DEPRIVATION
0.00000 0.00000 0.00000AMIT_EGF_RESPONSE_60_MCF10A