BICLUSTER_ID : UPREG-428
PATHOGENS /3/ : yersinia enterocolitica,helicobacter pylori,burkholderia pseudomallei
TARGETS /5/ : CCL20, PTGS2, HMOX1, CCL2, GLA
Gene SetLeading Edge Genes
NETPATH IL 4 PATHWAY DOWNCCL20, PTGS2, CCL2, CXCL2
GERY CEBP TARGETSHMOX1, CXCL1, HBEGF, GLA, GADD45G, TNFAIP6, ATF3, IFRD1, DUSP1, PTX3
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
NOJIMA SFRP2 TARGETS UP
CHEN HOXA5 TARGETS 6HR UP
MISSIAGLIA REGULATED BY METHYLATION UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
BILD HRAS ONCOGENIC SIGNATURE
ONDER CDH1 TARGETS 3 DN
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
DAUER STAT3 TARGETS UP
MAHAJAN RESPONSE TO IL1A UP
BIOCARTA EPONFKB PATHWAY
LIAN LIPA TARGETS 6M
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS
MENSE HYPOXIA UP
AUJLA IL22 AND IL17A SIGNALING
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
DAZARD UV RESPONSE CLUSTER G2
CHEN HOXA5 TARGETS 9HR UP
SA MMP CYTOKINE CONNECTION
RASHI RESPONSE TO IONIZING RADIATION 2
AMIT SERUM RESPONSE 40 MCF10A
LINDSTEDT DENDRITIC CELL MATURATION A
SEKI INFLAMMATORY RESPONSE LPS UP
ELVIDGE HYPOXIA UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
BROWNE HCMV INFECTION 4HR UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
GESERICK TERT TARGETS DN
BROWNE HCMV INFECTION 2HR UP
MAHADEVAN RESPONSE TO MP470 DN
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
HARRIS HYPOXIA
VERHAAK AML WITH NPM1 MUTATED UP
KEGG LINOLEIC ACID METABOLISM
LIAN LIPA TARGETS 3M
GEISS RESPONSE TO DSRNA UP
HINATA NFKB TARGETS KERATINOCYTE UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
GENTILE UV HIGH DOSE UP
BIOCARTA CYTOKINE PATHWAY
KOBAYASHI EGFR SIGNALING 6HR DN
ELVIDGE HYPOXIA BY DMOG UP
AMIT EGF RESPONSE 120 MCF10A
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
DUTTA APOPTOSIS VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
ZERBINI RESPONSE TO SULINDAC UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
NAGASHIMA EGF SIGNALING UP
DIRMEIER LMP1 RESPONSE EARLY
WOTTON RUNX TARGETS UP
MAHADEVAN RESPONSE TO MP470 UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
HINATA NFKB TARGETS FIBROBLAST UP
FERRARI RESPONSE TO FENRETINIDE UP
AMIT EGF RESPONSE 60 MCF10A
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
burkholderia pseudomalleiyersinia enterocolitica p60 bl6helicobacter pylori kx1 npgecGeneSet Name
0.16712 0.00146 0.00644NETPATH_IL_4_PATHWAY_DOWN
0.00015 0.00040 0.04422GERY_CEBP_TARGETS
0.02392 0.00000 0.06985KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00000 0.00037 0.01127NOJIMA_SFRP2_TARGETS_UP
0.01125 0.01499 0.08749CHEN_HOXA5_TARGETS_6HR_UP
0.00964 0.00038 0.00255MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.01050 0.00000 0.09695OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.01123 0.00000 0.16783BILD_HRAS_ONCOGENIC_SIGNATURE
0.05647 0.00026 0.06938ONDER_CDH1_TARGETS_3_DN
0.00002 0.00021 0.18497GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00256 0.06189 0.01934DAUER_STAT3_TARGETS_UP
0.01913 0.00010 0.00083MAHAJAN_RESPONSE_TO_IL1A_UP
0.19387 0.15613 0.04104BIOCARTA_EPONFKB_PATHWAY
0.04822 0.00177 0.05227LIAN_LIPA_TARGETS_6M
0.09854 0.00794 0.01155REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS
0.00659 0.17416 0.00732MENSE_HYPOXIA_UP
0.14966 0.00953 0.04599AUJLA_IL22_AND_IL17A_SIGNALING
0.05958 0.00054 0.00213REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.02586 0.01250 0.15355DAZARD_UV_RESPONSE_CLUSTER_G2
0.03571 0.00807 0.00899CHEN_HOXA5_TARGETS_9HR_UP
0.13793 0.01474 0.13965SA_MMP_CYTOKINE_CONNECTION
0.16626 0.00297 0.10813RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.06818 0.00000 0.13910AMIT_SERUM_RESPONSE_40_MCF10A
0.00750 0.00029 0.00003LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.01261 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.02727 0.00031 0.11617ELVIDGE_HYPOXIA_UP
0.00000 0.00398 0.00796GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.02223 0.00019 0.06493BROWNE_HCMV_INFECTION_4HR_UP
0.00139 0.00000 0.00002ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.09871 0.00563 0.00098IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00290 0.00021 0.12195AMIT_EGF_RESPONSE_40_HELA
0.00623 0.00000 0.01048GESERICK_TERT_TARGETS_DN
0.05164 0.00222 0.02678BROWNE_HCMV_INFECTION_2HR_UP
0.00025 0.00072 0.09518MAHADEVAN_RESPONSE_TO_MP470_DN
0.00000 0.00030 0.06147HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.16949 0.00029 0.08612HARRIS_HYPOXIA
0.13600 0.00000 0.06454VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.02282 0.10816 0.11971KEGG_LINOLEIC_ACID_METABOLISM
0.03580 0.00252 0.09060LIAN_LIPA_TARGETS_3M
0.11502 0.00109 0.00002GEISS_RESPONSE_TO_DSRNA_UP
0.00143 0.00000 0.00256HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00019 0.00000 0.00603UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00974 0.04436 0.12131GENTILE_UV_HIGH_DOSE_UP
0.13358 0.00009 0.15912BIOCARTA_CYTOKINE_PATHWAY
0.01348 0.04783 0.10830KOBAYASHI_EGFR_SIGNALING_6HR_DN
0.03396 0.00028 0.06336ELVIDGE_HYPOXIA_BY_DMOG_UP
0.05040 0.00086 0.19126AMIT_EGF_RESPONSE_120_MCF10A
0.03675 0.00018 0.00009SOUCEK_MYC_TARGETS
0.00000 0.00016 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.07914 0.00201 0.05736DUTTA_APOPTOSIS_VIA_NFKB
0.00000 0.00037 0.00039GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.11717 0.05840 0.06538ZERBINI_RESPONSE_TO_SULINDAC_UP
0.02880 0.00000 0.10013OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00000 0.00000 0.01564NAGASHIMA_EGF_SIGNALING_UP
0.04849 0.00018 0.06932DIRMEIER_LMP1_RESPONSE_EARLY
0.19046 0.04686 0.19024WOTTON_RUNX_TARGETS_UP
0.14983 0.00018 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.01688 0.02844 0.00004PRAMOONJAGO_SOX4_TARGETS_UP
0.09787 0.00000 0.15432PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.03538 0.00034 0.05134HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.05896 0.01472 0.11271FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00375 0.00000 0.04711AMIT_EGF_RESPONSE_60_MCF10A
0.10469 0.00012 0.00000REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES