BICLUSTER_ID : UPREG-432
PATHOGENS /2/ : yersinia enterocolitica,helicobacter pylori
TARGETS /8/ : LCN2, JUN, HMOX1, CCL2, IL6, GCH1, PTGS2, PIM1
Gene SetLeading Edge Genes
NETPATH IL 1 PATHWAY UPCSF3, LCN2, LIF, JUN, CXCL1, PLK2, CCL2, HBEGF, CCL7, IL6, PTGS2, CXCL2, PTX3
GERY CEBP TARGETSGADD45B, LCN2, HMOX1, CXCL1, JUNB, HBEGF, MYD116, GCH1, IFRD1, PIM1, MAFK
NETPATH IL 9 PATHWAY UPCCL7, LCN2, CCL2, JUNB, PIM1
NETPATH IL 6 PATHWAY UPMAFF, GADD45B, CXCL1, JUN, JUNB, PIM1, HBEGF, MAP3K8
NOJIMA SFRP2 TARGETS UP
CHEN HOXA5 TARGETS 6HR UP
NCI VWF INTERACTION WITH COLLAGEN
ONDER CDH1 TARGETS 3 DN
LEONARD HYPOXIA
BIOCARTA STEM PATHWAY
DAUER STAT3 TARGETS UP
MAHAJAN RESPONSE TO IL1A UP
NCI CHEMOKINE RECEPTORS BIND CHEMOKINES
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
KEGG GRAFT VERSUS HOST DISEASE
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS
WEBER METHYLATED LCP IN SPERM UP
AUJLA IL22 AND IL17A SIGNALING
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
CHEN HOXA5 TARGETS 9HR UP
LINDSTEDT DENDRITIC CELL MATURATION B
RAY ALZHEIMERS DISEASE
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS
ELVIDGE HYPOXIA UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
COATES MACROPHAGE M1 VS M2 DN
BIERIE INFLAMMATORY RESPONSE TGFB1
GESERICK TERT TARGETS DN
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE
MAHADEVAN RESPONSE TO MP470 DN
BROWNE HCMV INFECTION 2HR UP
HARRIS HYPOXIA
HINATA NFKB TARGETS KERATINOCYTE UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
KOBAYASHI EGFR SIGNALING 6HR DN
AMIT EGF RESPONSE 20 HELA
BIOCARTA GRANULOCYTES PATHWAY
WEBER METHYLATED LCP IN FIBROBLAST UP
SU KIDNEY
MURATA VIRULENCE OF H PILORI
ELVIDGE HYPOXIA BY DMOG UP
NAGASHIMA NRG1 SIGNALING UP
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
DUTTA APOPTOSIS VIA NFKB
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 3
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
KRIGE AMINO ACID DEPRIVATION
PRAMOONJAGO SOX4 TARGETS UP
SEMENZA HIF1 TARGETS
CORUM ETS2-FOS-JUN COMPLEX
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bl6helicobacter pylori kx2 npgecyersinia enterocolitica p60 bl6GeneSet Name
0.00024 0.08273 0.00000NETPATH_IL_1_PATHWAY_UP
0.00277 0.14043 0.00040GERY_CEBP_TARGETS
0.00016 0.03276 0.00016NETPATH_IL_9_PATHWAY_UP
0.00000 0.13630 0.00000NETPATH_IL_6_PATHWAY_UP
0.00172 0.03559 0.00037NOJIMA_SFRP2_TARGETS_UP
0.03187 0.18281 0.01499CHEN_HOXA5_TARGETS_6HR_UP
0.15144 0.03014 0.16999NCI_VWF_INTERACTION_WITH_COLLAGEN
0.00150 0.07857 0.00026ONDER_CDH1_TARGETS_3_DN
0.08551 0.00289 0.01346LEONARD_HYPOXIA
0.00467 0.08374 0.03650BIOCARTA_STEM_PATHWAY
0.05660 0.04938 0.06189DAUER_STAT3_TARGETS_UP
0.00113 0.05579 0.00010MAHAJAN_RESPONSE_TO_IL1A_UP
0.04689 0.10173 0.01398NCI_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.10871 0.11321 0.10917NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.00424 0.09151 0.00069KEGG_GRAFT_VERSUS_HOST_DISEASE
0.00026 0.03582 0.00794REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS
0.07480 0.06026 0.04202WEBER_METHYLATED_LCP_IN_SPERM_UP
0.01525 0.08713 0.00953AUJLA_IL22_AND_IL17A_SIGNALING
0.00006 0.01462 0.00054REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.01506 0.09671 0.00807CHEN_HOXA5_TARGETS_9HR_UP
0.04571 0.00320 0.04591LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.06510 0.14264 0.03429RAY_ALZHEIMERS_DISEASE
0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00011 0.00000GAURNIER_PSMD4_TARGETS
0.07710 0.09295 0.14876REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS
0.00923 0.09761 0.00031ELVIDGE_HYPOXIA_UP
0.00810 0.08415 0.00398GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.01844 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.05090 0.05769 0.00563IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00075 0.14943 0.00342COATES_MACROPHAGE_M1_VS_M2_DN
0.07716 0.03130 0.05248BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.00141 0.01236 0.00000GESERICK_TERT_TARGETS_DN
0.13630 0.18962 0.12402REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE
0.00031 0.09615 0.00072MAHADEVAN_RESPONSE_TO_MP470_DN
0.06014 0.03942 0.00222BROWNE_HCMV_INFECTION_2HR_UP
0.00250 0.01945 0.00029HARRIS_HYPOXIA
0.00000 0.16190 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00000 0.03267 0.00000UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.12191 0.10019 0.04783KOBAYASHI_EGFR_SIGNALING_6HR_DN
0.16753 0.11482 0.18824AMIT_EGF_RESPONSE_20_HELA
0.03005 0.01885 0.01449BIOCARTA_GRANULOCYTES_PATHWAY
0.13687 0.04990 0.09238WEBER_METHYLATED_LCP_IN_FIBROBLAST_UP
0.09043 0.03000 0.06464SU_KIDNEY
0.05736 0.19213 0.05814MURATA_VIRULENCE_OF_H_PILORI
0.01114 0.05588 0.00028ELVIDGE_HYPOXIA_BY_DMOG_UP
0.00002 0.08878 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.00000 0.01521 0.00018SOUCEK_MYC_TARGETS
0.00000 0.00000 0.00016TIAN_TNF_SIGNALING_VIA_NFKB
0.00646 0.03297 0.00201DUTTA_APOPTOSIS_VIA_NFKB
0.00024 0.01942 0.00037GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00869 0.14313 0.12161YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_3
0.08451 0.03486 0.04370ZUCCHI_METASTASIS_DN
0.00000 0.01745 0.00000NAGASHIMA_EGF_SIGNALING_UP
0.00000 0.14826 0.00018DIRMEIER_LMP1_RESPONSE_EARLY
0.00025 0.00810 0.00018MAHADEVAN_RESPONSE_TO_MP470_UP
0.09096 0.04170 0.01090KRIGE_AMINO_ACID_DEPRIVATION
0.02502 0.00069 0.02844PRAMOONJAGO_SOX4_TARGETS_UP
0.01510 0.00026 0.00609SEMENZA_HIF1_TARGETS
0.11393 0.12452 0.09254CORUM_ETS2-FOS-JUN_COMPLEX
0.03435 0.10685 0.00034HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00000 0.03534 0.00000AMIT_EGF_RESPONSE_60_MCF10A
0.00002 0.00042 0.00012REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES