BICLUSTER_ID : UPREG-44
PATHOGENS /6/ : pseudomonas aeruginosa,listeria monocytogenes,bifidobacterium bifidum,yersinia enterocolitica,helicobacter pylori,ehrlichia chaffeensis
TARGETS /0/ :
Gene SetLeading Edge Genes
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
LEONARD HYPOXIA
WEINMANN ADAPTATION TO HYPOXIA DN
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
CROONQUIST STROMAL STIMULATION UP
LINDSTEDT DENDRITIC CELL MATURATION B
LEE LIVER CANCER MYC TGFA UP
BIOCARTA IL1R PATHWAY
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
WALLACE PROSTATE CANCER RACE UP
HORIUCHI WTAP TARGETS UP
AMIT EGF RESPONSE 40 HELA
NETPATH IL 7 PATHWAY UP
NETPATH IL 4 PATHWAY DOWNGADD45B, CXCL2
UROSEVIC RESPONSE TO IMIQUIMOD
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS CDC25 DN
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
BROWNE INTERFERON RESPONSIVE GENES
KEGG JAK STAT SIGNALING PATHWAY
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
NETPATH KIT RECEPTOR PATHWAY UP
HARRIS HYPOXIA
DER IFN BETA RESPONSE UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
HINATA NFKB TARGETS KERATINOCYTE UP
MARKEY RB1 ACUTE LOF UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
MARZEC IL2 SIGNALING UP
NAGASHIMA NRG1 SIGNALING UP
SOUCEK MYC TARGETS
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
ZERBINI RESPONSE TO SULINDAC UP
DIRMEIER LMP1 RESPONSE EARLY
KEGG INTESTINAL IMMUNE NETWORK FOR IGA PRODUCTION
MAHADEVAN RESPONSE TO MP470 UP
FERRARI RESPONSE TO FENRETINIDE UP
BILD HRAS ONCOGENIC SIGNATURE
ZHOU INFLAMMATORY RESPONSE LIVE UP
ONDER CDH1 TARGETS 3 DN
NETPATH IL 3 PATHWAY UP
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
DEBOSSCHER NFKB TARGETS REPRESSED BY GLUCOCORTICOIDS
LIANG SILENCED BY METHYLATION 2
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
KEGG LEISHMANIA INFECTION
NETPATH IL 6 PATHWAY UPGADD45B, CXCL1, JUNB, MAP3K8
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
DER IFN ALPHA RESPONSE UP
MCLACHLAN DENTAL CARIES UP
WU HBX TARGETS 1 UP
PODAR RESPONSE TO ADAPHOSTIN UP
CHEN HOXA5 TARGETS 9HR UP
DAZARD UV RESPONSE CLUSTER G2
NETPATH IL 5 PATHWAY UPPLSCR1
MCLACHLAN DENTAL CARIES DN
LEE LIVER CANCER E2F1 UP
FOSTER INFLAMMATORY RESPONSE LPS DN
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
HELLER SILENCED BY METHYLATION UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHU CMV 8 HR UP
MARKEY RB1 CHRONIC LOF DN
SMID BREAST CANCER LUMINAL B DN
ZHOU INFLAMMATORY RESPONSE LPS UP
NCI IL23PATHWAYCXCL1
BIOCARTA INFLAM PATHWAY
SANA TNF SIGNALING UP
NCI IL27PATHWAY
SENESE HDAC1 AND HDAC2 TARGETS UP
FOSTER INFLAMMATORY RESPONSE LPS UP
AMIT SERUM RESPONSE 120 MCF10A
ONDER CDH1 TARGETS 2 DN
NCI IL1PATHWAY
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 2
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
GEISS RESPONSE TO DSRNA UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1
GERY CEBP TARGETSGADD45B, IFRD1, CXCL1
NCI IL12 2PATHWAY
TIAN TNF SIGNALING VIA NFKB
ZHU CMV ALL UP
NETPATH IL 2 PATHWAY UP
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
NETPATH IL 1 PATHWAY UPCXCL1, CXCL2
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bl6helicobacter pylori kx1 mgepyersinia enterocolitica p60 bl6listeria monocytogenesbifidobacterium bifidumehrlichia chaffeensis libertyehrlichia chaffeensis wakullapseudomonas aeruginosa fdr440GeneSet Name
0.10433 0.10553 0.00176 0.00002 0.01383 0.04577 0.00000 0.00001CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.00000 0.02218 0.00000 0.02915 0.00000 0.00077 0.00000 0.00195KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00000 0.00008 0.00000 0.00001 0.01391 0.09755 0.00301 0.00010OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.05054 0.07692 0.02220 0.00015 0.08510 0.00642 0.00000 0.01991SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.00000 0.03509 0.00021 0.00023 0.00214 0.01105 0.00547 0.01700GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.08551 0.00002 0.01346 0.00328 0.00822 0.02395 0.00008 0.00131LEONARD_HYPOXIA
0.00024 0.07109 0.00006 0.01186 0.01898 0.11374 0.04046 0.01567WEINMANN_ADAPTATION_TO_HYPOXIA_DN
0.00000 0.02414 0.00011 0.00001 0.00000 0.00000 0.00000 0.00068ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.04761 0.03674 0.00954 0.05925 0.01386 0.00903 0.00000 0.00017CROONQUIST_STROMAL_STIMULATION_UP
0.04571 0.00000 0.04591 0.00437 0.00000 0.02223 0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.08847 0.11284 0.02194 0.00938 0.13364 0.02710 0.00000 0.06140LEE_LIVER_CANCER_MYC_TGFA_UP
0.00017 0.00078 0.00114 0.00776 0.01532 0.06455 0.01394 0.06380BIOCARTA_IL1R_PATHWAY
0.00427 0.00000 0.00297 0.04054 0.00098 0.09956 0.00001 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00011 0.00015 0.00029 0.00000 0.00005 0.00000 0.00000 0.00003LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00001 0.17667 0.00029 0.00031 0.00167 0.00000 0.00000 0.15257WALLACE_PROSTATE_CANCER_RACE_UP
0.00735 0.02539 0.01137 0.01805 0.00296 0.01757 0.00059 0.00881HORIUCHI_WTAP_TARGETS_UP
0.01474 0.00125 0.00021 0.00068 0.00190 0.15480 0.00042 0.15015AMIT_EGF_RESPONSE_40_HELA
0.00623 0.00294 0.00709 0.09197 0.01764 0.00005 0.00004 0.00003NETPATH_IL_7_PATHWAY_UP
0.00145 0.00002 0.00146 0.00001 0.00103 0.00340 0.00000 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.00114 0.19498 0.00167 0.00008 0.00005 0.00027 0.00001 0.00512UROSEVIC_RESPONSE_TO_IMIQUIMOD
0.07134 0.09986 0.00504 0.07558 0.11419 0.00580 0.00022 0.08542CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN
0.00024 0.00000 0.00184 0.00000 0.07330 0.01294 0.00174 0.00052THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00000 0.07388 0.00006 0.00000 0.00000 0.00000 0.00000 0.00002BROWNE_INTERFERON_RESPONSIVE_GENES
0.00005 0.09614 0.00111 0.17844 0.00000 0.18395 0.00097 0.15521KEGG_JAK_STAT_SIGNALING_PATHWAY
0.01109 0.10179 0.00708 0.00008 0.00139 0.06656 0.00001 0.11741TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.00062 0.00065 0.00015 0.05671 0.08735 0.05936 0.00015 0.18259NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00250 0.00027 0.00029 0.00000 0.05400 0.03906 0.00025 0.00003HARRIS_HYPOXIA
0.04202 0.04581 0.04762 0.00000 0.02261 0.08872 0.00214 0.00222DER_IFN_BETA_RESPONSE_UP
0.05961 0.00015 0.02538 0.00000 0.04303 0.00766 0.00056 0.00448DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.00000 0.00002 0.00000 0.00001 0.00013 0.00058 0.00001 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00200 0.07713 0.01647 0.00004 0.00000 0.00000 0.00000 0.01820MARKEY_RB1_ACUTE_LOF_UP
0.00045 0.00005 0.00058 0.00736 0.00000 0.00966 0.00000 0.00034KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00077 0.00018 0.00020 0.00006 0.00000 0.00000 0.00000BASSO_CD40_SIGNALING_UP
0.00016 0.04862 0.00021 0.00507 0.02397 0.04723 0.00004 0.01502MARZEC_IL2_SIGNALING_UP
0.00002 0.00000 0.00000 0.00045 0.05507 0.00351 0.00000 0.00002NAGASHIMA_NRG1_SIGNALING_UP
0.00000 0.00011 0.00018 0.09270 0.00012 0.00038 0.00027 0.02994SOUCEK_MYC_TARGETS
0.00615 0.01257 0.00356 0.00000 0.00779 0.11368 0.00144 0.00021NUYTTEN_EZH2_TARGETS_UP
0.00646 0.00000 0.00201 0.01422 0.00215 0.00023 0.00000 0.00513DUTTA_APOPTOSIS_VIA_NFKB
0.00017 0.00543 0.00000 0.00142 0.00389 0.08988 0.01086 0.06809TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.13677 0.00318 0.05840 0.05033 0.11328 0.13115 0.11589 0.03840ZERBINI_RESPONSE_TO_SULINDAC_UP
0.00000 0.00157 0.00018 0.00199 0.00294 0.00342 0.00000 0.00002DIRMEIER_LMP1_RESPONSE_EARLY
0.10664 0.16521 0.13918 0.00181 0.00179 0.08853 0.00181 0.03514KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION
0.00025 0.00002 0.00018 0.00004 0.00318 0.00131 0.00001 0.00002MAHADEVAN_RESPONSE_TO_MP470_UP
0.00508 0.00008 0.01472 0.06128 0.05329 0.18558 0.00156 0.00002FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00208 0.00029 0.00000 0.00000 0.00118 0.05938 0.00024 0.00028BILD_HRAS_ONCOGENIC_SIGNATURE
0.00000 0.00000 0.00000 0.00000 0.00000 0.05362 0.00039 0.00010ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.00150 0.00085 0.00026 0.00011 0.01033 0.16184 0.00507 0.00194ONDER_CDH1_TARGETS_3_DN
0.00000 0.03326 0.00000 0.00553 0.01084 0.00030 0.00000 0.15088NETPATH_IL_3_PATHWAY_UP
0.00077 0.00003 0.00029 0.02592 0.00402 0.00639 0.00037 0.00068AMIT_EGF_RESPONSE_120_HELA
0.05660 0.00067 0.06189 0.00016 0.00011 0.06350 0.00307 0.00085DAUER_STAT3_TARGETS_UP
0.19623 0.09299 0.17962 0.09424 0.06366 0.16474 0.16910 0.02560DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS
0.00000 0.00031 0.00000 0.00001 0.00000 0.00000 0.00000 0.00005LIANG_SILENCED_BY_METHYLATION_2
0.03866 0.02466 0.02528 0.00001 0.13644 0.00000 0.00000 0.05763NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.00675 0.00031 0.07814 0.00055 0.00573 0.00000 0.00000 0.00027KEGG_LEISHMANIA_INFECTION
0.00000 0.00236 0.00000 0.00233 0.00007 0.00150 0.00000 0.03716NETPATH_IL_6_PATHWAY_UP
0.10871 0.01988 0.10917 0.01127 0.04736 0.04791 0.00276 0.01078NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.06470 0.14451 0.14030 0.00000 0.00081 0.09673 0.00122 0.00312DER_IFN_ALPHA_RESPONSE_UP
0.00049 0.00018 0.00050 0.00000 0.00155 0.00000 0.00000 0.00001MCLACHLAN_DENTAL_CARIES_UP
0.00703 0.02309 0.00917 0.08533 0.02956 0.01391 0.11208 0.02293WU_HBX_TARGETS_1_UP
0.00017 0.00015 0.00000 0.00004 0.00133 0.00465 0.00028 0.13382PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.01506 0.00000 0.00807 0.00000 0.07447 0.02231 0.00291 0.00550CHEN_HOXA5_TARGETS_9HR_UP
0.11521 0.00079 0.01250 0.04745 0.03296 0.05324 0.00111 0.00228DAZARD_UV_RESPONSE_CLUSTER_G2
0.02712 0.00021 0.00711 0.00007 0.11144 0.05924 0.00000 0.00726NETPATH_IL_5_PATHWAY_UP
0.00078 0.00030 0.00065 0.00000 0.00444 0.00000 0.00000 0.00017MCLACHLAN_DENTAL_CARIES_DN
0.00381 0.17072 0.00563 0.02021 0.00724 0.00413 0.00000 0.16834LEE_LIVER_CANCER_E2F1_UP
0.00000 0.00006 0.00000 0.00001 0.00000 0.00078 0.00000 0.00037FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00002 0.00000 0.00001 0.00007 0.00000 0.00000 0.00002GAURNIER_PSMD4_TARGETS
0.00210 0.02029 0.00251 0.07324 0.02743 0.00000 0.00000 0.01964HELLER_SILENCED_BY_METHYLATION_UP
0.00810 0.00937 0.00398 0.00097 0.00000 0.00022 0.00003 0.00002GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.00059 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00025 0.01261 0.00061 0.00000 0.00006 0.00029 0.00000 0.06119ZHU_CMV_8_HR_UP
0.00491 0.03341 0.00471 0.00005 0.07695 0.00116 0.00000 0.05680MARKEY_RB1_CHRONIC_LOF_DN
0.00087 0.17326 0.00018 0.12803 0.13028 0.00253 0.00000 0.00710SMID_BREAST_CANCER_LUMINAL_B_DN
0.00000 0.00307 0.00000 0.00000 0.00000 0.03822 0.00012 0.00027ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00589 0.00000 0.00100 0.00000 0.00440 0.00020 0.01471NCI_IL23PATHWAY
0.00000 0.05381 0.00000 0.00012 0.00002 0.02390 0.00595 0.00030BIOCARTA_INFLAM_PATHWAY
0.00017 0.00000 0.00022 0.00000 0.00000 0.00008 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.02027 0.10038 0.02901 0.04900 0.00000 0.03237 0.00004 0.10440NCI_IL27PATHWAY
0.02769 0.02541 0.01129 0.00023 0.19319 0.03587 0.01080 0.00002SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.00000 0.00587 0.00004 0.00000 0.00000 0.00000 0.00000 0.09494FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.00013 0.00289 0.00007 0.00040 0.07807 0.00533 0.00009 0.02960AMIT_SERUM_RESPONSE_120_MCF10A
0.00065 0.03557 0.00022 0.00554 0.09938 0.03586 0.00036 0.00005ONDER_CDH1_TARGETS_2_DN
0.05191 0.06190 0.04794 0.00886 0.00356 0.08937 0.06247 0.07208NCI_IL1PATHWAY
0.00080 0.00215 0.00030 0.00000 0.02116 0.02652 0.00004 0.00011HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00757 0.00438 0.00078 0.00002 0.00136 0.11456 0.01412 0.02538SESTO_RESPONSE_TO_UV_C3
0.00075 0.01185 0.00019 0.12933 0.00313 0.09153 0.00974 0.06875SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2
0.00001 0.00063 0.00000 0.00000 0.02011 0.00000 0.00000 0.00218VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.01123 0.01130 0.04624 0.00001 0.02793 0.00011 0.00000 0.04896BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.00179 0.00000 0.00109 0.00027 0.00426 0.01274 0.00022 0.00007GEISS_RESPONSE_TO_DSRNA_UP
0.00145 0.03185 0.00200 0.00588 0.00006 0.05665 0.00252 0.01678KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.00514 0.11276 0.00272 0.00032 0.00145 0.00118 0.00030 0.03950GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.00000 0.00000 0.00000 0.00007 0.08234 0.10221 0.00336 0.02749UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00093 0.15849 0.00070 0.07166 0.14936 0.17607 0.00050 0.00499SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1
0.00277 0.00133 0.00040 0.00163 0.00008 0.05794 0.00116 0.00131GERY_CEBP_TARGETS
0.00709 0.05996 0.00272 0.04187 0.00033 0.00032 0.00000 0.06732NCI_IL12_2PATHWAY
0.00000 0.00000 0.00016 0.00054 0.00000 0.02222 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.02045 0.01293 0.03630 0.00000 0.03180 0.06440 0.00083 0.02420ZHU_CMV_ALL_UP
0.01769 0.02575 0.00994 0.00068 0.07512 0.01786 0.00006 0.00843NETPATH_IL_2_PATHWAY_UP
0.00027 0.01726 0.01680 0.02242 0.00000 0.00866 0.00000 0.09337KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00024 0.00000 0.00037 0.00001 0.00000 0.00033 0.00009 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00024 0.00000 0.00000 0.00000 0.00007 0.04640 0.00022 0.00000NETPATH_IL_1_PATHWAY_UP
0.00000 0.00010 0.00000 0.00001 0.01525 0.10357 0.00265 0.00011OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00139 0.07700 0.00058 0.02848 0.02142 0.02333 0.00011 0.00243LEE_LIVER_CANCER_HEPATOBLAST
0.08451 0.00723 0.04370 0.00518 0.03751 0.05374 0.00899 0.00002ZUCCHI_METASTASIS_DN
0.00000 0.00000 0.00000 0.00001 0.09324 0.01422 0.00000 0.00002NAGASHIMA_EGF_SIGNALING_UP
0.02502 0.00000 0.02844 0.01526 0.00000 0.12936 0.00099 0.00044PRAMOONJAGO_SOX4_TARGETS_UP
0.00000 0.00002 0.00000 0.00887 0.00605 0.01248 0.00107 0.06556PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.03435 0.00000 0.00034 0.00031 0.05376 0.00960 0.00151 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00000 0.00002 0.00000 0.01523 0.00467 0.06686 0.00070 0.00027AMIT_EGF_RESPONSE_60_MCF10A