BICLUSTER_ID : UPREG-458
PATHOGENS /3/ : brucella neotomae,mycobacterium tuberculosis,porphyromonas gingivalis
TARGETS /10/ : STAT1, PPARD, CCL8, CCL2, LPL, IL6, PTGS2, IL1B, CD86, PIM1
Gene SetLeading Edge Genes
NETPATH IL 3 PATHWAY UPIL1B, CCL2, CD86, PIM1
NETPATH IL 4 PATHWAY DOWNSTAT1, GADD45B, PTGS2, CCL2, LPL
NETPATH IL 6 PATHWAY UPSTAT1, GADD45B, PPARD, CEBPD, ZFP36, PIM1
NETPATH IL 4 PATHWAY UPGATA6, IL6, IBRDC3, CCL2, INHBA, CD86, EGR2
NCI IL23PATHWAYIL1B, CCL2
NETPATH IL 7 PATHWAY UPCCL8, CD86, CD19
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
ONDER CDH1 TARGETS 3 DN
ZHOU INFLAMMATORY RESPONSE LIVE UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
DAUER STAT3 TARGETS UP
NETPATH IL 9 PATHWAY UP
DAZARD RESPONSE TO UV NHEK UP
KEGG GRAFT VERSUS HOST DISEASE
MCLACHLAN DENTAL CARIES UP
GAJATE RESPONSE TO TRABECTEDIN UP
AMIT EGF RESPONSE 60 HELA
DAZARD UV RESPONSE CLUSTER G2
LINDSTEDT DENDRITIC CELL MATURATION B
MCLACHLAN DENTAL CARIES DN
TAVOR CEBPA TARGETS UP
HALMOS CEBPA TARGETS UP
LINDSTEDT DENDRITIC CELL MATURATION A
SEKI INFLAMMATORY RESPONSE LPS UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
AMIT EGF RESPONSE 40 HELA
SMID BREAST CANCER LUMINAL B DN
AMIT SERUM RESPONSE 120 MCF10A
NCI CHYLOMICRON MEDIATED LIPID TRANSPORT
MAHADEVAN RESPONSE TO MP470 DN
ZIRN TRETINOIN RESPONSE UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
HARRIS HYPOXIA
BROCKE APOPTOSIS REVERSED BY IL6
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION SUSTAINDED IN ERYTHROCYTE UP
GEISS RESPONSE TO DSRNA UP
HINATA NFKB TARGETS KERATINOCYTE UP
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
NAGASHIMA NRG1 SIGNALING UP
AMIT SERUM RESPONSE 60 MCF10A
SOUCEK MYC TARGETS
TIAN TNF SIGNALING VIA NFKB
DAVICIONI PAX FOXO1 SIGNATURE IN ARMS DN
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
BILBAN B CLL LPL DN
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
WATTEL AUTONOMOUS THYROID ADENOMA DN
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
porphyromonas gingivalismycobacterium tuberculosisbrucella neotomaeGeneSet Name
0.12641 0.00171 0.00000NETPATH_IL_3_PATHWAY_UP
0.00395 0.00000 0.00269NETPATH_IL_4_PATHWAY_DOWN
0.09273 0.00000 0.01660NETPATH_IL_6_PATHWAY_UP
0.03326 0.01106 0.10961NETPATH_IL_4_PATHWAY_UP
0.00584 0.00126 0.04130NCI_IL23PATHWAY
0.01741 0.00856 0.01290NETPATH_IL_7_PATHWAY_UP
0.00839 0.00225 0.17773KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.03623 0.00000 0.00128OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.00916 0.10086 0.01819ONDER_CDH1_TARGETS_3_DN
0.12784 0.00002 0.01309ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.02363 0.00002 0.03682GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00811 0.00000 0.00155DAUER_STAT3_TARGETS_UP
0.01126 0.08229 0.00066NETPATH_IL_9_PATHWAY_UP
0.10008 0.00196 0.11484DAZARD_RESPONSE_TO_UV_NHEK_UP
0.15597 0.02321 0.06507KEGG_GRAFT_VERSUS_HOST_DISEASE
0.08054 0.00000 0.00479MCLACHLAN_DENTAL_CARIES_UP
0.03047 0.00756 0.10625GAJATE_RESPONSE_TO_TRABECTEDIN_UP
0.11163 0.00000 0.04600AMIT_EGF_RESPONSE_60_HELA
0.01540 0.01541 0.00657DAZARD_UV_RESPONSE_CLUSTER_G2
0.02335 0.00000 0.02410LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.08235 0.00001 0.00595MCLACHLAN_DENTAL_CARIES_DN
0.02033 0.00011 0.11809TAVOR_CEBPA_TARGETS_UP
0.03979 0.01212 0.07569HALMOS_CEBPA_TARGETS_UP
0.00457 0.00000 0.00010LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00125 0.00000 0.00041SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00127 0.00000 0.00387ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00131 0.00000 0.01260AMIT_EGF_RESPONSE_40_HELA
0.04544 0.07952 0.18528SMID_BREAST_CANCER_LUMINAL_B_DN
0.00000 0.00013 0.11404AMIT_SERUM_RESPONSE_120_MCF10A
0.10415 0.15024 0.13065NCI_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT
0.01107 0.00000 0.00665MAHADEVAN_RESPONSE_TO_MP470_DN
0.04036 0.03003 0.07010ZIRN_TRETINOIN_RESPONSE_UP
0.05737 0.00000 0.00059HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00266 0.00000 0.04591SESTO_RESPONSE_TO_UV_C3
0.08079 0.00067 0.17495HARRIS_HYPOXIA
0.14398 0.00000 0.11642BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.07753 0.00199 0.16364TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP
0.12681 0.00000 0.01183GEISS_RESPONSE_TO_DSRNA_UP
0.00133 0.00000 0.09086HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.01492 0.00000 0.16491GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.00000 0.00000 0.00256UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00124 0.00000 0.06679NAGASHIMA_NRG1_SIGNALING_UP
0.00000 0.00001 0.11766AMIT_SERUM_RESPONSE_60_MCF10A
0.03916 0.02521 0.01093SOUCEK_MYC_TARGETS
0.00000 0.00000 0.05899TIAN_TNF_SIGNALING_VIA_NFKB
0.06592 0.00479 0.01946DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN
0.09753 0.00002 0.00010GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.09608 0.01866 0.03678BILBAN_B_CLL_LPL_DN
0.03617 0.00000 0.00123OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.11913 0.13990 0.17189LEE_LIVER_CANCER_HEPATOBLAST
0.00025 0.00000 0.01336NAGASHIMA_EGF_SIGNALING_UP
0.00483 0.00000 0.00214DIRMEIER_LMP1_RESPONSE_EARLY
0.18333 0.00004 0.09849MAHADEVAN_RESPONSE_TO_MP470_UP
0.00215 0.04327 0.08584WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN
0.10670 0.00000 0.16797PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.09026 0.00205 0.15401CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN
0.00000 0.00004 0.02489AMIT_EGF_RESPONSE_60_MCF10A