BICLUSTER_ID : UPREG-474
PATHOGENS /3/ : escherichia coli,fusobacterium nucleatum,shigella dysenteriae
TARGETS /3/ : PLAU, CD40LG, TNFRSF1B
Gene SetLeading Edge Genes
NETPATH TNF ALPHA PATHWAY UPOPTN, NFKBIE, MT1E, MYL2, TNFRSF1B, TMSB10, CREB5, PMAIP1, PLAU, NFKBIA, CD40LG, RIPK2, MT1H, MT3, PTX3, CXCL1, JUNB, PPP1R15A, BCL3, SILV, FGF3, ETS2, IFITM3, HIST1H2BO, IRF1, RAB13, DUSP1, IER2
NOJIMA SFRP2 TARGETS UP
NCI ATF2 PATHWAYSOCS3, ATF3, DUSP8, DUSP1
NCI FORMATION OF A POOL OF FREE 40S SUBUNITSRPS11, RPL38, RPS17, RPS3A, RPS6, RPS16, RPLP0, RPL22, RPS4X, RPS2, RPL39, RPL5, RPL37, RPL13A, RPS20, RPL41, RPS3, RPS27A, RPS15A, RPL35, RPS18, RPLP1, RPL23A, RPS10, RPS14, RPS5, RPS21, RPS23, RPL13, RPS19, RPL11, RPS12, RPL30, RPS7, RPL7A, RPL9, RPS13, RPS29, RPL8, RPL7, RPS24, RPS27, RPS15
CHO NR4A1 TARGETS
VANHARANTA UTERINE FIBROID DN
DAZARD RESPONSE TO UV NHEK UP
MARTINEZ RESPONSE TO TRABECTEDIN UP
REACTOME PEPTIDE CHAIN ELONGATION
SHAFFER IRF4 TARGETS IN PLASMA CELL VS MATURE B LYMPHOCYTE
CHEN LVAD SUPPORT OF FAILING HEART UP
DIRMEIER LMP1 RESPONSE LATE DN
KANNAN TP53 TARGETS UP
NCI VIRAL MRNA TRANSLATIONRPS11, RPL38, RPS17, RPS3A, RPS6, RPS16, RPLP0, RPL22, RPS4X, RPS2, RPL39, RPL5, RPL37, RPL13A, RPS20, RPL41, RPS3, RPS27A, RPS15A, RPL35, RPS18, RPLP1, RPL23A, RPS10, RPS14, RPS5, RPS21, RPS23, RPL13, RPS19, RPL11, RPS12, RPL30, RPS7, RPL7A, RPL9, RPS13, RPS29, RPL8, RPL7, RPS24, RPS27, RPS15
REACTOME VIRAL MRNA TRANSLATION
TONG INTERACT WITH PTTG1
AMIT SERUM RESPONSE 40 MCF10A
NCI GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS
DAZARD UV RESPONSE CLUSTER G24
NCI CAP DEPENDENT TRANSLATION INITIATION
NCI EUKARYOTIC TRANSLATION TERMINATIONRPS11, RPL38, RPS17, RPS3A, RPS6, RPS16, RPLP0, RPL22, RPS4X, RPS2, RPL39, RPL5, RPL37, RPL13A, RPS20, RPL41, RPS3, RPS27A, RPS15A, RPL35, RPS18, RPLP1, RPL23A, RPS10, RPS14, RPS5, RPS21, RPS23, RPL13, RPS19, RPL11, RPS12, RPL30, RPS7, RPL7A, RPL9, RPS13, RPS29, RPL8, RPL7, RPS24, RPS27, RPS15
NCI PEPTIDE CHAIN ELONGATIONRPS11, RPL38, RPS17, RPS3A, RPS6, RPS16, RPLP0, RPL22, EEF1A1, RPS4X, RPS2, RPL39, RPL5, RPL37, RPL13A, RPS20, RPL41, RPS3, RPS27A, RPS15A, RPL35, RPS18, RPLP1, RPL23A, RPS10, RPS14, RPS5, RPS21, RPS23, RPL13, RPS19, RPL11, RPS12, RPL30, RPL7A, RPS7, RPL9, RPS13, RPS29, RPL8, RPL7, RPS24, RPS27, RPS15
KIM LRRC3B TARGETS
AMIT EGF RESPONSE 40 HELA
GESERICK TERT TARGETS DN
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX
NCI FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEXRPS15A, RPS11, RPS18, RPS17, RPS3A, RPS10, RPS14, RPS16, RPS21, RPS23, RPS19, RPS12, RPS29, RPS13, RPS4X, RPS2, RPS27, RPS24, RPS20, RPS15, RPS27A, RPS3
MAHADEVAN RESPONSE TO MP470 DN
BROWNE HCMV INFECTION 2HR UP
KEGG RIBOSOME
KIM WT1 TARGETS UP
NCI RIBOSOMAL SCANNING AND START CODON RECOGNITION
ONDER CDH1 TARGETS 1 DN
CORUM 40S RIBOSOMAL SUBUNIT CYTOPLASMICRPS15A, RPS11, RPS18, RPS17, RPS3A, RPS10, RPS14, RPS16, RPS21, RPS23, RPS19, RPS12, RPS29, RPS13, RPS4X, RPS2, RPS27, RPS24, RPS20, RPS15, RPS27A, RPS3
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
REACTOME GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT
AMIT EGF RESPONSE 20 HELA
WEST ADRENOCORTICAL TUMOR DN
ENK UV RESPONSE KERATINOCYTE UP
DAZARD UV RESPONSE CLUSTER G3
REACTOME PACKAGING OF TELOMERE ENDS
REACTOME REGULATION OF BETA CELL DEVELOPMENT
TARTE PLASMA CELL VS PLASMABLAST UP
CHASSOT SKIN WOUND
REACTOME TRANSLATION INITIATION COMPLEX FORMATION
KEGG SYSTEMIC LUPUS ERYTHEMATOSUS
REACTOME FORMATION OF A POOL OF FREE 40S SUBUNITS
BILBAN B CLL LPL DN
DIRMEIER LMP1 RESPONSE EARLY
CORUM RIBOSOME CYTOPLASMICRPS11, RPL38, RPS17, RPS3A, RPS6, RPLP0, RPS16, RPL22, RPS4X, RPS2, RPL39, RPL5, RPL37, RPL13A, RPS20, RPS3, RPS27A, RPL41, RPL35, RPS15A, RPS18, RPL23A, RPLP1, RPS10, RPS14, RPS5, RPS21, RPL13, RPS23, RPS19, RPL11, RPS12, RPL30, RPS7, RPL7A, RPS29, RPS13, RPL9, RPL8, RPS27, RPS24, RPL7, RPS15
DAZARD UV RESPONSE CLUSTER G4
NCI L13A MEDIATED TRANSLATIONAL SILENCING OF CERULOPLASMIN EXPRESSION
HEDENFALK BREAST CANCER BRACX UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
fusobacterium nucleatumshigella dysenteriaeescherichia coliGeneSet Name
0.01710 0.07626 0.00001NETPATH_TNF_ALPHA_PATHWAY_UP
0.07293 0.00035 0.00018NOJIMA_SFRP2_TARGETS_UP
0.09472 0.00000 0.01874NCI_ATF2_PATHWAY
0.00000 0.00627 0.00702NCI_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS
0.04362 0.12162 0.14879CHO_NR4A1_TARGETS
0.19609 0.08927 0.00612VANHARANTA_UTERINE_FIBROID_DN
0.01697 0.00111 0.00002DAZARD_RESPONSE_TO_UV_NHEK_UP
0.01715 0.11706 0.02354MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP
0.00000 0.00324 0.00626REACTOME_PEPTIDE_CHAIN_ELONGATION
0.12433 0.03786 0.05575SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE
0.06956 0.00017 0.00159CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP
0.00017 0.06514 0.06500DIRMEIER_LMP1_RESPONSE_LATE_DN
0.06118 0.02322 0.02721KANNAN_TP53_TARGETS_UP
0.00000 0.00597 0.01461NCI_VIRAL_MRNA_TRANSLATION
0.00000 0.00478 0.01642REACTOME_VIRAL_MRNA_TRANSLATION
0.07260 0.18812 0.03590TONG_INTERACT_WITH_PTTG1
0.00145 0.00000 0.00142AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.00308 0.04260NCI_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT
0.00000 0.04000 0.05053REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS
0.09159 0.11525 0.17607DAZARD_UV_RESPONSE_CLUSTER_G24
0.00000 0.00337 0.06969NCI_CAP_DEPENDENT_TRANSLATION_INITIATION
0.00000 0.00438 0.01385NCI_EUKARYOTIC_TRANSLATION_TERMINATION
0.00000 0.00390 0.00472NCI_PEPTIDE_CHAIN_ELONGATION
0.15381 0.07873 0.00004KIM_LRRC3B_TARGETS
0.03469 0.00000 0.00000AMIT_EGF_RESPONSE_40_HELA
0.04180 0.00000 0.00083GESERICK_TERT_TARGETS_DN
0.18992 0.15816 0.01179GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.00000 0.07969 0.01227REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX
0.00000 0.07232 0.01008NCI_FORMATION_OF_THE_TERNARY_COMPLEX__AND_SUBSEQUENTLY__THE_43S_COMPLEX
0.01422 0.00000 0.00317MAHADEVAN_RESPONSE_TO_MP470_DN
0.08625 0.00008 0.00014BROWNE_HCMV_INFECTION_2HR_UP
0.00000 0.00526 0.11047KEGG_RIBOSOME
0.00000 0.00000 0.00002KIM_WT1_TARGETS_UP
0.00000 0.05452 0.13537NCI_RIBOSOMAL_SCANNING_AND_START_CODON_RECOGNITION
0.00000 0.09552 0.00021ONDER_CDH1_TARGETS_1_DN
0.00000 0.06290 0.00618CORUM_40S_RIBOSOMAL_SUBUNIT_CYTOPLASMIC
0.04380 0.00000 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00000 0.00284 0.05775REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT
0.00393 0.00013 0.00089AMIT_EGF_RESPONSE_20_HELA
0.15074 0.10600 0.12215WEST_ADRENOCORTICAL_TUMOR_DN
0.03493 0.01712 0.01710ENK_UV_RESPONSE_KERATINOCYTE_UP
0.18846 0.00253 0.00510DAZARD_UV_RESPONSE_CLUSTER_G3
0.11716 0.00000 0.16085REACTOME_PACKAGING_OF_TELOMERE_ENDS
0.00000 0.05170 0.12231REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT
0.09212 0.04650 0.03677TARTE_PLASMA_CELL_VS_PLASMABLAST_UP
0.00721 0.00141 0.17603CHASSOT_SKIN_WOUND
0.00000 0.05871 0.17917REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION
0.18810 0.00000 0.08323KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS
0.00000 0.00577 0.01101REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS
0.04894 0.00008 0.14289BILBAN_B_CLL_LPL_DN
0.01976 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00000 0.00348 0.00802CORUM_RIBOSOME_CYTOPLASMIC
0.02454 0.05435 0.16523DAZARD_UV_RESPONSE_CLUSTER_G4
0.00000 0.00439 0.08214NCI_L13A_MEDIATED_TRANSLATIONAL_SILENCING_OF_CERULOPLASMIN_EXPRESSION
0.01314 0.05570 0.03261HEDENFALK_BREAST_CANCER_BRACX_UP