BICLUSTER_ID : UPREG-476
PATHOGENS /3/ : pseudomonas aeruginosa,escherichia coli,helicobacter pylori
TARGETS /7/ : NFKB1, IL6, CCL20, PTGS2, ICAM1, CCL2, TLR2
Gene SetLeading Edge Genes
NETPATH IL 4 PATHWAY DOWNIL6, CCL20, PTGS2, ICAM1, NINJ1, IRF1, CXCL2, TLR2
NETPATH IL 1 PATHWAY UPBIRC3, CCL20, CXCL1, PLK2, CCL2, FOSL1, CXCL5, IL6, PTGS2, ICAM1, CXCL2, SOD2, PTX3
CORUM CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 COMPLEXNFKB1, REL, TNIP1, NFKB2, RELA
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
BIOCARTA STEM PATHWAY
DORN ADENOVIRUS INFECTION 32HR DN
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2
LINDSTEDT DENDRITIC CELL MATURATION B
CHEN HOXA5 TARGETS 9HR UP
DAZARD RESPONSE TO UV SCC UP
DAZARD UV RESPONSE CLUSTER G2
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
CHIARADONNA NEOPLASTIC TRANSFORMATION CDC25 UP
SEKI INFLAMMATORY RESPONSE LPS UP
GAURNIER PSMD4 TARGETS
REACTOME HUMAN TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX
SIMBULAN UV RESPONSE NORMAL UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
BIERIE INFLAMMATORY RESPONSE TGFB1
ONDER CDH1 SIGNALING VIA CTNNB1
ZHOU INFLAMMATORY RESPONSE LPS UP
BIOCARTA INFLAM PATHWAY
SANA TNF SIGNALING UP
SENESE HDAC1 AND HDAC2 TARGETS UP
DORN ADENOVIRUS INFECTION 12HR UP
SENESE HDAC1 TARGETS UP
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS CDC25 DN
FALVELLA SMOKERS WITH LUNG CANCER
SENESE HDAC3 TARGETS UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
ONDER CDH1 TARGETS 1 DN
HINATA NFKB TARGETS KERATINOCYTE UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX RPL6 RPL30 RPS13 CHUK DDX3X NFKB2 NFKBIB REL IKBKG NFKB1 MAP3K8 RELB GLG1 NFKBIA RELA TNIP2 GTF2I
MUELLER METHYLATED IN GLIOBLASTOMA
DORSAM HOXA9 TARGETS DN
BIOCARTA NTHI PATHWAY
SENESE HDAC2 TARGETS UP
AMIT EGF RESPONSE 120 MCF10A
TIAN TNF SIGNALING VIA NFKB
GILMORE CORE NFKB PATHWAY
CHIBA RESPONSE TO TSA DN
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
ZUCCHI METASTASIS DN
WU HBX TARGETS 2 DN
MAHADEVAN RESPONSE TO MP470 UP
HINATA NFKB TARGETS FIBROBLAST UP
FERRARI RESPONSE TO FENRETINIDE UP
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx1 mgeppseudomonas aeruginosa fdr1escherichia coliGeneSet Name
0.00002 0.04813 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.00000 0.10433 0.00000NETPATH_IL_1_PATHWAY_UP
0.01282 0.18914 0.00004CORUM_CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2_COMPLEX
0.10553 0.10974 0.00000CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.02218 0.13390 0.00000KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00095 0.03894 0.00000KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.03509 0.02861 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.02542 0.17983 0.00008BIOCARTA_STEM_PATHWAY
0.00013 0.15123 0.00003DORN_ADENOVIRUS_INFECTION_32HR_DN
0.00204 0.16271 0.00012CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_KPNA3_NFKB2_NFKBIB_REL_IKBKG__NFKB1_NFKBIE_RELB__NFKBIA_RELA_TNIP2
0.00000 0.05488 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00000 0.17362 0.00050CHEN_HOXA5_TARGETS_9HR_UP
0.10554 0.13027 0.14714DAZARD_RESPONSE_TO_UV_SCC_UP
0.00079 0.06185 0.00004DAZARD_UV_RESPONSE_CLUSTER_G2
0.00151 0.16409 0.10160GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.02804 0.14880 0.05333CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP
0.00000 0.03146 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00002 0.03111 0.00000GAURNIER_PSMD4_TARGETS
0.06009 0.17300 0.00016REACTOME_HUMAN_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX
0.02203 0.14633 0.01024SIMBULAN_UV_RESPONSE_NORMAL_UP
0.00937 0.01257 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00695 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00293 0.05278 0.00026IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00586 0.03714 0.01522BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.00188 0.14175 0.00015ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.00307 0.12972 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.05381 0.05657 0.00000BIOCARTA_INFLAM_PATHWAY
0.00000 0.17398 0.00000SANA_TNF_SIGNALING_UP
0.02541 0.05710 0.00002SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.00382 0.19224 0.04767DORN_ADENOVIRUS_INFECTION_12HR_UP
0.04120 0.02948 0.00079SENESE_HDAC1_TARGETS_UP
0.09986 0.05773 0.00220CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN
0.17053 0.05882 0.00399FALVELLA_SMOKERS_WITH_LUNG_CANCER
0.03411 0.09878 0.00076SENESE_HDAC3_TARGETS_UP
0.00015 0.13970 0.00002DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.03876 0.11008 0.00021ONDER_CDH1_TARGETS_1_DN
0.00002 0.02915 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00000 0.03344 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.03787 0.10861 0.00003CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_RPL6_RPL30_RPS13_CHUK_DDX3X_NFKB2_NFKBIB_REL_IKBKG_NFKB1_MAP3K8_RELB_GLG1_NFKBIA_RELA_TNIP2__GTF2I
0.17512 0.19020 0.19250MUELLER_METHYLATED_IN_GLIOBLASTOMA
0.06553 0.19026 0.11054DORSAM_HOXA9_TARGETS_DN
0.07883 0.05059 0.00024BIOCARTA_NTHI_PATHWAY
0.06019 0.14826 0.00293SENESE_HDAC2_TARGETS_UP
0.02386 0.06187 0.00004AMIT_EGF_RESPONSE_120_MCF10A
0.00000 0.01116 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.00003 0.19418 0.00003GILMORE_CORE_NFKB_PATHWAY
0.19719 0.07803 0.00034CHIBA_RESPONSE_TO_TSA_DN
0.00000 0.02819 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00723 0.03495 0.00000ZUCCHI_METASTASIS_DN
0.00624 0.19079 0.00219WU_HBX_TARGETS_2_DN
0.00002 0.03576 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.00000 0.00372 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00008 0.00812 0.00016FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00018 0.02841 0.00000REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES