BICLUSTER_ID : UPREG-54
PATHOGENS /3/ : mycobacterium tuberculosis,helicobacter pylori,shigella dysenteriae
TARGETS /18/ : CCL20, PDE4B, JUN, CCL2, TNFRSF1B, ALDOA, SAT1, NFKB1, GPRC5A, HMOX1, JAK2, CXCL12, IL6, PTGS2, ICAM1, IL1R1, PLAUR, TNF
Gene SetLeading Edge Genes
NETPATH IL 2 PATHWAY UPPFKFB3, PDE4B, JUN, TNFRSF1B, RGS16, NR4A2, FOSL2, BHLHB2, IER3, NFKB1, KLF6, CSF1, GADD45G, NFIL3, ICAM1, IL1R1, PLAUR, TNF
NETPATH IL 1 PATHWAY UPRHOB, CCL20, JUN, CCL2, NFKBIE, HBEGF, FOSL1, NFKBIA, INHBA, CXCL2, SOD2, NFKB1, BIRC3, CXCL1, JMJD3, PTGS2, ZFP36, ICAM1
NCI HIF1 TFPATHWAYPFKFB3, HK2, HMOX1, JUN, CXCL12, ADFP, HIF1A, ALDOA, ADM, BHLHB2
ST TUMOR NECROSIS FACTOR PATHWAYNFKB1, BIRC3, JUN, NFKB2, NFKBIE, TNFRSF1B, NFKBIA, TNFAIP3, TNF
NETPATH IL 5 PATHWAY UPPLSCR1, PDE4B, NFKB2, NFKBIE, CCL2, HBEGF, FOSL2, RELB, NFE2L2, IER3, MYD88, CASP4, NFKB1, BIRC3, REL, NFIL3, ICAM1, IER2
NCI TNFPATHWAYNFKB1, SQSTM1, TRAF1, BIRC3, TNFAIP3, CYLD, TNFRSF1B, TNF
NETPATH EGFR1 PATHWAY UPSNAI1, GPRC5A, PHLDA1, CDKN1A, EREG, HBEGF, PTGS2, TNFAIP3, SDC4, PLAUR, IER3
NCI IL6 7PATHWAYJAK2, CEBPD, JUN, JUNB, CEBPB, PRKCD, IL6, MAPK11, IRF1, PTPRE
NETPATH IL 4 PATHWAY UPNFKB1, MXD1, REL, JUN, CCL2, CEBPB, BCL3, ELL2, ARID5B, NFIL3, JAG1, INHBA, RIPK2, SLC11A2, PTX3
NCI IL1PATHWAYSQSTM1, NFKB1, JUN, IL1R1, MYD88
NETPATH TNF ALPHA PATHWAY DOWNCCL20, JUN, NFKBIA, FOSL2, CXCL2, BHLHB2, IER3, KLF6, CXCL1, JUNB, KLF10, TIPARP, MAFF, GEM, TNFAIP3, PTGS2, ZFP36
GERY CEBP TARGETSGADD45B, CXCL1, EREG, JUNB, DDIT3, HBEGF, GADD45G, RGS16, ATF3, SAT1, PLAUR, IER2, BTG2
NETPATH KIT RECEPTOR PATHWAY UPGDF15, JUNB, CCL2, TNF, IER3
NETPATH IL 6 PATHWAY UPGADD45B, CXCL1, CEBPD, JUN, JUNB, CEBPB, BCL3, MAP3K8, MAFF, ZFP36, BHLHB2, TNF
NCI CD40 PATHWAYTRAF1, NFKB1, NFKBIA, BIRC3, TNFAIP3, JUN
NETPATH IL 7 PATHWAY UPSLC3A2, CXCL1, JUN, LITAF, CXCL2
CORUM CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 COMPLEXNFKB1, NFKBIA, REL, NFKB2, NFKBIE
NETPATH IL 3 PATHWAY UPNFIL3, CSF1, CCL2
NCI NFKAPPABCANONICALPATHWAYNFKB1, NFKBIA, TNFAIP3, RIPK2, CYLD
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
NETPATH IL 9 PATHWAY UP
TURJANSKI MAPK7 TARGETS
BIOCARTA NFKB PATHWAY
MAHAJAN RESPONSE TO IL1A UP
BIOCARTA IL6 PATHWAY
VANHARANTA UTERINE FIBROID DN
CHUANG OXIDATIVE STRESS RESPONSE UP
BROWNE HCMV INFECTION 20HR UP
SHEPARD CRUSH AND BURN MUTANT UP
VARELA ZMPSTE24 TARGETS UP
LINDSTEDT DENDRITIC CELL MATURATION B
BIOCARTA IL1R PATHWAY
BIOCARTA RELA PATHWAY
RASHI RESPONSE TO IONIZING RADIATION 2
SESTO RESPONSE TO UV C0
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
MILI PSEUDOPODIA CHEMOTAXIS DN
KIM WT1 TARGETS 12HR DN
AMIT EGF RESPONSE 480 HELA
BROWNE HCMV INFECTION 10HR UP
JEON SMAD6 TARGETS UP
MITSIADES RESPONSE TO APLIDIN UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
LENAOUR DENDRITIC CELL MATURATION DN
MARTORIATI MDM4 TARGETS FETAL LIVER UP
HINATA NFKB TARGETS KERATINOCYTE UP
DORN ADENOVIRUS INFECTION 48HR DN
MARKEY RB1 ACUTE LOF UP
COULOUARN TEMPORAL TGFB1 SIGNATURE DN
AMIT SERUM RESPONSE 60 MCF10A
COULOUARN TEMPORAL TGFB1 SIGNATURE UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS MAGENTA UP
HUANG FOXA2 TARGETS UP
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
BIOCARTA CD40 PATHWAY
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP
AMIT EGF RESPONSE 120 HELA
BIOCARTA RANKL PATHWAY
DANG REGULATED BY MYC DN
MCLACHLAN DENTAL CARIES UP
GAJATE RESPONSE TO TRABECTEDIN UP
PODAR RESPONSE TO ADAPHOSTIN UP
SHAFFER IRF4 TARGETS IN PLASMA CELL VS MATURE B LYMPHOCYTE
KERLEY RESPONSE TO CISPLATIN UP
NCI IL23PATHWAY
ZHOU INFLAMMATORY RESPONSE LPS UP
NETPATH TGFBETA RECEPTOR PATHWAY DOWN
DORN ADENOVIRUS INFECTION 24HR DN
HALMOS CEBPA TARGETS DN
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
AMIT EGF RESPONSE 40 MCF10A
NCI P53DOWNSTREAMPATHWAY
BIOCARTA ATM PATHWAY
CHASSOT SKIN WOUND
TIAN TNF SIGNALING VIA NFKB
HUMMEL BURKITTS LYMPHOMA DN
KEGG APOPTOSIS
CORUM NFKB1-NFKB2-REL-RELA-RELB COMPLEX
HINATA NFKB TARGETS FIBROBLAST UP
ABRAHAM ALPC VS MULTIPLE MYELOMA UP
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN
MISSIAGLIA REGULATED BY METHYLATION UP
NCI ATF2 PATHWAY
GEORGANTAS HSC MARKERS
SESTO RESPONSE TO UV C1
CROONQUIST STROMAL STIMULATION UP
SA MMP CYTOKINE CONNECTION
DORN ADENOVIRUS INFECTION 48HR UP
ZHANG RESPONSE TO CANTHARIDIN UP
BLUM RESPONSE TO SALIRASIB UP
BOYLAN MULTIPLE MYELOMA C DN
NCI NFKAPPABALTERNATIVEPATHWAY
SIMBULAN UV RESPONSE NORMAL UP
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP
BIOCARTA CDMAC PATHWAY
HORIUCHI WTAP TARGETS UP
NETPATH IL 4 PATHWAY DOWN
DORN ADENOVIRUS INFECTION 12HR UP
RUTELLA RESPONSE TO CSF2RB AND IL4 DN
MORI PRE BI LYMPHOCYTE DN
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
NCI REGULATED PROTEOLYSIS OF P75NTR
AMIT EGF RESPONSE 20 HELA
BASSO CD40 SIGNALING UP
BIOCARTA NTHI PATHWAY
NAGASHIMA NRG1 SIGNALING UP
MARZEC IL2 SIGNALING UP
ENK UV RESPONSE EPIDERMIS DN
ZERBINI RESPONSE TO SULINDAC UP
FRIDMAN SENESCENCE UP
NETPATH B CELL RECEPTOR PATHWAY UP
MAHADEVAN RESPONSE TO MP470 UP
FERRARI RESPONSE TO FENRETINIDE UP
BIOCARTA TID PATHWAY
NCI P75NTR RECRUITS SIGNALLING COMPLEXES
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN DN
SIG CD40PATHWAYMAP
KEGG LEISHMANIA INFECTION
CHO NR4A1 TARGETS
NCI NF KB IS ACTIVATED AND SIGNALS SURVIVAL
SMITH TERT TARGETS UP
CHEN HOXA5 TARGETS 9HR UP
KANNAN TP53 TARGETS UP
SEKI INFLAMMATORY RESPONSE LPS UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
PARK TRETINOIN RESPONSE AND PML RARA FUSION
MURAKAMI UV RESPONSE 6HR UP
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP
WANG METHYLATED IN BREAST CANCER
SENESE HDAC1 TARGETS UP
REACTOME TOLL RECEPTOR CASCADES
INGA TP53 TARGETS
KIM WT1 TARGETS UP
REACTOME P75NTR SIGNALS VIA NFKB
ONDER CDH1 TARGETS 1 DN
BIOCARTA TNFR2 PATHWAY
NCI SMAD2 3NUCLEARPATHWAY
HESS TARGETS OF HOXA9 AND MEIS1 DN
ELVIDGE HYPOXIA BY DMOG UP
AMIT EGF RESPONSE 120 MCF10A
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
BERENJENO ROCK SIGNALING NOT VIA RHOA DN
RUTELLA RESPONSE TO HGF UP
PRAMOONJAGO SOX4 TARGETS UP
KIM WT1 TARGETS 8HR UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 1
LENAOUR DENDRITIC CELL MATURATION UP
CHEN LVAD SUPPORT OF FAILING HEART UP
TENEDINI MEGAKARYOCYTE MARKERS
LINDSTEDT DENDRITIC CELL MATURATION A
NETPATH IL 1 PATHWAY
ELVIDGE HYPOXIA UP
NETPATH T CELL RECEPTOR PATHWAY DOWN
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 5
TIEN INTESTINE PROBIOTICS 24HR DN
NUYTTEN NIPP1 TARGETS UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
DAZARD UV RESPONSE CLUSTER G3
XU HGF TARGETS INDUCED BY AKT1 48HR UP
OSADA ASCL1 TARGETS DN
GILMORE CORE NFKB PATHWAY
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
TSAI RESPONSE TO IONIZING RADIATION
DIRMEIER LMP1 RESPONSE EARLY
NCI NFAT TFPATHWAY
ZHOU INFLAMMATORY RESPONSE LIVE UP
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
DAZARD RESPONSE TO UV NHEK UP
WINTER HYPOXIA METAGENE
BROWNE HCMV INFECTION 8HR UP
NETPATH TNF ALPHA PATHWAY
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
FOSTER INFLAMMATORY RESPONSE LPS DN
TAVOR CEBPA TARGETS UP
GAURNIER PSMD4 TARGETS
OSAWA TNF TARGETS
NETPATH TNF ALPHA PATHWAY UP
GESERICK TERT TARGETS DN
NGUYEN NOTCH1 TARGETS DN
CLASPER LYMPHATIC VESSELS DURING METASTASIS UP
AMIT SERUM RESPONSE 120 MCF10A
BROWNE HCMV INFECTION 2HR UP
NCI VITAMIN D CALCIFEROL METABOLISM
BIOCARTA 41BB PATHWAY
SESTO RESPONSE TO UV C3
GEISS RESPONSE TO DSRNA UP
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX RPL6 RPL30 RPS13 CHUK DDX3X NFKB2 NFKBIB REL IKBKG NFKB1 MAP3K8 RELB GLG1 NFKBIA RELA TNIP2 GTF2I
GENTILE UV HIGH DOSE DN
BOYLAN MULTIPLE MYELOMA C CLUSTER DN
ZHOU INFLAMMATORY RESPONSE FIMA UP
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
AMIT DELAYED EARLY GENES
KRIGE AMINO ACID DEPRIVATION
GAZDA DIAMOND BLACKFAN ANEMIA MYELOID UP
AMIT EGF RESPONSE 60 MCF10A
NOJIMA SFRP2 TARGETS UP
CHEN HOXA5 TARGETS 6HR UP
NCI TCRCALCIUMPATHWAY
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
NETPATH EGFR1 PATHWAY DOWN
LEONARD HYPOXIA
NCI PDGFRAPATHWAY
RODRIGUES THYROID CARCINOMA DN
DORN ADENOVIRUS INFECTION 32HR DN
JIANG HYPOXIA NORMAL
HALMOS CEBPA TARGETS UP
CHIBA RESPONSE TO TSA
SAGIV CD24 TARGETS DN
SHAFFER IRF4 TARGETS IN MYELOMA VS MATURE B LYMPHOCYTE
KEGG MAPK SIGNALING PATHWAY
ONDER CDH1 SIGNALING VIA CTNNB1
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
ZHONG RESPONSE TO AZACITIDINE AND TSA UP
MAHADEVAN RESPONSE TO MP470 DN
DORN ADENOVIRUS INFECTION 12HR DN
HARRIS HYPOXIA
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP
CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA UP
KAN RESPONSE TO ARSENIC TRIOXIDE
ENK UV RESPONSE KERATINOCYTE UP
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES
SOUCEK MYC TARGETS
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
KEGG EPITHELIAL CELL SIGNALING IN HELICOBACTER PYLORI INFECTION
BILD HRAS ONCOGENIC SIGNATURE
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
MENSE HYPOXIA UPPTDSR, PFKFB3, CEBPD, CEBPB, TIPARP, NFIL3, ENO2, MAFF, ATF3, SOD2, BHLHB2
WANG ESOPHAGUS CANCER PROGRESSION UP
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN
AMIT EGF RESPONSE 60 HELA
BERENJENO TRANSFORMED BY RHOA FOREVER DN
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL
DAZARD UV RESPONSE CLUSTER G2
AMUNDSON DNA DAMAGE RESPONSE TP53
WANG CISPLATIN RESPONSE AND XPC DN
AMUNDSON RESPONSE TO ARSENITE
LEE SP4 THYMOCYTE
MCLACHLAN DENTAL CARIES DN
AMIT SERUM RESPONSE 40 MCF10A
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
BIOCARTA STRESS PATHWAY
HELLER SILENCED BY METHYLATION DN
SANA TNF SIGNALING UP
SENESE HDAC1 AND HDAC2 TARGETS UP
XU HGF TARGETS INDUCED BY AKT1 6HR
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
UDAYAKUMAR MED1 TARGETS DN
SENESE HDAC3 TARGETS UP
XU HGF SIGNALING NOT VIA AKT1 6HR
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
BIOCARTA KERATINOCYTE PATHWAY
KOBAYASHI EGFR SIGNALING 6HR DN
DASU IL6 SIGNALING UP
NETPATH T CELL RECEPTOR PATHWAY UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
ZUCCHI METASTASIS DN
BIOCARTA VIP PATHWAY
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx1 mgepmycobacterium tuberculosisshigella dysenteriaeGeneSet Name
0.02575 0.00008 0.08636NETPATH_IL_2_PATHWAY_UP
0.00000 0.00602 0.00030NETPATH_IL_1_PATHWAY_UP
0.00065 0.00318 0.08693NCI_HIF1_TFPATHWAY
0.00032 0.00010 0.01233ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00021 0.00000 0.00014NETPATH_IL_5_PATHWAY_UP
0.00024 0.01252 0.08513NCI_TNFPATHWAY
0.05959 0.01945 0.00148NETPATH_EGFR1_PATHWAY_UP
0.04616 0.00288 0.00624NCI_IL6_7PATHWAY
0.00423 0.01106 0.01729NETPATH_IL_4_PATHWAY_UP
0.06190 0.01300 0.02440NCI_IL1PATHWAY
0.00203 0.00002 0.00000NETPATH_TNF_ALPHA_PATHWAY_DOWN
0.00133 0.00000 0.00067GERY_CEBP_TARGETS
0.00065 0.00019 0.00112NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00236 0.00000 0.00000NETPATH_IL_6_PATHWAY_UP
0.00012 0.01575 0.00073NCI_CD40_PATHWAY
0.00294 0.00856 0.04120NETPATH_IL_7_PATHWAY_UP
0.01282 0.00431 0.07315CORUM_CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2_COMPLEX
0.03326 0.00171 0.00147NETPATH_IL_3_PATHWAY_UP
0.00742 0.00572 0.03623NCI_NFKAPPABCANONICALPATHWAY
0.03509 0.00002 0.00252GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00013 0.08229 0.05058NETPATH_IL_9_PATHWAY_UP
0.05499 0.18996 0.07009TURJANSKI_MAPK7_TARGETS
0.00155 0.00073 0.01398BIOCARTA_NFKB_PATHWAY
0.00517 0.00132 0.00316MAHAJAN_RESPONSE_TO_IL1A_UP
0.02454 0.06335 0.05423BIOCARTA_IL6_PATHWAY
0.00544 0.00382 0.08927VANHARANTA_UTERINE_FIBROID_DN
0.01119 0.02638 0.07731CHUANG_OXIDATIVE_STRESS_RESPONSE_UP
0.03937 0.04555 0.12944BROWNE_HCMV_INFECTION_20HR_UP
0.00460 0.00225 0.00030SHEPARD_CRUSH_AND_BURN_MUTANT_UP
0.00006 0.00035 0.00166VARELA_ZMPSTE24_TARGETS_UP
0.00000 0.00000 0.00053LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00078 0.00118 0.00825BIOCARTA_IL1R_PATHWAY
0.03110 0.03322 0.08410BIOCARTA_RELA_PATHWAY
0.00000 0.00000 0.00004RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.11121 0.00205 0.02792SESTO_RESPONSE_TO_UV_C0
0.00293 0.00217 0.00648IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00125 0.00000 0.00000AMIT_EGF_RESPONSE_40_HELA
0.17345 0.11221 0.14632MILI_PSEUDOPODIA_CHEMOTAXIS_DN
0.06995 0.11206 0.09521KIM_WT1_TARGETS_12HR_DN
0.01233 0.15992 0.03553AMIT_EGF_RESPONSE_480_HELA
0.06027 0.06597 0.10260BROWNE_HCMV_INFECTION_10HR_UP
0.00006 0.00136 0.02542JEON_SMAD6_TARGETS_UP
0.00011 0.00000 0.00008MITSIADES_RESPONSE_TO_APLIDIN_UP
0.00000 0.00000 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.11960 0.00000 0.02446LENAOUR_DENDRITIC_CELL_MATURATION_DN
0.03610 0.05130 0.02731MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP
0.00002 0.00000 0.00078HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00007 0.00008 0.00056DORN_ADENOVIRUS_INFECTION_48HR_DN
0.07713 0.00000 0.14227MARKEY_RB1_ACUTE_LOF_UP
0.16269 0.00340 0.09634COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN
0.00013 0.00001 0.00000AMIT_SERUM_RESPONSE_60_MCF10A
0.02584 0.02560 0.14473COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP
0.04809 0.00022 0.00000GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP
0.05378 0.10555 0.05174HUANG_FOXA2_TARGETS_UP
0.04004 0.00477 0.14554RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN
0.00018 0.00176 0.17156REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.02889 0.01971 0.00438BIOCARTA_CD40_PATHWAY
0.00007 0.00000 0.00009GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP
0.00003 0.00000 0.00113AMIT_EGF_RESPONSE_120_HELA
0.02627 0.03099 0.15704BIOCARTA_RANKL_PATHWAY
0.13597 0.00880 0.18421DANG_REGULATED_BY_MYC_DN
0.00018 0.00000 0.01598MCLACHLAN_DENTAL_CARIES_UP
0.09307 0.00756 0.10594GAJATE_RESPONSE_TO_TRABECTEDIN_UP
0.00015 0.00000 0.00000PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.17649 0.00911 0.03786SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE
0.02159 0.04549 0.16070KERLEY_RESPONSE_TO_CISPLATIN_UP
0.00589 0.00126 0.09953NCI_IL23PATHWAY
0.00307 0.00000 0.03754ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.14159 0.03994 0.11137NETPATH_TGFBETA_RECEPTOR_PATHWAY_DOWN
0.00013 0.00000 0.00042DORN_ADENOVIRUS_INFECTION_24HR_DN
0.08603 0.01693 0.00654HALMOS_CEBPA_TARGETS_DN
0.00063 0.00000 0.00095VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.01130 0.00000 0.00055BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.05254 0.00002 0.00000AMIT_EGF_RESPONSE_40_MCF10A
0.03315 0.08955 0.01375NCI_P53DOWNSTREAMPATHWAY
0.01028 0.13575 0.03423BIOCARTA_ATM_PATHWAY
0.01494 0.00066 0.00141CHASSOT_SKIN_WOUND
0.00000 0.00000 0.00005TIAN_TNF_SIGNALING_VIA_NFKB
0.02445 0.00035 0.03331HUMMEL_BURKITTS_LYMPHOMA_DN
0.16656 0.16900 0.06788KEGG_APOPTOSIS
0.00719 0.05523 0.19006CORUM_NFKB1-NFKB2-REL-RELA-RELB_COMPLEX
0.00000 0.00000 0.00153HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.03618 0.00975 0.06795ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP
0.10553 0.00002 0.18018CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.15874 0.00827 0.08446NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN
0.00725 0.00000 0.00484MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.02072 0.06127 0.00000NCI_ATF2_PATHWAY
0.16428 0.00021 0.05431GEORGANTAS_HSC_MARKERS
0.00084 0.01198 0.19068SESTO_RESPONSE_TO_UV_C1
0.03674 0.00025 0.00808CROONQUIST_STROMAL_STIMULATION_UP
0.01005 0.00814 0.10485SA_MMP_CYTOKINE_CONNECTION
0.12187 0.06332 0.05055DORN_ADENOVIRUS_INFECTION_48HR_UP
0.00152 0.00019 0.04574ZHANG_RESPONSE_TO_CANTHARIDIN_UP
0.00002 0.00143 0.02010BLUM_RESPONSE_TO_SALIRASIB_UP
0.01898 0.00171 0.02535BOYLAN_MULTIPLE_MYELOMA_C_DN
0.02162 0.00869 0.17714NCI_NFKAPPABALTERNATIVEPATHWAY
0.02203 0.04602 0.03162SIMBULAN_UV_RESPONSE_NORMAL_UP
0.12831 0.00065 0.17314KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP
0.07831 0.12581 0.00253BIOCARTA_CDMAC_PATHWAY
0.02539 0.00000 0.00236HORIUCHI_WTAP_TARGETS_UP
0.00002 0.00000 0.16501NETPATH_IL_4_PATHWAY_DOWN
0.00382 0.00008 0.00527DORN_ADENOVIRUS_INFECTION_12HR_UP
0.13491 0.00000 0.01423RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN
0.13814 0.00014 0.03794MORI_PRE_BI_LYMPHOCYTE_DN
0.00015 0.00000 0.00000DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.10723 0.17760 0.19044NCI_REGULATED_PROTEOLYSIS_OF_P75NTR
0.02197 0.00486 0.00013AMIT_EGF_RESPONSE_20_HELA
0.00077 0.00000 0.00004BASSO_CD40_SIGNALING_UP
0.07883 0.00063 0.00078BIOCARTA_NTHI_PATHWAY
0.00000 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.04862 0.00127 0.00321MARZEC_IL2_SIGNALING_UP
0.11657 0.00582 0.00875ENK_UV_RESPONSE_EPIDERMIS_DN
0.00318 0.04554 0.07968ZERBINI_RESPONSE_TO_SULINDAC_UP
0.19699 0.00067 0.08918FRIDMAN_SENESCENCE_UP
0.01192 0.00218 0.09708NETPATH_B_CELL_RECEPTOR_PATHWAY_UP
0.00002 0.00004 0.06328MAHADEVAN_RESPONSE_TO_MP470_UP
0.00008 0.00018 0.00712FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00325 0.01104 0.02606BIOCARTA_TID_PATHWAY
0.05390 0.04709 0.08515NCI_P75NTR_RECRUITS_SIGNALLING_COMPLEXES
0.05403 0.00534 0.06512ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN
0.07111 0.00798 0.17750SIG_CD40PATHWAYMAP
0.00031 0.00007 0.00317KEGG_LEISHMANIA_INFECTION
0.00941 0.00531 0.12162CHO_NR4A1_TARGETS
0.01074 0.03247 0.04605NCI_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL
0.00258 0.10092 0.04166SMITH_TERT_TARGETS_UP
0.00000 0.00006 0.00000CHEN_HOXA5_TARGETS_9HR_UP
0.00289 0.10269 0.02322KANNAN_TP53_TARGETS_UP
0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00937 0.00000 0.00003GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00002 0.00028 0.00146CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.03178 0.00026 0.08035PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION
0.19432 0.17085 0.12353MURAKAMI_UV_RESPONSE_6HR_UP
0.00000 0.00001 0.00000BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
0.01982 0.01939 0.10922WANG_METHYLATED_IN_BREAST_CANCER
0.04120 0.04425 0.02245SENESE_HDAC1_TARGETS_UP
0.08039 0.00015 0.15216REACTOME_TOLL_RECEPTOR_CASCADES
0.12773 0.12410 0.10402INGA_TP53_TARGETS
0.00000 0.00007 0.00000KIM_WT1_TARGETS_UP
0.00018 0.00334 0.01379REACTOME_P75NTR_SIGNALS_VIA_NFKB
0.03876 0.07350 0.09552ONDER_CDH1_TARGETS_1_DN
0.00067 0.00388 0.00110BIOCARTA_TNFR2_PATHWAY
0.05951 0.08808 0.09717NCI_SMAD2_3NUCLEARPATHWAY
0.04632 0.00000 0.00054HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.00023 0.00043 0.00078ELVIDGE_HYPOXIA_BY_DMOG_UP
0.02386 0.03451 0.02002AMIT_EGF_RESPONSE_120_MCF10A
0.00010 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.03851 0.00059 0.01384BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN
0.07973 0.00000 0.10389RUTELLA_RESPONSE_TO_HGF_UP
0.00000 0.00000 0.00000PRAMOONJAGO_SOX4_TARGETS_UP
0.00306 0.00125 0.00229KIM_WT1_TARGETS_8HR_UP
0.00002 0.00000 0.00000PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00221 0.03057 0.03633YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1
0.19240 0.00016 0.09817LENAOUR_DENDRITIC_CELL_MATURATION_UP
0.00038 0.00015 0.00017CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP
0.11465 0.13556 0.08527TENEDINI_MEGAKARYOCYTE_MARKERS
0.00015 0.00000 0.00034LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00053 0.03544 0.02164NETPATH_IL_1_PATHWAY
0.00083 0.00052 0.00124ELVIDGE_HYPOXIA_UP
0.15073 0.00067 0.18264NETPATH_T_CELL_RECEPTOR_PATHWAY_DOWN
0.00012 0.05325 0.02126YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5
0.10568 0.04549 0.06883TIEN_INTESTINE_PROBIOTICS_24HR_DN
0.14102 0.00000 0.09420NUYTTEN_NIPP1_TARGETS_UP
0.00005 0.00060 0.00096KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.06558 0.02412 0.00253DAZARD_UV_RESPONSE_CLUSTER_G3
0.03947 0.00027 0.03970XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP
0.10172 0.00021 0.01483OSADA_ASCL1_TARGETS_DN
0.00003 0.00092 0.02153GILMORE_CORE_NFKB_PATHWAY
0.01257 0.00000 0.08521NUYTTEN_EZH2_TARGETS_UP
0.00000 0.00002 0.02611DUTTA_APOPTOSIS_VIA_NFKB
0.00508 0.00008 0.00016TSAI_RESPONSE_TO_IONIZING_RADIATION
0.00157 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.11283 0.00205 0.00077NCI_NFAT_TFPATHWAY
0.00000 0.00002 0.00006ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.09618 0.00000 0.02436RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
0.01988 0.02002 0.13279NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.00624 0.00196 0.00111DAZARD_RESPONSE_TO_UV_NHEK_UP
0.00017 0.00019 0.04655WINTER_HYPOXIA_METAGENE
0.02400 0.00000 0.03443BROWNE_HCMV_INFECTION_8HR_UP
0.00091 0.07034 0.03020NETPATH_TNF_ALPHA_PATHWAY
0.00204 0.00136 0.04735CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_KPNA3_NFKB2_NFKBIB_REL_IKBKG__NFKB1_NFKBIE_RELB__NFKBIA_RELA_TNIP2
0.00151 0.00000 0.00000GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.00006 0.00000 0.00236FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.03788 0.00011 0.00349TAVOR_CEBPA_TARGETS_UP
0.00002 0.00000 0.04466GAURNIER_PSMD4_TARGETS
0.06007 0.07502 0.07902OSAWA_TNF_TARGETS
0.10562 0.00534 0.07626NETPATH_TNF_ALPHA_PATHWAY_UP
0.00257 0.00002 0.00000GESERICK_TERT_TARGETS_DN
0.00121 0.12700 0.02680NGUYEN_NOTCH1_TARGETS_DN
0.01277 0.05159 0.14239CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP
0.00289 0.00013 0.00021AMIT_SERUM_RESPONSE_120_MCF10A
0.00034 0.00000 0.00008BROWNE_HCMV_INFECTION_2HR_UP
0.05632 0.15021 0.02680NCI_VITAMIN_D__CALCIFEROL__METABOLISM
0.00912 0.03649 0.06816BIOCARTA_41BB_PATHWAY
0.00438 0.00000 0.00000SESTO_RESPONSE_TO_UV_C3
0.00000 0.00000 0.01687GEISS_RESPONSE_TO_DSRNA_UP
0.03787 0.00487 0.03385CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_RPL6_RPL30_RPS13_CHUK_DDX3X_NFKB2_NFKBIB_REL_IKBKG_NFKB1_MAP3K8_RELB_GLG1_NFKBIA_RELA_TNIP2__GTF2I
0.00807 0.13562 0.00820GENTILE_UV_HIGH_DOSE_DN
0.07759 0.04451 0.07953BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN
0.00157 0.00047 0.01029ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.07700 0.13990 0.00154LEE_LIVER_CANCER_HEPATOBLAST
0.00000 0.00000 0.00000NAGASHIMA_EGF_SIGNALING_UP
0.00013 0.00001 0.00000AMIT_DELAYED_EARLY_GENES
0.00000 0.00064 0.03473KRIGE_AMINO_ACID_DEPRIVATION
0.14165 0.06258 0.07630GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_UP
0.00002 0.00004 0.00000AMIT_EGF_RESPONSE_60_MCF10A
0.00032 0.00000 0.00035NOJIMA_SFRP2_TARGETS_UP
0.00126 0.00079 0.00221CHEN_HOXA5_TARGETS_6HR_UP
0.17276 0.04081 0.03669NCI_TCRCALCIUMPATHWAY
0.00008 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.07692 0.00000 0.05182SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.09276 0.00000 0.06296NETPATH_EGFR1_PATHWAY_DOWN
0.00002 0.01105 0.01701LEONARD_HYPOXIA
0.14785 0.17622 0.11428NCI_PDGFRAPATHWAY
0.00156 0.01698 0.15261RODRIGUES_THYROID_CARCINOMA_DN
0.00013 0.00008 0.00014DORN_ADENOVIRUS_INFECTION_32HR_DN
0.04984 0.00018 0.14726JIANG_HYPOXIA_NORMAL
0.01235 0.01212 0.00005HALMOS_CEBPA_TARGETS_UP
0.04619 0.00009 0.01239CHIBA_RESPONSE_TO_TSA
0.03235 0.00000 0.01026SAGIV_CD24_TARGETS_DN
0.11777 0.05116 0.14059SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE
0.18732 0.08402 0.01671KEGG_MAPK_SIGNALING_PATHWAY
0.00188 0.01211 0.01233ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.08369 0.01382 0.15816GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.06179 0.01736 0.05696ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP
0.00340 0.00000 0.00000MAHADEVAN_RESPONSE_TO_MP470_DN
0.00586 0.00753 0.00032DORN_ADENOVIRUS_INFECTION_12HR_DN
0.00027 0.00067 0.00501HARRIS_HYPOXIA
0.04563 0.00022 0.11015KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP
0.00104 0.00577 0.00304CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP
0.01515 0.00571 0.02489KAN_RESPONSE_TO_ARSENIC_TRIOXIDE
0.00938 0.00959 0.01712ENK_UV_RESPONSE_KERATINOCYTE_UP
0.02639 0.02725 0.07100REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES
0.00011 0.02521 0.02047SOUCEK_MYC_TARGETS
0.00543 0.00228 0.11301TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.00103 0.00130 0.11725KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION
0.00029 0.00000 0.00000BILD_HRAS_ONCOGENIC_SIGNATURE
0.00067 0.00000 0.00005DAUER_STAT3_TARGETS_UP
0.00031 0.00000 0.00396LIANG_SILENCED_BY_METHYLATION_2
0.00855 0.00000 0.02114MENSE_HYPOXIA_UP
0.08290 0.00139 0.02346WANG_ESOPHAGUS_CANCER_PROGRESSION_UP
0.00015 0.00008 0.00827ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN
0.00002 0.00000 0.00007AMIT_EGF_RESPONSE_60_HELA
0.08229 0.08977 0.00170BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.00516 0.02942 0.05323REACTOME_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL
0.00079 0.01541 0.00032DAZARD_UV_RESPONSE_CLUSTER_G2
0.09365 0.02253 0.00538AMUNDSON_DNA_DAMAGE_RESPONSE_TP53
0.09555 0.13930 0.13229WANG_CISPLATIN_RESPONSE_AND_XPC_DN
0.00012 0.03519 0.17228AMUNDSON_RESPONSE_TO_ARSENITE
0.09234 0.00049 0.03500LEE_SP4_THYMOCYTE
0.00030 0.00001 0.02949MCLACHLAN_DENTAL_CARIES_DN
0.00874 0.00000 0.00000AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.01749 0.06124 0.00630BIOCARTA_STRESS_PATHWAY
0.00014 0.00045 0.07958HELLER_SILENCED_BY_METHYLATION_DN
0.00000 0.00000 0.00530SANA_TNF_SIGNALING_UP
0.02541 0.01303 0.00255SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.04723 0.00001 0.07814XU_HGF_TARGETS_INDUCED_BY_AKT1_6HR
0.00215 0.00000 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00018 0.00070 0.01643UDAYAKUMAR_MED1_TARGETS_DN
0.03411 0.00552 0.02950SENESE_HDAC3_TARGETS_UP
0.00018 0.00239 0.00031XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR
0.00000 0.00000 0.00000UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00546 0.13412 0.00147BIOCARTA_KERATINOCYTE_PATHWAY
0.00064 0.00020 0.00127KOBAYASHI_EGFR_SIGNALING_6HR_DN
0.07974 0.00006 0.00099DASU_IL6_SIGNALING_UP
0.09515 0.12091 0.15288NETPATH_T_CELL_RECEPTOR_PATHWAY_UP
0.00000 0.00002 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00723 0.00039 0.00013ZUCCHI_METASTASIS_DN
0.10236 0.11170 0.06266BIOCARTA_VIP_PATHWAY