BICLUSTER_ID : UPREG-64
PATHOGENS /3/ : pseudomonas aeruginosa,yersinia enterocolitica,ehrlichia chaffeensis
TARGETS /11/ : IL2RB, JAK2, CCL2, TNFRSF1B, SERPINB2, IL6, IL1B, PTGS2, CASP1, IL1R1, PLAUR
Gene SetLeading Edge Genes
NETPATH IL 2 PATHWAY UPGBP1, TNFRSF1B, NMI, TRAFD1, PMAIP1, IFI44, IER3, IFIT1, KLF6, SP100, IL2RB, CSF1, PTPRC, TRIM21, TNFRSF11A, SRC, FAS, IL6, IL1B, DAXX, CASP1, IRF1, PLAUR
NCI IL23PATHWAYIL6, IL1B, JAK2, CXCL1, CCL2
NCI IL12 2PATHWAYIL2RB, GADD45B, IL1B, JAK2, NFKB2, IL1R1
NETPATH IL 1 PATHWAY UPCXCL5, IL6, PTGS2, CXCL1, CXCL2, SERPINB2, IL1A
NETPATH IL 4 PATHWAY DOWNIL6, GADD45B, PTGS2, CCL2, IRF1, CXCL2
NCI AMB2 NEUTROPHILS PATHWAYSRC, IL6, PLAUR, LAMC3
GERY CEBP TARGETSGADD45B, CXCL1, EREG, JUNB, KLF4, SERPINB2, CXCL5, ATF3, IFRD1, MAFK, PLAUR
ST STAT3 PATHWAYSRC, IL6, JAK2
NETPATH IL 9 PATHWAY UPCCL2, JUNB
NETPATH IL 5 PATHWAY UPNFKBIB, PLSCR1, REL, NFKB2, CCL2, IL1A, IER3, EGR2
BIOCARTA IL10 PATHWAY
BIOCARTA PML PATHWAY
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
BIOCARTA NFKB PATHWAY
MAHAJAN RESPONSE TO IL1A UP
WEINMANN ADAPTATION TO HYPOXIA DN
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS
VARELA ZMPSTE24 TARGETS UP
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
REACTOME PEPTIDE LIGAND BINDING RECEPTORS
TENEDINI MEGAKARYOCYTE MARKERS
LINDSTEDT DENDRITIC CELL MATURATION B
BIOCARTA IL1R PATHWAY
MCBRYAN PUBERTAL BREAST 4 5WK UP
KRASNOSELSKAYA ILF3 TARGETS UP
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL UP
XU RESPONSE TO TRETINOIN UP
ELVIDGE HYPOXIA UP
AMIT EGF RESPONSE 40 HELA
NETPATH TGFBETA RECEPTOR PATHWAY UP
BOWIE RESPONSE TO EXTRACELLULAR MATRIX
NETPATH IL 7 PATHWAY UPCXCL5, FAS, CXCL1, CXCL2
BIOCARTA NKT PATHWAY
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 5
JEON SMAD6 TARGETS UP
MITSIADES RESPONSE TO APLIDIN UP
BROWNE INTERFERON RESPONSIVE GENES
NCI IL6 7PATHWAY
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
ROETH TERT TARGETS UP
BIOCARTA LAIR PATHWAY
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION SUSTAINDED IN ERYTHROCYTE UP
BOYAULT LIVER CANCER SUBCLASS G56 DN
HINATA NFKB TARGETS KERATINOCYTE UP
KOKKINAKIS METHIONINE DEPRIVATION 96HR UP
MARKEY RB1 ACUTE LOF UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
DAZARD UV RESPONSE CLUSTER G3
XU HGF TARGETS INDUCED BY AKT1 48HR UP
OSADA ASCL1 TARGETS DN
VART KSHV INFECTION ANGIOGENIC MARKERS UP
REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS
BIOCARTA LYM PATHWAY
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
BIOCARTA IL22BP PATHWAY
HUANG FOXA2 TARGETS UP
DELYS THYROID CANCER UP
TSAI RESPONSE TO IONIZING RADIATION
DIRMEIER LMP1 RESPONSE EARLY
DER IFN GAMMA RESPONSE UP
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN
AMIT SERUM RESPONSE 240 MCF10A
KEGG INTESTINAL IMMUNE NETWORK FOR IGA PRODUCTION
MCMURRAY TP53 HRAS COOPERATION RESPONSE UP
LIU VAV3 PROSTATE CARCINOGENESIS UP
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION UP
BENNETT SYSTEMIC LUPUS ERYTHEMATOSUS
NCI NFAT TFPATHWAY
ONDER CDH1 TARGETS 3 DN
ZHOU INFLAMMATORY RESPONSE LIVE UP
AMIT EGF RESPONSE 120 HELA
HELLEBREKERS SILENCED DURING TUMOR ANGIOGENESIS
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
NCI CHEMOKINE RECEPTORS BIND CHEMOKINES
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
MCLACHLAN DENTAL CARIES UP
WINTER HYPOXIA METAGENE
NEWMAN ERCC6 TARGETS UP
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2
PODAR RESPONSE TO ADAPHOSTIN UP
FOSTER INFLAMMATORY RESPONSE LPS DN
LEE LIVER CANCER E2F1 UP
TAVOR CEBPA TARGETS UP
GAURNIER PSMD4 TARGETS
HELLER SILENCED BY METHYLATION UP
GRANDVAUX IFN RESPONSE NOT VIA IRF3
KEGG CELL ADHESION MOLECULES CAMS
BOWIE RESPONSE TO TAMOXIFEN
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
NETPATH TNF ALPHA PATHWAY UP
MARKEY RB1 CHRONIC LOF DN
SMID BREAST CANCER LUMINAL B DN
ZHOU INFLAMMATORY RESPONSE LPS UP
NOJIMA SFRP2 TARGETS DN
NETPATH TGFBETA RECEPTOR PATHWAY DOWN
AMIT SERUM RESPONSE 120 MCF10A
FURUKAWA DUSP6 TARGETS PCI35 UP
BROWNE HCMV INFECTION 2HR UP
VANTVEER BREAST CANCER ESR1 DN
CORUM REL-MAP3K8-RELA-TNIP2-PAPOLA COMPLEX
LEE LIVER CANCER MYC E2F1 UP
SESTO RESPONSE TO UV C3
BIOCARTA IL17 PATHWAY
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
REACTOME DEATH RECEPTOR SIGNALLING
GEISS RESPONSE TO DSRNA UP
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
NCI P53DOWNSTREAMPATHWAY
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1
CORUM IKBEPSILON-RELA-CREL COMPLEX
ST TUMOR NECROSIS FACTOR PATHWAY
ZHOU INFLAMMATORY RESPONSE FIMA UP
TIAN TNF SIGNALING VIA NFKB
GRUETZMANN PANCREATIC CANCER UP
ROZANOV MMP14 TARGETS UP
ZHU CMV ALL UP
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
OKUMURA INFLAMMATORY RESPONSE LPS
KEGG APOPTOSIS
NATSUME RESPONSE TO INTERFERON BETA UP
CORUM NFKB1-NFKB2-REL-RELA-RELB COMPLEX
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
AMIT DELAYED EARLY GENES
KEGG TYPE I DIABETES MELLITUS
HUANG DASATINIB RESISTANCE UP
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN
AMIT EGF RESPONSE 60 MCF10A
HINATA NFKB TARGETS FIBROBLAST UP
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
MISSIAGLIA REGULATED BY METHYLATION UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
LEONARD HYPOXIA
REACTOME SIGNAL AMPLIFICATION
CHEN LVAD SUPPORT OF FAILING HEART DN
ZHANG INTERFERON RESPONSE
SESTO RESPONSE TO UV C1
LEE LIVER CANCER MYC TGFA UP
CROONQUIST STROMAL STIMULATION UP
HALMOS CEBPA TARGETS UP
WU CELL MIGRATION
WALLACE PROSTATE CANCER RACE UP
SAGIV CD24 TARGETS DN
KEGG ECM RECEPTOR INTERACTION
KIM LRRC3B TARGETS
HORIUCHI WTAP TARGETS UP
WIELAND UP BY HBV INFECTION
ONDER CDH1 SIGNALING VIA CTNNB1
WOO LIVER CANCER RECURRENCE UP
ZHONG RESPONSE TO AZACITIDINE AND TSA UP
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN UP
MAHADEVAN RESPONSE TO MP470 DN
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS CDC25 DN
UROSEVIC RESPONSE TO IMIQUIMOD
KEGG JAK STAT SIGNALING PATHWAY
HARRIS HYPOXIA
NETPATH KIT RECEPTOR PATHWAY UP
DER IFN BETA RESPONSE UP
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
BIOCARTA CYTOKINE PATHWAY
SEIKE LUNG CANCER POOR SURVIVAL
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D DN
BASSO CD40 SIGNALING UP
MUELLER METHYLATED IN GLIOBLASTOMA
NCI IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL
MARZEC IL2 SIGNALING UP
NAGASHIMA NRG1 SIGNALING UP
SOUCEK MYC TARGETS
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
ZERBINI RESPONSE TO SULINDAC UP
SCIAN INVERSED TARGETS OF TP53 AND TP73 DN
WANG ESOPHAGUS CANCER VS NORMAL UP
FRIDMAN SENESCENCE UP
CROMER TUMORIGENESIS UP
NCI PTP1BPATHWAY
IZADPANAH STEM CELL ADIPOSE VS BONE UP
WU HBX TARGETS 2 DN
NETPATH B CELL RECEPTOR PATHWAY UP
MAHADEVAN RESPONSE TO MP470 UP
CORUM ITGA2B-ITGB3-CD47-SRC COMPLEX
ZHAN MULTIPLE MYELOMA LB DN
FERRARI RESPONSE TO FENRETINIDE UP
BIOCARTA TID PATHWAY
SHAFFER IRF4 MULTIPLE MYELOMA PROGRAM
BILD HRAS ONCOGENIC SIGNATURE
SANA RESPONSE TO IFNG UP
LIANG SILENCED BY METHYLATION 2
DAUER STAT3 TARGETS UP
NETPATH IL 3 PATHWAY UP
KEGG LEISHMANIA INFECTION
NETPATH IL 6 PATHWAY UPMAFF, GADD45B, CXCL1, JUNB, IRF1, MAP3K8
DER IFN ALPHA RESPONSE UP
WANG ESOPHAGUS CANCER PROGRESSION UP
WU HBX TARGETS 1 UP
BERENJENO TRANSFORMED BY RHOA FOREVER DN
CHEN HOXA5 TARGETS 9HR UP
DAZARD UV RESPONSE CLUSTER G2
EINAV INTERFERON SIGNATURE IN CANCER
MCLACHLAN DENTAL CARIES DN
KEGG ALLOGRAFT REJECTION
SEKI INFLAMMATORY RESPONSE LPS UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
ZHU CMV 8 HR UP
BIERIE INFLAMMATORY RESPONSE TGFB1
BIOCARTA INFLAM PATHWAY
SANA TNF SIGNALING UP
MOSERLE IFNA RESPONSE
NCI IL27PATHWAY
SENESE HDAC1 AND HDAC2 TARGETS UP
FOSTER INFLAMMATORY RESPONSE LPS UP
BIOCARTA ASBCELL PATHWAY
ONDER CDH1 TARGETS 2 DN
SENESE HDAC1 TARGETS UP
LIU TARGETS OF VMYB VS CMYB DN
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
ODONNELL TARGETS OF MYC AND TFRC UP
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 2
VICENT METASTASIS DN
KIM WT1 TARGETS UP
SENESE HDAC3 TARGETS UP
KEGG CHEMOKINE SIGNALING PATHWAY
FUJII YBX1 TARGETS UP
CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL DN
KEGG CYTOSOLIC DNA SENSING PATHWAY
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
XU HGF SIGNALING NOT VIA AKT1 6HR
BIOCARTA KERATINOCYTE PATHWAY
JISON SICKLE CELL DISEASE UP
BIOCARTA GRANULOCYTES PATHWAY
LINDSTEDT DENDRITIC CELL MATURATION C
XU HGF SIGNALING NOT VIA AKT1 48HR UP
DASU IL6 SIGNALING UP
ELVIDGE HYPOXIA BY DMOG UP
HUPER BREAST BASAL VS LUMINAL UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
NCI PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
ZUCCHI METASTASIS DN
SMID BREAST CANCER RELAPSE IN BONE DN
SMID BREAST CANCER BASAL UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
YAMASHITA METHYLATED IN PROSTATE CANCER
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
ehrlichia chaffeensis arkansayersinia enterocolitica p60 bcpseudomonas aeruginosa fdr440GeneSet Name
0.00029 0.00018 0.00843NETPATH_IL_2_PATHWAY_UP
0.00000 0.00000 0.01471NCI_IL23PATHWAY
0.00000 0.00140 0.06732NCI_IL12_2PATHWAY
0.00744 0.00001 0.00000NETPATH_IL_1_PATHWAY_UP
0.00001 0.00040 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.00021 0.00186 0.00315NCI_AMB2_NEUTROPHILS_PATHWAY
0.01308 0.00510 0.00131GERY_CEBP_TARGETS
0.00333 0.05260 0.07697ST_STAT3_PATHWAY
0.00097 0.00009 0.04269NETPATH_IL_9_PATHWAY_UP
0.00007 0.00159 0.00726NETPATH_IL_5_PATHWAY_UP
0.00082 0.00003 0.01645BIOCARTA_IL10_PATHWAY
0.01308 0.02683 0.00518BIOCARTA_PML_PATHWAY
0.00021 0.00000 0.01700GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.06659 0.03120 0.00100BIOCARTA_NFKB_PATHWAY
0.01198 0.00009 0.00044MAHAJAN_RESPONSE_TO_IL1A_UP
0.01089 0.00000 0.01567WEINMANN_ADAPTATION_TO_HYPOXIA_DN
0.00034 0.00417 0.17577REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS
0.05834 0.15192 0.05018VARELA_ZMPSTE24_TARGETS_UP
0.00000 0.00000 0.00068ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.00094 0.00005 0.02145REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
0.00000 0.02423 0.05310TENEDINI_MEGAKARYOCYTE_MARKERS
0.00007 0.00237 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.17481 0.00008 0.06380BIOCARTA_IL1R_PATHWAY
0.01143 0.01369 0.11152MCBRYAN_PUBERTAL_BREAST_4_5WK_UP
0.00016 0.00020 0.11846KRASNOSELSKAYA_ILF3_TARGETS_UP
0.00307 0.00008 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00000 0.00000 0.00003LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.03933 0.00171 0.00347LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP
0.03915 0.07466 0.10393XU_RESPONSE_TO_TRETINOIN_UP
0.01170 0.00036 0.16459ELVIDGE_HYPOXIA_UP
0.03874 0.00031 0.15015AMIT_EGF_RESPONSE_40_HELA
0.18277 0.08744 0.00516NETPATH_TGFBETA_RECEPTOR_PATHWAY_UP
0.00254 0.00683 0.03539BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX
0.00034 0.00028 0.00003NETPATH_IL_7_PATHWAY_UP
0.00005 0.03708 0.01701BIOCARTA_NKT_PATHWAY
0.00697 0.14881 0.06558YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5
0.00046 0.03022 0.00005JEON_SMAD6_TARGETS_UP
0.09988 0.10630 0.01817MITSIADES_RESPONSE_TO_APLIDIN_UP
0.00000 0.00000 0.00002BROWNE_INTERFERON_RESPONSIVE_GENES
0.00000 0.07282 0.14730NCI_IL6_7PATHWAY
0.01384 0.00000 0.00052THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00081 0.00004 0.11741TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.01826 0.00741 0.10447ROETH_TERT_TARGETS_UP
0.00046 0.00240 0.01830BIOCARTA_LAIR_PATHWAY
0.04656 0.00729 0.06129TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP
0.00017 0.14873 0.00799BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN
0.00055 0.00000 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.03945 0.11062 0.05096KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP
0.00000 0.00004 0.01820MARKEY_RB1_ACUTE_LOF_UP
0.00013 0.00008 0.00034KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.03910 0.19949 0.01564DAZARD_UV_RESPONSE_CLUSTER_G3
0.12062 0.02457 0.00999XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP
0.00001 0.06140 0.11392OSADA_ASCL1_TARGETS_DN
0.02454 0.00016 0.08419VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP
0.00904 0.14447 0.14742REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS
0.00036 0.04751 0.01705BIOCARTA_LYM_PATHWAY
0.00475 0.00032 0.00021NUYTTEN_EZH2_TARGETS_UP
0.00000 0.00013 0.00513DUTTA_APOPTOSIS_VIA_NFKB
0.01255 0.06295 0.08742BIOCARTA_IL22BP_PATHWAY
0.16421 0.08583 0.17959HUANG_FOXA2_TARGETS_UP
0.00020 0.08331 0.00736DELYS_THYROID_CANCER_UP
0.00169 0.19909 0.04793TSAI_RESPONSE_TO_IONIZING_RADIATION
0.00000 0.00000 0.00002DIRMEIER_LMP1_RESPONSE_EARLY
0.00007 0.00263 0.00011DER_IFN_GAMMA_RESPONSE_UP
0.01711 0.03733 0.00883RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN
0.12099 0.02551 0.00002AMIT_SERUM_RESPONSE_240_MCF10A
0.00899 0.13189 0.03514KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION
0.00024 0.00725 0.10700MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_UP
0.00000 0.08100 0.00848LIU_VAV3_PROSTATE_CARCINOGENESIS_UP
0.00000 0.00000 0.00009REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.00001 0.00000 0.05479SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP
0.00000 0.00003 0.06522BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS
0.03630 0.09530 0.04224NCI_NFAT_TFPATHWAY
0.02809 0.00099 0.00194ONDER_CDH1_TARGETS_3_DN
0.01092 0.00000 0.00010ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.07404 0.00004 0.00068AMIT_EGF_RESPONSE_120_HELA
0.13021 0.00048 0.00016HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS
0.00000 0.08621 0.05763NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.06101 0.06147 0.03208NCI_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.00549 0.06188 0.01555FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP
0.01021 0.00659 0.01078NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.00000 0.00008 0.00001MCLACHLAN_DENTAL_CARIES_UP
0.11984 0.00442 0.00135WINTER_HYPOXIA_METAGENE
0.00936 0.03715 0.03524NEWMAN_ERCC6_TARGETS_UP
0.13511 0.02325 0.00016CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_KPNA3_NFKB2_NFKBIB_REL_IKBKG__NFKB1_NFKBIE_RELB__NFKBIA_RELA_TNIP2
0.00428 0.00001 0.13382PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.00000 0.00000 0.00037FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.00219 0.16834LEE_LIVER_CANCER_E2F1_UP
0.00572 0.02930 0.08516TAVOR_CEBPA_TARGETS_UP
0.00000 0.00000 0.00002GAURNIER_PSMD4_TARGETS
0.00000 0.00028 0.01964HELLER_SILENCED_BY_METHYLATION_UP
0.00010 0.00097 0.04085GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3
0.03115 0.11863 0.06288KEGG_CELL_ADHESION_MOLECULES_CAMS
0.00015 0.00077 0.04904BOWIE_RESPONSE_TO_TAMOXIFEN
0.02810 0.11465 0.01084SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.04059 0.14780 0.00318NETPATH_TNF_ALPHA_PATHWAY_UP
0.00000 0.02548 0.05680MARKEY_RB1_CHRONIC_LOF_DN
0.00000 0.00148 0.00710SMID_BREAST_CANCER_LUMINAL_B_DN
0.00269 0.00000 0.00027ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00573 0.00097 0.16491NOJIMA_SFRP2_TARGETS_DN
0.05857 0.05580 0.12159NETPATH_TGFBETA_RECEPTOR_PATHWAY_DOWN
0.04018 0.00000 0.02960AMIT_SERUM_RESPONSE_120_MCF10A
0.07466 0.17340 0.06724FURUKAWA_DUSP6_TARGETS_PCI35_UP
0.15614 0.00673 0.00002BROWNE_HCMV_INFECTION_2HR_UP
0.00020 0.16479 0.06647VANTVEER_BREAST_CANCER_ESR1_DN
0.10047 0.06284 0.16848CORUM_REL-MAP3K8-RELA-TNIP2-PAPOLA_COMPLEX
0.00000 0.01117 0.11981LEE_LIVER_CANCER_MYC_E2F1_UP
0.17152 0.00270 0.02538SESTO_RESPONSE_TO_UV_C3
0.02049 0.04779 0.16037BIOCARTA_IL17_PATHWAY
0.00000 0.00000 0.00218VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00000 0.00068 0.04896BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.02731 0.14409 0.00028REACTOME_DEATH_RECEPTOR_SIGNALLING
0.00175 0.00000 0.00007GEISS_RESPONSE_TO_DSRNA_UP
0.00015 0.00007 0.03950GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.07476 0.13034 0.02164NCI_P53DOWNSTREAMPATHWAY
0.00221 0.00226 0.00499SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1
0.19549 0.13627 0.14498CORUM_IKBEPSILON-RELA-CREL_COMPLEX
0.00584 0.13679 0.00001ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.09979 0.00000 0.00013ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.00003 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.00043 0.15514 0.08530GRUETZMANN_PANCREATIC_CANCER_UP
0.01548 0.12290 0.13315ROZANOV_MMP14_TARGETS_UP
0.00053 0.00004 0.02420ZHU_CMV_ALL_UP
0.00000 0.00219 0.09337KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.16268 0.00041 0.01148OKUMURA_INFLAMMATORY_RESPONSE_LPS
0.04003 0.19256 0.09557KEGG_APOPTOSIS
0.09234 0.14794 0.10120NATSUME_RESPONSE_TO_INTERFERON_BETA_UP
0.16701 0.06790 0.02494CORUM_NFKB1-NFKB2-REL-RELA-RELB_COMPLEX
0.00021 0.00168 0.00243LEE_LIVER_CANCER_HEPATOBLAST
0.00040 0.00000 0.00002NAGASHIMA_EGF_SIGNALING_UP
0.11440 0.04380 0.04277AMIT_DELAYED_EARLY_GENES
0.00153 0.02107 0.11089KEGG_TYPE_I_DIABETES_MELLITUS
0.00143 0.00000 0.09974HUANG_DASATINIB_RESISTANCE_UP
0.00033 0.00004 0.19807CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN
0.02646 0.00000 0.00027AMIT_EGF_RESPONSE_60_MCF10A
0.00358 0.00008 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00000 0.00000 0.00195KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00013 0.00028 0.00001CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.00123 0.00145 0.00000MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.00488 0.00000 0.00010OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.00021 0.00508 0.01991SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.01232 0.02593 0.00131LEONARD_HYPOXIA
0.04866 0.17291 0.18620REACTOME_SIGNAL_AMPLIFICATION
0.04644 0.05832 0.15184CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN
0.00000 0.00013 0.00495ZHANG_INTERFERON_RESPONSE
0.16308 0.11765 0.00240SESTO_RESPONSE_TO_UV_C1
0.00006 0.14131 0.06140LEE_LIVER_CANCER_MYC_TGFA_UP
0.00000 0.01017 0.00017CROONQUIST_STROMAL_STIMULATION_UP
0.03101 0.00037 0.00031HALMOS_CEBPA_TARGETS_UP
0.01150 0.00041 0.11574WU_CELL_MIGRATION
0.00000 0.00000 0.15257WALLACE_PROSTATE_CANCER_RACE_UP
0.00127 0.07586 0.00091SAGIV_CD24_TARGETS_DN
0.01431 0.11103 0.04849KEGG_ECM_RECEPTOR_INTERACTION
0.00000 0.00041 0.02984KIM_LRRC3B_TARGETS
0.00147 0.00038 0.00881HORIUCHI_WTAP_TARGETS_UP
0.00000 0.08414 0.08331WIELAND_UP_BY_HBV_INFECTION
0.05380 0.01063 0.00349ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.00000 0.00000 0.14135WOO_LIVER_CANCER_RECURRENCE_UP
0.06062 0.09717 0.00816ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP
0.03161 0.15756 0.00768ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP
0.18500 0.00009 0.02760MAHADEVAN_RESPONSE_TO_MP470_DN
0.00000 0.01065 0.08542CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN
0.00000 0.00028 0.00512UROSEVIC_RESPONSE_TO_IMIQUIMOD
0.01019 0.00015 0.15521KEGG_JAK_STAT_SIGNALING_PATHWAY
0.00160 0.00029 0.00003HARRIS_HYPOXIA
0.02531 0.00570 0.18259NETPATH_KIT_RECEPTOR_PATHWAY_UP
0.00030 0.00056 0.00222DER_IFN_BETA_RESPONSE_UP
0.01570 0.02878 0.01727KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP
0.00144 0.00299 0.00448DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.04697 0.00047 0.00347BIOCARTA_CYTOKINE_PATHWAY
0.01151 0.01385 0.00573SEIKE_LUNG_CANCER_POOR_SURVIVAL
0.00053 0.00020 0.13279TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN
0.00000 0.00003 0.00000BASSO_CD40_SIGNALING_UP
0.01499 0.01619 0.04261MUELLER_METHYLATED_IN_GLIOBLASTOMA
0.00005 0.09745 0.16807NCI_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
0.00161 0.00008 0.01502MARZEC_IL2_SIGNALING_UP
0.00648 0.00000 0.00002NAGASHIMA_NRG1_SIGNALING_UP
0.00003 0.00008 0.02994SOUCEK_MYC_TARGETS
0.17707 0.00004 0.06809TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.07345 0.12784 0.03840ZERBINI_RESPONSE_TO_SULINDAC_UP
0.16431 0.07987 0.11869SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN
0.00434 0.06088 0.00878WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP
0.00696 0.13847 0.00103FRIDMAN_SENESCENCE_UP
0.12793 0.00013 0.01404CROMER_TUMORIGENESIS_UP
0.09080 0.01749 0.11264NCI_PTP1BPATHWAY
0.00277 0.06249 0.00336IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP
0.02731 0.03241 0.19091WU_HBX_TARGETS_2_DN
0.01457 0.09144 0.17531NETPATH_B_CELL_RECEPTOR_PATHWAY_UP
0.00029 0.00000 0.00002MAHADEVAN_RESPONSE_TO_MP470_UP
0.04168 0.14877 0.14322CORUM_ITGA2B-ITGB3-CD47-SRC_COMPLEX
0.00000 0.00021 0.08690ZHAN_MULTIPLE_MYELOMA_LB_DN
0.00947 0.00050 0.00002FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.01590 0.19083 0.00010BIOCARTA_TID_PATHWAY
0.14892 0.00353 0.15531SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM
0.00696 0.00000 0.00028BILD_HRAS_ONCOGENIC_SIGNATURE
0.00000 0.00000 0.04172SANA_RESPONSE_TO_IFNG_UP
0.00001 0.00000 0.00005LIANG_SILENCED_BY_METHYLATION_2
0.01097 0.02597 0.00085DAUER_STAT3_TARGETS_UP
0.00000 0.00000 0.15088NETPATH_IL_3_PATHWAY_UP
0.00000 0.01693 0.00027KEGG_LEISHMANIA_INFECTION
0.00003 0.00000 0.03716NETPATH_IL_6_PATHWAY_UP
0.00000 0.00389 0.00312DER_IFN_ALPHA_RESPONSE_UP
0.08841 0.02115 0.01027WANG_ESOPHAGUS_CANCER_PROGRESSION_UP
0.02293 0.00739 0.02293WU_HBX_TARGETS_1_UP
0.00705 0.00060 0.11486BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.01709 0.00074 0.00550CHEN_HOXA5_TARGETS_9HR_UP
0.03944 0.01385 0.00228DAZARD_UV_RESPONSE_CLUSTER_G2
0.00023 0.00009 0.03104EINAV_INTERFERON_SIGNATURE_IN_CANCER
0.00000 0.00014 0.00017MCLACHLAN_DENTAL_CARIES_DN
0.00009 0.01133 0.05771KEGG_ALLOGRAFT_REJECTION
0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00007 0.00030 0.00002GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.06066 0.00226 0.03175CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00000 0.00000 0.06119ZHU_CMV_8_HR_UP
0.03251 0.02071 0.00969BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.03146 0.00004 0.00030BIOCARTA_INFLAM_PATHWAY
0.00000 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.00000 0.00000 0.00512MOSERLE_IFNA_RESPONSE
0.00000 0.00318 0.10440NCI_IL27PATHWAY
0.15854 0.00026 0.00002SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.00000 0.00000 0.09494FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.00639 0.13527 0.00861BIOCARTA_ASBCELL_PATHWAY
0.00757 0.00011 0.00005ONDER_CDH1_TARGETS_2_DN
0.09820 0.00109 0.00013SENESE_HDAC1_TARGETS_UP
0.03006 0.08106 0.08512LIU_TARGETS_OF_VMYB_VS_CMYB_DN
0.00262 0.00006 0.00011HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00039 0.11880 0.19863ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP
0.00029 0.00360 0.06875SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2
0.16501 0.04175 0.12829VICENT_METASTASIS_DN
0.13365 0.00000 0.00002KIM_WT1_TARGETS_UP
0.09963 0.00039 0.01005SENESE_HDAC3_TARGETS_UP
0.00000 0.00858 0.03885KEGG_CHEMOKINE_SIGNALING_PATHWAY
0.00177 0.04226 0.08753FUJII_YBX1_TARGETS_UP
0.00100 0.00917 0.11601CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN
0.01044 0.00805 0.01678KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.02814 0.00000 0.02749UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.01646 0.02133 0.00558XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR
0.12303 0.14087 0.00633BIOCARTA_KERATINOCYTE_PATHWAY
0.00000 0.00209 0.19067JISON_SICKLE_CELL_DISEASE_UP
0.00024 0.00695 0.02115BIOCARTA_GRANULOCYTES_PATHWAY
0.11079 0.07459 0.03244LINDSTEDT_DENDRITIC_CELL_MATURATION_C
0.00356 0.00517 0.00146XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP
0.14492 0.00020 0.00711DASU_IL6_SIGNALING_UP
0.04510 0.00017 0.15685ELVIDGE_HYPOXIA_BY_DMOG_UP
0.15067 0.00030 0.11240HUPER_BREAST_BASAL_VS_LUMINAL_UP
0.00001 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00890 0.14627 0.10139NCI_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS
0.00511 0.00000 0.00011OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.10538 0.05022 0.00002ZUCCHI_METASTASIS_DN
0.10827 0.11523 0.01010SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN
0.00921 0.00039 0.03515SMID_BREAST_CANCER_BASAL_UP
0.07569 0.00119 0.00044PRAMOONJAGO_SOX4_TARGETS_UP
0.05114 0.00000 0.06556PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.06398 0.14838 0.03555YAMASHITA_METHYLATED_IN_PROSTATE_CANCER