BICLUSTER_ID : UPREG-72
PATHOGENS /3/ : pseudomonas aeruginosa,lactobacillus acidophilus,mycobacterium tuberculosis
TARGETS /16/ : CCL20, PDE4B, CCL2, CD40, TNFRSF1B, CASP7, GCH1, SAT1, CXCL10, NFKB1, IFNGR2, IL6, IL1B, PTGS2, ICAM1, CASP1
Gene SetLeading Edge Genes
NETPATH TNF ALPHA PATHWAY UPPSMB8, OPTN, GCH1, INHBA, CXCL2, RELB, SOD2, CXCL10, CFLAR, NFKB1, SGK, TNIP1, TAPBPL, CXCL1, JUNB, BCL3, TNFAIP2, TNFAIP3, IL15RA, ICAM1, JAG1, IRF1, NFKB2, NCK1, NFKBIE, CCL2, ISGF3G, TNFRSF1B, CASP7, BIRC3, IFNGR2, TRIM21, IL6, PTGS2, DUSP1
NETPATH IL 2 PATHWAY UPPFKFB3, PDE4B, ISGF3G, TNFRSF1B, NMI, TRAFD1, IL4R, IFI44, CFLAR, IFIT1, SGK, NFKB1, B4GALT5, KLF6, SP100, DUSP5, TRIM21, IFITM3, IL6, IL1B, ICAM1, CASP1, IRF1
NETPATH IL 1 PATHWAY UPNFKB1, BIRC3, CCL20, CXCL1, NFKBIE, IL6, PTGS2, INHBA, ICAM1, CXCL2, SOD2
NCI IL23PATHWAYNFKB1, IL6, IL1B, CXCL1, CCL2, STAT5A
NETPATH IL 4 PATHWAY DOWNCCL20, GADD45B, CDKN1A, CCL2, PTGS2, ICAM1, CXCL2, IRF1
NCI IL1PATHWAYSQSTM1, NFKB1, IL1RN, IL1B, CASP1, MYD88
NETPATH IL 5 PATHWAY UPNFKB1, SGK, PLSCR1, REL, BIRC3, DUSP5, NFKB2, NFKBIE, CCL2, HIF1A, ICAM1, RELB, MYD88
NCI TNFPATHWAYNFKB1, SQSTM1, BIRC3, TNFAIP3, CYLD, TNFRSF1B
GERY CEBP TARGETSGADD45B, CXCL1, EREG, JUNB, CD47, TNFAIP6, ATF3, GCH1, SAT1, DUSP1
ST TUMOR NECROSIS FACTOR PATHWAYNFKB1, BIRC3, TNFAIP3, NFKB2, NFKBIE, TNFRSF1B, CFLAR
NCI IL12 2PATHWAYNFKB1, GADD45B, IL1B, NFKB2, RELB, STAT5A, TYK2
NCI CD40 PATHWAYNFKB1, BIRC3, TNFAIP3, TRAF2, CD40, STAT5A
NCI NFKAPPABALTERNATIVEPATHWAYNFKB1, NFKB2, RELB
CORUM CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2 COMPLEXNFKB1, TNIP1, NFKB2, NFKBIE
NCI NFKAPPABCANONICALPATHWAYNFKB1, TNFAIP3, CYLD
ST B CELL ANTIGEN RECEPTOR
BIOCARTA IL10 PATHWAY
REACTOME SIGNALING BY PDGF
BIOCARTA PML PATHWAY
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
BIOCARTA STEM PATHWAY
NETPATH IL 9 PATHWAY UP
BIOCARTA NFKB PATHWAY
MAHAJAN RESPONSE TO IL1A UP
WEINMANN ADAPTATION TO HYPOXIA DN
BIOCARTA IL6 PATHWAY
BOYAULT LIVER CANCER SUBCLASS G5 DN
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP
LINDSTEDT DENDRITIC CELL MATURATION B
BIOCARTA IL1R PATHWAY
KRASNOSELSKAYA ILF3 TARGETS UP
BIOCARTA RELA PATHWAY
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
NETPATH IL 1 PATHWAY
MORI LARGE PRE BII LYMPHOCYTE DN
ELVIDGE HYPOXIA UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
BOWIE RESPONSE TO EXTRACELLULAR MATRIX
NETPATH IL 7 PATHWAY UPSLC3A2, FAS, CXCL1, CXCL2, LAG3, STAT5A
BIOCARTA NKT PATHWAY
MITSIADES RESPONSE TO APLIDIN UP
BROWNE INTERFERON RESPONSIVE GENES
NCI IL6 7PATHWAY
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
CONRAD GERMLINE STEM CELL
ROETH TERT TARGETS UP
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION SUSTAINDED IN ERYTHROCYTE UP
HINATA NFKB TARGETS KERATINOCYTE UP
NCI TRAIL SIGNALING
KOKKINAKIS METHIONINE DEPRIVATION 96HR UP
MARKEY RB1 ACUTE LOF UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
VART KSHV INFECTION ANGIOGENIC MARKERS UP
AMIT SERUM RESPONSE 60 MCF10A
BIOCARTA LYM PATHWAY
GILMORE CORE NFKB PATHWAY
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
BIOCARTA IL22BP PATHWAY
TSAI RESPONSE TO IONIZING RADIATION
DIRMEIER LMP1 RESPONSE EARLY
DER IFN GAMMA RESPONSE UP
KEGG INTESTINAL IMMUNE NETWORK FOR IGA PRODUCTION
LIU VAV3 PROSTATE CARCINOGENESIS UP
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES
SEITZ NEOPLASTIC TRANSFORMATION BY 8P DELETION UP
BIOCARTA CD40 PATHWAY
BENNETT SYSTEMIC LUPUS ERYTHEMATOSUS
CORUM NFKB1-NFKB2-RELA-RELB COMPLEX
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP
ONDER CDH1 TARGETS 3 DN
ZHOU INFLAMMATORY RESPONSE LIVE UP
AMIT EGF RESPONSE 120 HELA
BIOCARTA RANKL PATHWAY
NAKAYAMA SOFT TISSUE TUMORS PCA1 UP
MCLACHLAN DENTAL CARIES UP
WINTER HYPOXIA METAGENE
NETPATH TNF ALPHA PATHWAY
NCI TNF SIGNALING
NEWMAN ERCC6 TARGETS UP
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK KPNA3 NFKB2 NFKBIB REL IKBKG NFKB1 NFKBIE RELB NFKBIA RELA TNIP2
PODAR RESPONSE TO ADAPHOSTIN UP
SHAFFER IRF4 TARGETS IN PLASMA CELL VS MATURE B LYMPHOCYTE
ISHIKAWA STING SIGNALING
CORUM ABIN2-NFKB1-MAP3K8 COMPLEX
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
KYNG DNA DAMAGE UP
FOSTER INFLAMMATORY RESPONSE LPS DN
LEE LIVER CANCER E2F1 UP
TAVOR CEBPA TARGETS UP
GAURNIER PSMD4 TARGETS
REACTOME HUMAN TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX
HELLER SILENCED BY METHYLATION UP
GRANDVAUX IFN RESPONSE NOT VIA IRF3
OSAWA TNF TARGETS
BOWIE RESPONSE TO TAMOXIFEN
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
MARKEY RB1 CHRONIC LOF DN
NCI AMB2 NEUTROPHILS PATHWAY
SMID BREAST CANCER LUMINAL B DN
ZHOU INFLAMMATORY RESPONSE LPS UP
NOJIMA SFRP2 TARGETS DN
AMIT SERUM RESPONSE 120 MCF10A
FURUKAWA DUSP6 TARGETS PCI35 UP
BROWNE HCMV INFECTION 2HR UP
LEE LIVER CANCER MYC E2F1 UP
SESTO RESPONSE TO UV C3
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
REACTOME DEATH RECEPTOR SIGNALLING
GEISS RESPONSE TO DSRNA UP
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX RPL6 RPL30 RPS13 CHUK DDX3X NFKB2 NFKBIB REL IKBKG NFKB1 MAP3K8 RELB GLG1 NFKBIA RELA TNIP2 GTF2I
REACTOME VIRAL DSRNA TLR3 TRIF COMPLEX ACTIVATES RIP1
ZHOU INFLAMMATORY RESPONSE FIMA UP
TIAN TNF SIGNALING VIA NFKB
GRUETZMANN PANCREATIC CANCER UP
HUMMEL BURKITTS LYMPHOMA DN
WANG BARRETTS ESOPHAGUS AND ESOPHAGUS CANCER UP
ZHU CMV ALL UP
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY
KEGG APOPTOSIS
NATSUME RESPONSE TO INTERFERON BETA UP
CORUM NFKB1-NFKB2-REL-RELA-RELB COMPLEX
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
KEGG TYPE I DIABETES MELLITUS
HUANG DASATINIB RESISTANCE UP
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN
AMIT EGF RESPONSE 60 MCF10A
HINATA NFKB TARGETS FIBROBLAST UP
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
RHEIN ALL GLUCOCORTICOID THERAPY UP
MISSIAGLIA REGULATED BY METHYLATION UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
LEONARD HYPOXIA
BIOCARTA EPONFKB PATHWAY
ZHANG INTERFERON RESPONSE
BROWNE HCMV INFECTION 12HR UP
SESTO RESPONSE TO UV C1
NCI NFKAPPABATYPICALPATHWAY
CROONQUIST STROMAL STIMULATION UP
WALLACE PROSTATE CANCER RACE UP
SIMBULAN UV RESPONSE NORMAL UP
KIM LRRC3B TARGETS
HORIUCHI WTAP TARGETS UP
WIELAND UP BY HBV INFECTION
ONDER CDH1 SIGNALING VIA CTNNB1
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN UP
MAHADEVAN RESPONSE TO MP470 DN
BIOCARTA SODD PATHWAY
UROSEVIC RESPONSE TO IMIQUIMOD
BIOCARTA TH1TH2 PATHWAY
HARRIS HYPOXIA
DER IFN BETA RESPONSE UP
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
DIRMEIER LMP1 RESPONSE LATE UP
NCI REGULATED PROTEOLYSIS OF P75NTR
KEGG ADIPOCYTOKINE SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
XU RESPONSE TO TRETINOIN AND NSC682994 UP
NCI IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL
MARZEC IL2 SIGNALING UP
NAGASHIMA NRG1 SIGNALING UP
SOUCEK MYC TARGETS
BIOCARTA IL5 PATHWAY
BIOCARTA EPO PATHWAY
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
VERRECCHIA RESPONSE TO TGFB1 C2
ZERBINI RESPONSE TO SULINDAC UP
KEGG B CELL RECEPTOR SIGNALING PATHWAY
IZADPANAH STEM CELL ADIPOSE VS BONE UP
WU HBX TARGETS 2 DN
NETPATH B CELL RECEPTOR PATHWAY UP
MAHADEVAN RESPONSE TO MP470 UP
NCI DOWNSTREAM TCR SIGNALING
ZHAN MULTIPLE MYELOMA LB DN
FERRARI RESPONSE TO FENRETINIDE UP
KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY
BIOCARTA TID PATHWAY
NETPATH WNT PATHWAY DOWN
SHAFFER IRF4 MULTIPLE MYELOMA PROGRAM
BILD HRAS ONCOGENIC SIGNATURE
SANA RESPONSE TO IFNG UP
ZHAN MULTIPLE MYELOMA SPIKED
LIANG SILENCED BY METHYLATION 2
DAUER STAT3 TARGETS UP
NETPATH IL 3 PATHWAY UP
KEGG LEISHMANIA INFECTION
NETPATH IL 6 PATHWAY UPSGK, GADD45B, CXCL1, JUNB, BCL3, MAP3K8, NMI, TNFRSF11B, IRF1
DER IFN ALPHA RESPONSE UP
SCHEIDEREIT IKK TARGETS
LEE LIVER CANCER ACOX1 UP
EINAV INTERFERON SIGNATURE IN CANCER
CHEN HOXA5 TARGETS 9HR UP
DAZARD UV RESPONSE CLUSTER G2
BIOCARTA DEATH PATHWAY
MCLACHLAN DENTAL CARIES DN
KEGG ALLOGRAFT REJECTION
SEKI INFLAMMATORY RESPONSE LPS UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
BIOCARTA STRESS PATHWAY
PARK TRETINOIN RESPONSE AND PML RARA FUSION
ZHU CMV 8 HR UP
BIOCARTA INFLAM PATHWAY
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP
SANA TNF SIGNALING UP
MOSERLE IFNA RESPONSE
NCI IL27PATHWAY
FOSTER INFLAMMATORY RESPONSE LPS UP
BIOCARTA ASBCELL PATHWAY
NAKAJIMA MAST CELL
ONDER CDH1 TARGETS 2 DN
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
ODONNELL TARGETS OF MYC AND TFRC UP
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 2
REACTOME P75NTR SIGNALS VIA NFKB
KEGG CHEMOKINE SIGNALING PATHWAY
FUJII YBX1 TARGETS UP
KEGG CYTOSOLIC DNA SENSING PATHWAY
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
JISON SICKLE CELL DISEASE UP
BIOCARTA TNFR2 PATHWAY
LINDSTEDT DENDRITIC CELL MATURATION C
MORI IMMATURE B LYMPHOCYTE UP
ELVIDGE HYPOXIA BY DMOG UP
DASU IL6 SIGNALING UP
BIOCARTA TOLL PATHWAY
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
BOHN PRIMARY IMMUNODEFICIENCY SYNDROM DN
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
ZUCCHI METASTASIS DN
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP
NCI ACTIVATION OF PRO CASPASE 8
PRAMOONJAGO SOX4 TARGETS UP
KOBAYASHI RESPONSE TO ROMIDEPSIN
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
lactobacillus acidophiluspseudomonas aeruginosa fdr440mycobacterium tuberculosisGeneSet Name
0.09704 0.00318 0.00534NETPATH_TNF_ALPHA_PATHWAY_UP
0.01173 0.00843 0.00008NETPATH_IL_2_PATHWAY_UP
0.00114 0.00000 0.00602NETPATH_IL_1_PATHWAY_UP
0.00000 0.01471 0.00126NCI_IL23PATHWAY
0.00012 0.00000 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.02751 0.07208 0.01300NCI_IL1PATHWAY
0.01533 0.00726 0.00000NETPATH_IL_5_PATHWAY_UP
0.00465 0.03239 0.01252NCI_TNFPATHWAY
0.00427 0.00131 0.00000GERY_CEBP_TARGETS
0.00006 0.00001 0.00010ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00000 0.06732 0.00051NCI_IL12_2PATHWAY
0.02747 0.00530 0.01575NCI_CD40_PATHWAY
0.08864 0.01530 0.00869NCI_NFKAPPABALTERNATIVEPATHWAY
0.01629 0.00017 0.00431CORUM_CHUK-NFKB2-REL-IKBKG-SPAG9-NFKB1-NFKBIE-COPB2-TNIP1-NFKBIA-RELA-TNIP2_COMPLEX
0.00905 0.01645 0.00572NCI_NFKAPPABCANONICALPATHWAY
0.06207 0.01108 0.02207ST_B_CELL_ANTIGEN_RECEPTOR
0.00000 0.01645 0.00336BIOCARTA_IL10_PATHWAY
0.07863 0.02137 0.12627REACTOME_SIGNALING_BY_PDGF
0.01418 0.00518 0.02320BIOCARTA_PML_PATHWAY
0.00008 0.01700 0.00002GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.01289 0.01042 0.14979BIOCARTA_STEM_PATHWAY
0.01316 0.04269 0.08229NETPATH_IL_9_PATHWAY_UP
0.01221 0.00100 0.00073BIOCARTA_NFKB_PATHWAY
0.00430 0.00044 0.00132MAHAJAN_RESPONSE_TO_IL1A_UP
0.05378 0.01567 0.03354WEINMANN_ADAPTATION_TO_HYPOXIA_DN
0.13369 0.09012 0.06335BIOCARTA_IL6_PATHWAY
0.02379 0.02290 0.00000BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN
0.00000 0.00068 0.00000ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP
0.00000 0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.02532 0.06380 0.00118BIOCARTA_IL1R_PATHWAY
0.00414 0.11846 0.00000KRASNOSELSKAYA_ILF3_TARGETS_UP
0.01632 0.00063 0.03322BIOCARTA_RELA_PATHWAY
0.00034 0.00000 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00000 0.00003 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.10592 0.00311 0.03544NETPATH_IL_1_PATHWAY
0.05987 0.05973 0.01956MORI_LARGE_PRE_BII_LYMPHOCYTE_DN
0.10353 0.16459 0.00052ELVIDGE_HYPOXIA_UP
0.00648 0.00064 0.00217IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00081 0.15015 0.00000AMIT_EGF_RESPONSE_40_HELA
0.00070 0.03539 0.00000BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX
0.06237 0.00003 0.00856NETPATH_IL_7_PATHWAY_UP
0.00487 0.01701 0.00137BIOCARTA_NKT_PATHWAY
0.18043 0.01817 0.00000MITSIADES_RESPONSE_TO_APLIDIN_UP
0.00000 0.00002 0.00000BROWNE_INTERFERON_RESPONSIVE_GENES
0.12322 0.14730 0.00288NCI_IL6_7PATHWAY
0.09352 0.00052 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00372 0.11741 0.00000TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.17180 0.08773 0.09937CONRAD_GERMLINE_STEM_CELL
0.00492 0.10447 0.00015ROETH_TERT_TARGETS_UP
0.06413 0.06129 0.00199TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP
0.00000 0.00000 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.02015 0.01306 0.02528NCI_TRAIL__SIGNALING
0.13048 0.05096 0.02144KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP
0.00000 0.01820 0.00000MARKEY_RB1_ACUTE_LOF_UP
0.00000 0.00034 0.00060KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00138 0.08419 0.01566VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP
0.17039 0.01060 0.00001AMIT_SERUM_RESPONSE_60_MCF10A
0.09025 0.01705 0.18330BIOCARTA_LYM_PATHWAY
0.00978 0.00085 0.00092GILMORE_CORE_NFKB_PATHWAY
0.00089 0.00021 0.00000NUYTTEN_EZH2_TARGETS_UP
0.00233 0.00513 0.00002DUTTA_APOPTOSIS_VIA_NFKB
0.00107 0.08742 0.01147BIOCARTA_IL22BP_PATHWAY
0.18848 0.04793 0.00008TSAI_RESPONSE_TO_IONIZING_RADIATION
0.00007 0.00002 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00091 0.00011 0.00000DER_IFN_GAMMA_RESPONSE_UP
0.00200 0.03514 0.00469KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION
0.02070 0.00848 0.00067LIU_VAV3_PROSTATE_CARCINOGENESIS_UP
0.00017 0.00009 0.00176REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
0.00000 0.05479 0.00000SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP
0.03092 0.00500 0.01971BIOCARTA_CD40_PATHWAY
0.00000 0.06522 0.00000BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS
0.11966 0.02079 0.04157CORUM_NFKB1-NFKB2-RELA-RELB_COMPLEX
0.01803 0.02769 0.00000GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP
0.00174 0.00194 0.10086ONDER_CDH1_TARGETS_3_DN
0.00000 0.00010 0.00002ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.09453 0.00068 0.00000AMIT_EGF_RESPONSE_120_HELA
0.00384 0.01277 0.03099BIOCARTA_RANKL_PATHWAY
0.01636 0.05763 0.00000NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP
0.00667 0.00001 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.11168 0.00135 0.00019WINTER_HYPOXIA_METAGENE
0.02931 0.03241 0.07034NETPATH_TNF_ALPHA_PATHWAY
0.04506 0.08510 0.19460NCI_TNF_SIGNALING
0.06163 0.03524 0.00177NEWMAN_ERCC6_TARGETS_UP
0.00206 0.00016 0.00136CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_KPNA3_NFKB2_NFKBIB_REL_IKBKG__NFKB1_NFKBIE_RELB__NFKBIA_RELA_TNIP2
0.00831 0.13382 0.00000PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.12293 0.09246 0.00911SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE
0.01863 0.06552 0.00865ISHIKAWA_STING_SIGNALING
0.11134 0.07172 0.16855CORUM_ABIN2-NFKB1-MAP3K8_COMPLEX
0.08350 0.12253 0.00000GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.08863 0.00132 0.00460KYNG_DNA_DAMAGE_UP
0.00000 0.00037 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00852 0.16834 0.00014LEE_LIVER_CANCER_E2F1_UP
0.10298 0.08516 0.00011TAVOR_CEBPA_TARGETS_UP
0.00000 0.00002 0.00000GAURNIER_PSMD4_TARGETS
0.03056 0.00194 0.00246REACTOME_HUMAN_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX
0.00489 0.01964 0.00000HELLER_SILENCED_BY_METHYLATION_UP
0.00046 0.04085 0.00000GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3
0.12892 0.00149 0.07502OSAWA_TNF_TARGETS
0.00010 0.04904 0.00000BOWIE_RESPONSE_TO_TAMOXIFEN
0.01124 0.01084 0.00117SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.03135 0.05680 0.01556MARKEY_RB1_CHRONIC_LOF_DN
0.18674 0.00315 0.09678NCI_AMB2_NEUTROPHILS_PATHWAY
0.07352 0.00710 0.07952SMID_BREAST_CANCER_LUMINAL_B_DN
0.00000 0.00027 0.00000ZHOU_INFLAMMATORY_RESPONSE_LPS_UP
0.00035 0.16491 0.00051NOJIMA_SFRP2_TARGETS_DN
0.01424 0.02960 0.00013AMIT_SERUM_RESPONSE_120_MCF10A
0.00918 0.06724 0.00001FURUKAWA_DUSP6_TARGETS_PCI35_UP
0.06476 0.00002 0.00000BROWNE_HCMV_INFECTION_2HR_UP
0.00992 0.11981 0.00022LEE_LIVER_CANCER_MYC_E2F1_UP
0.02540 0.02538 0.00000SESTO_RESPONSE_TO_UV_C3
0.03043 0.00218 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.03083 0.04896 0.00000BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.00039 0.00028 0.01374REACTOME_DEATH_RECEPTOR_SIGNALLING
0.00027 0.00007 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.00001 0.03950 0.00000GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.12179 0.00499 0.00666SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1
0.03188 0.00282 0.00487CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_RPL6_RPL30_RPS13_CHUK_DDX3X_NFKB2_NFKBIB_REL_IKBKG_NFKB1_MAP3K8_RELB_GLG1_NFKBIA_RELA_TNIP2__GTF2I
0.09858 0.00313 0.00550REACTOME_VIRAL_DSRNA_TLR3_TRIF_COMPLEX_ACTIVATES_RIP1
0.00018 0.00013 0.00047ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.00000 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.09339 0.08530 0.00008GRUETZMANN_PANCREATIC_CANCER_UP
0.02581 0.01003 0.00035HUMMEL_BURKITTS_LYMPHOMA_DN
0.08184 0.00196 0.06708WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_UP
0.00466 0.02420 0.00000ZHU_CMV_ALL_UP
0.00000 0.09337 0.00000KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.01718 0.09557 0.16900KEGG_APOPTOSIS
0.00828 0.10120 0.00485NATSUME_RESPONSE_TO_INTERFERON_BETA_UP
0.05429 0.02494 0.05523CORUM_NFKB1-NFKB2-REL-RELA-RELB_COMPLEX
0.04137 0.00243 0.13990LEE_LIVER_CANCER_HEPATOBLAST
0.05878 0.00002 0.00000NAGASHIMA_EGF_SIGNALING_UP
0.00022 0.11089 0.06667KEGG_TYPE_I_DIABETES_MELLITUS
0.17300 0.09974 0.00030HUANG_DASATINIB_RESISTANCE_UP
0.03196 0.19807 0.00205CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN
0.00978 0.00027 0.00004AMIT_EGF_RESPONSE_60_MCF10A
0.01167 0.00000 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00000 0.00195 0.00225KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.02479 0.00001 0.00002CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.09913 0.11161 0.00003RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP
0.00001 0.00000 0.00000MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.00598 0.00010 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.05078 0.00131 0.01105LEONARD_HYPOXIA
0.08632 0.00002 0.00738BIOCARTA_EPONFKB_PATHWAY
0.00000 0.00495 0.00000ZHANG_INTERFERON_RESPONSE
0.19772 0.09407 0.00050BROWNE_HCMV_INFECTION_12HR_UP
0.10290 0.00240 0.01198SESTO_RESPONSE_TO_UV_C1
0.01289 0.10751 0.01619NCI_NFKAPPABATYPICALPATHWAY
0.04711 0.00017 0.00025CROONQUIST_STROMAL_STIMULATION_UP
0.00000 0.15257 0.00000WALLACE_PROSTATE_CANCER_RACE_UP
0.01522 0.01311 0.04602SIMBULAN_UV_RESPONSE_NORMAL_UP
0.00009 0.02984 0.00000KIM_LRRC3B_TARGETS
0.00495 0.00881 0.00000HORIUCHI_WTAP_TARGETS_UP
0.00048 0.08331 0.00000WIELAND_UP_BY_HBV_INFECTION
0.05066 0.00349 0.01211ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.00374 0.00768 0.00000ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP
0.00321 0.02760 0.00000MAHADEVAN_RESPONSE_TO_MP470_DN
0.01240 0.00780 0.10024BIOCARTA_SODD_PATHWAY
0.00000 0.00512 0.00000UROSEVIC_RESPONSE_TO_IMIQUIMOD
0.00113 0.00729 0.13686BIOCARTA_TH1TH2_PATHWAY
0.18721 0.00003 0.00067HARRIS_HYPOXIA
0.00144 0.00222 0.00000DER_IFN_BETA_RESPONSE_UP
0.09320 0.01727 0.00022KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP
0.00593 0.00448 0.00000DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.09243 0.00027 0.00003DIRMEIER_LMP1_RESPONSE_LATE_UP
0.12594 0.19099 0.17760NCI_REGULATED_PROTEOLYSIS_OF_P75NTR
0.10763 0.00498 0.13484KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY
0.00000 0.00000 0.00000BASSO_CD40_SIGNALING_UP
0.04511 0.02705 0.02074XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP
0.00923 0.16807 0.01857NCI_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
0.15147 0.01502 0.00127MARZEC_IL2_SIGNALING_UP
0.02256 0.00002 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.00010 0.02994 0.02521SOUCEK_MYC_TARGETS
0.02266 0.14847 0.05187BIOCARTA_IL5_PATHWAY
0.09192 0.11155 0.07946BIOCARTA_EPO_PATHWAY
0.02438 0.06809 0.00228TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.14987 0.03252 0.02209VERRECCHIA_RESPONSE_TO_TGFB1_C2
0.18728 0.03840 0.04554ZERBINI_RESPONSE_TO_SULINDAC_UP
0.17812 0.19658 0.00317KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY
0.19490 0.00336 0.00047IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP
0.02392 0.19091 0.10873WU_HBX_TARGETS_2_DN
0.17292 0.17531 0.00218NETPATH_B_CELL_RECEPTOR_PATHWAY_UP
0.00272 0.00002 0.00004MAHADEVAN_RESPONSE_TO_MP470_UP
0.16042 0.08727 0.00478NCI_DOWNSTREAM_TCR_SIGNALING
0.00182 0.08690 0.00000ZHAN_MULTIPLE_MYELOMA_LB_DN
0.15133 0.00002 0.00018FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00006 0.03234 0.00002KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.09391 0.00010 0.01104BIOCARTA_TID_PATHWAY
0.12242 0.07767 0.14069NETPATH_WNT_PATHWAY_DOWN
0.00812 0.15531 0.00240SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM
0.00628 0.00028 0.00000BILD_HRAS_ONCOGENIC_SIGNATURE
0.00000 0.04172 0.00000SANA_RESPONSE_TO_IFNG_UP
0.09672 0.08608 0.00289ZHAN_MULTIPLE_MYELOMA_SPIKED
0.00000 0.00005 0.00000LIANG_SILENCED_BY_METHYLATION_2
0.00259 0.00085 0.00000DAUER_STAT3_TARGETS_UP
0.00372 0.15088 0.00171NETPATH_IL_3_PATHWAY_UP
0.00174 0.00027 0.00007KEGG_LEISHMANIA_INFECTION
0.00006 0.03716 0.00000NETPATH_IL_6_PATHWAY_UP
0.00000 0.00312 0.00000DER_IFN_ALPHA_RESPONSE_UP
0.10666 0.00766 0.00738SCHEIDEREIT_IKK_TARGETS
0.05143 0.13286 0.00473LEE_LIVER_CANCER_ACOX1_UP
0.00000 0.03104 0.00000EINAV_INTERFERON_SIGNATURE_IN_CANCER
0.04051 0.00550 0.00006CHEN_HOXA5_TARGETS_9HR_UP
0.06213 0.00228 0.01541DAZARD_UV_RESPONSE_CLUSTER_G2
0.13894 0.00012 0.02502BIOCARTA_DEATH_PATHWAY
0.01242 0.00017 0.00001MCLACHLAN_DENTAL_CARIES_DN
0.00026 0.05771 0.00549KEGG_ALLOGRAFT_REJECTION
0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00002 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00854 0.03175 0.00028CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.18094 0.06876 0.06124BIOCARTA_STRESS_PATHWAY
0.14509 0.06632 0.00026PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION
0.00000 0.06119 0.00000ZHU_CMV_8_HR_UP
0.00000 0.00030 0.05068BIOCARTA_INFLAM_PATHWAY
0.03405 0.06733 0.00001BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
0.00000 0.00000 0.00000SANA_TNF_SIGNALING_UP
0.00000 0.00512 0.00000MOSERLE_IFNA_RESPONSE
0.00000 0.10440 0.04359NCI_IL27PATHWAY
0.00000 0.09494 0.00000FOSTER_INFLAMMATORY_RESPONSE_LPS_UP
0.01240 0.00861 0.10630BIOCARTA_ASBCELL_PATHWAY
0.05761 0.03210 0.04663NAKAJIMA_MAST_CELL
0.02211 0.00005 0.00500ONDER_CDH1_TARGETS_2_DN
0.11701 0.00011 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.04832 0.19863 0.00736ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP
0.01605 0.06875 0.04041SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2
0.17190 0.01970 0.00334REACTOME_P75NTR_SIGNALS_VIA_NFKB
0.03796 0.03885 0.02902KEGG_CHEMOKINE_SIGNALING_PATHWAY
0.00630 0.08753 0.01288FUJII_YBX1_TARGETS_UP
0.00033 0.01678 0.00059KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
0.03748 0.02749 0.00000UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00011 0.19067 0.00000JISON_SICKLE_CELL_DISEASE_UP
0.00403 0.02358 0.00388BIOCARTA_TNFR2_PATHWAY
0.00318 0.03244 0.15036LINDSTEDT_DENDRITIC_CELL_MATURATION_C
0.01006 0.03187 0.00002MORI_IMMATURE_B_LYMPHOCYTE_UP
0.12346 0.15685 0.00043ELVIDGE_HYPOXIA_BY_DMOG_UP
0.15237 0.00711 0.00006DASU_IL6_SIGNALING_UP
0.07530 0.14412 0.00018BIOCARTA_TOLL_PATHWAY
0.00000 0.00000 0.00002GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.17284 0.18397 0.10077BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_DN
0.00475 0.00011 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.04132 0.00002 0.00039ZUCCHI_METASTASIS_DN
0.01593 0.00131 0.00002BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP
0.00490 0.02766 0.04958NCI_ACTIVATION_OF_PRO_CASPASE_8
0.00031 0.00044 0.00000PRAMOONJAGO_SOX4_TARGETS_UP
0.19533 0.13806 0.00458KOBAYASHI_RESPONSE_TO_ROMIDEPSIN
0.00034 0.06556 0.00000PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN