BICLUSTER_ID : <a href="#qvalue">UPREG-724</a><BR>PATHOGENS /2/ : <a href="http://www.ebi.ac.uk/2can/genomes/bacteria/aggregatibacter actinomycetemcomitans.html">aggregatibacter actinomycetemcomitans</a>,<a href="http://www.ebi.ac.uk/2can/genomes/bacteria/helicobacter pylori.html">helicobacter pylori</a><BR>TARGETS /1/ : <a href=drug-id-and-target-info.html#JUN>JUN</a><BR>
<table border="1">
<tbody>
<tr><th width="300">Gene Set</th><th width="900">Leading Edge Genes</th></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/NETPATH_IL_6_PATHWAY_UP">NETPATH IL 6 PATHWAY UP</a></td><td>GADD45B, CXCL1, <a href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=6204">JUN</a>, HBEGF</td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/MAHADEVAN_RESPONSE_TO_MP470_DN">MAHADEVAN RESPONSE TO MP470 DN</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/NOJIMA_SFRP2_TARGETS_UP">NOJIMA SFRP2 TARGETS UP</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/LEONARD_HYPOXIA">LEONARD HYPOXIA</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/BIOCARTA_STEM_PATHWAY">BIOCARTA STEM PATHWAY</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/DAUER_STAT3_TARGETS_UP">DAUER STAT3 TARGETS UP</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/REACTOME_CLASS_C3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS">REACTOME CLASS C3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/HINATA_NFKB_TARGETS_KERATINOCYTE_UP">HINATA NFKB TARGETS KERATINOCYTE UP</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN">UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/KEGG_GRAFT_VERSUS_HOST_DISEASE">KEGG GRAFT VERSUS HOST DISEASE</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/BIOCARTA_GRANULOCYTES_PATHWAY">BIOCARTA GRANULOCYTES PATHWAY</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/MENSE_HYPOXIA_UP">MENSE HYPOXIA UP</a></td><td>CLK3, PFKFB3, HK2, NDRG1, JMJD1A, VEGF, ENO2, DIDO1, PPFIA4, STC2, ADM, BHLHB2</td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/DAZARD_UV_RESPONSE_CLUSTER_G3">DAZARD UV RESPONSE CLUSTER G3</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/TIAN_TNF_SIGNALING_VIA_NFKB">TIAN TNF SIGNALING VIA NFKB</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/SEKI_INFLAMMATORY_RESPONSE_LPS_UP">SEKI INFLAMMATORY RESPONSE LPS UP</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/ZUCCHI_METASTASIS_DN">ZUCCHI METASTASIS DN</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP">GRAHAM CML QUIESCENT VS CML DIVIDING UP</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP">ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/DIRMEIER_LMP1_RESPONSE_EARLY">DIRMEIER LMP1 RESPONSE EARLY</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/MAHADEVAN_RESPONSE_TO_MP470_UP">MAHADEVAN RESPONSE TO MP470 UP</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/KRIGE_AMINO_ACID_DEPRIVATION">KRIGE AMINO ACID DEPRIVATION</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/PRAMOONJAGO_SOX4_TARGETS_UP">PRAMOONJAGO SOX4 TARGETS UP</a></td><td></td></tr>
<tr><td><a href="http://www.broad.mit.edu/gsea/msigdb/cards/HINATA_NFKB_TARGETS_FIBROBLAST_UP">HINATA NFKB TARGETS FIBROBLAST UP</a></td><td></td></tr>
</tbody>
</table>
<table border="1"rules="all" VSPACE=10>
<tr><th colspan="12"<a name="qvalue">Color legend </a></th></tr>
<tr><th>q-value</th><th>1</th><th>0.2</th><th>0.05</th><th>0.01</th><th>0.001</th><th>0.0001</th></tr>
<tr><th>Color</th><td bgcolor="#ffffff" title="-1"></td><td bgcolor="#fee08b" title="-0.2"></
td><td bgcolor="#fdae61"
title="-0.05"></td><td bgcolor="#f46d43" title="-0.01"></td><td 
bgcolor="#d73027" title="-0.001"></td><td title="-0.0001"
bgcolor="#a50026"></td></tr>
</table>
<table border="1" VSPACE=0>
<table border="1" rules="all">
<caption align="top">TABLE OF Q-VALUES</caption>
<tbody>
<tr><th width="150">helicobacter pylori kx2 npgec</th><th width="150">aggregatibacter actinomycetemcomitans</th><th>GeneSet Name</th></tr>
<tr><td align="center" width="150" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.13630</span></font></td><td align="center" width="150" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.10450</span></font></td><td>NETPATH_IL_6_PATHWAY_UP</td></tr>
<tr><td align="center" width="150" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.09615</span></font></td><td align="center" width="150" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.04315</span></font></td><td>MAHADEVAN_RESPONSE_TO_MP470_DN</td></tr>
<tr><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.03559</span></font></td><td align="center" bgcolor="#f46d43"><font size=1> <span style="background-color:white">0.00977</span></font></td><td>NOJIMA_SFRP2_TARGETS_UP</td></tr>
<tr><td align="center" bgcolor="#f46d43"><font size=1> <span style="background-color:white">0.00289</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.05026</span></font></td><td>LEONARD_HYPOXIA</td></tr>
<tr><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.08374</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.17911</span></font></td><td>BIOCARTA_STEM_PATHWAY</td></tr>
<tr><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.04938</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.10550</span></font></td><td>DAUER_STAT3_TARGETS_UP</td></tr>
<tr><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.06394</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.15487</span></font></td><td>REACTOME_CLASS_C3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS</td></tr>
<tr><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.16190</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.19710</span></font></td><td>HINATA_NFKB_TARGETS_KERATINOCYTE_UP</td></tr>
<tr><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.03267</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.07257</span></font></td><td>UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN</td></tr>
<tr><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.09151</span></font></td><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.02938</span></font></td><td>KEGG_GRAFT_VERSUS_HOST_DISEASE</td></tr>
<tr><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.01885</span></font></td><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.01701</span></font></td><td>BIOCARTA_GRANULOCYTES_PATHWAY</td></tr>
<tr><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.01619</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.12893</span></font></td><td>MENSE_HYPOXIA_UP</td></tr>
<tr><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.19060</span></font></td><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.03993</span></font></td><td>DAZARD_UV_RESPONSE_CLUSTER_G3</td></tr>
<tr><td align="center" bgcolor="#a50026"><font size=1> <span style="background-color:white">0.00000</span></font></td><td align="center" bgcolor="#f46d43"><font size=1> <span style="background-color:white">0.00984</span></font></td><td>TIAN_TNF_SIGNALING_VIA_NFKB</td></tr>
<tr><td align="center" bgcolor="#a50026"><font size=1> <span style="background-color:white">0.00000</span></font></td><td align="center" bgcolor="#f46d43"><font size=1> <span style="background-color:white">0.00686</span></font></td><td>SEKI_INFLAMMATORY_RESPONSE_LPS_UP</td></tr>
<tr><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.03486</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.15521</span></font></td><td>ZUCCHI_METASTASIS_DN</td></tr>
<tr><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.08415</span></font></td><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.03725</span></font></td><td>GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP</td></tr>
<tr><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.01844</span></font></td><td align="center" bgcolor="#f46d43"><font size=1> <span style="background-color:white">0.00646</span></font></td><td>ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP</td></tr>
<tr><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.14826</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.09188</span></font></td><td>DIRMEIER_LMP1_RESPONSE_EARLY</td></tr>
<tr><td align="center" bgcolor="#f46d43"><font size=1> <span style="background-color:white">0.00810</span></font></td><td align="center" bgcolor="#d73027"><font size=1> <span style="background-color:white">0.00035</span></font></td><td>MAHADEVAN_RESPONSE_TO_MP470_UP</td></tr>
<tr><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.04170</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.08583</span></font></td><td>KRIGE_AMINO_ACID_DEPRIVATION</td></tr>
<tr><td align="center" bgcolor="#d73027"><font size=1> <span style="background-color:white">0.00069</span></font></td><td align="center" bgcolor="#fdae61"><font size=1> <span style="background-color:white">0.01841</span></font></td><td>PRAMOONJAGO_SOX4_TARGETS_UP</td></tr>
<tr><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.10685</span></font></td><td align="center" bgcolor="#fee08b"><font size=1> <span style="background-color:white">0.12704</span></font></td><td>HINATA_NFKB_TARGETS_FIBROBLAST_UP</td></tr>
</tbody>
</table>