BICLUSTER_ID : UPREG-74
PATHOGENS /8/ : pseudomonas aeruginosa,escherichia coli,streptococcus pneumoniae,bifidobacterium bifidum,lactobacillus acidophilus,yersinia enterocolitica,helicobacter pylori,shigella dysenteriae
TARGETS /2/ : NFKB1, PTGS2
Gene SetLeading Edge Genes
NETPATH IL 1 PATHWAY UPNFKB1, PTGS2, LIF, CXCL1, CXCL2
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
MISSIAGLIA REGULATED BY METHYLATION UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK BTRC NFKB2 PPP6C REL CUL1 IKBKE SAPS2 SAPS1 ANKRD28 RELA SKP1
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
MAHAJAN RESPONSE TO IL1A UP
BIOCARTA IL6 PATHWAY
NCI TNFPATHWAY
LINDSTEDT DENDRITIC CELL MATURATION B
CROONQUIST STROMAL STIMULATION UP
RASHI RESPONSE TO IONIZING RADIATION 2
NETPATH IL 1 PATHWAY
LINDSTEDT DENDRITIC CELL MATURATION A
ELVIDGE HYPOXIA UP
HORIUCHI WTAP TARGETS UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
ONDER CDH1 SIGNALING VIA CTNNB1
NETPATH IL 7 PATHWAY UP
MAHADEVAN RESPONSE TO MP470 DN
MITSIADES RESPONSE TO APLIDIN UP
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
NCI IL6 7PATHWAY
HARRIS HYPOXIA
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
HINATA NFKB TARGETS KERATINOCYTE UP
MARKEY RB1 ACUTE LOF UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
BASSO CD40 SIGNALING UP
AMIT SERUM RESPONSE 60 MCF10A
MARZEC IL2 SIGNALING UP
SOUCEK MYC TARGETS
NAGASHIMA NRG1 SIGNALING UP
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
ZERBINI RESPONSE TO SULINDAC UP
DIRMEIER LMP1 RESPONSE EARLY
FERRARI RESPONSE TO FENRETINIDE UP
BIOCARTA CD40 PATHWAY
BILD HRAS ONCOGENIC SIGNATURE
ZHOU INFLAMMATORY RESPONSE LIVE UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
LIANG SILENCED BY METHYLATION 2
BIOCARTA RANKL PATHWAY
NETPATH IL 6 PATHWAY UPGADD45B, CXCL1, MAP3K8
WINTER HYPOXIA METAGENE
SHAFFER IRF4 TARGETS IN PLASMA CELL VS MATURE B LYMPHOCYTE
PODAR RESPONSE TO ADAPHOSTIN UP
CHEN HOXA5 TARGETS 9HR UP
DAZARD UV RESPONSE CLUSTER G2
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
NETPATH IL 5 PATHWAY UP
FOSTER INFLAMMATORY RESPONSE LPS DN
SEKI INFLAMMATORY RESPONSE LPS UP
GRAHAM CML QUIESCENT VS CML DIVIDING UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
NETPATH TNF ALPHA PATHWAY UP
SANA TNF SIGNALING UP
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP
AMIT SERUM RESPONSE 120 MCF10A
AMIT EGF RESPONSE 240 HELA
NCI IL1PATHWAY
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
GEISS RESPONSE TO DSRNA UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
GERY CEBP TARGETS
ST TUMOR NECROSIS FACTOR PATHWAY
NCI NFKAPPABCANONICALPATHWAY
DASU IL6 SIGNALING UP
ELVIDGE HYPOXIA BY DMOG UP
TIAN TNF SIGNALING VIA NFKB
NETPATH IL 2 PATHWAY UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
ZUCCHI METASTASIS DN
NAGASHIMA EGF SIGNALING UP
PRAMOONJAGO SOX4 TARGETS UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bchelicobacter pylori kx1 mgeplactobacillus acidophilusbifidobacterium bifidumpseudomonas aeruginosa fdr440streptococcus pneumoniae g54escherichia colishigella dysenteriaeGeneSet Name
0.00001 0.00000 0.00114 0.00007 0.00000 0.02186 0.00000 0.00030NETPATH_IL_1_PATHWAY_UP
0.00007 0.10553 0.02479 0.01383 0.00001 0.00034 0.00000 0.18018CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.00107 0.00725 0.00001 0.00000 0.00000 0.00810 0.00000 0.00484MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.00000 0.00008 0.00598 0.01391 0.00010 0.01878 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.19049 0.05886 0.07030 0.15533 0.19871 0.14493 0.06283 0.17602CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_BTRC_NFKB2_PPP6C_REL_CUL1_IKBKE_SAPS2_SAPS1_ANKRD28_RELA_SKP1
0.00000 0.03509 0.00008 0.00214 0.01700 0.03257 0.00000 0.00252GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.00517 0.00430 0.00474 0.00044 0.08911 0.00000 0.00316MAHAJAN_RESPONSE_TO_IL1A_UP
0.17070 0.02454 0.13369 0.15558 0.09012 0.06093 0.02803 0.05423BIOCARTA_IL6_PATHWAY
0.19256 0.00024 0.00465 0.00099 0.03239 0.16078 0.00010 0.08513NCI_TNFPATHWAY
0.00004 0.00000 0.00000 0.00000 0.00000 0.00817 0.00000 0.00053LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00829 0.03674 0.04711 0.01386 0.00017 0.09861 0.00003 0.00808CROONQUIST_STROMAL_STIMULATION_UP
0.00001 0.00000 0.00034 0.00098 0.00000 0.00271 0.00000 0.00004RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00093 0.00053 0.10592 0.03028 0.00311 0.03624 0.00003 0.02164NETPATH_IL_1_PATHWAY
0.00000 0.00015 0.00000 0.00005 0.00003 0.16372 0.00000 0.00034LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00006 0.00083 0.10353 0.02232 0.16459 0.00034 0.01124 0.00124ELVIDGE_HYPOXIA_UP
0.00023 0.02539 0.00495 0.00296 0.00881 0.00695 0.00002 0.00236HORIUCHI_WTAP_TARGETS_UP
0.06007 0.00293 0.00648 0.01539 0.00064 0.03272 0.00026 0.00648IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.00018 0.00125 0.00081 0.00190 0.15015 0.02615 0.00000 0.00000AMIT_EGF_RESPONSE_40_HELA
0.01741 0.00188 0.05066 0.13470 0.00349 0.01436 0.00015 0.01233ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.00052 0.00294 0.06237 0.01764 0.00003 0.11486 0.00000 0.04120NETPATH_IL_7_PATHWAY_UP
0.00006 0.00340 0.00321 0.00016 0.02760 0.15502 0.00317 0.00000MAHADEVAN_RESPONSE_TO_MP470_DN
0.00513 0.00011 0.18043 0.13478 0.01817 0.00669 0.02480 0.00008MITSIADES_RESPONSE_TO_APLIDIN_UP
0.00000 0.00000 0.09352 0.07330 0.00052 0.09013 0.00000 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.08946 0.04616 0.12322 0.08284 0.14730 0.10802 0.00785 0.00624NCI_IL6_7PATHWAY
0.00004 0.00027 0.18721 0.05400 0.00003 0.10031 0.00034 0.00501HARRIS_HYPOXIA
0.00057 0.04563 0.09320 0.11437 0.01727 0.02323 0.00007 0.11015KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP
0.00012 0.00015 0.00593 0.04303 0.00448 0.01803 0.00002 0.00000DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.00000 0.00002 0.00000 0.00013 0.00000 0.00568 0.00000 0.00078HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00001 0.07713 0.00000 0.00000 0.01820 0.10730 0.00000 0.14227MARKEY_RB1_ACUTE_LOF_UP
0.00000 0.00005 0.00000 0.00000 0.00034 0.17463 0.00000 0.00096KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.00000 0.00077 0.00000 0.00006 0.00000 0.03498 0.00000 0.00004BASSO_CD40_SIGNALING_UP
0.00000 0.00013 0.17039 0.15969 0.01060 0.00321 0.00109 0.00000AMIT_SERUM_RESPONSE_60_MCF10A
0.00006 0.04862 0.15147 0.02397 0.01502 0.16651 0.00002 0.00321MARZEC_IL2_SIGNALING_UP
0.00001 0.00011 0.00010 0.00012 0.02994 0.08229 0.00037 0.02047SOUCEK_MYC_TARGETS
0.00000 0.00000 0.02256 0.05507 0.00002 0.00022 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.00008 0.01257 0.00089 0.00779 0.00021 0.00276 0.00000 0.08521NUYTTEN_EZH2_TARGETS_UP
0.00003 0.00000 0.00233 0.00215 0.00513 0.05455 0.00000 0.02611DUTTA_APOPTOSIS_VIA_NFKB
0.16203 0.00318 0.18728 0.11328 0.03840 0.09092 0.02814 0.07968ZERBINI_RESPONSE_TO_SULINDAC_UP
0.00000 0.00157 0.00007 0.00294 0.00002 0.08905 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00007 0.00008 0.15133 0.05329 0.00002 0.01205 0.00016 0.00712FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.09812 0.02889 0.03092 0.00439 0.00500 0.09309 0.00009 0.00438BIOCARTA_CD40_PATHWAY
0.00000 0.00029 0.00628 0.00118 0.00028 0.00093 0.00000 0.00000BILD_HRAS_ONCOGENIC_SIGNATURE
0.00000 0.00000 0.00000 0.00000 0.00010 0.11282 0.00000 0.00006ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.00000 0.00007 0.01803 0.00015 0.02769 0.01216 0.00155 0.00009GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP
0.00000 0.00003 0.09453 0.00402 0.00068 0.01466 0.00046 0.00113AMIT_EGF_RESPONSE_120_HELA
0.06147 0.00067 0.00259 0.00011 0.00085 0.03237 0.00003 0.00005DAUER_STAT3_TARGETS_UP
0.00007 0.00031 0.00000 0.00000 0.00005 0.01216 0.00000 0.00396LIANG_SILENCED_BY_METHYLATION_2
0.02104 0.02627 0.00384 0.00140 0.01277 0.11238 0.05932 0.15704BIOCARTA_RANKL_PATHWAY
0.00000 0.00236 0.00006 0.00007 0.03716 0.01842 0.00000 0.00000NETPATH_IL_6_PATHWAY_UP
0.00004 0.00017 0.11168 0.01386 0.00135 0.01549 0.02164 0.04655WINTER_HYPOXIA_METAGENE
0.00007 0.17649 0.12293 0.06171 0.09246 0.03041 0.05575 0.03786SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE
0.00000 0.00015 0.00831 0.00133 0.13382 0.00016 0.01026 0.00000PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.00001 0.00000 0.04051 0.07447 0.00550 0.00050 0.00050 0.00000CHEN_HOXA5_TARGETS_9HR_UP
0.00772 0.00079 0.06213 0.03296 0.00228 0.03619 0.00004 0.00032DAZARD_UV_RESPONSE_CLUSTER_G2
0.00000 0.00151 0.08350 0.06736 0.12253 0.01570 0.10160 0.00000GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.00001 0.00021 0.01533 0.11144 0.00726 0.07746 0.00001 0.00014NETPATH_IL_5_PATHWAY_UP
0.00000 0.00006 0.00000 0.00000 0.00037 0.01680 0.00000 0.00236FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.00000 0.00000 0.00000 0.00000 0.00000 0.02093 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00008 0.00937 0.00000 0.00000 0.00002 0.11160 0.00000 0.00003GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.00231 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00014 0.00002 0.00854 0.00015 0.03175 0.01005 0.08735 0.00146CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.01532 0.10562 0.09704 0.11156 0.00318 0.07319 0.00001 0.07626NETPATH_TNF_ALPHA_PATHWAY_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.15203 0.00000 0.00530SANA_TNF_SIGNALING_UP
0.00019 0.00000 0.03405 0.07657 0.06733 0.00031 0.01185 0.00000BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
0.00000 0.00289 0.01424 0.07807 0.02960 0.00320 0.00011 0.00021AMIT_SERUM_RESPONSE_120_MCF10A
0.00000 0.09400 0.14571 0.07547 0.01646 0.08012 0.00023 0.16919AMIT_EGF_RESPONSE_240_HELA
0.00841 0.06190 0.02751 0.00356 0.07208 0.18632 0.00686 0.02440NCI_IL1PATHWAY
0.00000 0.00215 0.11701 0.02116 0.00011 0.00067 0.00000 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00406 0.00438 0.02540 0.00136 0.02538 0.01104 0.00001 0.00000SESTO_RESPONSE_TO_UV_C3
0.00000 0.00063 0.03043 0.02011 0.00218 0.12533 0.00000 0.00095VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00001 0.01130 0.03083 0.02793 0.04896 0.09635 0.00002 0.00055BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.00000 0.00000 0.00027 0.00426 0.00007 0.03258 0.00000 0.01687GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.00000 0.03748 0.08234 0.02749 0.00000 0.00044 0.00000UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00013 0.00133 0.00427 0.00008 0.00131 0.12493 0.01389 0.00067GERY_CEBP_TARGETS
0.02172 0.00032 0.00006 0.00028 0.00001 0.10551 0.00026 0.01233ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.00132 0.00742 0.00905 0.01890 0.01645 0.05639 0.00009 0.03623NCI_NFKAPPABCANONICALPATHWAY
0.00001 0.07974 0.15237 0.05109 0.00711 0.09369 0.00015 0.00099DASU_IL6_SIGNALING_UP
0.00045 0.00023 0.12346 0.00784 0.15685 0.00018 0.01098 0.00078ELVIDGE_HYPOXIA_BY_DMOG_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.16057 0.00000 0.00005TIAN_TNF_SIGNALING_VIA_NFKB
0.00010 0.02575 0.01173 0.07512 0.00843 0.16635 0.00000 0.08636NETPATH_IL_2_PATHWAY_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.03864 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00000 0.00010 0.00475 0.01525 0.00011 0.01851 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00193 0.07700 0.04137 0.02142 0.00243 0.06587 0.00010 0.00154LEE_LIVER_CANCER_HEPATOBLAST
0.00010 0.00723 0.04132 0.03751 0.00002 0.01824 0.00000 0.00013ZUCCHI_METASTASIS_DN
0.00000 0.00000 0.05878 0.09324 0.00002 0.00045 0.00003 0.00000NAGASHIMA_EGF_SIGNALING_UP
0.00024 0.00000 0.00031 0.00000 0.00044 0.00000 0.00005 0.00000PRAMOONJAGO_SOX4_TARGETS_UP
0.00000 0.00002 0.00034 0.00605 0.06556 0.00267 0.02690 0.00000PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00001 0.00000 0.01167 0.05376 0.00000 0.02432 0.00000 0.00153HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00000 0.00002 0.00978 0.00467 0.00027 0.00090 0.00000 0.00000AMIT_EGF_RESPONSE_60_MCF10A