BICLUSTER_ID : UPREG-78
PATHOGENS /3/ : streptococcus pneumoniae,helicobacter pylori,shigella dysenteriae
TARGETS /7/ : NFKB1, PTGS2, ICAM1, CCL8, TNFRSF1B, IL1R1, PLAUR
Gene SetLeading Edge Genes
NETPATH TGFBETA RECEPTOR PATHWAY UPGADD45B, CYP24A1, DLX2, CDKN1A, HBEGF, FOSL1, NFKBIA, INHBA, IRAK2, BHLHB2, HES1, CASP4, IER3, DUSP5, LITAF, KLF10, CCL8, ACVR2A, DDIT4, TMEPAI, NFIL3, ETS2, VEGF, ATF3, IFRD1, PTGS2, SNF1LK, CDKN2B, IL1R1, PLAUR
NETPATH IL 1 PATHWAY UPRHOB, NFKBIE, HBEGF, FOSL1, NFKBIA, PTPN21, PRKCD, MMP10, INHBA, CXCL2, SOD2, PTX3, NFKB1, BIRC3, LIF, CXCL1, DUSP3, CCL8, JMJD3, PTGS2, ICAM1, ZFP36
NETPATH IL 1 PATHWAYNFKB1, SQSTM1, NFKBIA, IRAK2, IL1R1, MAPK8, MYD88
NETPATH TNF ALPHA PATHWAYNFKBIE, BIRC2, TNFRSF1B, NFKBIA, RIPK2, NFKBIZ, CFLAR, NFKB1, REL, BIRC3, TRAF3, DPF2, CYLD, BCL3, TBK1, TNFAIP3
NETPATH TNF ALPHA PATHWAY DOWNKLF6, CXCL1, KLF10, VEGF, NFKBIA, MAFF, GEM, TNFAIP3, PTGS2, CXCL2, FOSL2, BHLHB2, IER3
GENTILE UV RESPONSE CLUSTER D2
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
TURJANSKI MAPK7 TARGETS
MAHAJAN RESPONSE TO IL1A UP
VANHARANTA UTERINE FIBROID DN
CHUANG OXIDATIVE STRESS RESPONSE UP
SHEPARD CRUSH AND BURN MUTANT UP
VARELA ZMPSTE24 TARGETS UP
CHEN LVAD SUPPORT OF FAILING HEART UP
NCI TNFPATHWAY
LINDSTEDT DENDRITIC CELL MATURATION B
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
NCI GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT
ELVIDGE HYPOXIA UP
SESTO RESPONSE TO UV C0
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
AMIT EGF RESPONSE 40 HELA
KIM WT1 TARGETS 12HR DN
NETPATH IL 7 PATHWAY UP
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 5
BILD CTNNB1 ONCOGENIC SIGNATURE
JEON SMAD6 TARGETS UP
MITSIADES RESPONSE TO APLIDIN UP
HEDVAT ELF4 TARGETS UP
NCI IL6 7PATHWAY
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
MARTORIATI MDM4 TARGETS FETAL LIVER UP
TIEN INTESTINE PROBIOTICS 24HR DN
NUYTTEN NIPP1 TARGETS UP
HINATA NFKB TARGETS KERATINOCYTE UP
MARKEY RB1 ACUTE LOF UP
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY
DAZARD UV RESPONSE CLUSTER G3
NCI HIF1 TFPATHWAY
COULOUARN TEMPORAL TGFB1 SIGNATURE DN
XU HGF TARGETS INDUCED BY AKT1 48HR UP
OSADA ASCL1 TARGETS DN
AMIT SERUM RESPONSE 60 MCF10A
NUYTTEN EZH2 TARGETS UP
DUTTA APOPTOSIS VIA NFKB
COULOUARN TEMPORAL TGFB1 SIGNATURE UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS MAGENTA UP
HUANG FOXA2 TARGETS UP
TSAI RESPONSE TO IONIZING RADIATION
DIRMEIER LMP1 RESPONSE EARLY
ST GRANULE CELL SURVIVAL PATHWAY
CORUM RIBOSOME CYTOPLASMICRPS15A, RPL35, RPL4, RPS11, RPL23A, RPLP1, RPS17, RPS3A, RPS10, RPS21, RPS5, RPS16, RPS23, RPL11, RPS19, RPL30, RPL7A, RPL19, RPS4X, RPS2, RPL39, RPL5, RPL8, RPL15, RPL28, RPL37, RPL13A, RPS24, RPL7, RPS15, RPS3, RPL41
BIOCARTA CD40 PATHWAY
BIOCARTA ETS PATHWAY
ZHOU INFLAMMATORY RESPONSE LIVE UP
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP
AMIT EGF RESPONSE 120 HELA
DANG REGULATED BY MYC DN
BIOCARTA RANKL PATHWAY
NIELSEN MALIGNAT FIBROUS HISTIOCYTOMA UP
WINTER HYPOXIA METAGENE
GAJATE RESPONSE TO TRABECTEDIN UP
PODAR RESPONSE TO ADAPHOSTIN UP
SHAFFER IRF4 TARGETS IN PLASMA CELL VS MATURE B LYMPHOCYTE
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
FOSTER INFLAMMATORY RESPONSE LPS DN
NCI VIRAL MRNA TRANSLATION
TAVOR CEBPA TARGETS UP
REACTOME VIRAL MRNA TRANSLATION
CAFFAREL RESPONSE TO THC UP
KERLEY RESPONSE TO CISPLATIN UP
OSAWA TNF TARGETS
NCI EUKARYOTIC TRANSLATION TERMINATIONRPS15A, RPL35, RPL4, RPS11, RPL23A, RPLP1, RPS17, RPS3A, RPS10, RPS21, RPS5, RPS16, RPS23, RPL11, RPS19, RPL30, RPL7A, RPL19, RPS4X, RPS2, RPL39, RPL5, RPL8, RPL15, RPL28, RPL37, RPL13A, RPS24, RPL7, RPS15, RPS3, RPL41
NCI PEPTIDE CHAIN ELONGATIONRPS11, RPS17, RPS3A, RPS16, EEF1A1, RPS4X, RPS2, RPL39, RPL5, RPL37, RPL13A, RPS3, RPL41, RPL35, RPS15A, RPL4, RPLP1, RPL23A, RPS10, RPS5, RPS21, RPS23, RPS19, RPL11, RPL30, RPL7A, RPL19, RPL8, RPL28, RPL15, RPL7, RPS24, RPS15
SATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER
BIOCARTA CARDIACEGF PATHWAY
LAU APOPTOSIS CDKN2A UP
NETPATH TNF ALPHA PATHWAY UP
BROWNE HCMV INFECTION 14HR UP
NCI P38ALPHABETAPATHWAY
GESERICK TERT TARGETS DN
NGUYEN NOTCH1 TARGETS DN
AMIT SERUM RESPONSE 120 MCF10A
BROWNE HCMV INFECTION 2HR UP
BERENJENO TRANSFORMED BY RHOA UP
HALMOS CEBPA TARGETS DN
NCI IL1PATHWAY
BIOCARTA 41BB PATHWAY
SESTO RESPONSE TO UV C3
KEGG RIBOSOME
VERHAAK AML WITH NPM1 MUTATED UP
BROCKE APOPTOSIS REVERSED BY IL6
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS GREEN UP
GEISS RESPONSE TO DSRNA UP
GERY CEBP TARGETS
NCI P53DOWNSTREAMPATHWAY
GENTILE UV HIGH DOSE DN
ST TUMOR NECROSIS FACTOR PATHWAY
SENESE HDAC2 TARGETS UP
CHASSOT SKIN WOUND
TIAN TNF SIGNALING VIA NFKB
HUMMEL BURKITTS LYMPHOMA DN
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
AMIT DELAYED EARLY GENES
KRIGE AMINO ACID DEPRIVATION
AMIT EGF RESPONSE 60 MCF10A
HINATA NFKB TARGETS FIBROBLAST UP
NOJIMA SFRP2 TARGETS UP
CHARAFE BREAST CANCER LUMINAL VS BASAL DN
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN
CHEN HOXA5 TARGETS 6HR UP
MISSIAGLIA REGULATED BY METHYLATION UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
NCI TCRCALCIUMPATHWAY
NCI ATF2 PATHWAYATF3, DUSP5, DUSP8, DUSP1
CORUM TNF-ALPHA/NF-KAPPA B SIGNALING COMPLEX CHUK BTRC NFKB2 PPP6C REL CUL1 IKBKE SAPS2 SAPS1 ANKRD28 RELA SKP1
LEONARD HYPOXIA
NCI FORMATION OF A POOL OF FREE 40S SUBUNITS
RODRIGUES THYROID CARCINOMA DN
SESTO RESPONSE TO UV C1
JIANG HYPOXIA NORMAL
DAZARD RESPONSE TO UV SCC UP
CROONQUIST STROMAL STIMULATION UP
BERENJENO TRANSFORMED BY RHOA REVERSIBLY DN
HALMOS CEBPA TARGETS UP
BOYLAN MULTIPLE MYELOMA C DN
BLUM RESPONSE TO SALIRASIB UP
ZHANG RESPONSE TO CANTHARIDIN UP
SHAFFER IRF4 TARGETS IN MYELOMA VS MATURE B LYMPHOCYTE
KHETCHOUMIAN TRIM24 TARGETS UP
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP
BIOCARTA CDMAC PATHWAY
HORIUCHI WTAP TARGETS UP
ONDER CDH1 SIGNALING VIA CTNNB1
KEGG SMALL CELL LUNG CANCER
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
ZHONG RESPONSE TO AZACITIDINE AND TSA UP
MAHADEVAN RESPONSE TO MP470 DN
RUTELLA RESPONSE TO CSF2RB AND IL4 DN
DORN ADENOVIRUS INFECTION 12HR DN
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS CDC25 DN
HARRIS HYPOXIA
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP
CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA UP
NUNODA RESPONSE TO DASATINIB IMATINIB UP
REACTOME GTP HYDROLYSIS AND JOINING OF THE 60S RIBOSOMAL SUBUNIT
AMIT EGF RESPONSE 20 HELA
KAN RESPONSE TO ARSENIC TRIOXIDE
BASSO CD40 SIGNALING UP
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES
MARZEC IL2 SIGNALING UP
NAGASHIMA NRG1 SIGNALING UP
SOUCEK MYC TARGETS
ENK UV RESPONSE EPIDERMIS DN
BIOCARTA PPARA PATHWAY
CORUM UBIQUITIN E3 LIGASE NFKBIA BTRC CUL1 SKP1A
ZERBINI RESPONSE TO SULINDAC UP
BILBAN B CLL LPL DN
SCIAN INVERSED TARGETS OF TP53 AND TP73 DN
RASHI RESPONSE TO IONIZING RADIATION 1
NCI L13A MEDIATED TRANSLATIONAL SILENCING OF CERULOPLASMIN EXPRESSION
FERRARI RESPONSE TO FENRETINIDE UP
KEGG EPITHELIAL CELL SIGNALING IN HELICOBACTER PYLORI INFECTION
BILD HRAS ONCOGENIC SIGNATURE
LIANG SILENCED BY METHYLATION 2
DAUER STAT3 TARGETS UP
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN DN
SIG CD40PATHWAYMAP
NETPATH IL 6 PATHWAY UPGADD45B, CEBPD, CXCL1, CEBPB, HBEGF, MAFF, ZFP36, BHLHB2
NCI NF KB IS ACTIVATED AND SIGNALS SURVIVAL
MENSE HYPOXIA UPPTDSR, PFKFB3, CEBPD, CEBPB, VEGF, NFIL3, MAFF, ENO2, ATF3, STC2, ANKRD37, ADM, BHLHB2
REACTOME PEPTIDE CHAIN ELONGATION
AMIT EGF RESPONSE 60 HELA
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN
BERENJENO TRANSFORMED BY RHOA FOREVER DN
KANNAN TP53 TARGETS UP
CHEN HOXA5 TARGETS 9HR UP
DAZARD UV RESPONSE CLUSTER G2
SMITH TERT TARGETS UP
WANG CISPLATIN RESPONSE AND XPC DN
LEE SP4 THYMOCYTE
AMUNDSON RESPONSE TO ARSENITE
NETPATH IL 5 PATHWAY UP
AMIT SERUM RESPONSE 40 MCF10A
SEKI INFLAMMATORY RESPONSE LPS UP
NETPATH EGFR1 PATHWAY UP
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS
NCI CAP DEPENDENT TRANSLATION INITIATION
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
PARK TRETINOIN RESPONSE AND PML RARA FUSION
HELLER SILENCED BY METHYLATION DN
ENGELMANN CANCER PROGENITORS UP
BIERIE INFLAMMATORY RESPONSE TGFB1
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP
SANA TNF SIGNALING UP
SENESE HDAC1 AND HDAC2 TARGETS UP
WANG METHYLATED IN BREAST CANCER
SENESE HDAC1 TARGETS UP
REACTOME TOLL RECEPTOR CASCADES
INGA TP53 TARGETS
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
UDAYAKUMAR MED1 TARGETS DN
KIM WT1 TARGETS UP
SENESE HDAC3 TARGETS UP
REACTOME P75NTR SIGNALS VIA NFKB
ONDER CDH1 TARGETS 1 DN
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
XU HGF SIGNALING NOT VIA AKT1 6HR
BIOCARTA KERATINOCYTE PATHWAY
NCI SMAD2 3NUCLEARPATHWAYSKIL, ATF3, NCOR1, SAP30, CDKN1A, CEBPB, CDKN2B
NCI NFKAPPABCANONICALPATHWAY
HESS TARGETS OF HOXA9 AND MEIS1 DN
DASU IL6 SIGNALING UP
ELVIDGE HYPOXIA BY DMOG UP
NETPATH IL 2 PATHWAY UP
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
REACTOME FORMATION OF A POOL OF FREE 40S SUBUNITS
CORUM 60S RIBOSOMAL SUBUNIT CYTOPLASMIC
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
ZUCCHI METASTASIS DN
BERENJENO ROCK SIGNALING NOT VIA RHOA DN
BIOCARTA ARENRF2 PATHWAY
RUTELLA RESPONSE TO HGF UP
DAZARD RESPONSE TO UV SCC DN
PRAMOONJAGO SOX4 TARGETS UP
KIM WT1 TARGETS 8HR UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 1
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
streptococcus pneumoniae g54helicobacter pylori kx2 mgepshigella dysenteriaeGeneSet Name
0.03675 0.07419 0.09633NETPATH_TGFBETA_RECEPTOR_PATHWAY_UP
0.02186 0.00000 0.00030NETPATH_IL_1_PATHWAY_UP
0.03624 0.00458 0.02164NETPATH_IL_1_PATHWAY
0.02401 0.04027 0.03020NETPATH_TNF_ALPHA_PATHWAY
0.00809 0.00340 0.00000NETPATH_TNF_ALPHA_PATHWAY_DOWN
0.02049 0.01625 0.01824GENTILE_UV_RESPONSE_CLUSTER_D2
0.03257 0.00541 0.00252GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.11975 0.13640 0.07009TURJANSKI_MAPK7_TARGETS
0.08911 0.00001 0.00316MAHAJAN_RESPONSE_TO_IL1A_UP
0.00677 0.00272 0.08927VANHARANTA_UTERINE_FIBROID_DN
0.12323 0.00171 0.07731CHUANG_OXIDATIVE_STRESS_RESPONSE_UP
0.17430 0.07454 0.00030SHEPARD_CRUSH_AND_BURN_MUTANT_UP
0.01900 0.00016 0.00166VARELA_ZMPSTE24_TARGETS_UP
0.01145 0.00040 0.00017CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP
0.16078 0.00279 0.08513NCI_TNFPATHWAY
0.00817 0.00000 0.00053LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00271 0.00000 0.00004RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.16372 0.00000 0.00034LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.08582 0.00000 0.00308NCI_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT
0.00034 0.00095 0.00124ELVIDGE_HYPOXIA_UP
0.00808 0.13763 0.02792SESTO_RESPONSE_TO_UV_C0
0.03272 0.01339 0.00648IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.02615 0.00053 0.00000AMIT_EGF_RESPONSE_40_HELA
0.06314 0.11712 0.09521KIM_WT1_TARGETS_12HR_DN
0.11486 0.00019 0.04120NETPATH_IL_7_PATHWAY_UP
0.03309 0.00313 0.02126YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5
0.01439 0.08142 0.15744BILD_CTNNB1_ONCOGENIC_SIGNATURE
0.02288 0.00000 0.02542JEON_SMAD6_TARGETS_UP
0.00669 0.00011 0.00008MITSIADES_RESPONSE_TO_APLIDIN_UP
0.16616 0.13156 0.14659HEDVAT_ELF4_TARGETS_UP
0.10802 0.09551 0.00624NCI_IL6_7PATHWAY
0.09013 0.00010 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.07515 0.06503 0.02731MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP
0.00936 0.15001 0.06883TIEN_INTESTINE_PROBIOTICS_24HR_DN
0.00315 0.14612 0.09420NUYTTEN_NIPP1_TARGETS_UP
0.00568 0.00000 0.00078HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.10730 0.09595 0.14227MARKEY_RB1_ACUTE_LOF_UP
0.17463 0.00019 0.00096KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
0.03860 0.01539 0.00253DAZARD_UV_RESPONSE_CLUSTER_G3
0.10049 0.00048 0.08693NCI_HIF1_TFPATHWAY
0.12491 0.12401 0.09634COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN
0.18837 0.19637 0.03970XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP
0.03295 0.14030 0.01483OSADA_ASCL1_TARGETS_DN
0.00321 0.00000 0.00000AMIT_SERUM_RESPONSE_60_MCF10A
0.00276 0.02487 0.08521NUYTTEN_EZH2_TARGETS_UP
0.05455 0.00000 0.02611DUTTA_APOPTOSIS_VIA_NFKB
0.00641 0.02721 0.14473COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP
0.00558 0.04284 0.00000GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP
0.08226 0.01079 0.05174HUANG_FOXA2_TARGETS_UP
0.03105 0.00328 0.00016TSAI_RESPONSE_TO_IONIZING_RADIATION
0.08905 0.00124 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.09235 0.11236 0.00091ST_GRANULE_CELL_SURVIVAL_PATHWAY
0.04216 0.00000 0.00348CORUM_RIBOSOME_CYTOPLASMIC
0.09309 0.00076 0.00438BIOCARTA_CD40_PATHWAY
0.12208 0.05224 0.04136BIOCARTA_ETS_PATHWAY
0.11282 0.00000 0.00006ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.01828 0.13593 0.02436RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP
0.01216 0.00044 0.00009GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP
0.01466 0.00007 0.00113AMIT_EGF_RESPONSE_120_HELA
0.07999 0.13619 0.18421DANG_REGULATED_BY_MYC_DN
0.11238 0.04291 0.15704BIOCARTA_RANKL_PATHWAY
0.13119 0.00622 0.13279NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_UP
0.01549 0.00315 0.04655WINTER_HYPOXIA_METAGENE
0.00696 0.10731 0.10594GAJATE_RESPONSE_TO_TRABECTEDIN_UP
0.00016 0.00000 0.00000PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.03041 0.07351 0.03786SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE
0.01570 0.00092 0.00000GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.01680 0.00146 0.00236FOSTER_INFLAMMATORY_RESPONSE_LPS_DN
0.06641 0.00000 0.00597NCI_VIRAL_MRNA_TRANSLATION
0.04868 0.04908 0.00349TAVOR_CEBPA_TARGETS_UP
0.06578 0.00000 0.00478REACTOME_VIRAL_MRNA_TRANSLATION
0.05585 0.06974 0.18953CAFFAREL_RESPONSE_TO_THC_UP
0.01965 0.18636 0.16070KERLEY_RESPONSE_TO_CISPLATIN_UP
0.00719 0.01263 0.07902OSAWA_TNF_TARGETS
0.04420 0.00000 0.00438NCI_EUKARYOTIC_TRANSLATION_TERMINATION
0.04545 0.00000 0.00390NCI_PEPTIDE_CHAIN_ELONGATION
0.02405 0.15948 0.00666SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER
0.13908 0.13611 0.03767BIOCARTA_CARDIACEGF_PATHWAY
0.01015 0.01625 0.02539LAU_APOPTOSIS_CDKN2A_UP
0.07319 0.16490 0.07626NETPATH_TNF_ALPHA_PATHWAY_UP
0.05440 0.16828 0.09043BROWNE_HCMV_INFECTION_14HR_UP
0.07814 0.10991 0.10913NCI_P38ALPHABETAPATHWAY
0.00310 0.00002 0.00000GESERICK_TERT_TARGETS_DN
0.01647 0.06874 0.02680NGUYEN_NOTCH1_TARGETS_DN
0.00320 0.00109 0.00021AMIT_SERUM_RESPONSE_120_MCF10A
0.04469 0.00890 0.00008BROWNE_HCMV_INFECTION_2HR_UP
0.09492 0.15052 0.12456BERENJENO_TRANSFORMED_BY_RHOA_UP
0.15673 0.06099 0.00654HALMOS_CEBPA_TARGETS_DN
0.18632 0.02503 0.02440NCI_IL1PATHWAY
0.19974 0.00231 0.06816BIOCARTA_41BB_PATHWAY
0.01104 0.00018 0.00000SESTO_RESPONSE_TO_UV_C3
0.05727 0.00000 0.00526KEGG_RIBOSOME
0.12533 0.00145 0.00095VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.09635 0.00158 0.00055BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.12015 0.04789 0.07453GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP
0.03258 0.00000 0.01687GEISS_RESPONSE_TO_DSRNA_UP
0.12493 0.00038 0.00067GERY_CEBP_TARGETS
0.06541 0.11095 0.01375NCI_P53DOWNSTREAMPATHWAY
0.00382 0.01489 0.00820GENTILE_UV_HIGH_DOSE_DN
0.10551 0.00008 0.01233ST_TUMOR_NECROSIS_FACTOR_PATHWAY
0.12202 0.04258 0.04658SENESE_HDAC2_TARGETS_UP
0.03610 0.00239 0.00141CHASSOT_SKIN_WOUND
0.16057 0.00000 0.00005TIAN_TNF_SIGNALING_VIA_NFKB
0.05491 0.07423 0.03331HUMMEL_BURKITTS_LYMPHOMA_DN
0.06587 0.10358 0.00154LEE_LIVER_CANCER_HEPATOBLAST
0.00045 0.00000 0.00000NAGASHIMA_EGF_SIGNALING_UP
0.01300 0.00009 0.00000AMIT_DELAYED_EARLY_GENES
0.04467 0.00000 0.03473KRIGE_AMINO_ACID_DEPRIVATION
0.00090 0.00000 0.00000AMIT_EGF_RESPONSE_60_MCF10A
0.02432 0.00009 0.00153HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.17017 0.00000 0.00035NOJIMA_SFRP2_TARGETS_UP
0.00034 0.05697 0.18018CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN
0.00020 0.14114 0.08446NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN
0.01846 0.00788 0.00221CHEN_HOXA5_TARGETS_6HR_UP
0.00810 0.00396 0.00484MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.01189 0.06739 0.05182SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.01878 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.15695 0.15099 0.03669NCI_TCRCALCIUMPATHWAY
0.03036 0.00272 0.00000NCI_ATF2_PATHWAY
0.14493 0.00200 0.17602CORUM_TNF-ALPHA/NF-KAPPA_B_SIGNALING_COMPLEX_CHUK_BTRC_NFKB2_PPP6C_REL_CUL1_IKBKE_SAPS2_SAPS1_ANKRD28_RELA_SKP1
0.00548 0.00000 0.01701LEONARD_HYPOXIA
0.05058 0.00000 0.00627NCI_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS
0.02448 0.00189 0.15261RODRIGUES_THYROID_CARCINOMA_DN
0.00828 0.00303 0.19068SESTO_RESPONSE_TO_UV_C1
0.00556 0.19586 0.14726JIANG_HYPOXIA_NORMAL
0.01405 0.18778 0.10446DAZARD_RESPONSE_TO_UV_SCC_UP
0.09861 0.05041 0.00808CROONQUIST_STROMAL_STIMULATION_UP
0.11462 0.04846 0.02359BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN
0.02527 0.03870 0.00005HALMOS_CEBPA_TARGETS_UP
0.10863 0.12934 0.02535BOYLAN_MULTIPLE_MYELOMA_C_DN
0.00392 0.00019 0.02010BLUM_RESPONSE_TO_SALIRASIB_UP
0.03275 0.00028 0.04574ZHANG_RESPONSE_TO_CANTHARIDIN_UP
0.02411 0.15192 0.14059SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE
0.02156 0.12799 0.00741KHETCHOUMIAN_TRIM24_TARGETS_UP
0.00388 0.10597 0.17314KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP
0.16806 0.12419 0.00253BIOCARTA_CDMAC_PATHWAY
0.00695 0.01380 0.00236HORIUCHI_WTAP_TARGETS_UP
0.01436 0.00028 0.01233ONDER_CDH1_SIGNALING_VIA_CTNNB1
0.07564 0.11981 0.11081KEGG_SMALL_CELL_LUNG_CANCER
0.04993 0.01011 0.15816GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.09090 0.09966 0.05696ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP
0.15502 0.00005 0.00000MAHADEVAN_RESPONSE_TO_MP470_DN
0.03089 0.16288 0.01423RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN
0.10988 0.01580 0.00032DORN_ADENOVIRUS_INFECTION_12HR_DN
0.02167 0.10649 0.00072CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN
0.10031 0.00009 0.00501HARRIS_HYPOXIA
0.02323 0.11555 0.11015KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP
0.01803 0.00012 0.00000DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP
0.04079 0.01398 0.00304CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP
0.11072 0.05677 0.04064NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP
0.08161 0.00000 0.00284REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT
0.04591 0.00435 0.00013AMIT_EGF_RESPONSE_20_HELA
0.04440 0.00248 0.02489KAN_RESPONSE_TO_ARSENIC_TRIOXIDE
0.03498 0.01278 0.00004BASSO_CD40_SIGNALING_UP
0.17791 0.07909 0.07100REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES
0.16651 0.01784 0.00321MARZEC_IL2_SIGNALING_UP
0.00022 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.08229 0.00002 0.02047SOUCEK_MYC_TARGETS
0.00387 0.13096 0.00875ENK_UV_RESPONSE_EPIDERMIS_DN
0.18979 0.15599 0.00093BIOCARTA_PPARA_PATHWAY
0.13864 0.13461 0.12165CORUM_UBIQUITIN_E3_LIGASE_NFKBIA_BTRC_CUL1_SKP1A
0.09092 0.00100 0.07968ZERBINI_RESPONSE_TO_SULINDAC_UP
0.05066 0.12382 0.00008BILBAN_B_CLL_LPL_DN
0.08263 0.01597 0.02516SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN
0.02099 0.16167 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_1
0.09240 0.00000 0.00439NCI_L13A_MEDIATED_TRANSLATIONAL_SILENCING_OF_CERULOPLASMIN_EXPRESSION
0.01205 0.00002 0.00712FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.07363 0.00335 0.11725KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION
0.00093 0.00132 0.00000BILD_HRAS_ONCOGENIC_SIGNATURE
0.01216 0.00002 0.00396LIANG_SILENCED_BY_METHYLATION_2
0.03237 0.00008 0.00005DAUER_STAT3_TARGETS_UP
0.02602 0.01763 0.06512ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN
0.02635 0.00807 0.17750SIG_CD40PATHWAYMAP
0.01842 0.01969 0.00000NETPATH_IL_6_PATHWAY_UP
0.17477 0.00115 0.04605NCI_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL
0.00004 0.00036 0.02114MENSE_HYPOXIA_UP
0.04336 0.00000 0.00324REACTOME_PEPTIDE_CHAIN_ELONGATION
0.02905 0.00000 0.00007AMIT_EGF_RESPONSE_60_HELA
0.09462 0.00073 0.00827ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN
0.02282 0.02345 0.00170BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.00648 0.01451 0.02322KANNAN_TP53_TARGETS_UP
0.00050 0.00000 0.00000CHEN_HOXA5_TARGETS_9HR_UP
0.03619 0.00000 0.00032DAZARD_UV_RESPONSE_CLUSTER_G2
0.00324 0.00076 0.04166SMITH_TERT_TARGETS_UP
0.01848 0.19317 0.13229WANG_CISPLATIN_RESPONSE_AND_XPC_DN
0.15653 0.13635 0.03500LEE_SP4_THYMOCYTE
0.00551 0.00019 0.17228AMUNDSON_RESPONSE_TO_ARSENITE
0.07746 0.00002 0.00014NETPATH_IL_5_PATHWAY_UP
0.00737 0.00219 0.00000AMIT_SERUM_RESPONSE_40_MCF10A
0.02093 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.11210 0.07001 0.00148NETPATH_EGFR1_PATHWAY_UP
0.11162 0.00000 0.04000REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS
0.09055 0.00000 0.00337NCI_CAP_DEPENDENT_TRANSLATION_INITIATION
0.11160 0.00677 0.00003GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.01005 0.00000 0.00146CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.00231 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.15242 0.03379 0.08035PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION
0.18318 0.00001 0.07958HELLER_SILENCED_BY_METHYLATION_DN
0.00380 0.05585 0.12755ENGELMANN_CANCER_PROGENITORS_UP
0.05057 0.00543 0.05553BIERIE_INFLAMMATORY_RESPONSE_TGFB1
0.00031 0.00002 0.00000BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP
0.15203 0.00000 0.00530SANA_TNF_SIGNALING_UP
0.15156 0.00621 0.00255SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.02474 0.01533 0.10922WANG_METHYLATED_IN_BREAST_CANCER
0.05349 0.02102 0.02245SENESE_HDAC1_TARGETS_UP
0.15988 0.12440 0.15216REACTOME_TOLL_RECEPTOR_CASCADES
0.13640 0.02719 0.10402INGA_TP53_TARGETS
0.00067 0.00008 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00081 0.00052 0.01643UDAYAKUMAR_MED1_TARGETS_DN
0.00273 0.00000 0.00000KIM_WT1_TARGETS_UP
0.03264 0.04896 0.02950SENESE_HDAC3_TARGETS_UP
0.13024 0.00146 0.01379REACTOME_P75NTR_SIGNALS_VIA_NFKB
0.07758 0.00512 0.09552ONDER_CDH1_TARGETS_1_DN
0.00000 0.00000 0.00000UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.06148 0.00823 0.00031XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR
0.06149 0.04845 0.00147BIOCARTA_KERATINOCYTE_PATHWAY
0.02286 0.05043 0.09717NCI_SMAD2_3NUCLEARPATHWAY
0.05639 0.01694 0.03623NCI_NFKAPPABCANONICALPATHWAY
0.13868 0.11528 0.00054HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.09369 0.10056 0.00099DASU_IL6_SIGNALING_UP
0.00018 0.00024 0.00078ELVIDGE_HYPOXIA_BY_DMOG_UP
0.16635 0.04909 0.08636NETPATH_IL_2_PATHWAY_UP
0.03864 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.04813 0.00000 0.00577REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS
0.08629 0.00000 0.03386CORUM_60S_RIBOSOMAL_SUBUNIT_CYTOPLASMIC
0.01851 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.01824 0.00076 0.00013ZUCCHI_METASTASIS_DN
0.10586 0.08273 0.01384BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN
0.02407 0.11600 0.00149BIOCARTA_ARENRF2_PATHWAY
0.00850 0.10020 0.10389RUTELLA_RESPONSE_TO_HGF_UP
0.00931 0.00343 0.03700DAZARD_RESPONSE_TO_UV_SCC_DN
0.00000 0.00000 0.00000PRAMOONJAGO_SOX4_TARGETS_UP
0.01014 0.00689 0.00229KIM_WT1_TARGETS_8HR_UP
0.00267 0.00000 0.00000PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.07009 0.00291 0.03633YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1