BICLUSTER_ID : UPREG-88
PATHOGENS /4/ : escherichia coli,yersinia enterocolitica,porphyromonas gingivalis,ehrlichia chaffeensis
TARGETS /1/ : CCL2
Gene SetLeading Edge Genes
NETPATH IL 9 PATHWAY UPSOCS3, CCL2
NETPATH IL 4 PATHWAY DOWNGADD45B, CCL2
NETPATH IL 3 PATHWAY UPSOCS3, CCL2
NETPATH IL 4 PATHWAY UPSOCS3, CCL2, IL10
NCI IL23PATHWAYSOCS3, CXCL1, CCL2, CXCL9
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
NCI ATF2 PATHWAY
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
LINDGREN BLADDER CANCER CLUSTER 2B
KEGG GRAFT VERSUS HOST DISEASE
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS
LINDSTEDT DENDRITIC CELL MATURATION B
HALMOS CEBPA TARGETS UP
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
WALLACE PROSTATE CANCER RACE UP
AMIT EGF RESPONSE 40 HELA
GUTIERREZ WALDENSTROEMS MACROGLOBULINEMIA 1 DN
NETPATH IL 7 PATHWAY UPCXCL1
BUDHU LIVER CANCER METASTASIS DN
KEGG JAK STAT SIGNALING PATHWAY
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP
HARRIS HYPOXIA
HINATA NFKB TARGETS KERATINOCYTE UP
BIOCARTA CYTOKINE PATHWAY
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D DN
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR UP
OSADA ASCL1 TARGETS DN
SOUCEK MYC TARGETS
NAGASHIMA NRG1 SIGNALING UP
BIOCARTA DC PATHWAY
BOYLAN MULTIPLE MYELOMA C D DN
ZERBINI RESPONSE TO SULINDAC UP
BILBAN B CLL LPL DN
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
SMID BREAST CANCER NORMAL LIKE UP
ZHOU INFLAMMATORY RESPONSE LIVE UP
ONDER CDH1 TARGETS 3 DN
DAUER STAT3 TARGETS UP
NETPATH IL 6 PATHWAY UPSOCS3, GADD45B, CXCL1
MCLACHLAN DENTAL CARIES UP
WU HBX TARGETS 1 UP
BERENJENO TRANSFORMED BY RHOA FOREVER DN
DAZARD UV RESPONSE CLUSTER G2
TAVOR CEBPA TARGETS UP
MCLACHLAN DENTAL CARIES DN
SEKI INFLAMMATORY RESPONSE LPS UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
NCI AMB2 NEUTROPHILS PATHWAY
SMID BREAST CANCER LUMINAL B DN
GESERICK TERT TARGETS DN
NCI IL27PATHWAY
AMIT SERUM RESPONSE 120 MCF10A
ONDER CDH1 TARGETS 2 DN
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
KEGG HEMATOPOIETIC CELL LINEAGE
BROCKE APOPTOSIS REVERSED BY IL6
REACTOME G ALPHA I SIGNALLING EVENTS
GEISS RESPONSE TO DSRNA UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
GRAHAM CML DIVIDING VS NORMAL QUIESCENT DN
TIAN TNF SIGNALING VIA NFKB
IIZUKA RECURRENT LIVER CANCER
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
GOUYER TATI TARGETS UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
LEE LIVER CANCER HEPATOBLAST
NAGASHIMA EGF SIGNALING UP
LU IL4 SIGNALING
WATTEL AUTONOMOUS THYROID ADENOMA DN
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN
AMIT EGF RESPONSE 60 MCF10A
HINATA NFKB TARGETS FIBROBLAST UP
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
yersinia enterocolitica wap bl6yersinia enterocolitica wap bcyersinia enterocolitica p60 bl6yersinia enterocolitica p60 bcporphyromonas gingivalisehrlichia chaffeensis libertyehrlichia chaffeensis arkansaehrlichia chaffeensis wakullaescherichia coliGeneSet Name
0.00016 0.00001 0.00016 0.00009 0.01126 0.00207 0.00097 0.00000 0.00028NETPATH_IL_9_PATHWAY_UP
0.00145 0.00024 0.00146 0.00040 0.00395 0.00340 0.00001 0.00000 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.00000 0.00000 0.00000 0.00000 0.12641 0.00030 0.00000 0.00000 0.00000NETPATH_IL_3_PATHWAY_UP
0.00016 0.00017 0.00010 0.00000 0.03326 0.02314 0.00011 0.00000 0.00129NETPATH_IL_4_PATHWAY_UP
0.00000 0.00001 0.00000 0.00000 0.00584 0.00440 0.00000 0.00020 0.00000NCI_IL23PATHWAY
0.00000 0.00001 0.00000 0.00000 0.00839 0.00077 0.00000 0.00000 0.00000KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00000 0.00000 0.00000 0.00000 0.03623 0.09755 0.00488 0.00301 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.19595 0.00040 0.05363 0.00891 0.00897 0.18902 0.02314 0.00196 0.01874NCI_ATF2_PATHWAY
0.00000 0.00000 0.00021 0.00000 0.02363 0.01105 0.00021 0.00547 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.02833 0.00193 0.01562 0.00358 0.12757 0.00007 0.00000 0.00000 0.01415LINDGREN_BLADDER_CANCER_CLUSTER_2B
0.00424 0.00024 0.00069 0.00055 0.15597 0.00002 0.00000 0.00000 0.00002KEGG_GRAFT_VERSUS_HOST_DISEASE
0.00026 0.05073 0.00794 0.00417 0.00871 0.10026 0.00034 0.00004 0.00121REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS
0.04571 0.00004 0.04591 0.00237 0.02335 0.02223 0.00007 0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_B
0.00185 0.00154 0.00022 0.00037 0.03979 0.03077 0.03101 0.00175 0.00001HALMOS_CEBPA_TARGETS_UP
0.00427 0.00001 0.00297 0.00008 0.02386 0.09956 0.00307 0.00001 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00011 0.00000 0.00029 0.00000 0.00457 0.00000 0.00000 0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00001 0.00000 0.00029 0.00000 0.19031 0.00000 0.00000 0.00000 0.00004WALLACE_PROSTATE_CANCER_RACE_UP
0.01474 0.00018 0.00021 0.00031 0.00131 0.15480 0.03874 0.00042 0.00000AMIT_EGF_RESPONSE_40_HELA
0.01516 0.01934 0.03385 0.02619 0.04210 0.03335 0.15904 0.02715 0.01179GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN
0.00623 0.00052 0.00709 0.00028 0.01741 0.00005 0.00034 0.00004 0.00000NETPATH_IL_7_PATHWAY_UP
0.00653 0.00899 0.02833 0.02068 0.10290 0.05362 0.01307 0.01959 0.00126BUDHU_LIVER_CANCER_METASTASIS_DN
0.00005 0.00277 0.00111 0.00015 0.12580 0.18395 0.01019 0.00097 0.00009KEGG_JAK_STAT_SIGNALING_PATHWAY
0.01109 0.00012 0.00708 0.00004 0.12409 0.06656 0.00081 0.00001 0.00220TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP
0.00250 0.00004 0.00029 0.00029 0.08079 0.03906 0.00160 0.00025 0.00034HARRIS_HYPOXIA
0.00000 0.00000 0.00000 0.00000 0.00133 0.00058 0.00055 0.00001 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.00000 0.00004 0.00009 0.00047 0.00278 0.02223 0.04697 0.04300 0.00002BIOCARTA_CYTOKINE_PATHWAY
0.00195 0.00004 0.00040 0.00020 0.03845 0.00734 0.00053 0.00000 0.10451TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN
0.00426 0.06817 0.03296 0.00854 0.15449 0.00719 0.00044 0.00344 0.14890TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP
0.08327 0.08630 0.08169 0.06140 0.00441 0.00584 0.00001 0.00002 0.00002OSADA_ASCL1_TARGETS_DN
0.00000 0.00001 0.00018 0.00008 0.03916 0.00038 0.00003 0.00027 0.00037SOUCEK_MYC_TARGETS
0.00002 0.00000 0.00000 0.00000 0.00124 0.00351 0.00648 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.00606 0.07276 0.04231 0.04900 0.00361 0.00817 0.00147 0.01675 0.00672BIOCARTA_DC_PATHWAY
0.00251 0.00901 0.01871 0.02450 0.19005 0.00000 0.00000 0.00000 0.05549BOYLAN_MULTIPLE_MYELOMA_C_D_DN
0.13677 0.16203 0.05840 0.12784 0.02341 0.13115 0.07345 0.11589 0.02814ZERBINI_RESPONSE_TO_SULINDAC_UP
0.02307 0.00001 0.00270 0.00101 0.09608 0.00006 0.00034 0.00005 0.14289BILBAN_B_CLL_LPL_DN
0.00000 0.00000 0.00018 0.00000 0.00483 0.00342 0.00000 0.00000 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00025 0.00006 0.00018 0.00000 0.18333 0.00131 0.00029 0.00001 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.00889 0.11477 0.01677 0.09807 0.12023 0.00000 0.00000 0.00000 0.13855SMID_BREAST_CANCER_NORMAL_LIKE_UP
0.00000 0.00000 0.00000 0.00000 0.12784 0.05362 0.01092 0.00039 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.00150 0.01083 0.00026 0.00099 0.00916 0.16184 0.02809 0.00507 0.00000ONDER_CDH1_TARGETS_3_DN
0.05660 0.06147 0.06189 0.02597 0.00811 0.06350 0.01097 0.00307 0.00003DAUER_STAT3_TARGETS_UP
0.00000 0.00000 0.00000 0.00000 0.09273 0.00150 0.00003 0.00000 0.00000NETPATH_IL_6_PATHWAY_UP
0.00049 0.00000 0.00050 0.00008 0.08054 0.00000 0.00000 0.00000 0.00000MCLACHLAN_DENTAL_CARIES_UP
0.00703 0.00334 0.00917 0.00739 0.11831 0.01391 0.02293 0.11208 0.00099WU_HBX_TARGETS_1_UP
0.19546 0.00000 0.00332 0.00060 0.06745 0.12473 0.00705 0.00358 0.00016BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.11521 0.00772 0.01250 0.01385 0.01540 0.05324 0.03944 0.00111 0.00004DAZARD_UV_RESPONSE_CLUSTER_G2
0.15470 0.01106 0.06979 0.02930 0.02033 0.04493 0.00572 0.00085 0.00020TAVOR_CEBPA_TARGETS_UP
0.00078 0.00001 0.00065 0.00014 0.08235 0.00000 0.00000 0.00000 0.00002MCLACHLAN_DENTAL_CARIES_DN
0.00000 0.00000 0.00000 0.00000 0.00125 0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.00000 0.00000 0.00000 0.00000 0.00127 0.00059 0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.03531 0.04505 0.17478 0.00186 0.08425 0.01327 0.00021 0.00002 0.00044NCI_AMB2_NEUTROPHILS_PATHWAY
0.00087 0.00824 0.00018 0.00148 0.04544 0.00253 0.00000 0.00000 0.00006SMID_BREAST_CANCER_LUMINAL_B_DN
0.00141 0.00000 0.00000 0.00004 0.03305 0.00164 0.00047 0.00032 0.00083GESERICK_TERT_TARGETS_DN
0.02027 0.00720 0.02901 0.00318 0.07257 0.03237 0.00000 0.00004 0.00000NCI_IL27PATHWAY
0.00013 0.00000 0.00007 0.00000 0.00000 0.00533 0.04018 0.00009 0.00011AMIT_SERUM_RESPONSE_120_MCF10A
0.00065 0.00111 0.00022 0.00011 0.07092 0.03586 0.00757 0.00036 0.00002ONDER_CDH1_TARGETS_2_DN
0.00080 0.00000 0.00030 0.00006 0.05737 0.02652 0.00262 0.00004 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00757 0.00406 0.00078 0.00270 0.00266 0.11456 0.17152 0.01412 0.00001SESTO_RESPONSE_TO_UV_C3
0.00000 0.00344 0.00043 0.00057 0.02431 0.00000 0.00000 0.00000 0.00021KEGG_HEMATOPOIETIC_CELL_LINEAGE
0.01123 0.00001 0.04624 0.00068 0.14398 0.00011 0.00000 0.00000 0.00002BROCKE_APOPTOSIS_REVERSED_BY_IL6
0.02054 0.10388 0.01582 0.01232 0.15518 0.00648 0.00009 0.00052 0.01653REACTOME_G_ALPHA_I_SIGNALLING_EVENTS
0.00179 0.00000 0.00109 0.00000 0.12681 0.01274 0.00175 0.00022 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.00000 0.00000 0.00000 0.00000 0.10221 0.02814 0.00336 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00514 0.00011 0.00272 0.00007 0.01492 0.00118 0.00015 0.00030 0.00000GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN
0.00000 0.00000 0.00016 0.00000 0.00000 0.02222 0.00003 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.12116 0.01070 0.09789 0.03196 0.03888 0.17711 0.00929 0.01342 0.02641IIZUKA_RECURRENT_LIVER_CANCER
0.00024 0.00000 0.00037 0.00000 0.09753 0.00033 0.00001 0.00009 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.01812 0.00294 0.08058 0.01389 0.08157 0.06698 0.05925 0.06016 0.03224GOUYER_TATI_TARGETS_UP
0.00000 0.00000 0.00000 0.00000 0.03617 0.10357 0.00511 0.00265 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00139 0.00193 0.00058 0.00168 0.11913 0.02333 0.00021 0.00011 0.00010LEE_LIVER_CANCER_HEPATOBLAST
0.00000 0.00000 0.00000 0.00000 0.00025 0.01422 0.00040 0.00000 0.00003NAGASHIMA_EGF_SIGNALING_UP
0.00017 0.00006 0.00176 0.00004 0.06609 0.00508 0.00276 0.00009 0.00649LU_IL4_SIGNALING
0.01754 0.02654 0.01530 0.00697 0.00215 0.07019 0.00144 0.01382 0.02507WATTEL_AUTONOMOUS_THYROID_ADENOMA_DN
0.00000 0.00000 0.00000 0.00000 0.10670 0.01248 0.05114 0.00107 0.02690PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00032 0.00081 0.00005 0.00004 0.09026 0.17601 0.00033 0.00050 0.00492CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN
0.00000 0.00000 0.00000 0.00000 0.00000 0.06686 0.02646 0.00070 0.00000AMIT_EGF_RESPONSE_60_MCF10A
0.03435 0.00001 0.00034 0.00008 0.03916 0.00960 0.00358 0.00151 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP