BICLUSTER_ID : UPREG-98
PATHOGENS /5/ : listeria monocytogenes,escherichia coli,mycobacterium tuberculosis,helicobacter pylori,burkholderia pseudomallei
TARGETS /2/ : CCL20, PTGS2
Gene SetLeading Edge Genes
NETPATH IL 4 PATHWAY DOWNNFKBIA, CCL20, PTGS2, NINJ1, CXCL2
ABRAHAM ALPC VS MULTIPLE MYELOMA UP
KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION
NOJIMA SFRP2 TARGETS UP
CHEN HOXA5 TARGETS 6HR UP
MISSIAGLIA REGULATED BY METHYLATION UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP
SMIRNOV CIRCULATING ENDOTHELIOCYTES IN CANCER UP
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING UP
MAHAJAN RESPONSE TO IL1A UP
VANHARANTA UTERINE FIBROID DN
RODRIGUES THYROID CARCINOMA DN
DORN ADENOVIRUS INFECTION 32HR DN
CROONQUIST STROMAL STIMULATION UP
SA MMP CYTOKINE CONNECTION
HALMOS CEBPA TARGETS UP
RASHI RESPONSE TO IONIZING RADIATION 2
LINDSTEDT DENDRITIC CELL MATURATION A
ZHANG RESPONSE TO CANTHARIDIN UP
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL UP
SAGIV CD24 TARGETS DN
ELVIDGE HYPOXIA UP
HORIUCHI WTAP TARGETS UP
IYENGAR RESPONSE TO ADIPOCYTE FACTORS
XU HGF TARGETS REPRESSED BY AKT1 UP
AMIT EGF RESPONSE 40 HELA
NETPATH IL 7 PATHWAY UP
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 5
MAHADEVAN RESPONSE TO MP470 DN
THEILGAARD NEUTROPHIL AT SKIN WOUND UP
HARRIS HYPOXIA
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLACK UP
FRIDMAN IMMORTALIZATION DN
HINATA NFKB TARGETS KERATINOCYTE UP
NCI REGULATED PROTEOLYSIS OF P75NTR
DORN ADENOVIRUS INFECTION 48HR DN
AMIT EGF RESPONSE 20 HELA
MURATA VIRULENCE OF H PILORI
OSADA ASCL1 TARGETS DN
AMIT SERUM RESPONSE 60 MCF10A
NAGASHIMA NRG1 SIGNALING UP
SOUCEK MYC TARGETS
DUTTA APOPTOSIS VIA NFKB
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR DN
ZERBINI RESPONSE TO SULINDAC UP
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS MAGENTA UP
CROMER TUMORIGENESIS UP
DIRMEIER LMP1 RESPONSE EARLY
MAHADEVAN RESPONSE TO MP470 UP
FERRARI RESPONSE TO FENRETINIDE UP
BILD HRAS ONCOGENIC SIGNATURE
ZHOU INFLAMMATORY RESPONSE LIVE UP
ONDER CDH1 TARGETS 3 DN
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP
AMIT EGF RESPONSE 120 HELA
DAUER STAT3 TARGETS UP
ZHANG ANTIVIRAL RESPONSE TO RIBAVIRIN DN
HELLEBREKERS SILENCED DURING TUMOR ANGIOGENESIS
VART KSHV INFECTION ANGIOGENIC MARKERS DN
MENSE HYPOXIA UP
PODAR RESPONSE TO ADAPHOSTIN UP
BERENJENO TRANSFORMED BY RHOA FOREVER DN
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL
AMIT EGF RESPONSE 60 HELA
DAZARD UV RESPONSE CLUSTER G2
CHEN HOXA5 TARGETS 9HR UP
LEE SP4 THYMOCYTE
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS TURQUOISE UP
TAVOR CEBPA TARGETS UP
AMIT SERUM RESPONSE 40 MCF10A
SEKI INFLAMMATORY RESPONSE LPS UP
OSAWA TNF TARGETS
GRAHAM CML QUIESCENT VS CML DIVIDING UP
CONCANNON APOPTOSIS BY EPOXOMICIN UP
BROWNE HCMV INFECTION 4HR UP
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP
GESERICK TERT TARGETS DN
SENESE HDAC1 AND HDAC2 TARGETS UP
CLASPER LYMPHATIC VESSELS DURING METASTASIS UP
AMIT SERUM RESPONSE 120 MCF10A
BROWNE HCMV INFECTION 2HR UP
HAHTOLA MYCOSIS FUNGOIDES CD4 UP
SESTO RESPONSE TO UV C3
KIM WT1 TARGETS UP
VERHAAK AML WITH NPM1 MUTATED UP
GEISS RESPONSE TO DSRNA UP
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN
XU HGF SIGNALING NOT VIA AKT1 6HR
KOBAYASHI EGFR SIGNALING 6HR DN
GERY CEBP TARGETSATF3, CXCL1, GADD45G, BTG2
ZHOU INFLAMMATORY RESPONSE FIMA UP
HESS TARGETS OF HOXA9 AND MEIS1 DN
DASU IL6 SIGNALING UP
ELVIDGE HYPOXIA BY DMOG UP
AMIT EGF RESPONSE 120 MCF10A
TIAN TNF SIGNALING VIA NFKB
HUMMEL BURKITTS LYMPHOMA DN
GRAHAM CML QUIESCENT VS NORMAL DIVIDING UP
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN
NAGASHIMA EGF SIGNALING UP
AMIT DELAYED EARLY GENES
PRAMOONJAGO SOX4 TARGETS UP
KIM WT1 TARGETS 8HR UP
PICCALUGA ANGIOIMMUNOBLASTIC LYMPHOMA DN
HINATA NFKB TARGETS FIBROBLAST UP
AMIT EGF RESPONSE 60 MCF10A
Color legend
q-value10.20.050.010.0010.0001
Color
TABLE OF Q-VALUES
helicobacter pylori kx1 mgepburkholderia pseudomalleilisteria monocytogenesmycobacterium tuberculosishelicobacter pylori kx2 mgepescherichia coliGeneSet Name
0.00002 0.16712 0.00001 0.00000 0.00009 0.00000NETPATH_IL_4_PATHWAY_DOWN
0.03618 0.00462 0.06377 0.00975 0.10042 0.06486ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP
0.02218 0.02392 0.02915 0.00225 0.00022 0.00000KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION
0.00032 0.00000 0.02668 0.00000 0.00000 0.00018NOJIMA_SFRP2_TARGETS_UP
0.00126 0.01125 0.00069 0.00079 0.00788 0.13852CHEN_HOXA5_TARGETS_6HR_UP
0.00725 0.00964 0.00001 0.00000 0.00396 0.00000MISSIAGLIA_REGULATED_BY_METHYLATION_UP
0.00008 0.01050 0.00001 0.00000 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP
0.07692 0.13459 0.00015 0.00000 0.06739 0.01400SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP
0.03509 0.00002 0.00023 0.00002 0.00541 0.00000GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00517 0.01913 0.00046 0.00132 0.00001 0.00000MAHAJAN_RESPONSE_TO_IL1A_UP
0.00544 0.10491 0.01117 0.00382 0.00272 0.00612VANHARANTA_UTERINE_FIBROID_DN
0.00156 0.00019 0.00235 0.01698 0.00189 0.01801RODRIGUES_THYROID_CARCINOMA_DN
0.00013 0.19819 0.01095 0.00008 0.00009 0.00003DORN_ADENOVIRUS_INFECTION_32HR_DN
0.03674 0.02367 0.05925 0.00025 0.05041 0.00003CROONQUIST_STROMAL_STIMULATION_UP
0.01005 0.13793 0.04438 0.00814 0.11687 0.00133SA_MMP_CYTOKINE_CONNECTION
0.01235 0.11122 0.01542 0.01212 0.03870 0.00001HALMOS_CEBPA_TARGETS_UP
0.00000 0.16626 0.04054 0.00000 0.00000 0.00000RASHI_RESPONSE_TO_IONIZING_RADIATION_2
0.00015 0.00750 0.00000 0.00000 0.00000 0.00000LINDSTEDT_DENDRITIC_CELL_MATURATION_A
0.00152 0.16617 0.17841 0.00019 0.00028 0.09441ZHANG_RESPONSE_TO_CANTHARIDIN_UP
0.00132 0.09910 0.00043 0.00196 0.02379 0.00127LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP
0.03235 0.00252 0.09742 0.00000 0.00458 0.00010SAGIV_CD24_TARGETS_DN
0.00083 0.02727 0.00023 0.00052 0.00095 0.01124ELVIDGE_HYPOXIA_UP
0.02539 0.03425 0.01805 0.00000 0.01380 0.00002HORIUCHI_WTAP_TARGETS_UP
0.00293 0.09871 0.01417 0.00217 0.01339 0.00026IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS
0.07397 0.06915 0.07527 0.06625 0.05676 0.00330XU_HGF_TARGETS_REPRESSED_BY_AKT1_UP
0.00125 0.00290 0.00068 0.00000 0.00053 0.00000AMIT_EGF_RESPONSE_40_HELA
0.00294 0.16021 0.09197 0.00856 0.00019 0.00000NETPATH_IL_7_PATHWAY_UP
0.00012 0.03172 0.15820 0.05325 0.00313 0.03327YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_5
0.00340 0.00025 0.01146 0.00000 0.00005 0.00317MAHADEVAN_RESPONSE_TO_MP470_DN
0.00000 0.12979 0.00000 0.00000 0.00010 0.00000THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP
0.00027 0.16949 0.00000 0.00067 0.00009 0.00034HARRIS_HYPOXIA
0.05246 0.14993 0.00166 0.00033 0.13289 0.17907GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP
0.07711 0.18625 0.16402 0.00089 0.14744 0.00651FRIDMAN_IMMORTALIZATION_DN
0.00002 0.00143 0.00001 0.00000 0.00000 0.00000HINATA_NFKB_TARGETS_KERATINOCYTE_UP
0.10723 0.04305 0.17033 0.17760 0.13573 0.01182NCI_REGULATED_PROTEOLYSIS_OF_P75NTR
0.00007 0.14963 0.00579 0.00008 0.00009 0.00089DORN_ADENOVIRUS_INFECTION_48HR_DN
0.02197 0.02388 0.02894 0.00486 0.00435 0.00089AMIT_EGF_RESPONSE_20_HELA
0.01632 0.16529 0.02078 0.05724 0.10066 0.00130MURATA_VIRULENCE_OF_H_PILORI
0.10172 0.01311 0.04416 0.00021 0.14030 0.00002OSADA_ASCL1_TARGETS_DN
0.00013 0.00292 0.02234 0.00001 0.00000 0.00109AMIT_SERUM_RESPONSE_60_MCF10A
0.00000 0.00002 0.00045 0.00000 0.00000 0.00000NAGASHIMA_NRG1_SIGNALING_UP
0.00011 0.03675 0.09270 0.02521 0.00002 0.00037SOUCEK_MYC_TARGETS
0.00000 0.07914 0.01422 0.00002 0.00000 0.00000DUTTA_APOPTOSIS_VIA_NFKB
0.00543 0.05436 0.00142 0.00228 0.01992 0.05842TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN
0.00318 0.11717 0.05033 0.04554 0.00100 0.02814ZERBINI_RESPONSE_TO_SULINDAC_UP
0.04809 0.00142 0.00178 0.00022 0.04284 0.02827GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP
0.11955 0.04511 0.01616 0.01999 0.10547 0.00002CROMER_TUMORIGENESIS_UP
0.00157 0.04849 0.00199 0.00000 0.00124 0.00000DIRMEIER_LMP1_RESPONSE_EARLY
0.00002 0.14983 0.00004 0.00004 0.00001 0.00000MAHADEVAN_RESPONSE_TO_MP470_UP
0.00008 0.05896 0.06128 0.00018 0.00002 0.00016FERRARI_RESPONSE_TO_FENRETINIDE_UP
0.00029 0.01123 0.00000 0.00000 0.00132 0.00000BILD_HRAS_ONCOGENIC_SIGNATURE
0.00000 0.00909 0.00000 0.00002 0.00000 0.00000ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP
0.00085 0.05647 0.00011 0.10086 0.00020 0.00000ONDER_CDH1_TARGETS_3_DN
0.00007 0.00000 0.00000 0.00000 0.00044 0.00155GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP
0.00003 0.00027 0.02592 0.00000 0.00007 0.00046AMIT_EGF_RESPONSE_120_HELA
0.00067 0.00256 0.00016 0.00000 0.00008 0.00003DAUER_STAT3_TARGETS_UP
0.05403 0.02735 0.05104 0.00534 0.01763 0.00000ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN
0.04115 0.09145 0.16188 0.00036 0.11815 0.00004HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS
0.17286 0.12995 0.06178 0.13415 0.05576 0.08667VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN
0.00855 0.00659 0.01410 0.00000 0.00036 0.09188MENSE_HYPOXIA_UP
0.00015 0.00000 0.00004 0.00000 0.00000 0.01026PODAR_RESPONSE_TO_ADAPHOSTIN_UP
0.08229 0.00758 0.03353 0.08977 0.02345 0.00016BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN
0.00015 0.17112 0.03814 0.00008 0.00073 0.08973ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN
0.00516 0.07309 0.06528 0.02942 0.00231 0.00247REACTOME_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL
0.00002 0.02574 0.02795 0.00000 0.00000 0.00523AMIT_EGF_RESPONSE_60_HELA
0.00079 0.02586 0.04745 0.01541 0.00000 0.00004DAZARD_UV_RESPONSE_CLUSTER_G2
0.00000 0.03571 0.00000 0.00006 0.00000 0.00050CHEN_HOXA5_TARGETS_9HR_UP
0.09234 0.02590 0.06132 0.00049 0.13635 0.05781LEE_SP4_THYMOCYTE
0.00151 0.00017 0.00001 0.00000 0.00092 0.10160GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP
0.03788 0.08082 0.00125 0.00011 0.04908 0.00020TAVOR_CEBPA_TARGETS_UP
0.00874 0.06818 0.00799 0.00000 0.00219 0.00142AMIT_SERUM_RESPONSE_40_MCF10A
0.00000 0.01261 0.00000 0.00000 0.00000 0.00000SEKI_INFLAMMATORY_RESPONSE_LPS_UP
0.06007 0.03652 0.05254 0.07502 0.01263 0.00142OSAWA_TNF_TARGETS
0.00937 0.00000 0.00097 0.00000 0.00677 0.00000GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP
0.00002 0.00000 0.00060 0.00028 0.00000 0.08735CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP
0.00261 0.02223 0.00001 0.00024 0.04014 0.00000BROWNE_HCMV_INFECTION_4HR_UP
0.00000 0.00139 0.00000 0.00000 0.00000 0.00000ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP
0.00257 0.00623 0.02216 0.00002 0.00002 0.00083GESERICK_TERT_TARGETS_DN
0.02541 0.10073 0.00023 0.01303 0.00621 0.00002SENESE_HDAC1_AND_HDAC2_TARGETS_UP
0.01277 0.02356 0.15408 0.05159 0.03925 0.03242CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP
0.00289 0.02599 0.00040 0.00013 0.00109 0.00011AMIT_SERUM_RESPONSE_120_MCF10A
0.00034 0.05164 0.02059 0.00000 0.00890 0.00014BROWNE_HCMV_INFECTION_2HR_UP
0.00215 0.00000 0.00000 0.00000 0.00008 0.00000HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP
0.00438 0.00000 0.00002 0.00000 0.00018 0.00001SESTO_RESPONSE_TO_UV_C3
0.00000 0.05021 0.01564 0.00007 0.00000 0.00002KIM_WT1_TARGETS_UP
0.00063 0.13600 0.00000 0.00000 0.00145 0.00000VERHAAK_AML_WITH_NPM1_MUTATED_UP
0.00000 0.11502 0.00027 0.00000 0.00000 0.00000GEISS_RESPONSE_TO_DSRNA_UP
0.00000 0.00019 0.00007 0.00000 0.00000 0.00044UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN
0.00018 0.00980 0.00146 0.00239 0.00823 0.00132XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR
0.00064 0.01348 0.01417 0.00020 0.00002 0.00015KOBAYASHI_EGFR_SIGNALING_6HR_DN
0.00133 0.00015 0.00163 0.00000 0.00038 0.01389GERY_CEBP_TARGETS
0.00157 0.00000 0.00125 0.00047 0.00011 0.00000ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP
0.04632 0.08705 0.00001 0.00000 0.11528 0.08966HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN
0.07974 0.03694 0.00595 0.00006 0.10056 0.00015DASU_IL6_SIGNALING_UP
0.00023 0.03396 0.00142 0.00043 0.00024 0.01098ELVIDGE_HYPOXIA_BY_DMOG_UP
0.02386 0.05040 0.00423 0.03451 0.00229 0.00004AMIT_EGF_RESPONSE_120_MCF10A
0.00000 0.00000 0.00054 0.00000 0.00000 0.00000TIAN_TNF_SIGNALING_VIA_NFKB
0.02445 0.09754 0.17259 0.00035 0.07423 0.00005HUMMEL_BURKITTS_LYMPHOMA_DN
0.00000 0.00000 0.00001 0.00002 0.00000 0.00000GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP
0.00010 0.02880 0.00001 0.00000 0.00000 0.00000OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_DN
0.00000 0.00000 0.00001 0.00000 0.00000 0.00003NAGASHIMA_EGF_SIGNALING_UP
0.00013 0.00501 0.00200 0.00001 0.00009 0.00082AMIT_DELAYED_EARLY_GENES
0.00000 0.01688 0.01526 0.00000 0.00000 0.00005PRAMOONJAGO_SOX4_TARGETS_UP
0.00306 0.00345 0.00699 0.00125 0.00689 0.07735KIM_WT1_TARGETS_8HR_UP
0.00002 0.09787 0.00887 0.00000 0.00000 0.02690PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN
0.00000 0.03538 0.00031 0.00000 0.00009 0.00000HINATA_NFKB_TARGETS_FIBROBLAST_UP
0.00002 0.00375 0.01523 0.00004 0.00000 0.00000AMIT_EGF_RESPONSE_60_MCF10A