IL-13→Interleukin-10→Nucleoside Diphosphate Sugars→poly-ADP-ribose

• 11681489(IL-13): The increased interleukin-13 in patients with systemic lupus erythematosus: relations to other Th1-, Th2-related cytokines and clinical findings.

  The levels of interleukin-13 (IL-13) in patients with systemic lupus erythematosus (SLE) were examined and related to other Th1 - / Th2 - related cytokines , clinical manifestations and other markers.

• 11990459(Interleukin-10): The expression and significance of intracellular T helper cytokines in systemic lupus erythematosus.

  To analyze the Th1 and Th2 paradigm of peripheral T helper cells in patients with systemic lupus erythematosus (SLE).

• 2765003(Nucleoside Diphosphate Sugars): Altered metabolism of poly(ADP-ribose) in the peripheral blood lymphocytes of patients with systemic lupus erythematosus.

  The synthesis and degradation of poly (ADP-ribose) in this crude lysate , measured by the incorporation of 3H-labeled NAD into acid-precipitable counts , was compared in 18 patients with systemic lupus erythematosus (SLE) , 10 patients with rheumatoid arthritis , and in 10 control patients without rheumatoid arthritis.

• 6458707(poly-ADP-ribose): Effects of nicotinamide on NAD and poly(ADP-ribose) metabolism in DNA-damaged human lymphocytes.

  Thus under conditions that it enhances unscheduled DNA synthesis , nicotinamide causes marked effects on the metabolism of NAD + and poly (ADP-ribose).