IL-13→Somatomedins→Poly(ADP-ribose) Polymerases→poly-ADP-ribose

• 15307936(IL-13): T-lymphocyte cytokine production patterns in nonimmune severe hypothyroid state and after thyroid hormone replacement therapy.

  Peripheral blood mononuclear cell (PBMC) cultures and intracellular cytokine detection by flow cytometry before and after thyroid hormone replacement therapy were performed (free thyroxine (FT4) 0.030 + / - 0.034 ng/dL , versus FT4 : 2.16 + / - 0.68 ng/dL).

• 6354519(Somatomedins): Growth hormone secretion and plasma somatomedin-C in primary hypothyroidism.

  With thyroid hormone therapy the mean plasma somatomedin-C level increased four-fold (1.00 + / - 0.43 U/ml).

• 7945304(Poly(ADP-ribose) Polymerases): Hepatic poly(ADP-ribose) polymerase activity in rat is controlled by thyroid hormones.

  The pretreatment with the antagonist amiodarone suppressed the hormone effect , suggesting that nuclear receptors could mediate poly (ADP-ribose) polymerase activity.

• 228176(poly-ADP-ribose): Characterisation of poly(ADP-Rib) polymerase activity in nuclei from the slime mould Dictyostelium discoideum.

  The optimum incubation conditions for the poly (ADP-Rib) polymerase were determined.