MMP-3→poly-ADP-ribose

• 16603129(MMP-3): Crystal structures of the catalytic domain of human stromelysin-1 (MMP-3) and collagenase-3 (MMP-13) with a hydroxamic acid inhibitor SM-25453.

  Crystal structures of the catalytic domain of human stromelysin-1 (MMP-3) and collagenase-3 (MMP-13) with a hydroxamic acid inhibitor SM-25453 have been solved at 2.01 and 2.37 A resolutions , respectively.

• 20092359(poly-ADP-ribose): Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888.

  We used X-ray crystallography to determine two structures of the catalytic domain of human PARP2 : the complexes with PARP inhibitors 3-aminobenzamide and ABT-888.