MCP1→Intercellular Adhesion Molecule-1→poly-ADP-ribose

• 19118698(MCP1): Association of vitreous inflammatory factors with diabetic macular edema.

  VEGF and ICAM-1 had a stronger influence than the other factors.

• 16734619(Intercellular Adhesion Molecule-1): Cytokines differentially regulate ICAM-1 and VCAM-1 expression on human gingival fibroblasts.

  This study aimed to assess which cytokines regulate ICAM-1 and VCAM-1 expression on HGF.

• 11403206(poly-ADP-ribose): Poly ADP ribose-polymerase inhibitors prevent the upregulation of ICAM-1 and E-selectin in response to Th1 cytokine stimulation.

  We studied the role of poly-ADP-ribose polymerase (PARP) in the mobilization of ICAM-1 , VCAM-1 , and E-selectin by TNF-alpha and IL-1beta in cultured human endothelial cells.