IL-8→CX3CL1 protein, human→NF-kappa B→poly-ADP-ribose

• 19587833(IL-8): Monocyte chemoattractant protein 1 is a prognostic marker in ANCA-associated small vessel vasculitis.

  Raised MCP-1 levels are associated with poor prognosis and possibly also with relapse tendency.

• 15353578(CX3CL1 protein, human): Urinary monocyte chemoattractant protein-1 (MCP-1) is a marker of active renal vasculitis.

  There were no differences in serum concentrations of MCP-1 between these groups.

• 10469356(NF-kappa B): c-Rel and p65 trans-activate the monocyte chemoattractant protein-1 gene in interleukin-1 stimulated mesangial cells.

  Specific members of the nuclear factor kappaB/rel (NF-kappaB) proteins may regulate MCP-1 expression in a stimulus - and tissue-specific manner.

• 12581860(poly-ADP-ribose): gamma-Irradiation-induced DNA damage enhances NO production via NF-kappaB activation in RAW264.7 cells.

  Nuclear factor kappa B (NF-kappaB) activation was induced 1 h after gamma-irradiation dose-dependently , which was detected by the degradation of I-kappaB.