IL-8→Ki-67 Antigen→Poly(ADP-ribose) Polymerases→poly-ADP-ribose

• 19760951(IL-8): Cytokine evaluation in liver cirrhosis and hepatocellular carcinoma.

  RESULTS : In total , 81 patients were included , including 9 healthy controls , 36 LC patients , and 36 HCC patients.

• 11339428(Ki-67 Antigen): Enhanced polyadenosine diphosphate-ribosylation in cirrhotic liver and carcinoma tissues in patients with hepatocellular carcinoma.

  METHODS : Hepatocellular carcinoma and LC tissues were sampled from 19 patients with HCC.

• 10847440(Poly(ADP-ribose) Polymerases): Enhancement of poly-adenosine diphosphate-ribosylation in human hepatocellular carcinoma.

  RESULTS : Several proteins were ADP-ribosylated in human HCC tissues.

• 3000421(poly-ADP-ribose): Nonenzymic adenosine 5'-diphosphate ribosylation of poly(adenosine diphosphate ribose).

  RNA is also spontaneously ADP-ribosylated , but not DNA.