MCP1→Poly(ADP-ribose) Polymerases→1-Naphthylamine→poly-ADP-ribose

• 20029451(MCP1): Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2-/- mice.

  Cerebral inflammation involves molecular cascades contributing to progressive damage after traumatic brain injury (TBI).

• 11450092(Poly(ADP-ribose) Polymerases): Traumatic brain injury in mice deficient in poly-ADP(ribose) polymerase: a preliminary report.

  PARP contributes to neuronal cell death in vivo after cerebral ischemia/reperfusion , however , the role of PARP in the pathogenesis of traumatic brain injury (TBI) is unknown.

• 12686864(1-Naphthylamine): The effect of poly (adenosine diphosphate-ribose) polymerase inhibitors on biochemical changes in testicular ischemia-reperfusion injury.

  We evaluated the efficacy of poly (ADP-ribose) polymerase inhibitors on biochemical changes in testicular ischemia-reperfusion injury.

• 6299867(poly-ADP-ribose): Effect of poly(ADP-ribose) synthetase inhibitor administration to rats before and after injection of alloxan and streptozotocin on islet proinsulin synthesis.

  Pretreatment with poly (ADP-ribose) synthetase inhibitors was found to protect against alloxan - or streptozotocin-induced decrease in proinsulin synthesis.