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20226760(IFN-gamma): The leukotriene B4 receptor, BLT1, is required for the induction of experimental autoimmune encephalomyelitis.
Our findings provide a novel therapeutic option for the treatment of multiple sclerosis and other T (H) 17-mediated diseases.
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9058773(Antibodies): Aggravation of murine experimental allergic encephalomyelitis by administration of T-cell receptor gammadelta-specific antibody.
Recent reports demonstrated accumulation of gammadelta T-cells in active multiple sclerosis (MS) plaque and infiltration into brains with EAE.
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11431007(Poly(ADP-ribose) Polymerases): Role of poly(ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis.
Moreover , drug treatment lowered iNOS activity and decreased cell infiltration in cervical spinal tissues from EAE-sensitized animals.
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6299867(poly-ADP-ribose): Effect of poly(ADP-ribose) synthetase inhibitor administration to rats before and after injection of alloxan and streptozotocin on islet proinsulin synthesis.
Proinsulin synthesis was decreased in islets from rats treated with alloxan or streptozotocin.