Albendazole treatment of individuals with human immunodeficiency virus type 1 (HIV-1) and Ascaris lumbricoides co-infection has led to significantly improved CD4 (+) cell counts and a trend for lower plasma HIV-1 RNA levels in a previous randomized placebo-controlled trial.
The relationship between T cell activation and human immunodeficiency virus type 1 (HIV-1) replication was studied in HIV-infected subjects , 20 with and 10 without anti-HIV treatment.
Employing an artificially constructed DNA in which the chloramphenicol acetyltransferase gene was placed under the control of the HIV-1 long terminal repeat , we analyzed the induction process in HeLa cells and found that inhibitors of poly (ADP-ribose) polymerase suppressed UV-induced HIV-1 gene expression but not tat-mediated expression.
23 , 13 -- 28) ; poly (ADP-ribose) polymerase , however , has been found only in eucaryotes.