IL-1 alpha→Antibodies, Monoclonal→Antibodies, Monoclonal→poly-ADP-ribose

• 7524240(IL-1+alpha): Production and application of monoclonal antibodies to ovine interleukin-1 alpha and interleukin-1 beta.

  Monoclonal antibodies (mAbs) were raised against recombinant ovine interleukin-1 alpha and beta (ovIL-1 alpha and ovIL-1 beta).

• 7507085(Antibodies, Monoclonal): Production of monoclonal antibodies recognising different epitopes present on insulin-like growth factor 1.

  Monoclonal antibodies (MAbs) were generated against recombinant human insulin-like growth factor 1 (IGF-1) by fusion of NS-1 myeloma cells with spleen cells from BALB/c X DBA mice immunised with recombinant IGF-1 and synthetic peptide sequences derived from the published amino acid sequence of IGF-1.

• 6299712(Antibodies, Monoclonal): Interactions of a monoclonal antibody to the insulin receptor with receptors for insulin-like growth factors.

  A monoclonal antibody to the human insulin receptor was tested for its ability to inhibit the binding of 125I-insulin-like growth factor I (IGF-I) and 125I-insulin-like growth factor II (IGF-II) to their receptors in human placenta membranes and cultured human IM-9 lymphocytes.

• 6262062(poly-ADP-ribose): Insulin receptor down-regulation, prevention at a post-receptor site.

  Spermine decreased the number of insulin receptors in IM-9 cells , but this effect was not inhibited by nicotinamide.