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17869651(IL-8): Association of IL-8 (-251)T/A polymorphism with susceptibility to and aggressiveness of nasopharyngeal carcinoma.
The presence of the IL-8 (-251) AA genotype was highly associated with elevated NPC risk for male patients.
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12530093(Interleukin-8): The role of interleukin-8 in the initiation and progression of human cutaneous melanoma.
The role of IL-8 in human patients is not yet clear.
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8877727(Interleukin-8): Interferon-beta prevents the upregulation of interleukin-8 expression in human melanoma cells.
These data suggest that the expression of IL-8 in human melanoma cells can be upregulated by inflammatory cytokines and that IFN-alpha and IFN-beta can counterregulate this stimulation.
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12804771(STAT2): Measles virus V protein blocks interferon (IFN)-alpha/beta but not IFN-gamma signaling by inhibiting STAT1 and STAT2 phosphorylation.
In contrast , tyrosine phosphorylation of both STAT1 and STAT2 was inhibited in these cells after IFN-beta stimulation.