IL-8→Smoke→Contraceptive Agents, Female→BRCA1

• 18415826(IL-8): Effect of budesonide and formoterol on IL-6 and IL-8 release from primary bronchial epithelial cells.

  Primary bronchial epithelial cells (PBEC) were stimulated with organic dust and incubated with budesonide , formoterol , and the combination of both drugs.

• 9154890(Smoke): Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells.

  We hypothesized that exposure to cigarette smoke might initiate release of inflammatory mediators by bronchial epithelial cells.

• 3591776(Contraceptive Agents, Female): Cigarette smoking and the risk of epithelial ovarian cancer.

  Whether cigarette smoking has any effect on the development of ovarian cancer has not been adequately evaluated.

• 15095307(BRCA1): Smoking and the risk of breast cancer among carriers of BRCA mutations.

  The effect of cigarette smoking on the risk of breast cancer is controversial , although most studies show little or no effect.