IL-8→Interferon-gamma→Tumor Necrosis Factor-alpha→STAT2

• 18837094(IL-8): Genetic polymorphism of MCP-1-2518, IL-8-251 and susceptibility to acute pancreatitis: a pilot study in population of Suzhou, China.

  METHODS : A case-control study was conducted to compare the distribution of genotype and genetic frequency of MCP-1-2518A / G , IL-8-251A / T gene polymorphism among AP (n = 101) , including mild AP (n = 78) and severe AP (n = 23) and control healthy individuals (n = 120) with polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and DNA sequencing , and analyze the relationship between the MCP-1-2518A / G , IL-8-251A / T gene polymorphism and the susceptibility to AP.

• 19681846(Interferon-gamma): Association of interferon-gamma +874A polymorphism with the risk of developing cervical cancer in north-Indian population.

  Therefore , we aimed to investigate the association of IFN-gamma T/A gene polymorphism with the risk of cervical cancer.

• 15890243(Tumor Necrosis Factor-alpha): Polymorphism in the genes of alpha and beta tumor necrosis factors (TNF-alpha and TNF-beta) and gamma interferon (IFN-gamma) among Iranian women with breast cancer.

  The association of the polymorphism in the genes of TNF-alpha , TNF-beta and IFN-gamma with breast cancer was investigated in the present study.

• 12804771(STAT2): Measles virus V protein blocks interferon (IFN)-alpha/beta but not IFN-gamma signaling by inhibiting STAT1 and STAT2 phosphorylation.

  We found that expression of V protein inhibited interferon (IFN) - alpha/beta signaling but not IFN-gamma signaling.