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19861615(IL-1+beta): Interleukin-1 beta single-nucleotide polymorphism's C allele is associated with elevated risk of gastric cancer in Helicobacter pylori-infected Peruvians.
No such data exist from Peru , a developing country with a population genotypically different from others studied and with a high prevalence of Helicobacter pylori infection and gastric cancer.
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1773951(Interleukin-6): Mucosal tumour necrosis factor alpha and interleukin-6 in patients with Helicobacter pylori associated gastritis.
Inflammatory cytokines generated locally within the gastric mucosa could be relevant to the gastric physiology of H pylori infection.
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11699878(Tumor Necrosis Factor-alpha): Role of ERK and p38 mitogen-activated protein kinase cascades in gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide.
The findings suggest that the p38 MAPK signaling pathway plays a key role in the mediation of gastric mucosal inflammatory reaction to H. pylori infection.
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12130576(ATF2): p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function.
These results suggest that osteoclast function is induced through a mechanism independent of p38 MAPK-mediated signaling.