IL-1 beta→Interleukin-1→p38 Mitogen-Activated Protein Kinases→c-fos

• 20085044(IL-1+beta): Effect of peritoneal lavage on TNF-alpha, IL-1beta, and IL-6 levels and mortality in intraabdominal infections.

  The aim of this study is to investigate the effect of peritoneal lavage on TNF-alpha , IL-1beta , and IL-6 levels and mortality when the source control has or has not been established.

• 10807411(Interleukin-1): Induction of signal transduction pathways in rat gastric epithelial cells stimulated with interleukin-1beta.

  AIM : To investigate whether IL-1beta activates MAP kinases (extracellular signal-regulated kinases (ERKs) , c-Jun NH2-terminal kinases (JNKs) and p38 MAP kinase (p38 MAPK)) and nuclear factor (NF) - kappaB.

• 12393099(p38 Mitogen-Activated Protein Kinases): MCP-1 induces activation of MAP-kinases ERK, JNK and p38 MAPK in human endothelial cells.

  We investigated whether MCP-1 activated the three major mitogen activated protein (MAP) - kinases extracellular signal-regulated kinase (ERK) , c-Jun amino terminal kinase (JNK) and p38 MAPK.

• 19336001(c-fos): Pyrrolidine dithiocarbamate-induced activation of ERK and increased expression of c-Fos in mouse embryonic stem cells.

  Among the three different mitogen-activated protein kinase (MAPK) pathways , including the extracellular-signal-regulated kinase (ERK) , p38 MAP kinase , and stress-activated protein kinase (SAPK) / Jun N-terminal kinase (JNK) pathways , only the ERK pathway was significantly activated in mouse ES cells after stimulation with PDTC.