RESULTS : Each patient had a mean of 9 brain tissue TNF-alpha measurements obtained over an average of 72h of monitoring.
The concentrations of TNF-alpha in the brain and CSF were significantly higher in parkinsonian patients than those in controls.
Synthesized TNF-alpha might directly act on peripheral nerve glia via TNF receptors , but the inherent mechanisms remain unknown.
Diabetes (BB ; i.e. type 1) confers on the peripheral nerve an increased susceptibility to nerve compression indicated by an increased expression of stained ATF3 neurons and Schwann cells.